Phyllis Tien, MD
Professor, School of Medicine
Email: ptien@medicine.ucsf.edu
Biography
Dr. Tien is Professor of Medicine at the University of California, San Francisco and Chief of the Infectious Diseases Division at the San Francisco Veterans Affairs Health Care System. Her research program examines the mechanisms by which chronic viral infections (specifically HIV and HCV) and their associated metabolic and immune perturbations impact long term organ injury in adults. She has served in several leadership positions including Co-Chair of the Executive Committee of the Multicenter AIDS Cohort Study (MACS)/Women's Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS) and the MWCCS Steering Committee. The MWCCS integrates two of the largest and longest running NIH-funded prospective cohorts of adult men and women with and at risk for HIV in the U.S. She also serves as Chair of the Inter-CFAR Collaboration on HIV Research in Women and previously served as Chair of the NIH AIDS Clinical Epidemiology Study Section. She was a member of the Department of Health and Human Services Antiretroviral Guidelines Panel, and is currently a member of the NIAID AIDS Research Study Section and the NIH COVID-19 Treatment Guidelines Panel.
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- Ghotb A, Noworolski SM, Madden E, Scherzer R, Qayyum A, Pannell J, Ferrell L, Peters M, Tien PC. Adipose tissue and metabolic factors associated with steatosis in HIV/HCV coinfection: histology versus magnetic resonance spectroscopy. . 2010 Oct; 55(2):228-31.
- Estrella MM, Parekh RS, Abraham A, Astor BC, Szczech LA, Anastos K, Dehovitz JA, Merenstein DJ, Pearce CL, Tien PC, Cohen MH, Gange SJ. The impact of kidney function at highly active antiretroviral therapy initiation on mortality in HIV-infected women. . 2010 Oct; 55(2):217-20.
- Julie Womack, Phyllis C Tien. Mechanisms of HIV-related dyslipidemia. HIV Therapy. 2009 May 1; 3(3):283-292.
- Delaney JA, Scherzer R, Biggs ML, Shliplak MG, Polak JF, Currier JS, Kronmal RA, Wanke C, Bacchetti P, O'leary D, Tien PC, Grunfeld C. Associations of antiretroviral drug use and HIV-specific risk factors with carotid intima-media thickness. AIDS. 2010 Sep 10; 24(14):2201-9.
- Wyatt CM, Hoover DR, Shi Q, Seaberg E, Wei C, Tien PC, Karim R, Lazar J, Young MA, Cohen MH, Klotman PE, Anastos K. Microalbuminuria is associated with all-cause and AIDS mortality in women with HIV infection. . 2010 Sep; 55(1):73-7.
- Choi A, Scherzer R, Bacchetti P, Tien PC, Saag MS, Gibert CL, Szczech LA, Grunfeld C, Shlipak MG. Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons. Am J Kidney Dis. 2010 Nov; 56(5):872-82.
- Grunfeld C, Saag M, Cofrancesco J, Lewis CE, Kronmal R, Heymsfield S, Tien PC, Bacchetti P, Shlipak M, Scherzer R, Study of Fat Redistribution and Metabolic Change in HIV Infection (FRAM) . Regional adipose tissue measured by MRI over 5 years in HIV-infected and control participants indicates persistence of HIV-associated lipoatrophy. AIDS. 2010 Jul 17; 24(11):1717-26.
- Howard AA, Hoover DR, Anastos K, Wu X, Shi Q, Strickler HD, Cole SR, Cohen MH, Kovacs A, Augenbraun M, Latham PS, Tien PC. The effects of opiate use and hepatitis C virus infection on risk of diabetes mellitus in the Women's Interagency HIV Study. . 2010 Jun; 54(2):152-9.
- Kovacs A, Karim R, Mack WJ, Xu J, Chen Z, Operskalski E, Frederick T, Landay A, Voris J, Spencer LS, Young MA, Tien PC, Augenbraun M, Strickler HD, Al-Harthi L. Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus. J Infect Dis. 2010 Mar 15; 201(6):823-34.
- Westreich D, Cole SR, Tien PC, Chmiel JS, Kingsley L, Funk MJ, Anastos K, Jacobson LP. Time scale and adjusted survival curves for marginal structural cox models. Am J Epidemiol. 2010 Mar 15; 171(6):691-700.
