Lillian Brown

Assistant Professor, Division of HIV, ID and Global Medicine
Assistant Clinical Professor , School of Medicine

Email Lillian

1001 Potrero Ave
San Francisco, CA 94110

Visit CTSI Profile

Assistant Clinical Professor , School of Medicine

Biography

Career Overview

Dr. Brown is an Infectious Disease fellow in the Division of HIV, ID, and Global Medicine at the Zuckerberg San Francisco General Hospital and a Post-Doctoral Fellow in the Traineeships for AIDS Prevention Studies (TAPS). Her research examines the influence of social networks on engagement in HIV care with the goal of developing novel interventions to improve treatment outcomes in resource limited settings. She is currently a co-investigator on the ongoing SEARCH study in Uganda and Kenya and sees patients in the Positive Health Program at Ward 86 and in the Infectious Diseases clinic at Zuckerberg San Francisco General Hospital.

Spotlight: 2018 CFAR Excellence Award Recipient

When discussing her research, Lillian Brown underscores that traditional epidemiological models either ignore or adjust for the influence people have on each other – “but understanding how people are influenced by their social connections can lead to innovative and sustainable interventions by leveraging this social support.” Particularly important as an approach for studying youth, Brown emphasizes that they tends to lag behind adults in realizing the benefits of antiretroviral treatment.

“Stigma and lack of social support are also major contributors to their poor treatment outcomes,” she adds.

Brown’s interest in how social networks influence prevention and treatment interests unfolded as she went from an undergraduate career at Harvard to an MD and a PhD in epidemiology at the University of North Carolina.

With her latest and emerging findings, she is now looking to explore the social networks of HIV-infected youth in East Africa. Ultimately, this will enable her to design and implement more novel interventions to support their engagement in HIV care.

Raised in New England and now residing in the sunny Mission District of San Francisco with her husband and 8-month old son, Brown takes advantage of the Bay Area’s milder climate to spend her down time hiking, swimming, and exploring with her new family.

