Phyllis Tien, MD
Professor, School of Medicine
Email: ptien@medicine.ucsf.edu
Biography
Dr. Tien is Professor of Medicine at the University of California, San Francisco and Chief of the Infectious Diseases Division at the San Francisco Veterans Affairs Health Care System. Her research program examines the mechanisms by which chronic viral infections (specifically HIV and HCV) and their associated metabolic and immune perturbations impact long term organ injury in adults. She has served in several leadership positions including Co-Chair of the Executive Committee of the Multicenter AIDS Cohort Study (MACS)/Women's Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS) and the MWCCS Steering Committee. The MWCCS integrates two of the largest and longest running NIH-funded prospective cohorts of adult men and women with and at risk for HIV in the U.S. She also serves as Chair of the Inter-CFAR Collaboration on HIV Research in Women and previously served as Chair of the NIH AIDS Clinical Epidemiology Study Section. She was a member of the Department of Health and Human Services Antiretroviral Guidelines Panel, and is currently a member of the NIAID AIDS Research Study Section and the NIH COVID-19 Treatment Guidelines Panel.
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- Moron-Lopez S, Xie G, Kim P, Siegel DA, Lee S, Wong JK, Price JC, Elnachef N, Greenblatt RM, Tien PC, Roan NR, Yukl SA. Tissue-specific differences in HIV DNA levels and mechanisms that govern HIV transcription in blood, gut, genital tract and liver in ART-treated women. J Int AIDS Soc. 2021 Jul; 24(7):e25738.
- Kuriakose S, Singh K, Pau AK, Daar E, Gandhi R, Tebas P, Evans L, Gulick RM, Lane HC, Masur H, NIH COVID-19 Treatment Guidelines Panel , Aberg JA, Adimora AA, Baker J, Kreuziger LB, Bedimo R, Belperio PS, Cantrill SV, Coopersmith CM, Davis SL, Dzierba AL, Gallagher JJ, Glidden DV, Grund B, Hardy EJ, Hinkson C, Hughes BL, Johnson S, Keller MJ, Kim AY, Lennox JL, Levy MM, Li JZ, Martin GS, Naggie S, Pavia AT, Seam N, Simpson SQ, Swindells S, Tien P, Waghmare AA, Wilson KC, Yazdany J, Zachariah P, Campbell DM, Harrison C, Burgess T, Francis J, Sheikh V, Uyeki TM, Walker R, Brooks JT, Ortiz LB, Davey RT, Doepel LK, Eisinger RW, Han A, Higgs ES, Nason MC, Crew P, Lerner AM, Lund C, Worthington C. Developing Treatment Guidelines During a Pandemic Health Crisis: Lessons Learned From COVID-19. Ann Intern Med. 2021 08; 174(8):1151-1158.
- Haley DF, Edmonds A, Ramirez C, French AL, Tien P, Thio CL, Witt MD, Seaberg EC, Plankey MW, Cohen MH, Adimora AA. Direct-Acting Antiviral Hepatitis C Treatment Cascade and Barriers to Treatment Initiation Among US Men and Women With and Without HIV. J Infect Dis. 2021 Jun 15; 223(12):2136-2144.
- Tan JY, Sheira LA, Frongillo EA, Gustafson D, Sharma A, Merenstein D, Cohen MH, Golub E, Edmonds A, Ofotokun I, Fischl M, Konkle-Parker D, Neilands T, Tien P, Weiser SD. Food insecurity and frailty among women with and without HIV in the United States: a cross-sectional analysis. J Int AIDS Soc. 2021 06; 24(6):e25751.
- Sharma A, Hoover DR, Shi Q, Gustafson DR, Plankey M, Tien PC, Weber KM, Vance DE, Floris-Moore M, Bolivar HH, Golub ET, Holstad MM, Yin MT. High Frequency of Recurrent Falls Among Prefrail and Frail Women With and Without HIV. J Acquir Immune Defic Syndr. 2021 06 01; 87(2):842-850.
- Leddy AM, Zakaras JM, Shieh J, Conroy AA, Ofotokun I, Tien PC, Weiser SD. Intersections of food insecurity, violence, poor mental health and substance use among US women living with and at risk for HIV: Evidence of a syndemic in need of attention. PLoS One. 2021; 16(5):e0252338.
