Ruth Greenblatt, MD

Headshot of Ruth Greenblatt
User Profile Photo

Ruth Greenblatt, MD

User Profile Name
Emeritus CFAR Mentor
Professor Emeritus, School of Pharmacy
User Profile Title
User Profile Email
Visit CTSI Profile

Biography

I am an Infectious Diseases trained Internist based in the Department of Clinical Pharmacy, in the UCSF School of Pharmacy. My research is focused on HIV infection in women, particularly the effects of gonadal aging and pharmacology. My group developed novel methods for assessing exposure to antiretroviral drugs using small samples of hair. I am one of three Principal Investigators of the Northern California site of the Women's Interagency HIV Study, which is the largest NIH-supported study of HIV among women, and one of the most diverse NIH-funded cohort studies. I am the founder of the UCSF WIHS consortium and the UCSF Women's HIV Practice. Within the School of Pharmacy, I am the Vice Chair for Research of the Department of Clinical Pharmacy (Lisa Kroon, PharmD is the Chair). I previously chaired the UCSF School of Pharmacy Faculty Council, and I am currently Vice Chair of the UCSF Academic Senate. With the School of Pharmacy Dean, B. Joseph Guglielmo, and Monica Gandhi, MD, I co-lead the UCSF Bridging Interdisciplinary Research Careers in Women's Health K-12 program for early career clinical scientists focused on Women's Health. I co-founded, with James Kahn, the UCSF/Gladstone Center for AIDS Research Mentoring Program.
CTSI Profile Bio

