Implementation science is an emerging field focused on closing the gap between efficacious interventions and real world practice. While the HIV research community has enthusiastically embraced the motivation for implementation science, there is far less consensus on the critical approaches to successful conduct of implementation science in the context of the HIV epidemic. Many methodological issues, which have perhaps been less emphasized in traditional clinical research, are particularly salient for knowledge about implementation. External validity is as important as internal validity. Context is a crucial. Engagement with diverse stakeholders is requisite. Managing flaws in data from electronic clinical records can render more representative data most useful. Implementation science, therefore, seeks not simply more research, but rather different research. If successful, this conversation will both use HIV research to advance implementation science more generally, as well as bring emerging perspectives to bear on the HIV epidemic.
Agenda
Implementation Science Study Design
Design and Practice of Implementation Science Trials
- Moderator: Margaret Handley, PhD, MPH
Slides:
Considerations in the Analysis Preference Sensitive Design
Slides
Trial Design and Analysis for Adaptive Interventions - Research Questions Closer to Practice
- Moderator: Margaret Handley, PhD, MPH
Slides
Set in Stone? Adaptive Trials
- Moderator: Margaret Handley, PhD, MPH
Slides
Moderated Discussion: Study Designs for Implementation Science
Panelists
- James Hargreaves, MSc, PhD
- Dave Glidden, PhD
- Maya Petersen, MD, PhD
- Mark van der Laan, PhD
Moderator
- Margaret A. Handley, PhD, MPH
Design of Implementation Strategies
Community Mobilization for the HIV Response
- Moderator: Maya Petersen, MD, PhD
Slides
Leveraging Social Networks to Improve Clinical Outcomes in HIV-Infected Youth in East Africa
- Moderator: Maya Petersen, MD, PhD
Slides
Task Shifting to the Mobile Phone: mHealth to Magnify the Human Resources for Health in Africa
- Moderator: Maya Petersen, MD, PhD
Livelihood Interventions: One Intervention, Many Effects
- Moderator: Maya Petersen, MD, PhD
Slides
Moderated Discussion: Design of Implementation Strategies
Panelists
- Sheri Lippman, PhD, MPH
- Lillian Brown, MD, PhD
-
Thomas Odeny, MBChB, MPH
-
Sheri Weiser, MD
Moderator
- Maya Petersen, MD, PhD
Evaluation
Leveraging Data for HIV Response: $100 Bills on the Ground
- Moderator: Diane Havlir, MD
Slides
Getting to Zero in San Francisco – The RAPID Initiative
Slides
Effect of Guidelines: An Application of Regression Discontinuity in Zambia
- Moderator: Diane Havlir, MD
Slides
Moderated Discussion: Evaluating What Happened
Panelists
- Eran Bendavid, MD
- Oliver Bacon, MD, MPH
-
Aaloke Mody, MD
Moderator
- Diane Havlir, MD
The Transport Framework
Impact: Epidemiologic Approaches to Implementation Science
Targeting PrEP: Transporting Subgroup Analyses of RCTs to Inform Implementation
- Moderator: Maria Glymour, ScD, MS
Slides
Bringing Context into Focus – Transportability Framework on the Effect of Housing
- Moderator: Maria Glymour, ScD, MS
Slides
Moderated Discussion: The Transport Framework
Panelists
- Daniel Westreich, PhD
- Megha L. Mehrotra, MPH, PhD(c)
-
Kara Rudolph, PhD, MHS, MPH
Moderator
- Maria Glymour, ScD, MS