- Anandi N. Sheth, Adaora A. Adimora, Elizabeth Topper Golub, Seble G. Kassaye, Aadia Rana, Daniel Westreich, Jennifer Webster Cyriaque, Carrigan Parish, Deborah Konkle-Parker, Deborah L. Jones, Mirjam-Colette Kempf, Igho Ofotokun, Ruth M. Kanthula, Jessica Donahue, Patricia Raccamarich, Tina Tisdale, Catalina Ramirez, Lari Warren-Jeanpiere, Phyllis C. Tien, Maria L. Alcaide. Study of Treatment and Reproductive Outcomes (STAR): A Protocol for a Longitudinal Cohort Study of HIV Infection and Treatment among Women of Reproductive Age in the Southern United States (Preprint). JMIR Research Protocols. 2021 May 12.
- Collins LF, Sheth AN, Mehta CC, Naggie S, Golub ET, Anastos K, French AL, Kassaye S, Taylor T, Fischl MA, Adimora AA, Kempf MC, Palella FJ, Tien PC, Ofotokun I. The Prevalence and Burden of Non-AIDS Comorbidities Among Women Living With or at Risk for Human Immunodeficiency Virus Infection in the United States. Clin Infect Dis. 2021 04 26; 72(8):1301-1311.
- Olali AZ, Sharma A, Shi Q, Hoover DR, Weber KM, French AL, McKay HS, Tien PC, Al-Harthi L, Yin MT, Ross RD. Change in Circulating Undercarboxylated Osteocalcin (ucOCN) Is Associated With Fat Accumulation in HIV-Seropositive Women. J Acquir Immune Defic Syndr. 2021 04 15; 86(5):e139-e145.
- Galaviz KI, Schneider MF, Tien PC, Althoff KN, Ali MK, Ofotokun I, Brown TT. Expanding the Finnish Diabetes Risk Score for Predicting Diabetes Incidence in People Living with HIV. AIDS Res Hum Retroviruses. 2021 05; 37(5):373-379.
- Ehinger E, Ghosheh Y, Pramod AB, Lin J, Hanna DB, Mueller K, Durant CP, Baas L, Qi Q, Wang T, Buscher K, Anastos K, Lazar JM, Mack WJ, Tien PC, Cohen MH, Ofotokun I, Gange S, Heath SL, Hodis HN, Tracy RP, Landay AL, Kaplan RC, Ley K. Classical monocyte transcriptomes reveal significant anti-inflammatory statin effect in women with chronic HIV. Cardiovasc Res. 2021 03 21; 117(4):1166-1177.
- Peters BA, Sheira LA, Hanna DB, Qi Q, Sharma A, Adedimeji A, Wilson T, Merenstein D, Tien PC, Cohen M, Wentz EL, Kinslow J, Landay AL, Weiser SD. Food Insecurity and T-cell Dysregulation in Women Living With Human Immunodeficiency Virus on Antiretroviral Therapy. Clin Infect Dis. 2021 03 01; 72(5):e112-e119.
- Shieh JA, Leddy AM, Whittle HJ, Ofotokun I, Adimora AA, Tien PC, Weiser SD. Perceived Neighborhood-Level Drivers of Food Insecurity Among Aging Women in the United States: A Qualitative Study. J Acad Nutr Diet. 2021 05; 121(5):844-853.
- Chow FC, Ma Y, Manion M, Rupert A, Lambert-Messerlian G, Bushnell CD, Cedars MI, Sereti I, Sorond FA, Hsue PY, Tien PC. Factors associated with worse cerebrovascular function in aging women with and at risk for HIV. AIDS. 2021 02 02; 35(2):257-266.
- Lahiri CD, Xu Y, Wang K, Alvarez JA, Sheth AN, O'Halloran J, Spence AB, Tien P, Gustafson DR, Milam J, Fischl MA, Konkle-Parker D, Adimora AA, Sharma A, Weber KM, Ofotokun I, Rubin LH. Weight and Body Mass Index Change After Switching to Integrase Inhibitors or Tenofovir Alafenamide Among Women Living with HIV. AIDS Res Hum Retroviruses. 2021 06; 37(6):461-467.
- Crockett KB, Esensoy TA, Johnson MO, Neilands TB, Kempf MC, Konkle-Parker D, Wingood G, Tien PC, Cohen M, Wilson TE, Logie CH, Sosanya O, Plankey M, Golub E, Adimora AA, Parish C, D Weiser S, Turan JM, Turan B. Internalized HIV Stigma and Pain among Women with HIV in the United States: The Mediating Role of Depressive Symptoms. AIDS Behav. 2020 Dec; 24(12):3482-3490.
