Phyllis Tien, MD

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Phyllis Tien, MD

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Professor, School of Medicine
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Dr. Tien is Professor of Medicine at the University of California, San Francisco and Chief of the Infectious Diseases Division at the San Francisco Veterans Affairs Health Care System. Her research program examines the mechanisms by which chronic viral infections (specifically HIV and HCV) and their associated metabolic and immune perturbations impact long term organ injury in adults. She has served in several leadership positions including Co-Chair of the Executive Committee of the Multicenter AIDS Cohort Study (MACS)/Women's Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS) and the MWCCS Steering Committee. The MWCCS integrates two of the largest and longest running NIH-funded prospective cohorts of adult men and women with and at risk for HIV in the U.S. She also serves as Chair of the Inter-CFAR Collaboration on HIV Research in Women and previously served as Chair of the NIH AIDS Clinical Epidemiology Study Section. She was a member of the Department of Health and Human Services Antiretroviral Guidelines Panel, and is currently a member of the NIAID AIDS Research Study Section and the NIH COVID-19 Treatment Guidelines Panel.
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  1. Ross RD, Sharma A, Shi Q, Hoover DR, Weber KM, Tien PC, French AL, Al-Harthi L, Yin MT. Circulating sclerostin is associated with bone mineral density independent of HIV-serostatus. Bone Rep. 2020 Jun; 12:100279.
    http://www.ncbi.nlm.nih.gov/pubmed/32248873
  2. Crockett KB, Entler KJ, Brodie E, Kempf MC, Konkle-Parker D, Wilson TE, Tien PC, Wingood G, Neilands TB, Johnson MO, Weiser SD, Turan JM, Turan B. Brief Report: Linking Depressive Symptoms to Viral Nonsuppression Among Women With HIV Through Adherence Self-Efficacy and ART Adherence. J Acquir Immune Defic Syndr. 2020 04 01; 83(4):340-344.
    http://www.ncbi.nlm.nih.gov/pubmed/32097193
  3. Whittle HJ, Wolfe WR, Sheira LA, Frongillo EA, Palar K, Merenstein D, Wilson TE, Adedimeji A, Cohen MH, Wentz EL, Tien PC, Weiser SD. Associations between food insecurity and psychotropic medication use among women living with HIV in the United States. Epidemiol Psychiatr Sci. 2020 Apr 06; 29:e113.
    http://www.ncbi.nlm.nih.gov/pubmed/31828462
  4. Kovacs AAZ, Kono N, Wang CH, Wang D, Frederick T, Operskalski E, Tien PC, French AL, Minkoff H, Kassaye S, T Golub E, Aouizerat BE, Kuniholm MH, Millstein J. Association of HLA Genotype With T-Cell Activation in Human Immunodeficiency Virus (HIV) and HIV/Hepatitis C Virus-Coinfected Women. J Infect Dis. 2020 03 16; 221(7):1156-1166.
    http://www.ncbi.nlm.nih.gov/pubmed/31802115
  5. Claudio A Bravo, Jee-Young Moon, Jean Claude Uwamungu, Robert Kaplan, Kathryn Anastos, Carlos J Rodriguez, Wendy S Post, Stephen J Gange, Seble Kassaye, Jason M Lazar, Wendy Mack, Nataliya Pyslar, Phyllis Tien, Howard N Hodis, David B Hanna. Abstract P322: Association of Hiv Infection With Carotid Artery Plaque Echomorphology in the Women’s Interagency HIV Study (wihs). Circulation. 2020 Mar 3; 141(Suppl_1).
  6. Juan Lin, David B Hanna, Qibin Qi, tao wang, Karin A Mueller, Yanal Ghosheh, Kathryn Anastos, Jason M LAZAR, Wendy MacK, Phyllis Tien, MARDGE COHEN, ofotokun igho, Stephen Gange, SONIA HEATH, Russell P Tracy, Howard N Hodis, ALAN LANDAY, Robert Kaplan, Klaus F Ley. Abstract P323: HIV- and Subclinical Cardiovascular Disease-specific Transcriptomes in Nonclassical Monocytes: The Women’s Interagency HIV Study. Circulation. 2020 Mar 3; 141(Suppl_1).
