Phyllis Tien, MD

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Phyllis Tien, MD

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Professor, School of Medicine
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Dr. Tien is Professor of Medicine at the University of California, San Francisco and Chief of the Infectious Diseases Division at the San Francisco Veterans Affairs Health Care System. Her research program examines the mechanisms by which chronic viral infections (specifically HIV and HCV) and their associated metabolic and immune perturbations impact long term organ injury in adults. She has served in several leadership positions including Co-Chair of the Executive Committee of the Multicenter AIDS Cohort Study (MACS)/Women's Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS) and the MWCCS Steering Committee. The MWCCS integrates two of the largest and longest running NIH-funded prospective cohorts of adult men and women with and at risk for HIV in the U.S. She also serves as Chair of the Inter-CFAR Collaboration on HIV Research in Women and previously served as Chair of the NIH AIDS Clinical Epidemiology Study Section. She was a member of the Department of Health and Human Services Antiretroviral Guidelines Panel, and is currently a member of the NIAID AIDS Research Study Section and the NIH COVID-19 Treatment Guidelines Panel.
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  1. Galaviz KI, Schneider MF, Tien PC, Mehta CC, Ofotokun I, Colasanti J, Marconi VC, Palar K, Wingood G, Adimora AA, Alcaide M, Cohen MH, Gustafson D, Karim R, Konkle-Parker D, Merenstein D, Sharma A, Ali MK. Predicting diabetes risk among HIV-positive and HIV-negative women. AIDS. 2018 11 28; 32(18):2767-2775.
    http://www.ncbi.nlm.nih.gov/pubmed/29942823
  2. Hanna DB, Moon JY, Haberlen SA, French AL, Palella FJ, Gange SJ, Witt MD, Kassaye S, Lazar JM, Tien PC, Feinstein MJ, Kingsley LA, Post WS, Kaplan RC, Hodis HN, Anastos K. Carotid artery atherosclerosis is associated with mortality in HIV-positive women and men. AIDS. 2018 10 23; 32(16):2393-2403.
    http://www.ncbi.nlm.nih.gov/pubmed/29438198
  3. Kushner T, Cohen J, Tien PC, Terrault NA. Evaluating Women's Preferences for Hepatitis C Treatment During Pregnancy. Hepatol Commun. 2018 Nov; 2(11):1306-1310.
    http://www.ncbi.nlm.nih.gov/pubmed/29881632
  4. Erik Ehinger, Pramod Akula Bala, Juan Lin, David B Hanna, Karin Mueller, Livia Baas, Qibin Qi, Tao Wang, Konrad Buscher, Yongmei Liu, Kathryn Anastos, Jason M Lazar, Wendy J Mack, Phyllis C Tien, Mardge H Cohen, Igho Ofotokun, Stephen Gange, Sonya L Heath, Howard N Hodis, Russell P Tracy, Alan L Landay, Robert C Kaplan, Klaus Ley. Abstract 410: Statin Use May Alleviate Coagulation- and Inflammation-associated Gene Expression in Circulating Classical Monocytes in Women With Chronic HIV-1 Infection. Arteriosclerosis Thrombosis and Vascular Biology. 2018 May 1; 38(Suppl_1).
  5. Adimora AA, Ramirez C, Benning L, Greenblatt RM, Kempf MC, Tien PC, Kassaye SG, Anastos K, Cohen M, Minkoff H, Wingood G, Ofotokun I, Fischl MA, Gange S. Cohort Profile: The Women's Interagency HIV Study (WIHS). Int J Epidemiol. 2018 04 01; 47(2):393-394i.
    http://www.ncbi.nlm.nih.gov/pubmed/29688497
  6. Reid M, Ma Y, Scherzer R, Price JC, French AL, Huhn GD, Plankey MW, Peters M, Grunfeld C, Tien PC. Contribution of Liver Fibrosis and Microbial Translocation to Immune Activation in Persons Infected With HIV and/or Hepatitis C Virus. J Infect Dis. 2018 03 28; 217(8):1289-1297.