Displaying 1 - 25 of 35

  1. Spinelli MA, Brown LB, Glidden DV, Hunter K, Martin-Tuite P, Zheng J, Sera C, Havlir D, Buchbinder SP, Gandhi M. SARS-CoV-2 incidence, testing rates, and severe COVID-19 outcomes among people with and without HIV. AIDS. 2021 12 01; 35(15):2545-2547.
    http://www.ncbi.nlm.nih.gov/pubmed/34870933
  2. Shade SB, Osmand T, Kwarisiima D, Brown LB, Luo A, Mwebaza B, Mwesigye AR, Kwizera E, Imukeka H, Mwanga F, Ayieko J, Owaraganise A, Bukusi EA, Cohen CR, Charlebois ED, Black D, Clark TD, Petersen ML, Kamya MR, Havlir DV, Jain V. Costs of integrating hypertension care into HIV care in rural East African clinics. AIDS. 2021 05 01; 35(6):911-919.
    http://www.ncbi.nlm.nih.gov/pubmed/33821821
  3. Spinelli MA, Lynch KL, Yun C, Glidden DV, Peluso MJ, Henrich TJ, Gandhi M, Brown LB. SARS-CoV-2 seroprevalence, and IgG concentration and pseudovirus neutralising antibody titres after infection, compared by HIV status: a matched case-control observational study. Lancet HIV. 2021 06; 8(6):e334-e341.
    http://www.ncbi.nlm.nih.gov/pubmed/33933189
  4. Koss CA, Havlir DV, Ayieko J, Kwarisiima D, Kabami J, Chamie G, Atukunda M, Mwinike Y, Mwangwa F, Owaraganise A, Peng J, Olilo W, Snyman K, Awuonda B, Clark TD, Black D, Nugent J, Brown LB, Marquez C, Okochi H, Zhang K, Camlin CS, Jain V, Gandhi M, Cohen CR, Bukusi EA, Charlebois ED, Petersen ML, Kamya MR, Balzer LB. HIV incidence after pre-exposure prophylaxis initiation among women and men at elevated HIV risk: A population-based study in rural Kenya and Uganda. PLoS Med. 2021 02; 18(2):e1003492.
    http://www.ncbi.nlm.nih.gov/pubmed/33561143
  5. Brown LB, Spinelli MA, Gandhi M. The interplay between HIV and COVID-19: summary of the data and responses to date. Curr Opin HIV AIDS. 2021 01; 16(1):63-73.
    http://www.ncbi.nlm.nih.gov/pubmed/33186229
  6. Vivek Jain, Lillian B Brown, Carina Marquez, Luis Rubio, Natasha Spottiswoode, Bethlehem Churnet, Katherine Brooks, Mengyu Zhou, Timothy Muldoon, Carolyn Hendrickson, Adithya Cattamanchi, Antonio Gomez, Brian Haas, Edwin Charlebois, Annie Luetkemeyer, Annie Luetkemeyer, Monica Gandhi, Diane Havlir, Sumant Ranji, Lisa Gail Winston. 448. Disproportionate Burden of COVID-19 on Latinx Residents among Hospitalized Patients at San Francisco’s Public Health Hospital. Open Forum Infectious Diseases. 2020 Dec 31; 7(Suppl 1):s292-s292.
  7. Lillian B Brown, Lisa Gail Winston, Barbara Haller, Phong Pham, Beatrice Marcelo, Wendy Cheung, Kara Lynch, Vivek Jain. 496. Higher SARS-CoV-2 RT-PCR Cycle Threshold (Ct) Values Associated with Longer Symptom Duration Among Patients Hospitalized with COVID-19. Open Forum Infectious Diseases. 2020 Dec 31; 7(Suppl 1):s314-s314.
  8. Vivek Jain, Lillian B Brown, Carina Marquez, Luis Rubio, Natasha Spottiswoode, Bethlehem Churnet, Katherine Brooks, Mengyu Zhou, Timothy Muldoon, Carolyn Hendrickson, Adithya Cattamanchi, Antonio Gomez, Brian Haas, Edwin Charlebois, Annie Luetkemeyer, Annie Luetkemeyer, Monica Gandhi, Diane Havlir, Sumant Ranji, Lisa Gail Winston. 448. Disproportionate Burden of COVID-19 on Latinx Residents among Hospitalized Patients at San Francisco’s Public Health Hospital. Open Forum Infectious Diseases. 2020 Dec 31; 7(Suppl 1):s292-s292.
    http://www.ncbi.nlm.nih.gov/pubmed/32511538
