Ruth Greenblatt, MD
Emeritus CFAR Mentor
Professor Emeritus, School of Pharmacy
Email: ruth.greenblatt@ucsf.edu
Biography
I am an Infectious Diseases trained Internist based in the Department of Clinical Pharmacy, in the UCSF School of Pharmacy. My research is focused on HIV infection in women, particularly the effects of gonadal aging and pharmacology. My group developed novel methods for assessing exposure to antiretroviral drugs using small samples of hair. I am one of three Principal Investigators of the Northern California site of the Women's Interagency HIV Study, which is the largest NIH-supported study of HIV among women, and one of the most diverse NIH-funded cohort studies. I am the founder of the UCSF WIHS consortium and the UCSF Women's HIV Practice.
Within the School of Pharmacy, I am the Vice Chair for Research of the Department of Clinical Pharmacy (Lisa Kroon, PharmD is the Chair). I previously chaired the UCSF School of Pharmacy Faculty Council, and I am currently Vice Chair of the UCSF Academic Senate.
With the School of Pharmacy Dean, B. Joseph Guglielmo, and Monica Gandhi, MD, I co-lead the UCSF Bridging Interdisciplinary Research Careers in Women's Health K-12 program for early career clinical scientists focused on Women's Health. I co-founded, with James Kahn, the UCSF/Gladstone Center for AIDS Research Mentoring Program.
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- Cocohoba JM, Althoff KN, Godfrey R, Palella FJ, Greenblatt RM. Influence of gender on receipt of guideline-based antiretroviral therapy in the era of HAART. AIDS Care. 2012; 24(1):20-9.
- Kuniholm MH, Gao X, Xue X, Kovacs A, Marti D, Thio CL, Peters MG, Greenblatt RM, Goedert JJ, Cohen MH, Minkoff H, Gange SJ, Anastos K, Fazzari M, Young MA, Strickler HD, Carrington M. The relation of HLA genotype to hepatitis C viral load and markers of liver fibrosis in HIV-infected and HIV-uninfected women. J Infect Dis. 2011 Jun 15; 203(12):1807-14.
- Althoff KN, Eichelberger M, Gange SJ, Sharp GB, Gao J, Glesby MJ, Young M, Greenblatt RM, French AL, Villacres MC, Minkoff H. Seroincidence of 2009 H1N1 infection in HIV-infected and HIV-uninfected women prior to vaccine availability. AIDS. 2011 Jun 01; 25(9):1229-32.
- Gandhi M, Ameli N, Bacchetti P, Anastos K, Gange SJ, Minkoff H, Young M, Milam J, Cohen MH, Sharp GB, Huang Y, Greenblatt RM. Atazanavir concentration in hair is the strongest predictor of outcomes on antiretroviral therapy. Clin Infect Dis. 2011 May; 52(10):1267-75.
- Delwart E, Bernardin F, Lee TH, Winkelman V, Liu C, Sheppard H, Liu A, Greenblatt R, Anastos K, DeHovitz J, Nowicki M, Cohen M, Golub ET, Barbour J, Buchbinder S, Busch MP. Absence of reproducibly detectable low-level HIV viremia in highly exposed seronegative men and women. AIDS. 2011 Mar 13; 25(5):619-23.
- Shacklett BL, Greenblatt RM. Immune responses to HIV in the female reproductive tract, immunologic parallels with the gastrointestinal tract, and research implications. Am J Reprod Immunol. 2011 Mar; 65(3):230-41.
- Hessol NA, Napolitano LA, Smith D, Lie Y, Levine A, Young M, Cohen M, Minkoff H, Anastos K, D'Souza G, Greenblatt RM, Goedert JJ. HIV tropism and decreased risk of breast cancer. PLoS One. 2010 Dec 16; 5(12):e14349.
- Aumakhan B, Hardick A, Quinn TC, Laeyendecker O, Gange SJ, Beyrer C, Cox C, Anastos K, Cohen M, Greenblatt RM, Merenstein DJ, Minkoff H, Nowicki M, Gaydos CA. Genital herpes evaluation by quantitative TaqMan PCR: correlating single detection and quantity of HSV-2 DNA in cervicovaginal lavage fluids with cross-sectional and longitudinal clinical data. Virol J. 2010 Nov 18; 7:328.
- Cocohoba J, Hsu T, Greenblatt RM. Community Pharmacy Use Patterns of Women with HIV and Women At Risk for HIV in the San Francisco Bay Area. J Pharm Technol. 2010 Sep-Oct; 26(5):271-275.
- Merenstein DJ, Hu H, Robison E, Levine AM, Greenblatt R, Schwartz R, Weber K, Young M, Sharp G, Liu C. Relationship between complementary/alternative treatment use and illicit drug use among a cohort of women with, or at risk for, HIV infection. J Altern Complement Med. 2010 Sep; 16(9):989-93.
