Phyllis Tien, MD

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Phyllis Tien, MD

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Professor, School of Medicine
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Dr. Tien is Professor of Medicine at the University of California, San Francisco and Chief of the Infectious Diseases Division at the San Francisco Veterans Affairs Health Care System. Her research program examines the mechanisms by which chronic viral infections (specifically HIV and HCV) and their associated metabolic and immune perturbations impact long term organ injury in adults. She has served in several leadership positions including Co-Chair of the Executive Committee of the Multicenter AIDS Cohort Study (MACS)/Women's Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS) and the MWCCS Steering Committee. The MWCCS integrates two of the largest and longest running NIH-funded prospective cohorts of adult men and women with and at risk for HIV in the U.S. She also serves as Chair of the Inter-CFAR Collaboration on HIV Research in Women and previously served as Chair of the NIH AIDS Clinical Epidemiology Study Section. She was a member of the Department of Health and Human Services Antiretroviral Guidelines Panel, and is currently a member of the NIAID AIDS Research Study Section and the NIH COVID-19 Treatment Guidelines Panel.
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  1. Price JC, Dodge JL, Ma Y, Scherzer R, Korn N, Tillinghast K, Peters MG, Noworolski S, Tien PC. Controlled attenuation parameter and magnetic resonance spectroscopy-measured liver steatosis are discordant in obese HIV-infected adults. AIDS. 2017 09 24; 31(15):2119-2125.
    http://www.ncbi.nlm.nih.gov/pubmed/27677166
  2. Malhotra R, Nguyen HA, Benavente O, Mete M, Howard BV, Mant J, Odden MC, Peralta CA, Cheung AK, Nadkarni GN, Coleman RL, Holman RR, Zanchetti A, Peters R, Beckett N, Staessen JA, Ix JH. Association Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5: A Systematic Review and Meta-analysis. JAMA Intern Med. 2017 10 01; 177(10):1498-1505.
    http://www.ncbi.nlm.nih.gov/pubmed/27993956
  3. Reid MJA, Baxi SM, Sheira LA, Landay AL, Frongillo EA, Adedimeji A, Cohen MH, Wentz E, Gustafson DR, Merenstein D, Hunt PW, Tien PC, Weiser SD, Women's Interagency HIV Study (WIHS) . Higher Body Mass Index Is Associated With Greater Proportions of Effector CD8+ T Cells Expressing CD57 in Women Living With HIV. J Acquir Immune Defic Syndr. 2017 08 15; 75(5):e132-e141.
    http://www.ncbi.nlm.nih.gov/pubmed/27792683
  4. Price JC, Tien PC. Reply. Hepatology. 2017 08; 66(2):674-675.
    http://www.ncbi.nlm.nih.gov/pubmed/27861378
  5. Imp BM, Rubin LH, Tien PC, Plankey MW, Golub ET, French AL, Valcour VG. Monocyte Activation Is Associated With Worse Cognitive Performance in HIV-Infected Women With Virologic Suppression. J Infect Dis. 2017 Jan 01; 215(1):114-121.
    http://www.ncbi.nlm.nih.gov/pubmed/27789726
  6. Price JC, Ma Y, Scherzer R, Korn N, Tillinghast K, Peters MG, Noworolski SM, Tien PC. Human immunodeficiency virus-infected and uninfected adults with non-genotype 3 hepatitis C virus have less hepatic steatosis than adults with neither infection. Hepatology. 2017 03; 65(3):853-863.
    http://www.ncbi.nlm.nih.gov/pubmed/27490638
  7. Jennifer Price, Jennifer Dodge, Yifei Ma, Rebecca Scherzer, Natalie Korn, Kyle Tillinghast, Marion Peters, Sue Noworolski, Phyllis Tien. Correlation of Controlled Attenuation Parameter and Magnetic Resonance Spectroscopy Measurements of Hepatic Steatosis in HIV-positive Adults. The American Journal of Gastroenterology. 2016 Oct 1; 111:s371.
