Estimating the Effect of Indoor Residual Spraying on Maternal Mortality, Low-Birthweight and Perinatal Mortality Among HIV-Infected Pregnant Women Living in the HAART Era
Estimating the Effect of Indoor Residual Spraying on Maternal Mortality, Low-Birthweight and Perinatal Mortality Among HIV-Infected Pregnant Women Living in the HAART Era
Abstract
It is well known that children born to women co-infected with HIV and malaria are at increased risk of low birthweight and perinatal death. Preliminary work has shown that indoor residual spraying with insecticide, a well-known malaria control strategy, is associated with 50-71% reduction in low birthweight and 61-90% risk reduction in neonatal mortality among both HIV-infected women and HIV-uninfected women. While potentially important findings, the opportunistic before and after study design approach used is open to issues of confounding.