Ruth Greenblatt, MD

Headshot of Ruth Greenblatt
User Profile Photo

Ruth Greenblatt, MD

User Profile Name
Emeritus CFAR Mentor
Professor Emeritus, School of Pharmacy
User Profile Title
User Profile Email
Visit CTSI Profile

Biography

I am an Infectious Diseases trained Internist based in the Department of Clinical Pharmacy, in the UCSF School of Pharmacy. My research is focused on HIV infection in women, particularly the effects of gonadal aging and pharmacology. My group developed novel methods for assessing exposure to antiretroviral drugs using small samples of hair. I am one of three Principal Investigators of the Northern California site of the Women's Interagency HIV Study, which is the largest NIH-supported study of HIV among women, and one of the most diverse NIH-funded cohort studies. I am the founder of the UCSF WIHS consortium and the UCSF Women's HIV Practice. Within the School of Pharmacy, I am the Vice Chair for Research of the Department of Clinical Pharmacy (Lisa Kroon, PharmD is the Chair). I previously chaired the UCSF School of Pharmacy Faculty Council, and I am currently Vice Chair of the UCSF Academic Senate. With the School of Pharmacy Dean, B. Joseph Guglielmo, and Monica Gandhi, MD, I co-lead the UCSF Bridging Interdisciplinary Research Careers in Women's Health K-12 program for early career clinical scientists focused on Women's Health. I co-founded, with James Kahn, the UCSF/Gladstone Center for AIDS Research Mentoring Program.
CTSI Profile Bio

