Craig Cohen, MD, MPH

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Craig Cohen, MD, MPH

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Director, CFAR International Program
Professor, School of Medicine
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Biography

Craig Cohen, MD, MPH, is a Professor in the UCSF Department of Obstetrics, Gynecology and Reproductive Sciences, an Attending Physician at San Francisco General Hospital and co-Director of the University of California Global Health Institute (UCGHI: www.ucghi.universityofcalifornia.edu). He conducts clinical and implementation research in two major areas: HIV and sexually transmitted infection prevention and HIV/AIDS care and support in developing countries including the development of live biotherapeutic products to prevent bacterial vaginosis and HIV acquisition in women. In 1994, Dr. Cohen and his colleague Dr. Elizabeth Bukusi at the Kenya Medical Research Institute (KEMRI) established the Research Care and Treatment Program (RCTP) a collaboration with projects in Nairobi and Kisumu, Kenya. In addition to conducting research, the goal of the program is to enhance local capacity to conduct biomedical research through training and infrastructure development. RCTP employs over 700 full-time staff in Kenya including epidemiologists, physicians, nurse-counselors, laboratory technologists, field workers, data managers, biostatisticians and administrative staff. Dr. Cohen is the Founding Director of the Family AIDS Care and Education Services (FACES: www.faces-kenya.org) since its creation in 2004. FACES is a CDC/PEPFAR-funded HIV/AIDS care and treatment program in Western Kenya and supports the Ministry of Health to care for ~50,000 persons living with HIV. As part of FACES, Dr. Cohen has also developed the Student Training Elective Program (STEP), which allows medical students and residents to do research and clinical electives at FACES sites. Additionally, Dr. Cohen directs the UCSF Reproductive Infectious Disease (RID) Fellowship, which aims to provide Ob/Gyn and post-doctoral trainees with the tools and experience necessary to develop into independent investigators and launch productive careers in the field of RID. He also co-directs the newly established University of California Global Health Institute (UCGHI) GloCal Health Fellowship which train fellows in global health research between in collaboration with 20 international collaborating institutions. Overall, Dr. Cohen has directly mentored more than 70 doctoral/professional students, residents and post-doctoral fellows, most of who have conducted research in Kenya. Areas of Interest: •Prevention of HIV and sexually transmitted infections (STI) •Microbicides, live biotherapeutic products to prevent HIV/STI *Integration of reproductive health and HIV services •Improvement of care to HIV infected persons living in resource poor settings *Multisectoral interventions to improve the lives of families affected by HIV •Research training and infrastructure development in developing countries
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  1. Hemmerling A, Harrison W, Schroeder A, Park J, Korn A, Shiboski S, Foster-Rosales A, Cohen CR. Phase 2a study assessing colonization efficiency, safety, and acceptability of Lactobacillus crispatus CTV-05 in women with bacterial vaginosis. Sex Transm Dis. 2010 Dec; 37(12):745-50.
  2. Cohen CR, Moscicki AB, Scott ME, Ma Y, Shiboski S, Bukusi E, Daud I, Rebbapragada A, Brown J, Kaul R. Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa. AIDS. 2010 Aug 24; 24(13):2069-74.
  3. Kwena ZA, Cohen CR, Sang NM, Ng'ayo MO, Ochieng JH, Bukusi EA. Fishermen as a Suitable Population for HIV Intervention Trials. AIDS Res Treat. 2010; 2010:865903.
  4. Rahangdale L, Banandur P, Sreenivas A, Turan JM, Washington R, Cohen CR. Stigma as experienced by women accessing prevention of parent-to-child transmission of HIV services in Karnataka, India. AIDS Care. 2010 Jul; 22(7):836-42.
  5. Donnell D, Baeten JM, Kiarie J, Thomas KK, Stevens W, Cohen CR, McIntyre J, Lingappa JR, Celum C, Partners in Prevention HSV/HIV Transmission Study Team . Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis. Lancet. 2010 Jun 12; 375(9731):2092-8.
  6. Pandit JA, Sirotin N, Tittle R, Onjolo E, Bukusi EA, Cohen CR. Shamba Maisha: a pilot study assessing impacts of a micro-irrigation intervention on the health and economic wellbeing of HIV patients. BMC Public Health. 2010 May 11; 10:245.
  7. Lingappa JR, Baeten JM, Wald A, Hughes JP, Thomas KK, Mujugira A, Mugo N, Bukusi EA, Cohen CR, Katabira E, Ronald A, Kiarie J, Farquhar C, Stewart GJ, Makhema J, Essex M, Were E, Fife KH, de Bruyn G, Gray GE, McIntyre JA, Manongi R, Kapiga S, Coetzee D, Allen S, Inambao M, Kayitenkore K, Karita E, Kanweka W, Delany S, Rees H, Vwalika B, Magaret AS, Wang RS, Kidoguchi L, Barnes L, Ridzon R, Corey L, Celum C, Partners in Prevention HSV/HIV Transmission Study Team . Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial. Lancet. 2010 Mar 06; 375(9717):824-33.
