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Adithya Cattamanchi, MD, MAS
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Professor, School of Medicine
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Biography
My research is focused on two thematic areas: 1) Development and evaluation of tuberculosis (TB) diagnostics and 2) Implementation and dissemination of evidence-based preventative, diagnostic, and treatment interventions for TB. I have considerable experience with the evaluation of TB diagnostics in low-income countries, including studying the impact of new diagnostics on patient- and public health-important outcomes. I have served on several World Health Organization (WHO) Expert Group panels to develop new policies related to TB diagnostics and serve as a faculty member for the Advanced Tuberculosis Diagnostics Research workshop sponsored by the WHO Stop TB Partnership. I have initiated a number of collaborations with engineers in industry and academia to develop and evaluate new diagnostic platforms for TB including: 1) mobile phone-based microscopy; 2) mobile phone-based molecular diagnostic platforms; and 3) single-particle aerosol mass spectrometry. We are currently evaluating the mobile phone-based microscopy platform and health centers in Hanoi, Vietnam in a demonstration project funded by the TB REACH initiative.
In addition to research on TB diagnostics, I have developed an active research agenda related to implementation science. I helped establish a platform for monitoring the quality of TB care at 6 rural health centers in Uganda (Uganda Tuberculosis Surveillance Project). My current work, supported through an NIH/NIAID R21 in Implementation and Dissemination Science, is focused on improving the quality of TB suspect evaluation at these health centers.
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Displaying 26 - 50 of 202
- Richardson S, Dauber-Decker KL, McGinn T, Barnaby DP, Cattamanchi A, Pekmezaris R. Barriers to the Use of Clinical Decision Support for the Evaluation of Pulmonary Embolism: Qualitative Interview Study. JMIR Hum Factors. 2021 Aug 04; 8(3):e25046.
- Huddart S, Savic RM, Cattamanchi A. Is Glycemic Control the Secret to Tuberculosis Control? Am J Respir Crit Care Med. 2021 08 01; 204(3):254-255.
- Fossati A, Richards AL, Chen KH, Jaganath D, Cattamanchi A, Ernst JD, Swaney DL. Toward Comprehensive Plasma Proteomics by Orthogonal Protease Digestion. J Proteome Res. 2021 08 06; 20(8):4031-4040.
- Connelly JT, Andama A, Grant BD, Ball A, Mwebe S, Asege L, Nakaye M, Lopez BB, Hsieh HV, Katumba D, Mukwatamundu J, Nalubega M, Hunt VM, Burkot S, Ramachandraiah H, Choudhary A, Ignatowicz L, Weigl BH, Bachman C, Mulondo J, Semitala F, Worodria W, Pinter A, Hamasur B, Bell D, Cattamanchi A, Somoskovi A. Field evaluation of a prototype tuberculosis lipoarabinomannan lateral flow assay on HIV-positive and HIV-negative patients. PLoS One. 2021; 16(7):e0254156.
- Samuels THA, Shete PB, Ojok C, Nalugwa T, Farr K, Turyahabwe S, Katamba A, Cattamanchi A, Moore DAJ. Where will it end? Pathways to care and catastrophic costs following negative TB evaluation in Uganda. PLoS One. 2021; 16(7):e0253927.
- Semitala FC, Musinguzi A, Ssemata J, Welishe F, Nabunje J, Kadota JL, Berger CA, Katamba A, Kiwanuka N, Kamya MR, Dowdy D, Cattamanchi A, Katahoire AR. Acceptance and completion of rifapentine-based TB preventive therapy (3HP) among people living with HIV (PLHIV) in Kampala, Uganda-patient and health worker perspectives. Implement Sci Commun. 2021 Jun 30; 2(1):71.
- Kendall EA, Kitonsa PJ, Nalutaaya A, Erisa KC, Mukiibi J, Nakasolya O, Isooba D, Baik Y, Robsky KO, Kato-Maeda M, Cattamanchi A, Katamba A, Dowdy DW. The Spectrum of Tuberculosis Disease in an Urban Ugandan Community and Its Health Facilities. Clin Infect Dis. 2021 06 15; 72(12):e1035-e1043.