  9. Lillian B Brown, Lisa Gail Winston, Barbara Haller, Phong Pham, Beatrice Marcelo, Wendy Cheung, Kara Lynch, Vivek Jain. 496. Higher SARS-CoV-2 RT-PCR Cycle Threshold (Ct) Values Associated with Longer Symptom Duration Among Patients Hospitalized with COVID-19. Open Forum Infectious Diseases. 2020 Dec 31; 7(Suppl 1):s314-s314.
    http://www.ncbi.nlm.nih.gov/pubmed/32087152
  10. Vanderburg S, Alipanah N, Crowder R, Yoon C, Wang R, Thakur N, Slown K, Shete PB, Rofael M, Metcalfe JZ, Merrifield C, Marquez C, Malcolm K, Lipnick M, Jain V, Gomez A, Burns G, Brown LB, Berger C, Auyeung V, Cattamanchi A, Hendrickson CM. Management and Outcomes of Critically-Ill Patients with COVID-19 Pneumonia at a Safety-net Hospital in San Francisco, a Region with Early Public Health Interventions: A Case Series. medRxiv. 2020 May 29.
    http://www.ncbi.nlm.nih.gov/pubmed/31809357
  11. Koss CA, Charlebois ED, Ayieko J, Kwarisiima D, Kabami J, Balzer LB, Atukunda M, Mwangwa F, Peng J, Mwinike Y, Owaraganise A, Chamie G, Jain V, Sang N, Olilo W, Brown LB, Marquez C, Zhang K, Ruel TD, Camlin CS, Rooney JF, Black D, Clark TD, Gandhi M, Cohen CR, Bukusi EA, Petersen ML, Kamya MR, Havlir DV, SEARCH Collaboration . Uptake, engagement, and adherence to pre-exposure prophylaxis offered after population HIV testing in rural Kenya and Uganda: 72-week interim analysis of observational data from the SEARCH study. Lancet HIV. 2020 04; 7(4):e249-e261.
    http://www.ncbi.nlm.nih.gov/pubmed/31060545
  12. Ayieko J, Petersen ML, Charlebois ED, Brown LB, Clark TD, Kwarisiima D, Kamya MR, Cohen CR, Bukusi EA, Havlir DV, Van Rie A. A Patient-Centered Multicomponent Strategy for Accelerated Linkage to Care Following Community-Wide HIV Testing in Rural Uganda and Kenya. J Acquir Immune Defic Syndr. 2019 Apr 01; 80(4):414-422.
    http://www.ncbi.nlm.nih.gov/pubmed/30807481
  13. Brown LB, Getahun M, Ayieko J, Kwarisiima D, Owaraganise A, Atukunda M, Olilo W, Clark T, Bukusi EA, Cohen CR, Kamya MR, Petersen ML, Charlebois ED, Havlir DV, Camlin CS. Factors predictive of successful retention in care among HIV-infected men in a universal test-and-treat setting in Uganda and Kenya: A mixed methods analysis. PLoS One. 2019; 14(1):e0210126.
    http://www.ncbi.nlm.nih.gov/pubmed/30673744
  14. Lin J, Hecht J, Plenty AH, Siedle-Khan B, Zamudio-Haas S, Ayala A, Charlebois ED.. Alcohol Consumption and Management Strategies Among Gay Bar Patrons in San Francisco and Oakland, CA. Contemporary Drug Problems. 2019; 46(1):22-40.
    http://www.ncbi.nlm.nih.gov/pubmed/30585857
  15. Havlir, D.V., Balzer, L.B., Charlebois, E.D., Clark, T.D., Kwarisiima, D., Ayieko, J., Kabami, J., Sang, N., Liegler, T., Chamie, G., Camlin, C.S., Jain, V., Kadede, K., Atukunda, M., Ruel, T., Shade, S.B., Ssemmondo, E., Byonanebye, D.M., Mwangwa, F., Owaraganise, A., Olilo, W., Black, D., Snyman, K., Burger, R., Getahun, M., Achando, J., Awuonda, B., Nakato, H., Kironde, J., Okiror, S., Thirumurthy, H., Koss, C., Brown, L., Marquez, C., Schwab, J., Lavoy, G., Plenty, A., Wafula, E.M., Omanya, P., Chen, Y., Rooney, J.F., Bacon, M., van der Laan, M., Cohen, C.R., Bukusi, E., Kamya, M.R., and Petersen, M. . Trial of HIV test and treat via a community health model in rural Africa. New Engl J Med. 2019; In Press.
    http://www.ncbi.nlm.nih.gov/pubmed/30134294
