Craig Cohen, MD, MPH

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Craig Cohen, MD, MPH

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Director, CFAR International Program
Professor, School of Medicine
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Biography

Craig Cohen, MD, MPH, is a Professor in the UCSF Department of Obstetrics, Gynecology and Reproductive Sciences, an Attending Physician at San Francisco General Hospital and co-Director of the University of California Global Health Institute (UCGHI: www.ucghi.universityofcalifornia.edu). He conducts clinical and implementation research in two major areas: HIV and sexually transmitted infection prevention and HIV/AIDS care and support in developing countries including the development of live biotherapeutic products to prevent bacterial vaginosis and HIV acquisition in women. In 1994, Dr. Cohen and his colleague Dr. Elizabeth Bukusi at the Kenya Medical Research Institute (KEMRI) established the Research Care and Treatment Program (RCTP) a collaboration with projects in Nairobi and Kisumu, Kenya. In addition to conducting research, the goal of the program is to enhance local capacity to conduct biomedical research through training and infrastructure development. RCTP employs over 700 full-time staff in Kenya including epidemiologists, physicians, nurse-counselors, laboratory technologists, field workers, data managers, biostatisticians and administrative staff. Dr. Cohen is the Founding Director of the Family AIDS Care and Education Services (FACES: www.faces-kenya.org) since its creation in 2004. FACES is a CDC/PEPFAR-funded HIV/AIDS care and treatment program in Western Kenya and supports the Ministry of Health to care for ~50,000 persons living with HIV. As part of FACES, Dr. Cohen has also developed the Student Training Elective Program (STEP), which allows medical students and residents to do research and clinical electives at FACES sites. Additionally, Dr. Cohen directs the UCSF Reproductive Infectious Disease (RID) Fellowship, which aims to provide Ob/Gyn and post-doctoral trainees with the tools and experience necessary to develop into independent investigators and launch productive careers in the field of RID. He also co-directs the newly established University of California Global Health Institute (UCGHI) GloCal Health Fellowship which train fellows in global health research between in collaboration with 20 international collaborating institutions. Overall, Dr. Cohen has directly mentored more than 70 doctoral/professional students, residents and post-doctoral fellows, most of who have conducted research in Kenya. Areas of Interest: •Prevention of HIV and sexually transmitted infections (STI) •Microbicides, live biotherapeutic products to prevent HIV/STI *Integration of reproductive health and HIV services •Improvement of care to HIV infected persons living in resource poor settings *Multisectoral interventions to improve the lives of families affected by HIV •Research training and infrastructure development in developing countries
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  1. Bukusi EA, Steele M, Cohen CR, Nguti R, Maingi CW, Thomas KK, Holmes KK. Safety, acceptability, and tolerability of 3 topical microbicides among heterosexual Kenyan men. . 2007 Apr 01; 44(4):423-8.
  2. Coleman JS, Hitti J, Bukusi EA, Mwachari C, Muliro A, Nguti R, Gausman R, Jensen S, Patton D, Lockhart D, Coombs R, Cohen CR. Infectious correlates of HIV-1 shedding in the female upper and lower genital tracts. AIDS. 2007 Mar 30; 21(6):755-9.
  3. Steele MS, Bukusi E, Cohen CR, Shell-Duncan BA, Holmes KK. The ABCs of HIV prevention in men: associations with HIV risk and protective behaviors. . 2006 Dec 15; 43(5):571-6.
  4. Sharma A, Bukusi E, Posner S, Feldman D, Ngugi E, Cohen CR. Sex preparation and diaphragm acceptability in sex work in Nairobi, Kenya. Sex Health. 2006 Dec; 3(4):261-8.
  5. Meier AS, Bukusi EA, Cohen CR, Holmes KK. Independent association of hygiene, socioeconomic status, and circumcision with reduced risk of HIV infection among Kenyan men. . 2006 Sep; 43(1):117-8.
  6. Iverson-Cabral SL, Astete SG, Cohen CR, Rocha EP, Totten PA. Intrastrain heterogeneity of the mgpB gene in Mycoplasma genitalium is extensive in vitro and in vivo and suggests that variation is generated via recombination with repetitive chromosomal sequences. Infect Immun. 2006 Jul; 74(7):3715-26.