- Jaganath D, Wambi P, Reza TF, Nakafeero J, Aben EO, Kiconco E, Nannyonga G, Nsereko M, Sekadde MP, Mudiope M, Kato-Maeda M, Starke J, Andama A, Mohanty S, Wobudeya E, Cattamanchi A. A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda. J Pediatric Infect Dis Soc. 2021 May 28; 10(5):586-592.
- Wood RC, Andama A, Hermansky G, Burkot S, Asege L, Job M, Katumba D, Nakaye M, Mwebe SZ, Mulondo J, Bachman CM, Nichols KP, Le Ny AM, Ortega C, Olson RN, Weigel KM, Olson AM, Madan D, Bell D, Cattamanchi A, Worodria W, Semitala FC, Somoskovi A, Cangelosi GA, Minch KJ. Characterization of oral swab samples for diagnosis of pulmonary tuberculosis. PLoS One. 2021; 16(5):e0251422.
- Cattamanchi A, Crowder R, Kityamuwesi A, Kiwanuka N, Lamunu M, Namale C, Tinka LK, Nakate AS, Ggita J, Turimumahoro P, Babirye D, Oyuku D, Berger C, Tucker A, Patel D, Sammann A, Turyahabwe S, Dowdy D, Katamba A. Digital adherence technology for tuberculosis treatment supervision: A stepped-wedge cluster-randomized trial in Uganda. PLoS Med. 2021 05; 18(5):e1003628.
- Kalema N, Semeere A, Banturaki G, Kyamugabwa A, Ssozi S, Ggita J, Kabajaasi O, Kambugu A, Kigozi J, Muganzi A, Castelnuovo B, Cattamanchi A, Armstrong-Hough M. Gaps in TB preventive therapy for persons initiating antiretroviral therapy in Uganda: an explanatory sequential cascade analysis. Int J Tuberc Lung Dis. 2021 05 01; 25(5):388-394.
- Feng PJ, Wu Y, Ho CS, Chinna L, Whelen AC, Largen A, Brostrom R, Reves R, Belknap R, Cattamanchi A, Banaei N. Impact of T-Cell Xtend on T-SPOT.TB Assay in High-Risk Individuals after Delayed Blood Sample Processing. J Clin Microbiol. 2021 04 20; 59(5).
- Kadota JL, Nabwire S, Nalugwa T, White JS, Cattamanchi A, Katamba A, Shete PB. Patient Perspectives and Willingness to Accept Incentives for Tuberculosis Diagnostic Evaluation in Uganda. Value Health Reg Issues. 2021 Sep; 25:48-56.
- Hassan S, Sobers N, Paul-Charles J, Herbert J, Dharamraj K, Cruz E, Garcia E, Fredericks L, Desai MM, Roy S, Williams S, Linnander E, Crusto C, Horowitz CR, Arniella G, Cattamanchi A, Adams OP, Nunez-Smith M. Diabetes prevention in the Caribbean using Lifestyle Intervention and Metformin Escalation (LIME): Protocol for a hybrid Type-1 effectiveness-implementation trial using a quasi-experimental study design. Contemp Clin Trials Commun. 2021 Jun; 22:100750.
- Reza TF, Nalugwa T, Nantale M, Adams K, Fielding K, Nakaweesa A, Oyuku D, Nabwire S, Musinguzi J, Ojok C, Babirye D, Ackerman SL, Handley MA, Kityamuwesi A, Dowdy DW, Moore DAJ, Davis JL, Turyahabwe S, Katamba A, Cattamanchi A. Design and execution of a public randomization ceremony to enhance stakeholder engagement within a cluster randomized trial to improve tuberculosis diagnosis in Uganda. Contemp Clin Trials Commun. 2021 Jun; 22:100707.
