The program initially aimed to provide antiretroviral treatment (ART) to 2 million HIV-infected people in resource-limited settings, to prevent 7 million new infections, and to support care for 10 million people by 2010. PEPFAR increased the number of Africans receiving ART from 50,000 at the start of the initiative in 2004 to at least 1.2 million in early 2008. PEPFAR has been called the largest health initiative ever initiated by one country to address a disease. The budget presented by President Bush for the fiscal year 2008 included a request for $5.4 billion for PEPFAR.

1 Awards

  • NIH/PEPFAR Collaboration for Implementation Sciences

    NIH/PEPFAR Collaboration for Implementation Sciences


    Tuberculosis (TB) is the leading killer of PLHIV globally, accounting for nearly a quarter of all deaths. To reduce the impact of TB, the WHO recommends intensified case finding (ICF) for all PLHIV (i.e., symptombased TB screening at every clinical encounter, followed by confirmatory testing of those who screen positive). However, ICF has been challenging to implement in sub-Saharan Africa because testing the 70- 90% of PLHIV who are symptom screen-positive for active TB is beyond the capacity of most HIV/AIDS programs.