- Yin MT, Lu D, Cremers S, Tien PC, Cohen MH, Shi Q, Shane E, Golub ET, Anastos K. Short-term bone loss in HIV-infected premenopausal women. . 2010 Feb; 53(2):202-8.
- Cockerham L, Scherzer R, Zolopa A, Rimland D, Lewis CE, Bacchetti P, Grunfeld C, Shlipak M, Tien PC. Association of HIV infection, demographic and cardiovascular risk factors with all-cause mortality in the recent HAART era. . 2010 Jan; 53(1):102-6.
- Glesby MJ, Hoover DR, Shi Q, Danoff A, Howard A, Tien P, Merenstein D, Cohen M, Golub E, Dehovitz J, Nowicki M, Anastos K. Glycated haemoglobin in diabetic women with and without HIV infection: data from the Women's Interagency HIV Study. Antivir Ther. 2010; 15(4):571-7.
- Womack JA, Scherzer R, Cole SR, Fennie K, Williams AB, Grey M, Minkoff H, Anastos K, Cohen MH, Tien PC. Hormonal contraception and metabolic outcomes in women with or at risk for HIV infection. . 2009 Dec; 52(5):581-7.
- Boodram B, Plankey MW, Cox C, Tien PC, Cohen MH, Anastos K, Karim R, Hyman C, Hershow RC. Prevalence and correlates of elevated body mass index among HIV-positive and HIV-negative women in the Women's Interagency HIV Study. AIDS Patient Care STDS. 2009 Dec; 23(12):1009-16.
- Cole SR, Jacobson LP, Tien PC, Kingsley L, Chmiel JS, Anastos K. Using marginal structural measurement-error models to estimate the long-term effect of antiretroviral therapy on incident AIDS or death. Am J Epidemiol. 2010 Jan 01; 171(1):113-22.
- Grunfeld C, Delaney JA, Wanke C, Currier JS, Scherzer R, Biggs ML, Tien PC, Shlipak MG, Sidney S, Polak JF, O'Leary D, Bacchetti P, Kronmal RA. Preclinical atherosclerosis due to HIV infection: carotid intima-medial thickness measurements from the FRAM study. AIDS. 2009 Sep 10; 23(14):1841-9.
- Bacchetti P, Tien PC, Seaberg EC, O'Brien TR, Augenbraun MH, Kral AH, Busch MP, Edlin BR. Estimating past hepatitis C infection risk from reported risk factor histories: implications for imputing age of infection and modeling fibrosis progression. BMC Infect Dis. 2007 Dec 10; 7:145.
- Julie Womack, Phyllis C Tien. Mechanisms of HIV-related dyslipidemia. HIV Therapy. 2009 May 1; 3(3):283-292.
- Tsui JI, Whooley MA, Monto A, Seal K, Tien PC, Shlipak M. Association of hepatitis C virus seropositivity with inflammatory markers and heart failure in persons with coronary heart disease: data from the Heart and Soul study. J Card Fail. 2009 Jun; 15(5):451-6.
- Tien PC, Schneider MF, Cole SR, Levine AM, Cohen M, DeHovitz J, Young M, Justman JE. Antiretroviral therapy exposure and insulin resistance in the Women's Interagency HIV study. . 2008 Dec 01; 49(4):369-76.
- Noworolski SM, Tien PC, Merriman R, Vigneron DB, Qayyum A. Respiratory motion-corrected proton magnetic resonance spectroscopy of the liver. Magn Reson Imaging. 2009 May; 27(4):570-6.
- Tsui JI, French AL, Seaberg EC, Augenbraun M, Nowicki M, Peters M, Tien PC. Prevalence and long-term effects of occult hepatitis B virus infection in HIV-infected women. Clin Infect Dis. 2007 Sep 15; 45(6):736-40.
- Kaplan RC, Kingsley LA, Gange SJ, Benning L, Jacobson LP, Lazar J, Anastos K, Tien PC, Sharrett AR, Hodis HN. Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and men. AIDS. 2008 Aug 20; 22(13):1615-24.
- Plankey M, Bacchetti P, Jin C, Grimes B, Hyman C, Cohen M, Howard AA, Tien PC. Self-perception of body fat changes and HAART adherence in the Women's Interagency HIV Study. AIDS Behav. 2009 Feb; 13(1):53-9.