UCSF COVID-19 Rapid Response Pilot Grant

3 Awards

Contacts
  • The role of tenofovir-based HIV treatment and prevention on COVID-19 prevalence and outcomes

    The role of tenofovir-based HIV treatment and prevention on COVID-19 prevalence and outcomes

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    Abstract

    Little is known regarding risk of COVID-19 in people with HIV (PLWH) and how tenofovir (TFV), an antiretroviral (ART) used for HIV treatment and prevention, may confer protection against COVID-19. This research leverages public health data of PLWH and COVID-19 in San Francisco to determine if HIV itself or ART alters risk of COVID-19 infection.

  • Epidemiology, Health Disparities, Public Health HIV Care Engagement and Retention in Care

    Epidemiology, Health Disparities, Public Health HIV Care Engagement and Retention in Care

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    Abstract

    People living with HIV with criminal justice involvement are particularly vulnerable population, with poor pre-release and post-release HIV care cascade outcomes and diverse non-HIV social services engagement. Hence, they are likely to be disproportionately impacted by shelter-in-place orders, reduced incarceration rates and criminal justice reform.

  • Virologic and immunologic correlates of SARS-CoV-2 infection in people living with HIV

    Virologic and immunologic correlates of SARS-CoV-2 infection in people living with HIV

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    Abstract

    Little is known about the short- and long-term impact of SARS-CoV-2 infection in people living with HIV. In Aim 1, we will characterize a clinical cohort of People with HIV with PCR-confirmed SARS-CoV-2 through a collaboration with colleagues in New York City. In Aim 2, we will characterize the SARS-CoV-2-specific T cell responses in HIV positive and -negative individuals in the UCSF SCOPE-COVID and LIINC cohorts to determine how these differ in People with HIV. In Aim 3, we will measure the effects of COVID-19 on HIV reservoir dynamics.