  7. Tien PC, Duarte M, Roque A, Price J. MRE and ELF in Liver Fibrosis Assessment: Are Two Better Than One? Dig Dis Sci. 2020 04; 65(4):928-930.
    http://www.ncbi.nlm.nih.gov/pubmed/31913989
  8. Kardashian A, Peters MG, Tien PC, Price JC. The Pathogenesis of Liver Disease in People Living With Human Immunodeficiency Virus: The Emerging Role of the Microbiome. Clin Liver Dis (Hoboken). 2020 Jan; 15(1):46-51.
    http://www.ncbi.nlm.nih.gov/pubmed/32104578
  9. Crockett KB, Entler KJ, Brodie E, Kempf MC, Konkle-Parker D, Wilson TE, Tien PC, Wingood G, Neilands TB, Johnson MO, Weiser SD, Turan JM, Turan B. Linking Depressive Symptoms to Viral Non-suppression among Women with HIV through Adherence Self-Efficacy and ART Adherence. J Acquir Immune Defic Syndr. 2020 Jan 03.
    http://www.ncbi.nlm.nih.gov/pubmed/31904702
  10. Juan Lin, David B Hanna, Qibin Qi, tao wang, Karin A Mueller, Yanal Ghosheh, Kathryn Anastos, Jason M LAZAR, Wendy MacK, Phyllis Tien, MARDGE COHEN, ofotokun igho, Stephen Gange, SONIA HEATH, Russell P Tracy, Howard N Hodis, ALAN LANDAY, Robert Kaplan, Klaus F Ley. Abstract P323: HIV- and Subclinical Cardiovascular Disease-specific Transcriptomes in Nonclassical Monocytes: The Women’s Interagency HIV Study. Circulation. 2020 Mar 3; 141(Suppl_1).
    http://www.ncbi.nlm.nih.gov/pubmed/31504710
  11. Foreman SC, Wu PH, Kuang R, John MD, Tien PC, Link TM, Krug R, Kazakia GJ. Factors associated with bone microstructural alterations assessed by HR-pQCT in long-term HIV-infected individuals. Bone. 2020 04; 133:115210.
    http://www.ncbi.nlm.nih.gov/pubmed/31874226
  12. Kardashian A, Peters MG, Tien PC, Price JC. The Pathogenesis of Liver Disease in People Living With Human Immunodeficiency Virus: The Emerging Role of the Microbiome. Clin Liver Dis (Hoboken). 2020 Jan; 15(1):46-51.
    http://www.ncbi.nlm.nih.gov/pubmed/31709815
  13. S. Moron-Lopez, G. Xie, P. Kim, J. Wong, J. Price, N. Elnachef, R. Greenblatt, P. Tien, N. Roan, S. Yukl. OP 7.6 Tissue-specific differences in the mechanisms that govern HIV latency in blood, liver, gut and genital tract in ART-suppressed women. Journal of virus eradication. 2019 Dec 1; 5:40.
  14. Crockett KB, Entler KJ, Brodie E, Kempf MC, Konkle-Parker D, Wilson TE, Tien PC, Wingood G, Neilands TB, Johnson MO, Weiser SD, Turan JM, Turan B. Linking Depressive Symptoms to Viral Non-suppression among Women with HIV through Adherence Self-Efficacy and ART Adherence. J Acquir Immune Defic Syndr. 2020 Jan 03.
    http://www.ncbi.nlm.nih.gov/pubmed/31760320
  15. Golovaty I, Tien PC, Price JC, Sheira L, Seligman H, Weiser SD. Food Insecurity May Be an Independent Risk Factor Associated with Nonalcoholic Fatty Liver Disease among Low-Income Adults in the United States. J Nutr. 2020 01 01; 150(1):91-98.
    http://www.ncbi.nlm.nih.gov/pubmed/31729142
  16. Foreman SC, Wu PH, Kuang R, John MD, Tien PC, Link TM, Krug R, Kazakia GJ. Factors associated with bone microstructural alterations assessed by HR-pQCT in long-term HIV-infected individuals. Bone. 2020 04; 133:115210.
    http://www.ncbi.nlm.nih.gov/pubmed/31335806
  17. Johnston CD, Hoover DR, Shi Q, Sharma A, Hanna DB, Anastos K, Tien PC, Fischl M, Gustafson D, Spence A, Karim R, French A, Schneider M, Adimora AA, Moran C, Konkle-Parker D, Glesby MJ. White Blood Cell Counts, Lymphocyte Subsets, and Incident Diabetes Mellitus in Women Living With and Without HIV. AIDS Res Hum Retroviruses. 2020 02; 36(2):131-133.