    http://www.ncbi.nlm.nih.gov/pubmed/29304196
  7. Willis SJ, Cole SR, Westreich D, Edmonds A, Hurt CB, Albrecht S, Anastos K, Augenbraun M, Fischl M, French AL, Kalapila AG, Karim R, Peters MG, Plankey M, Seaberg EC, Tien PC, Adimora AA. Chronic hepatitis C virus infection and subsequent HIV viral load among women with HIV initiating antiretroviral therapy. AIDS. 2018 03 13; 32(5):653-661.
    http://www.ncbi.nlm.nih.gov/pubmed/29334550
  8. Glesby MJ, Hanna DB, Hoover DR, Shi Q, Yin MT, Tien PC, Cohen M, Anastos K, Sharma A. Abdominal fat depots, insulin resistance, and incident diabetes mellitus in women with and without HIV infection. AIDS. 2018 07 31; 32(12):1643-1650.
    http://www.ncbi.nlm.nih.gov/pubmed/29210836
  9. Yang J, Sharma A, Shi Q, Anastos K, Cohen MH, Golub ET, Gustafson D, Merenstein D, Mack WJ, Tien PC, Nieves JW, Yin MT. Improved fracture prediction using different fracture risk assessment tool adjustments in HIV-infected women. AIDS. 2018 07 31; 32(12):1699-1706.
    http://www.ncbi.nlm.nih.gov/pubmed/30112518
  10. Kazakia GJ, Carballido-Gamio J, Lai A, Nardo L, Facchetti L, Pasco C, Zhang CA, Han M, Parrott AH, Tien P, Krug R. Trabecular bone microstructure is impaired in the proximal femur of human immunodeficiency virus-infected men with normal bone mineral density. Quant Imaging Med Surg. 2018 Feb; 8(1):5-13.
    http://www.ncbi.nlm.nih.gov/pubmed/29541618
  11. Moran CA, Sheth AN, Mehta CC, Hanna DB, Gustafson DR, Plankey MW, Mack WJ, Tien PC, French AL, Golub ET, Quyyumi A, Kaplan RC, Ofotokun I. The association of C-reactive protein with subclinical cardiovascular disease in HIV-infected and HIV-uninfected women. AIDS. 2018 05 15; 32(8):999-1006.
    http://www.ncbi.nlm.nih.gov/pubmed/28933703
  12. Turan B, Rogers AJ, Rice WS, Atkins GC, Cohen MH, Wilson TE, Adimora AA, Merenstein D, Adedimeji A, Wentz EL, Ofotokun I, Metsch L, Tien PC, Johnson MO, Turan JM, Weiser SD. Association between Perceived Discrimination in Healthcare Settings and HIV Medication Adherence: Mediating Psychosocial Mechanisms. AIDS Behav. 2017 Dec; 21(12):3431-3439.
    http://www.ncbi.nlm.nih.gov/pubmed/29081045
  13. Spinelli MA, Frongillo EA, Sheira LA, Palar K, Tien PC, Wilson T, Merenstein D, Cohen M, Adedimeji A, Wentz E, Adimora AA, Metsch LR, Turan JM, Kushel MB, Weiser SD. Food Insecurity is Associated with Poor HIV Outcomes Among Women in the United States. AIDS Behav. 2017 Dec; 21(12):3473-3477.
    http://www.ncbi.nlm.nih.gov/pubmed/29119474
  14. Adimora AA, Ramirez C, Benning L, Greenblatt RM, Kempf MC, Tien PC, Kassaye SG, Anastos K, Cohen M, Minkoff H, Wingood G, Ofotokun I, Fischl MA, Gange S. Cohort Profile: The Women's Interagency HIV Study (WIHS). Int J Epidemiol. 2018 04 01; 47(2):393-394i.
    http://www.ncbi.nlm.nih.gov/pubmed/29079161
  15. Kelly EM, Dodge JL, Bacchetti P, Sarkar M, French AL, Tien PC, Glesby MJ, Golub ET, Augenbraun M, Plankey M, Peters MG. Moderate Alcohol Use Is Not Associated With Fibrosis Progression in Human Immunodeficiency Virus/Hepatitis C Virus-Coinfected Women: A Prospective Cohort Study. Clin Infect Dis. 2017 Nov 29; 65(12):2050-2056.