Displaying 26 - 50 of 143

  1. Nabi R, Moldoveanu Z, Wei Q, Golub ET, Durkin HG, Greenblatt RM, Herold BC, Nowicki MJ, Kassaye S, Cho MW, Pinter A, Landay AL, Mestecky J, Kozlowski PA. Differences in serum IgA responses to HIV-1 gp41 in elite controllers compared to viral suppressors on highly active antiretroviral therapy. PLoS One. 2017; 12(7):e0180245.
    http://www.ncbi.nlm.nih.gov/pubmed/28671952
  2. Jacobs ES, Keating SM, Abdel-Mohsen M, Gibb SL, Heitman JW, Inglis HC, Martin JN, Zhang J, Kaidarova Z, Deng X, Wu S, Anastos K, Crystal H, Villacres MC, Young M, Greenblatt RM, Landay AL, Gange SJ, Deeks SG, Golub ET, Pillai SK, Norris PJ. Cytokines Elevated in HIV Elite Controllers Reduce HIV Replication In Vitro and Modulate HIV Restriction Factor Expression. J Virol. 2017 03 15; 91(6).
    http://www.ncbi.nlm.nih.gov/pubmed/28053103
  3. Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. PLoS Pathog. 2017 02; 13(2):e1006163.
    http://www.ncbi.nlm.nih.gov/pubmed/28207890
  4. Massad LS, Evans CT, Kang R, Hotton A, Greenblatt R, Minkoff H, Murphy K, Colie C, Weber KM. Correlates of Bacterial Vaginosis Over Long-Term Follow-Up: Impact of HIV Infection. AIDS Res Hum Retroviruses. 2017 05; 33(5):432-439.
    http://www.ncbi.nlm.nih.gov/pubmed/27841674
  5. Shanmugasundaram U, Hilton JF, Critchfield JW, Greenblatt RM, Giudice LC, Averbach S, Seidman D, Shacklett BL, Smith-McCune K. Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium. Am J Reprod Immunol. 2016 08; 76(2):137-48.
    http://www.ncbi.nlm.nih.gov/pubmed/27401588
  6. Desai SN, Dodge JL, Landay AL, Glesby MJ, Latham PS, Villacres MC, French AL, Gange SJ, Greenblatt RM, Peters MG. Hepatic fibrosis and immune phenotype vary by HCV viremia in HCV/HIV co-infected subjects: A Women's interagency HIV study. Medicine (Baltimore). 2016 Aug; 95(33):e4483.
    http://www.ncbi.nlm.nih.gov/pubmed/27537569
  7. Scherzer R, Greenblatt RM, Merhi ZO, Kassaye S, Lambert-Messerlian G, Maki PM, Murphy K, Karim R, Bacchetti P. Use of antimüllerian hormone to predict the menopausal transition in HIV-infected women. Am J Obstet Gynecol. 2017 Jan; 216(1):46.e1-46.e11.
    http://www.ncbi.nlm.nih.gov/pubmed/27473002
  8. Baxi SM, Scherzer R, Greenblatt RM, Minkoff H, Sharma A, Cohen M, Young MA, Abraham AG, Shlipak MG. Higher tenofovir exposure is associated with longitudinal declines in kidney function in women living with HIV. AIDS. 2016 Feb 20; 30(4):609-18.
    http://www.ncbi.nlm.nih.gov/pubmed/26558723
  9. Norris PJ, Zhang J, Worlock A, Nair SV, Anastos K, Minkoff HL, Villacres MC, Young M, Greenblatt RM, Desai S, Landay AL, Gange SJ, Nugent CT, Golub ET, Keating SM. Systemic Cytokine Levels Do Not Predict CD4(+) T-Cell Recovery After Suppressive Combination Antiretroviral Therapy in Chronic Human Immunodeficiency Virus Infection. Open Forum Infect Dis. 2016 Jan; 3(1):ofw025.
    http://www.ncbi.nlm.nih.gov/pubmed/26966697
  10. Cribbs SK, Uppal K, Li S, Jones DP, Huang L, Tipton L, Fitch A, Greenblatt RM, Kingsley L, Guidot DM, Ghedin E, Morris A. Correlation of the lung microbiota with metabolic profiles in bronchoalveolar lavage fluid in HIV infection. Microbiome. 2016 Jan 20; 4:3.
    http://www.ncbi.nlm.nih.gov/pubmed/26792212
  11. Oh SS, Galanter J, Thakur N, Pino-Yanes M, Barcelo NE, White MJ, de Bruin DM, Greenblatt RM, Bibbins-Domingo K, Wu AH, Borrell LN, Gunter C, Powe NR, Burchard EG. Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled. PLoS Med. 2015 Dec; 12(12):e1001918.
    http://www.ncbi.nlm.nih.gov/pubmed/26671224
  12. Cates JE, Westreich D, Edmonds A, Wright RL, Minkoff H, Colie C, Greenblatt RM, Cejtin HE, Karim R, Haddad LB, Kempf MC, Golub ET, Adimora AA. The Effects of Viral Load Burden on Pregnancy Loss among HIV-Infected Women in the United States. Infect Dis Obstet Gynecol. 2015; 2015:362357.
    http://www.ncbi.nlm.nih.gov/pubmed/26582966
