Image
Brenda Sanchez
Former Developmental Core Manager (2002-2025)
CFAR offered a general Pilot Award program from 1994 to 2017 and funded 82 early stage investigators.
In 2022, CFAR initiated a new program: Pilot Award for Investigators New to HIV.
82 Awards
-
HIV-1 Genital Shedding in Women Before and After Treatment for Cervical Dysplasia
HIV-1 Genital Shedding in Women Before and After Treatment for Cervical Dysplasia
Abstract
The majority of the global HIV epidemic is occurring in sub-Saharan Africa, where the main route of transmission is heterosexual intercourse. An understanding of factors impacting transmission risk is necessary for effective prevention strategies, especially in countries such as Kenya, where the majority of infected individuals are in relationships with HIV-negative partners. One of the factors thought to be associated with sexual transmission is the presence and quantity of HIV-1 in the genital tract.
-
Investigation of HIV Levels, Latent Reservoirs, and Mechanisms of Latency in the Gut
Investigation of HIV Levels, Latent Reservoirs, and Mechanisms of Latency in the Gut
Abstract
Though combined antiretroviral therapy (ART) has reduced both morbidity and mortality due to HIV, ART does not lead to eradication or restore normal health to HIV-infected individuals. Given the staggering health and financial costs of HIV, it seems imperative to explore new therapies that can possibly lead to viral eradication. Obstacles to eradication include latent infection in resting memory CD4+ T cells and the presence of other cell types or organs that serve as sanctuary sites for virus.
-
Sexual Transmission of Drug Resistant Virus among HIV-Positive Men and Women
Sexual Transmission of Drug Resistant Virus among HIV-Positive Men and Women
Abstract
-
Inhibitors of APOBEC3C and HIV Mutation
Inhibitors of APOBEC3C and HIV Mutation
Abstract
-
Novel Lipopeptide Epitopes to the MPR Region of GP41: Characterization of Antibody Titer, Lipid Cross-Reactivity and HIV Neutralization
Novel Lipopeptide Epitopes to the MPR Region of GP41: Characterization of Antibody Titer, Lipid Cross-Reactivity and HIV Neutralization
Abstract
-
Identifying Novel Allosteric Inhibitors of Kaposi's Sarcoma-associated Herpesvirus Protease
Identifying Novel Allosteric Inhibitors of Kaposi's Sarcoma-associated Herpesvirus Protease
Abstract
Publications:
-
Body Fat Changes in HIV-infected Individuals after initiating ART in Southwestern Uganda
Body Fat Changes in HIV-infected Individuals after initiating ART in Southwestern Uganda
Abstract
-
Kisumu Street Children: A Pilot Study of STIs and HIV in Social Context
Kisumu Street Children: A Pilot Study of STIs and HIV in Social Context
Abstract
There is wide agreement that street children carry a greater risk of HIV/AIDS infection than their peers, yet this sub-epidemic has been largely ignored by the HIV research community, in part due to their marginalized status. Our ability to design interventions that will improve the health of street children is compromised by the absence of answers to fundamental questions, including: What are their rates of HIV and STIs? What are the modifiable social and contextual factors that increase their risk for infection? Given their marginalized status, how can they best be reached and recruited?
-
Identifying Novel Allosteric Inhibitors of Kaposi's Sarcoma-associated Herpesvirus Protease
Identifying Novel Allosteric Inhibitors of Kaposi's Sarcoma-associated Herpesvirus Protease
Abstract
Publications:
-
Body Fat Changes in HIV-infected Individuals after initiating ART in Southwestern Uganda
Body Fat Changes in HIV-infected Individuals after initiating ART in Southwestern Uganda
Abstract