Dr. Ciccarone's research is centered on the contextual issues of treatment and prevention of HIV/AIDS, and related diseases, in socially marginalized populations. His long-term objective is to combine ethnographic and epidemiological research to explore the intricate socio-behavioral-medical issues of medication adherence, access to care and risk taking behaviors, particularly related to drug use and drug users. His work, including collaborations, has been published in JAMA, NEJM, PLoS Medicine, AJPH, JAIDS and other peer-reviewed journals.
His recent research is in exploring the different medical consequences of use of various sources and forms of heroin. The US has recently entered a new heroin epidemic, this time fueled by the recent opioid pill epidemic. His team is exploring the economic, anthropological, historical, clinical and public health dimensions of this crisis.