Immune-Based Strategies for HIV Cure Research

Suppressive antiretroviral therapy has been successful in control HIV-associated disease. However, the need for long-term patient care makes elimination of the latent HIV reservoir from the body a highly desirable goal. Studying the latent reservoir has been hampered by the low frequency of latently infected cells, the presence of these cells in diverse human tissues that are difficult to sample, and our fundamental lack of understanding of the cell types in which latent HIV can reside.