  13. Lang Kuhs KA, Kuniholm MH, Pfeiffer RM, Chen S, Desai S, Edlin BR, Peters MG, Plankey M, Sharp GB, Strickler HD, Villacres MC, Quinn TC, Gange SJ, Prokunina-Olsson L, Greenblatt RM, O'Brien TR. Interferon Lambda 4 Genotype Is Not Associated with Recurrence of Oral or Genital Herpes. PLoS One. 2015; 10(10):e0138827.
    http://www.ncbi.nlm.nih.gov/pubmed/26431156
  14. Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC. Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. PLoS One. 2015; 10(7):e0129769.
    http://www.ncbi.nlm.nih.gov/pubmed/26177352
  15. Aziz M, Mahmood F, Mata M, Durkin HG, Liu C, Greenblatt RM, Nowicki M, Golub ET, Anastos K, French AL, Baum LL. Development of IgG Mediated Antibody Dependent Cell-mediated Cytotoxicity (ADCC) in the Serum and Genital Mucosa of HIV Seroconverters. J AIDS Clin Res. 2015 Jul; 6(7).
    http://www.ncbi.nlm.nih.gov/pubmed/26798561
  16. Baxi SM, Greenblatt RM, Bacchetti P, Jin C, French AL, Keller MJ, Augenbraun MH, Gange SJ, Liu C, Mack WJ, Gandhi M. Nevirapine Concentration in Hair Samples Is a Strong Predictor of Virologic Suppression in a Prospective Cohort of HIV-Infected Patients. PLoS One. 2015; 10(6):e0129100.
    http://www.ncbi.nlm.nih.gov/pubmed/26053176
  17. Sciaranghella G, Wang C, Hu H, Anastos K, Merhi Z, Nowicki M, Stanczyk FZ, Greenblatt RM, Cohen M, Golub ET, Watts DH, Alter G, Young MA, Tsibris AM. CCR5 Expression Levels in HIV-Uninfected Women Receiving Hormonal Contraception. J Infect Dis. 2015 Nov 01; 212(9):1397-401.
    http://www.ncbi.nlm.nih.gov/pubmed/25895986
  18. Cui L, Lucht L, Tipton L, Rogers MB, Fitch A, Kessinger C, Camp D, Kingsley L, Leo N, Greenblatt RM, Fong S, Stone S, Dermand JC, Kleerup EC, Huang L, Morris A, Ghedin E. Topographic diversity of the respiratory tract mycobiome and alteration in HIV and lung disease. Am J Respir Crit Care Med. 2015 Apr 15; 191(8):932-42.
    http://www.ncbi.nlm.nih.gov/pubmed/25603113
  19. Goldfien GA, Barragan F, Chen J, Takeda M, Irwin JC, Perry J, Greenblatt RM, Smith-McCune KK, Giudice LC. Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix. Reprod Sci. 2015 Jul; 22(7):814-28.
    http://www.ncbi.nlm.nih.gov/pubmed/25634912
  20. Simonetti JA, Gingo MR, Kingsley L, Kessinger C, Lucht L, Balasubramani G, Leader JK, Huang L, Greenblatt RM, Dermand J, Kleerup EC, Morris A. Pulmonary Function in HIV-Infected Recreational Drug Users in the Era of Anti-Retroviral Therapy. J AIDS Clin Res. 2014 Nov; 5(11).
    http://www.ncbi.nlm.nih.gov/pubmed/25664201
  21. Scherzer R, Bacchetti P, Messerlian G, Goderre J, Maki PM, Seifer DB, Anastos K, Karim R, Greenblatt RM. Impact of CD4+ lymphocytes and HIV infection on Anti-Müllerian Hormone levels in a large cohort of HIV-infected and HIV-uninfected women. Am J Reprod Immunol. 2015 Mar; 73(3):273-84.
    http://www.ncbi.nlm.nih.gov/pubmed/25339186
  22. Yalamanchi S, Dobs A, Greenblatt RM. Gonadal function and reproductive health in women with human immunodeficiency virus infection. Endocrinol Metab Clin North Am. 2014 Sep; 43(3):731-41.
    http://www.ncbi.nlm.nih.gov/pubmed/25169564
  23. Rubin LH, Sundermann EE, Cook JA, Martin EM, Golub ET, Weber KM, Cohen MH, Crystal H, Cederbaum JA, Anastos K, Young M, Greenblatt RM, Maki PM. Investigation of menopausal stage and symptoms on cognition in human immunodeficiency virus-infected women. Menopause. 2014 Sep; 21(9):997-1006.
    http://www.ncbi.nlm.nih.gov/pubmed/24496085
  24. Gingo MR, Balasubramani GK, Rice TB, Kingsley L, Kleerup EC, Detels R, Seaberg EC, Greenblatt RM, Holman S, Huang L, Sutton SH, Bertolet M, Morris A. Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts. BMC Pulm Med. 2014 Apr 30; 14:75.
    http://www.ncbi.nlm.nih.gov/pubmed/24884738
  25. Landay A, Golub ET, Desai S, Zhang J, Winkelman V, Anastos K, Durkin H, Young M, Villacres MC, Greenblatt RM, Norris PJ, Busch MP. HIV RNA levels in plasma and cervical-vaginal lavage fluid in elite controllers and HAART recipients. AIDS. 2014 Mar 13; 28(5):739-43.
    http://www.ncbi.nlm.nih.gov/pubmed/24326356