- Crockett KB, Esensoy TA, Johnson MO, Neilands TB, Kempf MC, Konkle-Parker D, Wingood G, Tien PC, Cohen M, Wilson TE, Logie CH, Sosanya O, Plankey M, Golub E, Adimora AA, Parish C, D Weiser S, Turan JM, Turan B. Internalized HIV Stigma and Pain among Women with HIV in the United States: The Mediating Role of Depressive Symptoms. AIDS Behav. 2020 Dec; 24(12):3482-3490.
- Emily R Cedarbaum, Yifei Ma, Rebecca Scherzer, Adaora A Adimora, Marcas Bamman, Mardge Cohen, Margaret A Fischl, Deborah R Gustafson, Kunihiro Matsushita, Igho Ofotokun, Michael Plankey, Eric C Seaberg, Anjali Sharma, Phyllis C Tien. Abstract 14374: Peripheral Artery Disease and Gait Speed in Women With and at Risk for HIV. Circulation. 2020 Nov 17; 142(Suppl_3).
- D'Souza G, Springer G, Gustafson D, Kassaye S, Alcaide ML, Ramirez C, Sharma A, Palella FJ, Tien PC, Detels R, Kempf MC, Lahiri CD, Rinaldo CR, French AL, Margolick JB, Adimora AA. COVID-19 symptoms and SARS-CoV-2 infection among people living with HIV in the US: the MACS/WIHS combined cohort study. HIV Res Clin Pract. 2020 10; 21(5):130-139.
- Sun J, Brown TT, Tong W, Samuels D, Tien P, Aissani B, Aouizerat B, Villacres M, Kuniholm MH, Gustafson D, Michel K, Cohen M, Schneider M, Adimora AA, Ali MK, Bolivar H, Hulgan T. African Mitochondrial DNA Haplogroup L2 Is Associated With Slower Decline of β-cell Function and Lower Incidence of Diabetes Mellitus in Non-Hispanic, Black Women Living With Human Immunodeficiency Virus. Clin Infect Dis. 2020 11 05; 71(8):e218-e225.
- Tan JY, A Sheira L, Frongillo EA, A Adimora A, Tien PC, Konkle-Parker D, Golub ET, Merenstein D, Levin S, Cohen M, Ofotokun I, A Fischl M, Rubin LH, Weiser SD. Food insecurity and neurocognitive function among women living with or at risk for HIV in the United States. Am J Clin Nutr. 2020 11 11; 112(5):1280-1286.
- Sun J, Brown TT, Tong W, Samuels D, Tien P, Aissani B, Aouizerat B, Villacres M, Kuniholm MH, Gustafson D, Michel K, Cohen M, Schneider M, Adimora AA, Ali MK, Bolivar H, Hulgan T. African Mitochondrial DNA Haplogroup L2 Is Associated With Slower Decline of β-cell Function and Lower Incidence of Diabetes Mellitus in Non-Hispanic, Black Women Living With Human Immunodeficiency Virus. Clin Infect Dis. 2020 11 05; 71(8):e218-e225.
- Weiser SD, Sheira LA, Palar K, Kushel M, Wilson TE, Adedimeji A, Merenstein D, Cohen M, Turan JM, Metsch L, Adimora AA, Ofotokun I, Wentz E, Tien PC, Frongillo EA. Mechanisms from Food Insecurity to Worse HIV Treatment Outcomes in US Women Living with HIV. AIDS Patient Care STDS. 2020 10; 34(10):425-435.
- Erlandson KM, Travison TG, Zhu H, Magaziner J, Correa-de-Araujo R, Cawthon PM, Bhasin S, Manini T, Fielding RA, Palella FJ, Kingsley L, Lake JE, Sharma A, Tien PC, Weber KM, Yin MT, Brown TT. Application of Selected Muscle Strength and Body Mass Cut Points for the Diagnosis of Sarcopenia in Men and Women With or at Risk for HIV Infection. J Gerontol A Biol Sci Med Sci. 2020 06 18; 75(7):1338-1345.
- Kamkwalala AR, Wang X, Maki PM, Williams DW, Valcour VG, Damron A, Tien PC, Weber KM, Cohen MH, Sundermann EE, Meyer VJ, Little DM, Xu Y, Rubin LH. Brief Report: Higher Peripheral Monocyte Activation Markers Are Associated With Smaller Frontal and Temporal Cortical Volumes in Women With HIV. J Acquir Immune Defic Syndr. 2020 05 01; 84(1):54-59.