  8. Reid M, Ma Y, Scherzer R, Price JC, French AL, Plankey MW, Grunfeld C, Tien PC. Higher CD163 levels are associated with insulin resistance in hepatitis C virus-infected and HIV-infected adults. AIDS. 2017 01 28; 31(3):385-393.
    http://www.ncbi.nlm.nih.gov/pubmed/27557039
  9. Valcour VG, Rubin LH, Obasi MU, Maki PM, Peters MG, Levin S, Crystal HA, Young MA, Mack WJ, Cohen MH, Pierce CB, Adimora AA, Tien PC, Women's Interagency HIV Study Protocol Team . Liver Fibrosis Linked to Cognitive Performance in HIV and Hepatitis C. . 2016 07 01; 72(3):266-73.
    http://www.ncbi.nlm.nih.gov/pubmed/26885801
  10. Turan B, Smith W, Cohen MH, Wilson TE, Adimora AA, Merenstein D, Adedimeji A, Wentz EL, Foster AG, Metsch L, Tien PC, Weiser SD, Turan JM. Mechanisms for the Negative Effects of Internalized HIV-Related Stigma on Antiretroviral Therapy Adherence in Women: The Mediating Roles of Social Isolation and Depression. J Acquir Immune Defic Syndr. 2016 06 01; 72(2):198-205.
    http://www.ncbi.nlm.nih.gov/pubmed/26885803
  11. Kelly EM, Dodge JL, Sarkar M, French AL, Tien PC, Glesby MJ, Golub ET, Augenbraun M, Plankey M, Peters MG. Marijuana Use Is Not Associated With Progression to Advanced Liver Fibrosis in HIV/Hepatitis C Virus-coinfected Women. Clin Infect Dis. 2016 08 15; 63(4):512-8.
    http://www.ncbi.nlm.nih.gov/pubmed/27225241
  12. Lyndsey Hornbuckle, C. Christina Mehta, Phyllis Tien, David Hanna, Jason Lazar, Lorie Benning, Mardge Cohen, Wendy Mack, Michael Plankey, Gina Wingood. Relationship Between Physical Activity And Cardiovascular Disease Risk In The Women’s Interagency HIV Study. Medicine & Science in Sports & Exercise. 2016 May 1; 48(5S):227.
  13. Peters MG, Bacchetti P, Boylan R, French AL, Tien PC, Plankey MW, Glesby MJ, Augenbraun M, Golub ET, Karim R, Parkes J, Rosenberg W. Enhanced liver fibrosis marker as a noninvasive predictor of mortality in HIV/hepatitis C virus-coinfected women from a multicenter study of women with or at risk for HIV. AIDS. 2016 Mar 13; 30(5):723-9.
    http://www.ncbi.nlm.nih.gov/pubmed/26595542
  14. Sharma A, Ma Y, Scherzer R, Wheeler AL, Cohen M, Gustafson DR, Keating SM, Yin MT, Tien PC. Brief Report: Association of Adipokines With Bone Mineral Density in HIV-Infected and HIV-Uninfected Women. . 2016 Dec 01; 73(4):433-437.
    http://www.ncbi.nlm.nih.gov/pubmed/27066296
  15. Erlandson KM, Zhang L, Lake JE, Schrack J, Althoff K, Sharma A, Tien PC, Margolick JB, Jacobson LP, Brown TT. Changes in weight and weight distribution across the lifespan among HIV-infected and -uninfected men and women. Medicine (Baltimore). 2016 Nov; 95(46):e5399.
    http://www.ncbi.nlm.nih.gov/pubmed/26761519
  16. Imp BM, Rubin LH, Tien PC, Plankey MW, Golub ET, French AL, Valcour VG. Monocyte Activation Is Associated With Worse Cognitive Performance in HIV-Infected Women With Virologic Suppression. J Infect Dis. 2017 Jan 01; 215(1):114-121.
    http://www.ncbi.nlm.nih.gov/pubmed/26754833
  17. E.M. Kelly, J. Dodge, P. Bacchetti, M. Sarkar, A. French, P. Tien, M. Glesby, E. Golub, M. Augenbraun, M. Plankey, M. Peters. PS073 Light to Moderate Alcohol Use is not Associated with Long-Term Progression of Liver Fibrosis in Hiv Hcv Coinfected Women. Journal of Hepatology. 2016 Jan 1; 64(2):s171-s172.
