Joel Palefsky, MD

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Joel Palefsky, MD

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Professor, School of Medicine
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Biography

Joel Palefsky, M.D., C.M., F.R.C.P.(C). Professor of Medicine and Infectious Diseases at the University of California San Francisco School of Medicine. He is an internationally recognized expert on the molecular biology, treatment, pathogenesis and natural history of anogenital human papillomavirus infections, particularly in the setting of HIV infection. He is the director of the world's first clinic devoted to prevention of anal cancer, the Anal Neoplasia Clinic Research and Education Center at the UCSF Cancer Center. He is the vice-chair of the National Cancer Institute (NCI)-supported AIDS Malignancy Consortium. He is the chair of the Anal Cancer /HSIL Outcomes Research (ANCHOR) Study, a national multi-site NIH study designed to determine whether treatment of anal cancer precursor lesions prevents the development of anal cancer and to identify biomarkers of progression. He is founder and past president of the International Anal Neoplasia Society and is past president of the International Papillomavirus Society. He is the founder and chairperson of the IPVS International HPV Awareness Campaign.
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  1. Palefsky JM, Holly EA, Ralston ML, Arthur SP, Hogeboom CJ, Darragh TM. Anal cytological abnormalities and anal HPV infection in men with Centers for Disease Control group IV HIV disease. Genitourin Med. 1997 Jun; 73(3):174-80.
  2. Palefsky JM. Cutaneous and genital HPV-associated lesions in HIV-infected patients. Clin Dermatol. 1997 May-Jun; 15(3):439-47.
  3. Maurer TA, Christian KV, Kerschmann RL, Berzin B, Palefsky JM, Payne D, Tyring SK, Berger TG. Cutaneous squamous cell carcinoma in human immunodeficiency virus-infected patients. A study of epidemiologic risk factors, human papillomavirus, and p53 expression. Arch Dermatol. 1997 May; 133(5):577-83.
  4. Palefsky JM, Peñaranda ME, Pierik LT, Lagenaur LA, MacPhail LA, Greenspan D, Greenspan JS. Epstein-Barr virus BMRF-2 and BDLF-3 expression in hairy leukoplakia. Oral Dis. 1997 May; 3 Suppl 1:S171-6.
  5. Palefsky JM, Holly EA, Hogeboom CJ, Berry JM, Jay N, Darragh TM. Anal cytology as a screening tool for anal squamous intraepithelial lesions. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Apr 15; 14(5):415-22.
  6. Nakagawa M, Stites DP, Farhat S, Sisler JR, Moss B, Kong F, Moscicki AB, Palefsky JM. Cytotoxic T lymphocyte responses to E6 and E7 proteins of human papillomavirus type 16: relationship to cervical intraepithelial neoplasia. J Infect Dis. 1997 Apr; 175(4):927-31.
  7. Palefsky JM, Barrasso R. HPV infection and disease in men. Obstet Gynecol Clin North Am. 1996 Dec; 23(4):895-916.
  8. Melbye M, Smith E, Wohlfahrt J, Osterlind A, Orholm M, Bergmann OJ, Mathiesen L, Darragh TM, Palefsky JM. Anal and cervical abnormality in women--prediction by human papillomavirus tests. Int J Cancer. 1996 Nov 27; 68(5):559-64.
  9. Northfelt DW, Swift PS, Palefsky JM. Anal neoplasia. Pathogenesis, diagnosis, and management. Hematol Oncol Clin North Am. 1996 Oct; 10(5):1177-87.