    http://www.ncbi.nlm.nih.gov/pubmed/31339866
  18. Lauren F Collins, Anandi N Sheth, C Christina Mehta, Elizabeth T Golub, Phyllis C Tien, Kathryn Anastos, Audrey L French, Seble Kassaye, Tonya Taylor, Mirjam-Colette Kempf, Margaret A Fischl, Adaora A Adimora, Frank J Palella, Igho Ofotokun. 977. The Prevalence and Burden of Non-AIDS Co-Morbidities in Women with or At-risk for HIV Infection in the United States. Open Forum Infectious Diseases. 2019 Oct 23; 6(Supplement_2):s36-s36.
  19. S. Moron-Lopez, G. Xie, P. Kim, J. Wong, J. Price, N. Elnachef, R. Greenblatt, P. Tien, N. Roan, S. Yukl. OP 7.6 Tissue-specific differences in the mechanisms that govern HIV latency in blood, liver, gut and genital tract in ART-suppressed women. Journal of virus eradication. 2019 Dec 1; 5:40.
    http://www.ncbi.nlm.nih.gov/pubmed/30615096
  20. Whittle HJ, Leddy AM, Shieh J, Tien PC, Ofotokun I, Adimora AA, Turan JM, Frongillo EA, Turan B, Weiser SD. Precarity and health: Theorizing the intersection of multiple material-need insecurities, stigma, and illness among women in the United States. Soc Sci Med. 2020 01; 245:112683.
    http://www.ncbi.nlm.nih.gov/pubmed/31127819
  21. Leddy AM, Turan JM, Johnson MO, Neilands TB, Kempf MC, Konkle-Parker D, Wingood G, Tien PC, Wilson TE, Logie CH, Weiser SD, Turan B. Poverty stigma is associated with suboptimal HIV care and treatment outcomes among women living with HIV in the United States. AIDS. 2019 07 01; 33(8):1379-1384.
    http://www.ncbi.nlm.nih.gov/pubmed/30870197
  22. Reid MJA, Ma Y, Golovaty I, Okello S, Sentongo R, Feng M, Tsai AC, Kakuhikire B, Tracy R, Hunt PW, Siedner M, Tien PC. Association of Gut Intestinal Integrity and Inflammation with Insulin Resistance in Adults Living with HIV in Uganda. AIDS Patient Care STDS. 2019 07; 33(7):299-307.
    http://www.ncbi.nlm.nih.gov/pubmed/31188016
  23. Womack JA, Murphy TE, Rentsch CT, Tate JP, Bathulapalli H, Smith AC, Bates J, Jarad S, Gibert CL, Rodriguez-Barradas MC, Tien PC, Yin MT, Gill TM, Friedlaender G, Brandt CA, Justice AC. Polypharmacy, Hazardous Alcohol and Illicit Substance Use, and Serious Falls Among PLWH and Uninfected Comparators. J Acquir Immune Defic Syndr. 2019 11 01; 82(3):305-313.
    http://www.ncbi.nlm.nih.gov/pubmed/31304190
  24. Crockett KB, Edmonds A, Johnson MO, Neilands TB, Kempf MC, Konkle-Parker D, Wingood G, Tien PC, Cohen M, Wilson TE, Logie CH, Sosanya O, Plankey M, Golub E, Adimora AA, Parish C, Weiser SD, Turan JM, Turan B. Neighborhood Racial Diversity, Socioeconomic Status, and Perceptions of HIV-Related Discrimination and Internalized HIV Stigma Among Women Living with HIV in the United States. AIDS Patient Care STDS. 2019 06; 33(6):270-281.
    http://www.ncbi.nlm.nih.gov/pubmed/31166786
  25. Jacqueline Shieh, Sheri Weiser, Henry Whittle, Ighovwerha Ofotokun, Adaora Adimora, Phyllis Tien, Anna Leddy. Perceived Neighborhood-level Drivers of Food Insecurity Among Aging Women in the United States (P04-155-19). Current Developments in Nutrition. 2019 Jun 1; 3(Supplement_1).