Displaying 51 - 75 of 143

  1. Liu AY, Yang Q, Huang Y, Bacchetti P, Anderson PL, Jin C, Goggin K, Stojanovski K, Grant R, Buchbinder SP, Greenblatt RM, Gandhi M. Strong relationship between oral dose and tenofovir hair levels in a randomized trial: hair as a potential adherence measure for pre-exposure prophylaxis (PrEP). PLoS One. 2014; 9(1):e83736.
    http://www.ncbi.nlm.nih.gov/pubmed/24421901
  2. Baxi SM, Greenblatt RM, Bacchetti P, Scherzer R, Minkoff H, Huang Y, Anastos K, Cohen M, Gange SJ, Young M, Shlipak MG, Gandhi M. Common clinical conditions - age, low BMI, ritonavir use, mild renal impairment - affect tenofovir pharmacokinetics in a large cohort of HIV-infected women. AIDS. 2014 Jan 02; 28(1):59-66.
    http://www.ncbi.nlm.nih.gov/pubmed/24275255
  3. Shanmugasundaram U, Critchfield JW, Pannell J, Perry J, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL. Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women. Am J Reprod Immunol. 2014 Feb; 71(2):95-108.
    http://www.ncbi.nlm.nih.gov/pubmed/24313954
  4. Fitzpatrick ME, Gingo MR, Kessinger C, Lucht L, Kleerup E, Greenblatt RM, Claman D, Ponath C, Fong S, Huang L, Morris A. HIV infection is associated with diffusing capacity impairment in women. J Acquir Immune Defic Syndr. 2013 Nov 01; 64(3):284-8.
    http://www.ncbi.nlm.nih.gov/pubmed/23979000
  5. Hessol NA, Holly EA, Efird JT, Minkoff H, Weber KM, Darragh TM, Burk RD, Strickler HD, Greenblatt RM, Palefsky JM. Concomitant anal and cervical human papillomavirusV infections and intraepithelial neoplasia in HIV-infected and uninfected women. AIDS. 2013 Jul 17; 27(11):1743-51.
    http://www.ncbi.nlm.nih.gov/pubmed/23803793
  6. Gwaza L, Aweeka F, Greenblatt R, Lizak P, Huang L, Guglielmo BJ. Co-administration of a commonly used Zimbabwean herbal treatment (African potato) does not alter the pharmacokinetics of lopinavir/ritonavir. Int J Infect Dis. 2013 Oct; 17(10):e857-61.
    http://www.ncbi.nlm.nih.gov/pubmed/23587599
  7. Gingo MR, Balasubramani GK, Kingsley L, Rinaldo CR, Alden CB, Detels R, Greenblatt RM, Hessol NA, Holman S, Huang L, Kleerup EC, Phair J, Sutton SH, Seaberg EC, Margolick JB, Wisniewski SR, Morris A. The impact of HAART on the respiratory complications of HIV infection: longitudinal trends in the MACS and WIHS cohorts. PLoS One. 2013; 8(3):e58812.
    http://www.ncbi.nlm.nih.gov/pubmed/23554932
  8. Karim R, Mack WJ, Kono N, Tien PC, Anastos K, Lazar J, Young M, Cohen M, Golub E, Greenblatt RM, Kaplan RC, Hodis HN. Gonadotropin and sex steroid levels in HIV-infected premenopausal women and their association with subclinical atherosclerosis in HIV-infected and -uninfected women in the women's interagency HIV study (WIHS). J Clin Endocrinol Metab. 2013 Apr; 98(4):E610-8.
    http://www.ncbi.nlm.nih.gov/pubmed/23418313
  9. D'souza G, Matson PA, Grady CD, Nahvi S, Merenstein D, Weber KM, Greenblatt R, Burian P, Wilson TE. Medicinal and recreational marijuana use among HIV-infected women in the Women's Interagency HIV Study (WIHS) cohort, 1994-2010. J Acquir Immune Defic Syndr. 2012 Dec 15; 61(5):618-26.
    http://www.ncbi.nlm.nih.gov/pubmed/23011399
  10. Maki PM, Rubin LH, Cohen M, Golub ET, Greenblatt RM, Young M, Schwartz RM, Anastos K, Cook JA. Depressive symptoms are increased in the early perimenopausal stage in ethnically diverse human immunodeficiency virus-infected and human immunodeficiency virus-uninfected women. Menopause. 2012 Nov; 19(11):1215-23.
    http://www.ncbi.nlm.nih.gov/pubmed/22872013
  11. Frasco MA, Mack WJ, Van Den Berg D, Aouizerat BE, Anastos K, Cohen M, De Hovitz J, Golub ET, Greenblatt RM, Liu C, Conti DV, Pearce CL. Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine. AIDS. 2012 Oct 23; 26(16):2097-106.
    http://www.ncbi.nlm.nih.gov/pubmed/22951632
  12. Gandhi M, Greenblatt RM, Bacchetti P, Jin C, Huang Y, Anastos K, Cohen M, Dehovitz JA, Sharp GB, Gange SJ, Liu C, Hanson SC, Aouizerat B. A single-nucleotide polymorphism in CYP2B6 leads to >3-fold increases in efavirenz concentrations in plasma and hair among HIV-infected women. J Infect Dis. 2012 Nov; 206(9):1453-61.
    http://www.ncbi.nlm.nih.gov/pubmed/22927450
