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Lauren Sterling
Associate Director, UCSF-Bay Area CFAR
Note: Beginning with Fall 2016, The Basic Science program has been combined into the Mentored Scientist Award mechanism - which now has three scientific priority areas for funding: Basic Science, Clinical/ Translational/ Epidemiological/ Behavioral, and Implementation Science.
Below are the awards made under the Basic Science program from 1994 to 2016.
58 Awards
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Expanded Cellular Tropism of Human Immunodeficiency Virus 1 by a Trans-Receptor Mechanism
Expanded Cellular Tropism of Human Immunodeficiency Virus 1 by a Trans-Receptor Mechanism
Abstract
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Role of Double Modified Tat Protein in HIV-1 Transcription
Role of Double Modified Tat Protein in HIV-1 Transcription
Abstract
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Role of Double Modified Tat Protein in HIV-1 Transcription
Role of Double Modified Tat Protein in HIV-1 Transcription
Abstract
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Role of Chromatin Remodeling in HIV Transcriptional Regulation
Role of Chromatin Remodeling in HIV Transcriptional Regulation
Abstract
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Role of Chromatin Remodeling in HIV Transcriptional Regulation
Role of Chromatin Remodeling in HIV Transcriptional Regulation
Abstract
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Differential Regulation of Basal and Tat-mediated HIV Transcription by Acetylation of P-TEFb
Differential Regulation of Basal and Tat-mediated HIV Transcription by Acetylation of P-TEFb
Abstract
We try to understand the mechanisms of HIV transcriptional regulation as target for therapy. The viral transactivator Tat and its interacting cofactors play an important role in HIV transcription. Tat binds to an RNA structure called TAR and recruits the positive elongation factor b (P-TEFb) to HIV-1 transcripts. P-TEFb is composed of the cyclin T1 and cyclin-dependent kinase 9 (CDK9). We identified four acetylation sites in cyclin T1.
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Differential Regulation of Basal and Tat-mediated HIV Transcription by Acetylation of P-TEFb
Differential Regulation of Basal and Tat-mediated HIV Transcription by Acetylation of P-TEFb
Abstract
We try to understand the mechanisms of HIV transcriptional regulation as target for therapy. The viral transactivator Tat and its interacting cofactors play an important role in HIV transcription. Tat binds to an RNA structure called TAR and recruits the positive elongation factor b (P-TEFb) to HIV-1 transcripts. P-TEFb is composed of the cyclin T1 and cyclin-dependent kinase 9 (CDK9). We identified four acetylation sites in cyclin T1.
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The role of transcriptional interference and inhibition of transcriptional elongation in HIV latency
The role of transcriptional interference and inhibition of transcriptional elongation in HIV latency
Abstract
Publications:
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Molecular Biology of HIV Macrophage Infection
Molecular Biology of HIV Macrophage Infection
Abstract
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The Biology of Coreceptors for HIV and Chemokine Receptors in vivo as a Factor in Regulating HIV Disease Progression
The Biology of Coreceptors for HIV and Chemokine Receptors in vivo as a Factor in Regulating HIV Disease Progression
Abstract
Publications: