Joel Palefsky, MD

Headshot of Joel Palefsky
User Profile Photo

Joel Palefsky, MD

User Profile Name
Member, CFAR Scientific Council
Professor, School of Medicine
User Profile Title
User Profile Email

Biography

Joel Palefsky, M.D., C.M., F.R.C.P.(C). Professor of Medicine and Infectious Diseases at the University of California San Francisco School of Medicine. He is an internationally recognized expert on the molecular biology, treatment, pathogenesis and natural history of anogenital human papillomavirus infections, particularly in the setting of HIV infection. He is the director of the world's first clinic devoted to prevention of anal cancer, the Anal Neoplasia Clinic Research and Education Center at the UCSF Cancer Center. He is the vice-chair of the National Cancer Institute (NCI)-supported AIDS Malignancy Consortium. He is the chair of the Anal Cancer /HSIL Outcomes Research (ANCHOR) Study, a national multi-site NIH study designed to determine whether treatment of anal cancer precursor lesions prevents the development of anal cancer and to identify biomarkers of progression. He is founder and past president of the International Anal Neoplasia Society and is past president of the International Papillomavirus Society. He is the founder and chairperson of the IPVS International HPV Awareness Campaign.
CTSI Profile Bio

Displaying 301 - 325 of 366

  1. Goldie SJ, Kuntz KM, Weinstein MC, Freedberg KA, Palefsky JM. Cost-effectiveness of screening for anal squamous intraepithelial lesions and anal cancer in human immunodeficiency virus-negative homosexual and bisexual men. Am J Med. 2000 Jun 01; 108(8):634-41.
  2. Litle VR, Leavenworth JD, Darragh TM, Kosinski LA, Moore DH, Smith-McCune KK, Warren RS, Palefsky JM, Welton ML. Angiogenesis, proliferation, and apoptosis in anal high-grade squamous intraepithelial lesions. Dis Colon Rectum. 2000 Mar; 43(3):346-52.
  3. de Jong A, Palefsky JM, Stites DP, Nakagawa M. Human immunodeficiency virus-positive individuals with oral hairy leukoplakia are able to mount cytotoxic T lymphocyte responses to Epstein-Barr virus. Oral Dis. 2000 Jan; 6(1):40-7.
  4. Palefsky JM. Human papillomavirus-related tumors. AIDS. 2000; 14 Suppl 3:S189-95.
  5. Strickler HD, Goedert JJ, Bethke FR, Trubey CM, O'Brien TR, Palefsky J, Whitman JE, Ablashi D, Zeichner S, Shearer GM. Human herpesvirus 8 cellular immune responses in homosexual men. J Infect Dis. 1999 Nov; 180(5):1682-5.
  6. Strickler HD, Viscidi R, Escoffery C, Rattray C, Kotloff KL, Goldberg J, Manns A, Rabkin C, Daniel R, Hanchard B, Brown C, Hutchinson M, Zanizer D, Palefsky J, Burk RD, Cranston B, Clayman B, Shah KV. Adeno-associated virus and development of cervical neoplasia. J Med Virol. 1999 Sep; 59(1):60-5.
  7. Palefsky JM. Anal squamous intraepithelial lesions: relation to HIV and human papillomavirus infection. J Acquir Immune Defic Syndr. 1999 Aug 01; 21 Suppl 1:S42-8.
  8. Lagenaur LA, Palefsky JM. Regulation of Epstein-Barr virus promoters in oral epithelial cells and lymphocytes. J Virol. 1999 Aug; 73(8):6566-72.
  9. Nakagawa M, Stites DP, Palefsky JM, Kneass Z, Moscicki AB. CD4-positive and CD8-positive cytotoxic T lymphocytes contribute to human papillomavirus type 16 E6 and E7 responses. Clin Diagn Lab Immunol. 1999 Jul; 6(4):494-8.
  10. Goldie SJ, Kuntz KM, Weinstein MC, Freedberg KA, Welton ML, Palefsky JM. The clinical effectiveness and cost-effectiveness of screening for anal squamous intraepithelial lesions in homosexual and bisexual HIV-positive men. JAMA. 1999 May 19; 281(19):1822-9.
  11. Massad LS, Riester KA, Anastos KM, Fruchter RG, Palefsky JM, Burk RD, Burns D, Greenblatt RM, Muderspach LI, Miotti P. Prevalence and predictors of squamous cell abnormalities in Papanicolaou smears from women infected with HIV-1. Women's Interagency HIV Study Group. . 1999 May 01; 21(1):33-41.
  12. Palefsky JM, Minkoff H, Kalish LA, Levine A, Sacks HS, Garcia P, Young M, Melnick S, Miotti P, Burk R. Cervicovaginal human papillomavirus infection in human immunodeficiency virus-1 (HIV)-positive and high-risk HIV-negative women. J Natl Cancer Inst. 1999 Feb 03; 91(3):226-36.
  13. Moscicki AB, Hills NK, Shiboski S, Darragh TM, Jay N, Powell K, Hanson E, Miller SB, Farhat S, Palefsky J. Risk factors for abnormal anal cytology in young heterosexual women. Cancer Epidemiol Biomarkers Prev. 1999 Feb; 8(2):173-8.
  14. Darragh T, Jay N, Berry M, Costa MD, Ralston M, Holly E, Palefsky J. Papillary lesions of the anal canal. J Low Genit Tract Dis. 1999 Jan; 3(1):36.
  15. Palefsky JM, Holly EA, Ralston ML, Arthur SP, Jay N, Berry JM, DaCosta MM, Botts R, Darragh TM. Anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual and bisexual men: prevalence and risk factors. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Apr 01; 17(4):320-6.
  16. Palefsky JM, Holly EA, Hogeboom CJ, Ralston ML, DaCosta MM, Botts R, Berry JM, Jay N, Darragh TM. Virologic, immunologic, and clinical parameters in the incidence and progression of anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual men. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Apr 01; 17(4):314-9.
  17. Palefsky JM, Holly EA, Ralston ML, Jay N, Berry JM, Darragh TM. High incidence of anal high-grade squamous intra-epithelial lesions among HIV-positive and HIV-negative homosexual and bisexual men. AIDS. 1998 Mar 26; 12(5):495-503.
  18. Palefsky JM, Holly EA, Ralston ML, Jay N. Prevalence and risk factors for human papillomavirus infection of the anal canal in human immunodeficiency virus (HIV)-positive and HIV-negative homosexual men. J Infect Dis. 1998 Feb; 177(2):361-7.
  19. Moscicki AB, Shiboski S, Broering J, Powell K, Clayton L, Jay N, Darragh TM, Brescia R, Kanowitz S, Miller SB, Stone J, Hanson E, Palefsky J. The natural history of human papillomavirus infection as measured by repeated DNA testing in adolescent and young women. J Pediatr. 1998 Feb; 132(2):277-84.
  20. Palefsky JM. Human papillomavirus infection and anogenital neoplasia in human immunodeficiency virus-positive men and women. J Natl Cancer Inst Monogr. 1998; (23):15-20.
  21. Peñaranda ME, Lagenaur LA, Pierik LT, Berline JW, MacPhail LA, Greenspan D, Greenspan JS, Palefsky JM. Expression of Epstein-Barr virus BMRF-2 and BDLF-3 genes in hairy leukoplakia. J Gen Virol. 1997 Dec; 78 ( Pt 12):3361-70.
  22. Koch A, Hansen SV, Nielsen NM, Palefsky J, Melbye M. HPV detection in children prior to sexual debut. Int J Cancer. 1997 Nov 27; 73(5):621-4.
  23. Turner MA, Darragh T, Palefsky JM. Epithelial-stromal interactions modulating penetration of matrigel membranes by HPV 16-immortalized keratinocytes. J Invest Dermatol. 1997 Nov; 109(5):619-25.
  24. Jay N, Berry JM, Hogeboom CJ, Holly EA, Darragh TM, Palefsky JM. Colposcopic appearance of anal squamous intraepithelial lesions: relationship to histopathology. Dis Colon Rectum. 1997 Aug; 40(8):919-28.
  25. Darragh TM, Jay N, Tupkelewicz BA, Hogeboom CJ, Holly EA, Palefsky JM. Comparison of conventional cytologic smears and ThinPrep preparations from the anal canal. Acta Cytol. 1997 Jul-Aug; 41(4):1167-70.