  10. Palefsky JM, Berline J, Penaranda ME, Lennette ET, Greenspan D, Greenspan JS. Sequence variation of latent membrane protein-1 of Epstein-Barr virus strains associated with hairy leukoplakia. J Infect Dis. 1996 Mar; 173(3):710-4.
  11. Nakagawa M, Stites DP, Farhat S, Judd A, Moscicki AB, Canchola AJ, Hilton JF, Palefsky JM. T-cell proliferative response to human papillomavirus type 16 peptides: relationship to cervical intraepithelial neoplasia. Clin Diagn Lab Immunol. 1996 Mar; 3(2):205-10.
  12. Rattray C, Strickler HD, Escoffery C, Cranston B, Brown C, Manns A, Schiffman MH, Palefsky JM, Hanchard B, Blattner WA. Type-specific prevalence of human papillomavirus DNA among Jamaican colposcopy patients. J Infect Dis. 1996 Mar; 173(3):718-21.
  13. Palefsky J. Human papillomavirus-associated malignancies in HIV-positive men and women. Curr Opin Oncol. 1995 Sep; 7(5):437-41.
  14. Turner MA, Palefsky JM. Urokinase plasminogen activator expression by primary and HPV 16-transformed keratinocytes. Clin Exp Metastasis. 1995 Jul; 13(4):260-8.
  15. Palefsky JM, Holly EA. Molecular virology and epidemiology of human papillomavirus and cervical cancer. Cancer Epidemiol Biomarkers Prev. 1995 Jun; 4(4):415-28.
  16. Palefsky JM, Silverman S, Abdel-Salaam M, Daniels TE, Greenspan JS. Association between proliferative verrucous leukoplakia and infection with human papillomavirus type 16. J Oral Pathol Med. 1995 May; 24(5):193-7.
  17. Strickler HD, Rattray C, Escoffery C, Manns A, Schiffman MH, Brown C, Cranston B, Hanchard B, Palefsky JM, Blattner WA. Human T-cell lymphotropic virus type I and severe neoplasia of the cervix in Jamaica. Int J Cancer. 1995 Mar 29; 61(1):23-6.
  18. Palefsky JM. Serologic detection of human papillomavirus-related anogenital disease: new opportunities and challenges. J Natl Cancer Inst. 1995 Mar 15; 87(6):401-2.
  19. Palefsky JM, Shiboski S, Moss A. Risk factors for anal human papillomavirus infection and anal cytologic abnormalities in HIV-positive and HIV-negative homosexual men. J Acquir Immune Defic Syndr. 1994 Jun; 7(6):599-606.
  20. Palefsky JM. Anal human papillomavirus infection and anal cancer in HIV-positive individuals: an emerging problem. AIDS. 1994 Mar; 8(3):283-95.
  21. Siadat-Pajouh M, Periasamy A, Ayscue AH, Moscicki AB, Palefsky JM, Walton L, DeMars LR, Power JD, Herman B, Lockett SJ. Detection of human papillomavirus type 16/18 DNA in cervicovaginal cells by fluorescence based in situ hybridization and automated image cytometry. Cytometry. 1994 Mar 01; 15(3):245-57.
  22. Williams AB, Darragh TM, Vranizan K, Ochia C, Moss AR, Palefsky JM. Anal and cervical human papillomavirus infection and risk of anal and cervical epithelial abnormalities in human immunodeficiency virus-infected women. Obstet Gynecol. 1994 Feb; 83(2):205-11.
  23. Moscicki AB, Palefsky J, Smith G, Siboshski S, Schoolnik G. Variability of human papillomavirus DNA testing in a longitudinal cohort of young women. Obstet Gynecol. 1993 Oct; 82(4 Pt 1):578-85.
  24. Moscicki AB, Broering J, Powell K, Klein J, Clayton L, Smith G, Boero S, Darragh TM, Brescia RJ, Palefsky J. Comparison between colposcopic, cytologic, and histologic findings in women positive and negative for human papillomavirus DNA. J Adolesc Health. 1993 Mar; 14(2):74-9.
  25. Lammel CJ, Dekker NP, Palefsky J, Brooks GF. In vitro model of Haemophilus ducreyi adherence to and entry into eukaryotic cells of genital origin. J Infect Dis. 1993 Mar; 167(3):642-50.