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Roland Krug, PhD
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Associate Professor, School of Medicine
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Email: roland.krug@ucsf.edu
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Biography
Roland Krug, PhD, has been at UCSF since 2003. Dr. Krug’s research interests include applying novel Magnetic Resonance Imaging and Spectroscopy tools to advance diagnosis of several musculoskeletal conditions with the ultimate goal to improve the quality of life of patients. He has a strong focus on identifying mechanisms that are responsible for low back pain as well as using novel tools such as MR guided high intensity focused ultrasound to treat this condition.
As a principal investigator, Dr. Krug has received substantial support from NIH including two R01, and a UH2/UH3. He is also a director of an U19 grant from the HEAL initiative to fight opioid addiction with a volume of 30 Million USD. Dr. Krug has more than 70 peer-reviewed articles published in the highest ranking journals in the field and serves as a reviewer for more than 15 scientific journals. He reviews grants for NIH as well as the German, Austrian, Dutch, and British National Institutes. He also teaches a class on MR pulse programming in the departmental master program.
Expertise:
Musculoskeletal Imaging
Specialty:
Advanced pulse sequence development for high field MR imaging, MR spectroscopy and MRgFUS temperature assessment.
Professional Interests:
MRI of spine. High-resolution MRI of trabecular and cortical bone, MR fat quantification based on Dixon techniques, image analysis techniques of trabecular bone microstructure. ultra-short-TE (UTE) MRI of cartilage, bone, tendons and ligaments. High-intensity focused ultra-sound (HIFU) applications for bone ablation (temperature mapping of bone using UTE).
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Displaying 26 - 50 of 82
- Berg-Johansen B, Han M, Fields AJ, Liebenberg EC, Lim BJ, Larson PE, Gunduz-Demir C, Kazakia GJ, Krug R, Lotz JC. Cartilage Endplate Thickness Variation Measured by Ultrashort Echo-Time MRI Is Associated With Adjacent Disc Degeneration. Spine (Phila Pa 1976). 2018 05 15; 43(10):E592-E600.
- Jordan CD, Han M, Kondapavulur S, Vera DB, Neumann KD, Moore T, Stillson C, Krug R, Behr S, Seo Y, VanBrocklin HF, Larson PEZ, Wilson M, Martin AJ, Hetts SW. Quantification of 89 Zr-Iron oxide nanoparticle biodistribution using PET-MR and ultrashort TE sequences. J Magn Reson Imaging. 2018 12; 48(6):1717-1720.
- Kazakia GJ, Carballido-Gamio J, Lai A, Nardo L, Facchetti L, Pasco C, Zhang CA, Han M, Parrott AH, Tien P, Krug R. Trabecular bone microstructure is impaired in the proximal femur of human immunodeficiency virus-infected men with normal bone mineral density. Quant Imaging Med Surg. 2018 Feb; 8(1):5-13.
- Lansdown DA, Lee S, Sam C, Krug R, Feeley BT, Ma CB. A Prospective, Quantitative Evaluation of Fatty Infiltration Before and After Rotator Cuff Repair. Orthop J Sports Med. 2017 Jul; 5(7):2325967117718537.
- Karampinos DC, Ruschke S, Dieckmeyer M, Diefenbach M, Franz D, Gersing AS, Krug R, Baum T. Quantitative MRI and spectroscopy of bone marrow. J Magn Reson Imaging. 2018 02; 47(2):332-353.
- Bucknor MD, Ozhinsky E, Shah R, Krug R, Rieke V. Effect of Sonication Duration and Power on Ablation Depth During MR-Guided Focused Ultrasound of Bone. J Magn Reson Imaging. 2017 11; 46(5):1418-1422.
- Ozhinsky E, Han M, Bucknor M, Krug R, Rieke V. T2-based temperature monitoring in bone marrow for MR-guided focused ultrasound. J Ther Ultrasound. 2016; 4:26.
- Krug R, Do L, Rieke V, Wilson MW, Saeed M. Evaluation of MRI protocols for the assessment of lumbar facet joints after MR-guided focused ultrasound treatment. J Ther Ultrasound. 2016; 4:14.
- Saeed M, Krug R, Do L, Hetts SW, Wilson MW. Renal ablation using magnetic resonance-guided high intensity focused ultrasound: Magnetic resonance imaging and histopathology assessment. World J Radiol. 2016 Mar 28; 8(3):298-307.
- Nardo L, Carballido-Gamio J, Tang S, Lai A, Krug R. Quantitative assessment of morphology, T1ρ, and T2 of shoulder cartilage using MRI. Eur Radiol. 2016 Dec; 26(12):4656-4663.
- Larson PE, Han M, Krug R, Jakary A, Nelson SJ, Vigneron DB, Henry RG, McKinnon G, Kelley DA. Ultrashort echo time and zero echo time MRI at 7T. MAGMA. 2016 Jun; 29(3):359-70.
- Nardo L, Han M, Kretzschmar M, Guindani M, Koch K, Vail T, Krug R, Link TM. Erratum to: Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla. Skeletal Radiol. 2015 Nov; 44(11):1617.
- Han M, Rieke V, Scott SJ, Ozhinsky E, Salgaonkar VA, Jones PD, Larson PE, Diederich CJ, Krug R. Quantifying temperature-dependent T1 changes in cortical bone using ultrashort echo-time MRI. Magn Reson Med. 2015 Dec; 74(6):1548-55.
- Wyatt C, Guha A, Venkatachari A, Li X, Krug R, Kelley DE, Link T, Majumdar S. Improved differentiation between knees with cartilage lesions and controls using 7T relaxation time mapping. J Orthop Translat. 2015 Oct; 3(4):197-204.
- Saeed M, Van TA, Krug R, Hetts SW, Wilson MW. Cardiac MR imaging: current status and future direction. Cardiovasc Diagn Ther. 2015 Aug; 5(4):290-310.
- Nardo L, Han M, Kretzschmar M, Kretschmar M, Guindani M, Koch K, Vail T, Krug R, Link TM. Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla. Skeletal Radiol. 2015 Nov; 44(11):1609-16.
- Do L, Wilson MW, Krug R, Hetts SW, Saeed M. MRI monitoring of function, perfusion and viability in microembolized moderately ischemic myocardium. Int J Cardiovasc Imaging. 2015 Aug; 31(6):1179-90.
- Lee S, Lucas RM, Lansdown DA, Nardo L, Lai A, Link TM, Krug R, Ma CB. Magnetic resonance rotator cuff fat fraction and its relationship with tendon tear severity and subject characteristics. J Shoulder Elbow Surg. 2015 Sep; 24(9):1442-51.
- Kretzschmar M, Nardo L, Han MM, Heilmeier U, Sam C, Joseph GB, Koch KM, Krug R, Link TM. Metal artefact suppression at 3 T MRI: comparison of MAVRIC-SL with conventional fast spin echo sequences in patients with Hip joint arthroplasty. Eur Radiol. 2015 Aug; 25(8):2403-11.
- Gee CS, Nguyen JT, Marquez CJ, Heunis J, Lai A, Wyatt C, Han M, Kazakia G, Burghardt AJ, Karampinos DC, Carballido-Gamio J, Krug R. Validation of bone marrow fat quantification in the presence of trabecular bone using MRI. J Magn Reson Imaging. 2015 Aug; 42(2):539-44.
- Fields AJ, Han M, Krug R, Lotz JC. Cartilaginous end plates: Quantitative MR imaging with very short echo times-orientation dependence and correlation with biochemical composition. Radiology. 2015 Feb; 274(2):482-9.
- Han M, Chiba K, Banerjee S, Carballido-Gamio J, Krug R. Variable flip angle three-dimensional fast spin-echo sequence combined with outer volume suppression for imaging trabecular bone structure of the proximal femur. J Magn Reson Imaging. 2015 May; 41(5):1300-10.
- Liebl H, Heilmeier U, Lee S, Nardo L, Patsch J, Schuppert C, Han M, Rondak IC, Banerjee S, Koch K, Link TM, Krug R. In vitro assessment of knee MRI in the presence of metal implants comparing MAVRIC-SL and conventional fast spin echo sequences at 1.5 and 3 T field strength. J Magn Reson Imaging. 2015 May; 41(5):1291-9.
- Han M, Larson PE, Liu J, Krug R. Depiction of achilles tendon microstructure in vivo using high-resolution 3-dimensional ultrashort echo-time magnetic resonance imaging at 7 T. Invest Radiol. 2014 May; 49(5):339-45.
- Karampinos DC, Melkus G, Baum T, Bauer JS, Rummeny EJ, Krug R. Bone marrow fat quantification in the presence of trabecular bone: initial comparison between water-fat imaging and single-voxel MRS. Magn Reson Med. 2014 Mar; 71(3):1158-65.