  18. Gowda C, Brown TT, Compher C, Forde KA, Kostman J, Shaw PA, Tien PC, Lo Re V. Prevalence and predictors of low muscle mass in HIV/viral hepatitis coinfection. AIDS. 2016 10 23; 30(16):2519-2528.
    http://www.ncbi.nlm.nih.gov/pubmed/26699870
  19. Jennifer Price, Jennifer Dodge, Yifei Ma, Rebecca Scherzer, Natalie Korn, Kyle Tillinghast, Marion Peters, Sue Noworolski, Phyllis Tien. Correlation of Controlled Attenuation Parameter and Magnetic Resonance Spectroscopy Measurements of Hepatic Steatosis in HIV-positive Adults. The American Journal of Gastroenterology. 2016 Oct 1; 111:s371.
    http://www.ncbi.nlm.nih.gov/pubmed/26493063
  20. Swanson S, Ma Y, Scherzer R, Huhn G, French AL, Plankey MW, Grunfeld C, Rosenberg WM, Peters MG, Tien PC. Association of HIV, Hepatitis C Virus, and Liver Fibrosis Severity With the Enhanced Liver Fibrosis Score. J Infect Dis. 2016 Apr 01; 213(7):1079-86.
    http://www.ncbi.nlm.nih.gov/pubmed/26621911
  21. Valcour VG, Rubin LH, Obasi MU, Maki PM, Peters MG, Levin S, Crystal HA, Young MA, Mack WJ, Cohen MH, Pierce CB, Adimora AA, Tien PC, Women's Interagency HIV Study Protocol Team . Liver Fibrosis Linked to Cognitive Performance in HIV and Hepatitis C. . 2016 07 01; 72(3):266-73.
    http://www.ncbi.nlm.nih.gov/pubmed/26322667
  22. Shah S, Ma Y, Scherzer R, Huhn G, French AL, Plankey M, Peters MG, Grunfeld C, Tien PC. Association of HIV, hepatitis C virus and liver fibrosis severity with interleukin-6 and C-reactive protein levels. AIDS. 2015 Jul 17; 29(11):1325-33.
    http://www.ncbi.nlm.nih.gov/pubmed/25870985
  23. Kelly EM, Dodge JL, Sarkar M, French AL, Tien PC, Glesby MJ, Golub ET, Augenbraun M, Plankey M, Peters MG. Marijuana Use Is Not Associated With Progression to Advanced Liver Fibrosis in HIV/Hepatitis C Virus-coinfected Women. Clin Infect Dis. 2016 08 15; 63(4):512-8.
    http://www.ncbi.nlm.nih.gov/pubmed/26061798
  24. Lyndsey Hornbuckle, C. Christina Mehta, Phyllis Tien, David Hanna, Jason Lazar, Lorie Benning, Mardge Cohen, Wendy Mack, Michael Plankey, Gina Wingood. Relationship Between Physical Activity And Cardiovascular Disease Risk In The Women’s Interagency HIV Study. Medicine & Science in Sports & Exercise. 2016 May 1; 48(5S):227.
    http://www.ncbi.nlm.nih.gov/pubmed/25921719
  25. Peters MG, Bacchetti P, Boylan R, French AL, Tien PC, Plankey MW, Glesby MJ, Augenbraun M, Golub ET, Karim R, Parkes J, Rosenberg W. Enhanced liver fibrosis marker as a noninvasive predictor of mortality in HIV/hepatitis C virus-coinfected women from a multicenter study of women with or at risk for HIV. AIDS. 2016 Mar 13; 30(5):723-9.
    http://www.ncbi.nlm.nih.gov/pubmed/25904369