- Wilson TE, Jean-Louis G, Schwartz R, Golub ET, Cohen MH, Maki P, Greenblatt R, Massad LS, Robison E, Goparaju L, Lindau S. HIV infection and women's sexual functioning. J Acquir Immune Defic Syndr. 2010 Aug; 54(4):360-7.
- Ronquillo RE, Desai SN, Norris PJ, Golub ET, Greenblatt RM, Gange SJ, Landay AL. Elevated caspase-3 expression and T-cell activation in elite suppressors. J Acquir Immune Defic Syndr. 2010 May 01; 54(1):110-1.
- Kuniholm MH, Kovacs A, Gao X, Xue X, Marti D, Thio CL, Peters MG, Terrault NA, Greenblatt RM, Goedert JJ, Cohen MH, Minkoff H, Gange SJ, Anastos K, Fazzari M, Harris TG, Young MA, Strickler HD, Carrington M. Specific human leukocyte antigen class I and II alleles associated with hepatitis C virus viremia. Hepatology. 2010 May; 51(5):1514-22.
- Aumakhan B, Gaydos CA, Quinn TC, Beyrer C, Benning L, Minkoff H, Merenstein DJ, Cohen M, Greenblatt R, Nowicki M, Anastos K, Gange SJ. Clinical reactivations of herpes simplex virus type 2 infection and human immunodeficiency virus disease progression markers. PLoS One. 2010 Apr 01; 5(4):e9973.
- Althoff KN, Anastos K, Nelson KE, Celentano DD, Sharp GB, Greenblatt RM, French AL, Diamond DJ, Holman S, Young M, Gange SJ. Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons. Prev Med. 2010 May-Jun; 50(5-6):223-9.
- Terzian AS, Holman S, Nathwani N, Robison E, Weber K, Young M, Greenblatt RM, Gange SJ. Factors associated with preclinical disability and frailty among HIV-infected and HIV-uninfected women in the era of cART. J Womens Health (Larchmt). 2009 Dec; 18(12):1965-74.
- Rahangdale L, Greenblatt RM, Perry J, Darragh TM, Kobayashi A, Smith-McCune KK. In vivo effects of nonoxynol-9 on endometrial immune cell populations. J Acquir Immune Defic Syndr. 2009 Sep 01; 52(1):137-9.
- Feldman DN, Feldman JG, Greenblatt R, Anastos K, Pearce L, Cohen M, Gange S, Leanza S, Burk R. CYP1A1 genotype modifies the impact of smoking on effectiveness of HAART among women. AIDS Educ Prev. 2009 Jun; 21(3 Suppl):81-93.
- Gandhi M, Benet LZ, Bacchetti P, Kalinowski A, Anastos K, Wolfe AR, Young M, Cohen M, Minkoff H, Gange SJ, Greenblatt RM. Nonnucleoside reverse transcriptase inhibitor pharmacokinetics in a large unselected cohort of HIV-infected women. J Acquir Immune Defic Syndr. 2009 Apr 15; 50(5):482-91.
- Kahn JS, Greenblatt RM. Mentoring early-career scientists for HIV research careers. Am J Public Health. 2009 Apr; 99 Suppl 1:S37-42.
- Gandhi M, Ameli N, Bacchetti P, Gange SJ, Anastos K, Levine A, Hyman CL, Cohen M, Young M, Huang Y, Greenblatt RM. Protease inhibitor levels in hair strongly predict virologic response to treatment. AIDS. 2009 Feb 20; 23(4):471-8.
- Hessol NA, Holly EA, Efird JT, Minkoff H, Schowalter K, Darragh TM, Burk RD, Strickler HD, Greenblatt RM, Palefsky JM. Anal intraepithelial neoplasia in a multisite study of HIV-infected and high-risk HIV-uninfected women. AIDS. 2009 Jan 02; 23(1):59-70.
- Huang Y, Gandhi M, Greenblatt RM, Gee W, Lin ET, Messenkoff N. Sensitive analysis of anti-HIV drugs, efavirenz, lopinavir and ritonavir, in human hair by liquid chromatography coupled with tandem mass spectrometry. Rapid Commun Mass Spectrom. 2008 Nov; 22(21):3401-9.
- Seifer DB, Golub ET, Lambert-Messerlian G, Benning L, Anastos K, Watts DH, Cohen MH, Karim R, Young MA, Minkoff H, Greenblatt RM. Variations in serum müllerian inhibiting substance between white, black, and Hispanic women. Fertil Steril. 2009 Nov; 92(5):1674-8.
- Cocohoba J, Wang QJ, Cox C, Gange SJ, Cohen M, Glesby M, DeHovitz JA, Greenblatt RM. Consistency of initial antiretroviral therapy with HIV treatment guidelines in a US cohort of HIV-infected women. J Acquir Immune Defic Syndr. 2008 Mar 01; 47(3):377-83.