Note: Beginning with Fall 2016, The Basic Science program has been combined into the Mentored Scientist Award mechanism - which now has three scientific priority areas for funding: Basic Science, Clinical/ Translational/ Epidemiological/ Behavioral, and Implementation Science.
Below are the awards made under the Basic Science program from 1994 to 2016.
58 Awards
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High CD8+ T cell Activation Associates with HIV Disease Outcome
High CD8+ T cell Activation Associates with HIV Disease Outcome
Abstract
Publications:
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Transgenic Rabbits and HIV Infection
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High CD8+ T cell Activation Associates with HIV Disease Outcome
High CD8+ T cell Activation Associates with HIV Disease Outcome
Abstract
Publications:
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Transgenic Rabbits and HIV Infection
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Molecular Biology of HIV Macrophage Infection
Molecular Biology of HIV Macrophage Infection
Abstract
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The Biology of Coreceptors for HIV and Chemokine Receptors in vivo as a Factor in Regulating HIV Disease Progression
The Biology of Coreceptors for HIV and Chemokine Receptors in vivo as a Factor in Regulating HIV Disease Progression
Abstract
Publications:
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Molecular Interactions Between HIV and HPV
Molecular Interactions Between HIV and HPV
Abstract
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pDC Activation and Chronic Immune Activation in AIDS
pDC Activation and Chronic Immune Activation in AIDS
Abstract
HIV infection causes widespread persistent inflammation that leads to the progressive loss of function in the immune system and the onset of AIDS. The objective of this proposal is to investigate the interaction of HIV with the innate immune system and how this interaction impacts persistent inflammation during HIV infection. We will dissect the molecular events subsequent to activation of pDC by HIV and the impact that this sequence has on T cell function and differentiation.
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Development and Validation of a Cytokine Flow Cytometry Assay to Detect T Cell Immune Responses Against Pneumocystis Carinii
Development and Validation of a Cytokine Flow Cytometry Assay to Detect T Cell Immune Responses Against Pneumocystis Carinii
Abstract
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pDC Activation and Chronic Immune Activation in AIDS
pDC Activation and Chronic Immune Activation in AIDS
Abstract
HIV infection causes widespread persistent inflammation that leads to the progressive loss of function in the immune system and the onset of AIDS. The objective of this proposal is to investigate the interaction of HIV with the innate immune system and how this interaction impacts persistent inflammation during HIV infection. We will dissect the molecular events subsequent to activation of pDC by HIV and the impact that this sequence has on T cell function and differentiation.