Note: Beginning with Fall 2016, The Basic Science program has been combined into the Mentored Scientist Award mechanism - which now has three scientific priority areas for funding: Basic Science, Clinical/ Translational/ Epidemiological/ Behavioral, and Implementation Science.
Below are the awards made under the Basic Science program from 1994 to 2016.
58 Awards
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Activation of transcriptional elongation in HIV latently infected cells by SAHA
Activation of transcriptional elongation in HIV latently infected cells by SAHA
Abstract
Publications:
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Do Human Natural Killer Cells Acquire Immune Memory to Viral Infections?
Do Human Natural Killer Cells Acquire Immune Memory to Viral Infections?
Abstract
Natural killer (NK) cells have traditionally been considered members of the innate immune system. Recently, in a mouse model of cytomegalovirus, our lab has demonstrated that NK cells undergo clonal expansion during acute viral infection, the population contracts when virus is controlled, but remarkably infection induces a population of "memory" NK cells. These cells are long-lived, respond more robustly when re-challenged, and provide enhanced host protection against re-infection.
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Do Human Natural Killer Cells Acquire Immune Memory to Viral Infections?
Do Human Natural Killer Cells Acquire Immune Memory to Viral Infections?
Abstract
Natural killer (NK) cells have traditionally been considered members of the innate immune system. Recently, in a mouse model of cytomegalovirus, our lab has demonstrated that NK cells undergo clonal expansion during acute viral infection, the population contracts when virus is controlled, but remarkably infection induces a population of "memory" NK cells. These cells are long-lived, respond more robustly when re-challenged, and provide enhanced host protection against re-infection.
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Expanded Cellular Tropism of Human Immunodeficiency Virus 1 by a Trans-Receptor Mechanism
Expanded Cellular Tropism of Human Immunodeficiency Virus 1 by a Trans-Receptor Mechanism
Abstract
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Expanded Cellular Tropism of Human Immunodeficiency Virus 1 by a Trans-Receptor Mechanism
Expanded Cellular Tropism of Human Immunodeficiency Virus 1 by a Trans-Receptor Mechanism
Abstract
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Role of Double Modified Tat Protein in HIV-1 Transcription
Role of Double Modified Tat Protein in HIV-1 Transcription
Abstract
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Role of Double Modified Tat Protein in HIV-1 Transcription
Role of Double Modified Tat Protein in HIV-1 Transcription
Abstract
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Role of Chromatin Remodeling in HIV Transcriptional Regulation
Role of Chromatin Remodeling in HIV Transcriptional Regulation
Abstract
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Activation of the SIRT1 Deacetylase as a Therapeutic Concept in HIV-induced T Cell Hyperactivation
Activation of the SIRT1 Deacetylase as a Therapeutic Concept in HIV-induced T Cell Hyperactivation
Abstract
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The Kinetics of Primary Viremia in Macaques and Sooty Mangabeys Infected with Simian Immunodeficiency Virus
The Kinetics of Primary Viremia in Macaques and Sooty Mangabeys Infected with Simian Immunodeficiency Virus
Abstract
Publications: