Joel Palefsky, MD
Member, CFAR Scientific Council
Professor, School of Medicine
Email: joel.palefsky@ucsf.edu
Biography
Joel Palefsky, M.D., C.M., F.R.C.P.(C). Professor of Medicine and Infectious Diseases at the University of California San Francisco School of Medicine. He is an internationally recognized expert on the molecular biology, treatment, pathogenesis and natural history of anogenital human papillomavirus infections, particularly in the setting of HIV infection. He is the director of the world's first clinic devoted to prevention of anal cancer, the Anal Neoplasia Clinic Research and Education Center at the UCSF Cancer Center. He is the vice-chair of the National Cancer Institute (NCI)-supported AIDS Malignancy Consortium. He is the chair of the Anal Cancer /HSIL Outcomes Research (ANCHOR) Study, a national multi-site NIH study designed to determine whether treatment of anal cancer precursor lesions prevents the development of anal cancer and to identify biomarkers of progression. He is founder and past president of the International Anal Neoplasia Society and is past president of the International Papillomavirus Society. He is the founder and chairperson of the IPVS International HPV Awareness Campaign.
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- Moscicki AB, Darragh TM, Berry-Lawhorn JM, Roberts JM, Khan MJ, Boardman LA, Chiao E, Einstein MH, Goldstone SE, Jay N, Likes WM, Stier EA, Welton ML, Wiley DJ, Palefsky JM. Screening for Anal Cancer in Women. J Low Genit Tract Dis. 2015 Jul; 19(3 Suppl 1):S27-42.
- Prendes BL, Wang SJ, Groppo ER, Eisele DW, Palefsky JM. Oral human papillomavirus infection in men who have sex with men with anal squamous intraepithelial lesions. Head Neck. 2016 04; 38 Suppl 1:E399-405.
- Palefsky J, Berry M. Prevention of anal cancer -- can we do better? Dis Colon Rectum. 2015 May; 58(5):e76.
- Wang CJ, Palefsky JM. Human Papillomavirus (HPV) Infections and the Importance of HPV Vaccination. Curr Epidemiol Rep. 2015 Jun; 2(2):101-109.
- Gonzalez P, Hildesheim A, Herrero R, Katki H, Wacholder S, Porras C, Safaeian M, Jimenez S, Darragh TM, Cortes B, Befano B, Schiffman M, Carvajal L, Palefsky J, Schiller J, Ocampo R, Schussler J, Lowy D, Guillen D, Stoler MH, Quint W, Morales J, Avila C, Rodriguez AC, Kreimer AR. Rationale and design of a long term follow-up study of women who did and did not receive HPV 16/18 vaccination in Guanacaste, Costa Rica. Vaccine. 2015 Apr 27; 33(18):2141-51.
- Brickman C, Palefsky JM. Human papillomavirus in the HIV-infected host: epidemiology and pathogenesis in the antiretroviral era. Curr HIV/AIDS Rep. 2015 Mar; 12(1):6-15.
- Ortiz AP, Reyes JC, Palefsky J, Negrón J, Da Costa M, Vázquez M, Rivera AI, Matos TD, Rios-Olivares E, Tortolero G. Oral human papillomavirus infection among drug users in Puerto Rico. P R Health Sci J. 2014 Dec; 33(4):190-6.
- Massad LS, Xie X, Burk R, Keller MJ, Minkoff H, D'Souza G, Watts DH, Palefsky J, Young M, Levine AM, Cohen M, Strickler HD. Long-term cumulative detection of human papillomavirus among HIV seropositive women. AIDS. 2014 Nov 13; 28(17):2601-8.
- Torres-Ibarra L, Conde-Glez CJ, Salmerón J, Palefsky J, Hernández-Nevares P, Sánchez-Alemán MA, Magis-Rodríguez C, Lazcano-Ponce E. Risk factors for anal HPV-16/18 infection in Mexican HIV-infected men who have sex with men. Prev Med. 2014 Dec; 69:157-64.
- D'Souza G, Burk RD, Palefsky JM, Massad LS, Strickler HD. Cervical human papillomavirus testing to triage borderline abnormal pap tests in HIV-coinfected women. AIDS. 2014 Jul 17; 28(11):1696-8.
- Ghartey J, Kovacs A, Burk RD, Stewart Massad L, Minkoff H, Xie X, D'souza G, Xue X, Heather Watts D, Levine AM, Einstein MH, Colie C, Anastos K, Eltoum IE, Herold BC, Palefsky JM, Strickler HD. Genital tract HIV RNA levels and their associations with human papillomavirus infection and risk of cervical precancer. J Acquir Immune Defic Syndr. 2014 Jul 01; 66(3):316-23.
- Hernandez AL, Efird JT, Holly EA, Berry JM, Jay N, Palefsky JM. Incidence of and risk factors for type-specific anal human papillomavirus infection among HIV-positive MSM. AIDS. 2014 Jun 01; 28(9):1341-9.
- Zhang C, Park JS, Grce M, Hibbitts S, Palefsky JM, Konno R, Smith-McCune KK, Giovannelli L, Chu TY, Picconi MA, Piña-Sánchez P, Settheetham-Ishida W, Coutlée F, De Marco F, Woo YL, Ho WC, Wong MC, Chirenje MZ, Magure T, Moscicki AB, Sabol I, Fiander AN, Chen Z, Chan MC, Cheung TH, Burk RD, Chan PK. Geographical distribution and risk association of human papillomavirus genotype 52-variant lineages. J Infect Dis. 2014 Nov 15; 210(10):1600-4.
- Ortiz AP, Pérez-Irizarry J, Soto-Salgado M, Suárez E, Pérez N, Cruz M, Palefsky J, Tortolero-Luna G, Miranda S, Colón-López V. Human papillomavirus-related cancers among people living with AIDS in Puerto Rico. Prev Chronic Dis. 2014 May 15; 11:E80.
- Patel J, Salit IE, Berry MJ, de Pokomandy A, Nathan M, Fishman F, Palefsky J, Tinmouth J. Environmental scan of anal cancer screening practices: worldwide survey results. Cancer Med. 2014 Aug; 3(4):1052-61.
- Kojic EM, Kang M, Cespedes MS, Umbleja T, Godfrey C, Allen RT, Firnhaber C, Grinsztejn B, Palefsky JM, Webster-Cyriaque JY, Saah A, Aberg JA, Cu-Uvin S. Immunogenicity and safety of the quadrivalent human papillomavirus vaccine in HIV-1-infected women. Clin Infect Dis. 2014 Jul 01; 59(1):127-35.
- Melo VH, Guimaraes MD, Rocha GM, Araujo AC, Carmo RA, Grinsztejn B, Pilotto JH, Palefsky JM. Prevalence and risk factors associated with anal intraepithelial neoplasia among HIV-positive men in Brazil. J Low Genit Tract Dis. 2014 Apr; 18(2):128-35.
- Berry-Lawhorn JM, Chrobak D, Jay N, Palefsky JM. Who is ready to screen for anal squamous intraepithelial lesions and why should they perform high-resolution anoscopy? Sex Transm Dis. 2014 Apr; 41(4):254-6.
- Ortiz AP, Ortiz-Ortiz KJ, Traverso-Ortiz M, Ríos MY, Colón-López V, Palefsky JM. Anal cancer trends in Puerto Rico from 1985 to 2005: the potential impact of the AIDS epidemic. AIDS Patient Care STDS. 2014 Apr; 28(4):165-7.
- King CM, Johnston JS, Ofili K, Tam M, Palefsky J, Da Costa M, Mathur Y, Barbosa P. Human papillomavirus types 2, 27, and 57 Identified in plantar verrucae from HIV-positive and HIV-negative individuals. J Am Podiatr Med Assoc. 2014 Mar; 104(2):141-6.
- Moreira ED, Giuliano AR, Palefsky J, Flores CA, Goldstone S, Ferris D, Hillman RJ, Moi H, Stoler MH, Marshall B, Vuocolo S, Guris D, Haupt RM. Incidence, clearance, and disease progression of genital human papillomavirus infection in heterosexual men. J Infect Dis. 2014 Jul 15; 210(2):192-9.
- Strickler HD, Martinson J, Desai S, Xie X, Burk RD, Anastos K, Massad LS, Minkoff H, Xue X, D'Souza G, Levine AM, Colie C, Watts DH, Palefsky JM, Landay A. The relation of plasmacytoid dendritic cells (pDCs) and regulatory T-cells (Tregs) with HPV persistence in HIV-infected and HIV-uninfected women. Viral Immunol. 2014 Feb; 27(1):20-5.
- Colón-López V, Ortiz AP, Del Toro-Mejías L, Clatts MC, Palefsky JM. Epidemiology of anal HPV infection in high-risk men attending a sexually transmitted infection clinic in Puerto Rico. PLoS One. 2014; 9(1):e83209.
- Palefsky J. HPV vaccination in India. South Asian J Cancer. 2014 Jan; 3(1):93-4.
- Sharma R, Efird JT, Chein A, Holly EA, Krajden M, Berry JM, Darragh TM, Jay N, Palefsky JM. Prevalence and risk factors for neutralizing antibodies to human papillomavirus types 16 and 18 in HIV-positive men who have sex with men. J Acquir Immune Defic Syndr. 2013 Dec 15; 64(5):479-87.