- Lim RK, Semitala FC, Atuhumuza E, Sabiti L, Namakula-Katende J, Muyindike WR, Kamya MR, Dowdy D, Cattamanchi A. Patient choice improves self-efficacy and intention to complete tuberculosis preventive therapy in a routine HIV program setting in Uganda. PLoS One. 2021; 16(2):e0246113.
- Andama A, Jaganath D, Crowder R, Asege L, Nakaye M, Katumba D, Mukwatamundu J, Mwebe S, Semitala CF, Worodria W, Joloba M, Mohanty S, Somoskovi A, Cattamanchi A. The transition to Xpert MTB/RIF ultra: diagnostic accuracy for pulmonary tuberculosis in Kampala, Uganda. BMC Infect Dis. 2021 Jan 11; 21(1):49.
- Tucker A, Oyuku D, Nalugwa T, Nantale M, Ferguson O, Farr K, Reza TF, Shete PB, Cattamanchi A, Dowdy DW, Sohn H, Katamba A. Costs along the TB diagnostic pathway in Uganda. Int J Tuberc Lung Dis. 2021 01 01; 25(1):61-63.
- Vivek Jain, Lillian B Brown, Carina Marquez, Luis Rubio, Natasha Spottiswoode, Bethlehem Churnet, Katherine Brooks, Mengyu Zhou, Timothy Muldoon, Carolyn Hendrickson, Adithya Cattamanchi, Antonio Gomez, Brian Haas, Edwin Charlebois, Annie Luetkemeyer, Annie Luetkemeyer, Monica Gandhi, Diane Havlir, Sumant Ranji, Lisa Gail Winston. 448. Disproportionate Burden of COVID-19 on Latinx Residents among Hospitalized Patients at San Francisco’s Public Health Hospital. Open Forum Infectious Diseases. 2020 Dec 31; 7(Suppl 1):s292-s292.
- Meyer AJ, Ochom E, Turimumahoro P, Byanyima P, Sanyu I, Lalitha R, Kaswabuli S, Andama A, Walter ND, Katamba A, Cattamanchi A, Worodria W, Huang L, Yoon C, Davis JL. C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study. J Clin Microbiol. 2020 12 17; 59(1).
- Meyer AJ, Ochom E, Turimumahoro P, Byanyima P, Sanyu I, Lalitha R, Kaswabuli S, Andama A, Walter ND, Katamba A, Cattamanchi A, Worodria W, Huang L, Yoon C, Davis JL. C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study. J Clin Microbiol. 2020 12 17; 59(1).
- Patel D, Berger CA, Kityamuwesi A, Ggita J, Kunihira Tinka L, Turimumahoro P, Feler J, Chehab L, Chen AZ, Gupta N, Turyahabwe S, Katamba A, Cattamanchi A, Sammann A. Iterative Adaptation of a Tuberculosis Digital Medication Adherence Technology to Meet User Needs: Qualitative Study of Patients and Health Care Providers Using Human-Centered Design Methods. JMIR Form Res. 2020 Dec 08; 4(12):e19270.
- Zawedde-Muyanja S, Katamba A, Cattamanchi A, Castelnuovo B, Manabe YC. Patient and health system factors associated with pretreatment loss to follow up among patients diagnosed with tuberculosis using Xpert® MTB/RIF testing in Uganda. BMC Public Health. 2020 Dec 03; 20(1):1855.
- Kaiser S, Gupta N, Mendoza J, Azzarone G, Parikh K, Nazif J, Cattamanchi A. Predictors of Quality Improvement in Pediatric Asthma Care. Hosp Pediatr. 2020 12; 10(12):1114-1119.
- Crowder R, Kityamuwesi A, Kiwanuka N, Lamunu M, Namale C, Tinka LK, Nakate AS, Ggita J, Turimumahoro P, Babirye D, Oyuku D, Berger CA, Tucker A, Patel D, Sammann A, Dowdy D, Stavia T, Cattamanchi A, Katamba A. Study protocol and implementation details for a pragmatic, stepped-wedge cluster randomised trial of a digital adherence technology to facilitate tuberculosis treatment completion. BMJ Open. 2020 11 27; 10(11):e039895.