Note: Beginning with Fall 2016, The Basic Science program has been combined into the Mentored Scientist Award mechanism - which now has three scientific priority areas for funding: Basic Science, Clinical/ Translational/ Epidemiological/ Behavioral, and Implementation Science.
Below are the awards made under the Basic Science program from 1994 to 2016.
58 Awards
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Role of Chromatin Remodeling in HIV Transcriptional Regulation
Role of Chromatin Remodeling in HIV Transcriptional Regulation
Abstract
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Role of Double Modified Tat Protein in HIV-1 Transcription
Role of Double Modified Tat Protein in HIV-1 Transcription
Abstract
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Expanded Cellular Tropism of Human Immunodeficiency Virus 1 by a Trans-Receptor Mechanism
Expanded Cellular Tropism of Human Immunodeficiency Virus 1 by a Trans-Receptor Mechanism
Abstract
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Do Human Natural Killer Cells Acquire Immune Memory to Viral Infections?
Do Human Natural Killer Cells Acquire Immune Memory to Viral Infections?
Abstract
Natural killer (NK) cells have traditionally been considered members of the innate immune system. Recently, in a mouse model of cytomegalovirus, our lab has demonstrated that NK cells undergo clonal expansion during acute viral infection, the population contracts when virus is controlled, but remarkably infection induces a population of "memory" NK cells. These cells are long-lived, respond more robustly when re-challenged, and provide enhanced host protection against re-infection.
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The Role of Autophagy in HIV Infection
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Defining the role of lysine methylation in HIV-1 Tat transactivation
Defining the role of lysine methylation in HIV-1 Tat transactivation
Abstract
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The Biology of Coreceptors for HIV and Chemokine Receptors in vivo as a Factor in Regulating HIV Disease Progression
The Biology of Coreceptors for HIV and Chemokine Receptors in vivo as a Factor in Regulating HIV Disease Progression
Abstract
Publications:
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Transgenic Rabbits and HIV Infection
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The Kinetics of Primary Viremia in Macaques and Sooty Mangabeys Infected with Simian Immunodeficiency Virus
The Kinetics of Primary Viremia in Macaques and Sooty Mangabeys Infected with Simian Immunodeficiency Virus
Abstract
Publications:
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Direct Measurement of Rate of Synthesis and Removal of Circulating HIV in Infected Humans
Direct Measurement of Rate of Synthesis and Removal of Circulating HIV in Infected Humans
Abstract