    http://www.ncbi.nlm.nih.gov/pubmed/29020382
  16. Willis SJ, Cole SR, Westreich D, Edmonds A, Hurt CB, Albrecht S, Anastos K, Augenbraun M, Fischl M, French AL, Kalapila AG, Karim R, Peters MG, Plankey M, Seaberg EC, Tien PC, Adimora AA. Chronic hepatitis C virus infection and subsequent HIV viral load among women with HIV initiating antiretroviral therapy. AIDS. 2018 03 13; 32(5):653-661.
    http://www.ncbi.nlm.nih.gov/pubmed/28978973
  17. Price JC, Dodge JL, Ma Y, Scherzer R, Korn N, Tillinghast K, Peters MG, Noworolski S, Tien PC. Controlled attenuation parameter and magnetic resonance spectroscopy-measured liver steatosis are discordant in obese HIV-infected adults. AIDS. 2017 09 24; 31(15):2119-2125.
    http://www.ncbi.nlm.nih.gov/pubmed/28723710
  18. Sarkar M, Terrault N, Duwaerts CC, Tien P, Cedars MI, Huddleston H. The Association of Hispanic Ethnicity with Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome. Curr Opin Gynecol Obstet. 2018 02 20; 1(1):24-33.
    http://www.ncbi.nlm.nih.gov/pubmed/28444147
  19. Reid MJA, Baxi SM, Sheira LA, Landay AL, Frongillo EA, Adedimeji A, Cohen MH, Wentz E, Gustafson DR, Merenstein D, Hunt PW, Tien PC, Weiser SD. Higher Body Mass Index Is Associated With Greater Proportions of Effector CD8+ T Cells Expressing CD57 in Women Living With HIV. J Acquir Immune Defic Syndr. 2017 08 15; 75(5):e132-e141.
    http://www.ncbi.nlm.nih.gov/pubmed/28328551
  20. Sharma A, Hoover DR, Shi Q, Holman S, Plankey MW, Tien PC, Weber KM, Floris-Moore M, Bolivar HH, Vance DE, Golub ET, Holstad MM, Yin MT. Longitudinal study of falls among HIV-infected and uninfected women: the role of cognition. Antivir Ther. 2018; 23(2):179-190.
    http://www.ncbi.nlm.nih.gov/pubmed/28422311
  21. Turan B, Rogers AJ, Rice WS, Atkins GC, Cohen MH, Wilson TE, Adimora AA, Merenstein D, Adedimeji A, Wentz EL, Ofotokun I, Metsch L, Tien PC, Johnson MO, Turan JM, Weiser SD. Association between Perceived Discrimination in Healthcare Settings and HIV Medication Adherence: Mediating Psychosocial Mechanisms. AIDS Behav. 2017 Dec; 21(12):3431-3439.
    http://www.ncbi.nlm.nih.gov/pubmed/28199691
  22. Price JC, Ma Y, Scherzer R, Korn N, Tillinghast K, Peters MG, Noworolski SM, Tien PC. Human immunodeficiency virus-infected and uninfected adults with non-genotype 3 hepatitis C virus have less hepatic steatosis than adults with neither infection. Hepatology. 2017 03; 65(3):853-863.
    http://www.ncbi.nlm.nih.gov/pubmed/27981599
  23. Reid M, Price JC, Tien PC. Hepatitis C Virus Infection in the Older Patient. Infect Dis Clin North Am. 2017 12; 31(4):827-838.
    http://www.ncbi.nlm.nih.gov/pubmed/28081037
  24. Kardashian A, Ma Y, Scherzer R, Price JC, Sarkar M, Korn N, Tillinghast K, Peters MG, Noworolski SM, Tien PC. Sex differences in the association of HIV infection with hepatic steatosis. AIDS. 2017 01 28; 31(3):365-373.
    http://www.ncbi.nlm.nih.gov/pubmed/27831949
  25. Price JC, Tien PC. Editorial: Statins and Liver Disease: Is it Time to Recommend Statins to Prevent Liver Disease Progression? Am J Gastroenterol. 2017 Oct; 112(10):1506-1507.
    http://www.ncbi.nlm.nih.gov/pubmed/27835618