  8. Celum C, Wald A, Lingappa JR, Magaret AS, Wang RS, Mugo N, Mujugira A, Baeten JM, Mullins JI, Hughes JP, Bukusi EA, Cohen CR, Katabira E, Ronald A, Kiarie J, Farquhar C, Stewart GJ, Makhema J, Essex M, Were E, Fife KH, de Bruyn G, Gray GE, McIntyre JA, Manongi R, Kapiga S, Coetzee D, Allen S, Inambao M, Kayitenkore K, Karita E, Kanweka W, Delany S, Rees H, Vwalika B, Stevens W, Campbell MS, Thomas KK, Coombs RW, Morrow R, Whittington WL, McElrath MJ, Barnes L, Ridzon R, Corey L, Partners in Prevention HSV/HIV Transmission Study Team . Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2. N Engl J Med. 2010 Feb 04; 362(5):427-39.
  9. Matu MN, Orinda GO, Njagi EN, Cohen CR, Bukusi EA. In vitro inhibitory activity of human vaginal lactobacilli against pathogenic bacteria associated with bacterial vaginosis in Kenyan women. Anaerobe. 2010 Jun; 16(3):210-5.
  10. Hemmerling A, Harrison W, Schroeder A, Park J, Korn A, Shiboski S, Cohen CR. Phase 1 dose-ranging safety trial of Lactobacillus crispatus CTV-05 for the prevention of bacterial vaginosis. Sex Transm Dis. 2009 Sep; 36(9):564-9.
  11. Ondondo BO, Brunham RC, Harrison WG, Kinyari T, Sheth PM, Mugo NR, Cohen CR. Frequency and magnitude of Chlamydia trachomatis elementary body- and heat shock protein 60-stimulated interferon gamma responses in peripheral blood mononuclear cells and endometrial biopsy samples from women with high exposure to infection. J Infect Dis. 2009 Jun 15; 199(12):1771-9.
  12. Lingappa JR, Kahle E, Mugo N, Mujugira A, Magaret A, Baeten J, Bukusi EA, Cohen CR, Katabira E, Ronald A, Kiarie J, Farquhar C, Stewart GJ, Makhema J, Essex M, Were E, Fife K, Debruyn G, Gray G, McIntyre J, Manongi R, Kapiga S, Coetzee D, Allen S, Inambao M, Kayitenkore K, Karita E, Kanweka W, Delany S, Rees H, Vwalika B, Coombs RW, Morrow R, Whittington W, Corey L, Wald A, Celum C, Partners HSV-2/HIV-1 Transmission Study Team . Characteristics of HIV-1 discordant couples enrolled in a trial of HSV-2 suppression to reduce HIV-1 transmission: the partners study. PLoS One. 2009; 4(4):e5272.
  13. Cohen CR, Montandon M, Carrico AW, Shiboski S, Bostrom A, Obure A, Kwena Z, Bailey RC, Nguti R, Bukusi EA. Association of attitudes and beliefs towards antiretroviral therapy with HIV-seroprevalence in the general population of Kisumu, Kenya. PLoS One. 2009; 4(3):e4573.
  14. Montandon M, Sahin-Hodoglugil NN, Bukusi E, Agot K, Boland B, Cohen CR. Sexuality, HIV risk and potential acceptability of involving adolescent girls in microbicide research in Kisumu, Kenya. Sex Health. 2008 Dec; 5(4):339-46.
  15. Turan JM, Bukusi EA, Cohen CR, Sande J, Miller S. Effects of HIV/AIDS on maternity care providers in Kenya. J Obstet Gynecol Neonatal Nurs. 2008 Sep-Oct; 37(5):588-95.
  16. Turan JM, Miller S, Bukusi EA, Sande J, Cohen CR. HIV/AIDS and maternity care in Kenya: how fears of stigma and discrimination affect uptake and provision of labor and delivery services. AIDS Care. 2008 Sep; 20(8):938-45.
  17. Nduba VN, Mwachari CW, Magaret AS, Park DR, Kigo A, Hooton TM, Cohen CR. Placebo found equivalent to amoxicillin for treatment of acute bronchitis in Nairobi, Kenya: a triple blind, randomised, equivalence trial. Thorax. 2008 Nov; 63(11):999-1005.
  18. Madhivanan P, Krupp K, Chandrasekaran V, Karat C, Arun A, Cohen CR, Reingold AL, Klausner JD. Prevalence and correlates of bacterial vaginosis among young women of reproductive age in Mysore, India. Indian J Med Microbiol. 2008 Apr-Jun; 26(2):132-7.
  19. Sharma A, Bukusi E, Gorbach P, Cohen CR, Muga C, Kwena Z, Holmes KK. Sexual identity and risk of HIV/STI among men who have sex with men in Nairobi. Sex Transm Dis. 2008 Apr; 35(4):352-4.
  20. Bolton M, van der Straten A, Cohen CR. Probiotics: potential to prevent HIV and sexually transmitted infections in women. Sex Transm Dis. 2008 Mar; 35(3):214-25.
  21. Mwachari C, Nduba V, Nguti R, Park DR, Sanguli L, Cohen CR. Validation of a new clinical scoring system for acute bronchitis. Int J Tuberc Lung Dis. 2007 Nov; 11(11):1253-9.
  22. Iverson-Cabral SL, Astete SG, Cohen CR, Totten PA. mgpB and mgpC sequence diversity in Mycoplasma genitalium is generated by segmental reciprocal recombination with repetitive chromosomal sequences. Mol Microbiol. 2007 Oct; 66(1):55-73.
  23. Ngugi EN, Chakkalackal M, Sharma A, Bukusi E, Njoroge B, Kimani J, MacDonald KS, Bwayo JJ, Cohen CR, Moses S, Kaul R, Kibera HIV Study Group . Sustained changes in sexual behavior by female sex workers after completion of a randomized HIV prevention trial. . 2007 Aug 15; 45(5):588-94.
  24. Cohen CR, Nosek M, Meier A, Astete SG, Iverson-Cabral S, Mugo NR, Totten PA. Mycoplasma genitalium infection and persistence in a cohort of female sex workers in Nairobi, Kenya. Sex Transm Dis. 2007 May; 34(5):274-9.
  25. Becker ML, Cohen CR, Cheang M, Washington RG, Blanchard JF, Moses S. Diarrheal disease among HIV-infected adults in Karnataka, India: evaluation of risk factors and etiology. Am J Trop Med Hyg. 2007 Apr; 76(4):718-22.