  16. Koss CA, Ayieko J, Mwangwa F, Owaraganise A, Kwarisiima D, Balzer LB, Plenty A, Sang N, Kabami J, Ruel TD, Black D, Camlin CS, Cohen CR, Bukusi EA, Clark TD, Charlebois ED, Petersen ML, Kamya MR, Havlir DV. Early Adopters of Human Immunodeficiency Virus Preexposure Prophylaxis in a Population-based Combination Prevention Study in Rural Kenya and Uganda. Clin Infect Dis. 2018 Nov 28; 67(12):1853-1860.
    http://www.ncbi.nlm.nih.gov/pubmed/30161172
  17. Shade SB, Osmand T, Luo A, Aine R, Assurah E, Mwebaza B, Mwai D, Owaraganise A, Mwangwa F, Ayieko J, Black D, Brown LB, Clark TD, Kwarisiima D, Thirumurthy H, Cohen CR, Bukusi EA, Charlebois ED, Balzer L, Kamya MR, Petersen ML, Havlir DV, Jain V. Costs of streamlined HIV care delivery in rural Ugandan and Kenyan clinics in the SEARCH Studys. AIDS. 2018 Sep 24; 32(15):2179-2188.
    http://www.ncbi.nlm.nih.gov/pubmed/28394821
  18. Koss CA, Natureeba P, Kwarisiima D, Ogena M, Clark TD, Olwoch P, Cohan D, Okiring J, Charlebois ED, Kamya MR, Havlir DV. Viral Suppression and Retention in Care up to 5 Years After Initiation of Lifelong ART During Pregnancy (Option B+) in Rural Uganda. J Acquir Immune Defic Syndr. 2017 Mar 01; 74(3):279-284.
    http://www.ncbi.nlm.nih.gov/pubmed/27603290
  19. Brown L, Langelier C, Reid MJ, Rutishauser RL, Strnad L. Antimicrobial Resistance: A Call to Action! Clin Infect Dis. 2017 01 01; 64(1):106-107.
    http://www.ncbi.nlm.nih.gov/pubmed/27794024
  20. Kamanga G, Brown L, Jawati P, Chiwanda D, Nyirenda N. Maximizing HIV partner notification opportunities for index patients and their sexual partners in Malawi. Malawi Med J. 2015 Dec; 27(4):140-4.
    http://www.ncbi.nlm.nih.gov/pubmed/26955435
  21. Shaboltas AV, Skochilov RV, Brown LB, Elharrar VN, Kozlov AP, Hoffman IF. The feasibility of an intensive case management program for injection drug users on antiretroviral therapy in St. Petersburg, Russia. Harm Reduct J. 2013 Sep 05; 10:15.
    http://www.ncbi.nlm.nih.gov/pubmed/24006958
  22. Rutstein SE, Brown LB, Biddle AK, Wheeler SB, Kamanga G, Mmodzi P, Nyirenda N, Mofolo I, Rosenberg NE, Hoffman IF, Miller WC. Cost-effectiveness of provider-based HIV partner notification in urban Malawi. Health Policy Plan. 2014 Jan; 29(1):115-26.
    http://www.ncbi.nlm.nih.gov/pubmed/23325584
  23. Nora E. Rosenberg, Gift Kamanga, Sam Phiri, Dominic Nsona, Audrey Pettifor, Sarah E. Rutstein, Deborah Kamwendo, Irving F. Hoffman, Maria Keating, Lillian B. Brown, Beatrice Ndalama, Susan A. Fiscus, Seth Congdon, Myron S. Cohen, William C. Miller. Point-of-Care Diagnostics for Acute HIV Infection: An Important Public Health Priority. The Journal of Infectious Diseases. 2012 Dec 15; 206(12):1949-1950.
  24. Brown LB, Miller WC, Kamanga G, Kaufman JS, Pettifor A, Dominik RC, Nyirenda N, Mmodzi P, Mapanje C, Martinson F, Cohen MS, Hoffman IF. Predicting partner HIV testing and counseling following a partner notification intervention. AIDS Behav. 2012 Jul; 16(5):1148-55.
    http://www.ncbi.nlm.nih.gov/pubmed/22120879
  25. Rosenberg NE, Kamanga G, Phiri S, Nsona D, Pettifor A, Rutstein SE, Kamwendo D, Hoffman IF, Keating M, Brown LB, Ndalama B, Fiscus SA, Congdon S, Cohen MS, Miller WC. Detection of acute HIV infection: a field evaluation of the determine® HIV-1/2 Ag/Ab combo test. J Infect Dis. 2012 Feb 15; 205(4):528-34.
    http://www.ncbi.nlm.nih.gov/pubmed/22207651