  7. Bukusi EA, Cohen CR, Meier AS, Waiyaki PG, Nguti R, Njeri JN, Holmes KK. Bacterial vaginosis: risk factors among Kenyan women and their male partners. Sex Transm Dis. 2006 Jun; 33(6):361-7.
  8. Mwachari CW, Nduba VN, Park DR, Meier AS, Kariuki JN, Muyodi JA, Karimi F, Kigo A, Holmes KK, Cohen CR. Clinical presentation among HIV-infected and non-infected adults with community acquired pneumonia in Nairobi. Int J Tuberc Lung Dis. 2006 May; 10(5):516-22.
  9. Mugo NR, Kiehlbauch JA, Nguti R, Meier A, Gichuhi JW, Stamm WE, Cohen CR. Effect of human immunodeficiency virus-1 infection on treatment outcome of acute salpingitis. Obstet Gynecol. 2006 Apr; 107(4):807-12.
  10. Cohen CR, Mugo NR, Astete SG, Odondo R, Manhart LE, Kiehlbauch JA, Stamm WE, Waiyaki PG, Totten PA. Detection of Mycoplasma genitalium in women with laparoscopically diagnosed acute salpingitis. Sex Transm Infect. 2005 Dec; 81(6):463-6.
  11. Cohen CR, Koochesfahani KM, Meier AS, Shen C, Karunakaran K, Ondondo B, Kinyari T, Mugo NR, Nguti R, Brunham RC. Immunoepidemiologic profile of Chlamydia trachomatis infection: importance of heat-shock protein 60 and interferon- gamma. J Infect Dis. 2005 Aug 15; 192(4):591-9.
  12. Baeten JM, Lavreys L, Sagar M, Kreiss JK, Richardson BA, Chohan B, Panteleeff D, Mandaliya K, Ndinya-Achola JO, Overbaugh J, Farley T, Mwachari C, Cohen C, Chipato T, Jaisamrarn U, Kiriwat O, Duerr A. Effect of contraceptive methods on natural history of HIV: studies from the Mombasa cohort. . 2005 Mar; 38 Suppl 1:S18-21.
  13. Steele MS, Bukusi E, Cohen CR, Shell-Duncan BA, Holmes KK. Male genital hygiene beliefs and practices in Nairobi, Kenya. Sex Transm Infect. 2004 Dec; 80(6):471-6.
  14. Hebb JK, Cohen CR, Astete SG, Bukusi EA, Totten PA. Detection of novel organisms associated with salpingitis, by use of 16S rDNA polymerase chain reaction. J Infect Dis. 2004 Dec 15; 190(12):2109-20.
  15. Mwachari CW, Shepherd BE, Cleopa O, Odhiambo JA, Cohen CR. Mortality and burden of disease in a cohort of HIV-seropositive adults in Nairobi, Kenya. Int J STD AIDS. 2004 Feb; 15(2):120-6.
  16. Criniti A, Mwachari CW, Meier AS, Nduba V, Sanguli L, Ngumo JK, Cohen CR. Association of hormonal contraception and HIV-seroprevalence in Nairobi, Kenya. AIDS. 2003 Dec 05; 17(18):2667-9.
  17. Mwachari CW, Meier AS, Muyodi J, Gatei W, Waiyaki P, Cohen CR. Chronic diarrhoea in HIV-1-infected adults in Nairobi, Kenya: evaluation of risk factors and the WHO treatment algorithm. AIDS. 2003 Sep 26; 17(14):2124-6.
  18. Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Immunogenetic correlates for Chlamydia trachomatis-associated tubal infertility. Obstet Gynecol. 2003 Mar; 101(3):438-44.
  19. Penner J, Meier AS, Mwachari C, Ayuka F, Muchina B, Odhiambo J, Cohen CR. Risk factors for pneumonia in urban-dwelling HIV-infected women: a case-control study in Nairobi, Kenya. . 2003 Feb 01; 32(2):223-8.
  20. Cohen CR, Gravelle L, Symekher S, Waiyaki P, Stamm WE, Kiehlbauch JA. Etiology of persistent tubo-ovarian abscess in Nairobi, Kenya. Infect Dis Obstet Gynecol. 2003; 11(1):45-51.
  21. Cohen CR, Manhart LE, Bukusi EA, Astete S, Brunham RC, Holmes KK, Sinei SK, Bwayo JJ, Totten PA. Association between Mycoplasma genitalium and acute endometritis. Lancet. 2002 Mar 02; 359(9308):765-6.
  22. Mwachari CW, Cohen CR, Meier AS, Nganga LW, Kimari JN, Odhiambo JA. Respiratory tract infection in HIV-1-infected adults in Nairobi, Kenya: evaluation of risk factors and the world health organization treatment algorithm. . 2001 Aug 01; 27(4):365-71.
  23. Cohen CR, Nguti R, Bukusi EA, Lu H, Shen C, Luo M, Sinei S, Plummer F, Bwayo J, Brunham RC. Human immunodeficiency virus type 1-infected women exhibit reduced interferon-gamma secretion after Chlamydia trachomatis stimulation of peripheral blood lymphocytes. J Infect Dis. 2000 Dec; 182(6):1672-7.
  24. Bukusi EA, Cohen CR, Stevens CE, Sinei S, Reilly M, Grieco V, Eschenbach DA, Holmes KK, Bwayo J, Ndinya-Achola JO, Kreiss J. Effects of human immunodeficiency virus 1 infection on microbial origins of pelvic inflammatory disease and on efficacy of ambulatory oral therapy. Am J Obstet Gynecol. 1999 Dec; 181(6):1374-81.
  25. Cohen CR, Plummer FA, Mugo N, Maclean I, Shen C, Bukusi EA, Irungu E, Sinei S, Bwayo J, Brunham RC. Increased interleukin-10 in the the endocervical secretions of women with non-ulcerative sexually transmitted diseases: a mechanism for enhanced HIV-1 transmission? AIDS. 1999 Feb 25; 13(3):327-32.