  13. Cocohoba JM, Althoff KN, Cohen M, Hu H, Cunningham CO, Sharma A, Greenblatt RM. Pharmacist counseling in a cohort of women with HIV and women at risk for HIV. Patient Prefer Adherence. 2012; 6:457-63.
    http://www.ncbi.nlm.nih.gov/pubmed/22791983
  14. Villacres MC, Kono N, Mack WJ, Nowicki MJ, Anastos K, Augenbraun M, Liu C, Landay A, Greenblatt RM, Gange SJ, Levine AM. Interleukin 10 responses are associated with sustained CD4 T-cell counts in treated HIV infection. J Infect Dis. 2012 Sep 01; 206(5):780-9.
    http://www.ncbi.nlm.nih.gov/pubmed/22693231
  15. Homans J, Christensen S, Stiller T, Wang CH, Mack W, Anastos K, Minkoff H, Young M, Greenblatt R, Cohen M, Strickler H, Karim R, Spencer LY, Operskalski E, Frederick T, Kovacs A. Permissive and protective factors associated with presence, level, and longitudinal pattern of cervicovaginal HIV shedding. J Acquir Immune Defic Syndr. 2012 May 01; 60(1):99-110.
    http://www.ncbi.nlm.nih.gov/pubmed/22517416
  16. Weinberg A, Allshouse AA, Mawhinney S, Canniff J, Benning L, Wentz EL, Minkoff H, Young M, Nowicki M, Greenblatt R, Cohen MH, Golub ET. Responses to hepatitis A virus vaccine in HIV-infected women: effect of hormonal contraceptives and HIV disease characteristics. J Acquir Immune Defic Syndr. 2012 May 01; 60(1):e15-8.
    http://www.ncbi.nlm.nih.gov/pubmed/22517417
  17. Merhi ZO, Seifer DB, Weedon J, Adeyemi O, Holman S, Anastos K, Golub ET, Young M, Karim R, Greenblatt R, Minkoff H. Circulating vitamin D correlates with serum antimüllerian hormone levels in late-reproductive-aged women: Women's Interagency HIV Study. Fertil Steril. 2012 Jul; 98(1):228-34.
    http://www.ncbi.nlm.nih.gov/pubmed/22494925
  18. Saberi P, Dong BJ, Johnson MO, Greenblatt RM, Cocohoba JM. The impact of HIV clinical pharmacists on HIV treatment outcomes: a systematic review. Patient Prefer Adherence. 2012; 6:297-322.
    http://www.ncbi.nlm.nih.gov/pubmed/22536064
  19. Massad LS, Xie X, Greenblatt RM, Minkoff H, Sanchez-Keeland L, Watts DH, Wright RL, D'Souza G, Merenstein D, Strickler H. Effect of human immunodeficiency virus infection on the prevalence and incidence of vaginal intraepithelial neoplasia. Obstet Gynecol. 2012 Mar; 119(3):582-9.
    http://www.ncbi.nlm.nih.gov/pubmed/22353957
  20. Greenblatt RM. Priority issues concerning HIV infection among women. Womens Health Issues. 2011 Nov; 21(6 Suppl):S266-71.
    http://www.ncbi.nlm.nih.gov/pubmed/22055678
  21. Keating SM, Golub ET, Nowicki M, Young M, Anastos K, Crystal H, Cohen MH, Zhang J, Greenblatt RM, Desai S, Wu S, Landay AL, Gange SJ, Norris PJ. The effect of HIV infection and HAART on inflammatory biomarkers in a population-based cohort of women. AIDS. 2011 Sep 24; 25(15):1823-32.
    http://www.ncbi.nlm.nih.gov/pubmed/21572306
  22. Bordón J, Plankey MW, Young M, Greenblatt RM, Villacres MC, French AL, Zhang J, Brock G, Appana S, Herold B, Durkin H, Golub JE, Fernandez-Botran R. Lower levels of interleukin-12 precede the development of tuberculosis among HIV-infected women. Cytokine. 2011 Nov; 56(2):325-31.
    http://www.ncbi.nlm.nih.gov/pubmed/21880503
  23. Manly JJ, Smith C, Crystal HA, Richardson J, Golub ET, Greenblatt R, Robison E, Martin EM, Young M. Relationship of ethnicity, age, education, and reading level to speed and executive function among HIV+ and HIV- women: the Women's Interagency HIV Study (WIHS) Neurocognitive Substudy. J Clin Exp Neuropsychol. 2011 Oct; 33(8):853-63.
    http://www.ncbi.nlm.nih.gov/pubmed/21950512
  24. Kuniholm MH, Gao X, Xue X, Kovacs A, Anastos K, Marti D, Greenblatt RM, Cohen MH, Minkoff H, Gange SJ, Fazzari M, Young MA, Strickler HD, Carrington M. Human leukocyte antigen genotype and risk of HIV disease progression before and after initiation of antiretroviral therapy. J Virol. 2011 Oct; 85(20):10826-33.
    http://www.ncbi.nlm.nih.gov/pubmed/21849458
  25. Huang Y, Yang Q, Yoon K, Lei Y, Shi R, Gee W, Lin ET, Greenblatt RM, Gandhi M. Microanalysis of the antiretroviral nevirapine in human hair from HIV-infected patients by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2011 Oct; 401(6):1923-33.
    http://www.ncbi.nlm.nih.gov/pubmed/21847531