Victor Valcour, MD

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(415) 476-3746

675 Nelson Rising Lane
San Francisco, CA 94158

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  • Professor, School of Medicine
  • Member, CFAR Scientific Council

Biography

OVERVIEW

Dr. Valcour is a Professor of Medicine with a shared appointment in the Division of Geriatric Medicine and the Department of Neurology. His work crosses disciplines to research and care for cognitive disorders in aging populations and to understand brain injury in the setting of HIV among all ages, including funded pediatric HIV studies. His clinical work involves consultations for patients with cognitive disorders at the Memory and Aging Center/UCSF.

While much of Dr. Valcour's research is completed at UCSF, he has a large internationa porfolio with many opportunities for junior investigators. Within Southeast Asia, he is Deputy Director of SEARCH/Thailand operating research in acute HIV (within days of infection), pediatric HIV, and markers of dementia in chronic HIV. In Africa, he has partnered with the US Military HIV Research Program to survey cognitive disorders among HIV-infected individuals in Nigeria, Uganda, Kenya, and Tanzania.

Dr. Valcour is broadly involved in mentoring individuals at all levels of training who are interested in clinical research related to cognitive disorders, particularly in association with HIV infection. He has extensive global health experience.

RESEARCH

Dr. Valcour’s research interests have two major emphases. He is currently developing a research program that aims to understand optimal care strategies for elders who develop dementia. Nested within the UCSF Memory and Aging Center, the long-term goal of this program is to provide model care for elders with cognitive disorders.

Dr. Valcour is internationally recognized for research in cognitive disorders related to HIV. He currently operates 3 NIH R01 series grants within 3 novel cohorts: (1) a chronic HIV infected cohort followed since first initiation of cART; (2) an acute HIV cohort of individuals infected for less than one month at enrollment; (3) and a pediatric cohort in Thailand and Cambodia. He is the Deputy Director of SEARCH/Thailand (www.SEARCHThailand.org). He also operates the UCSF HIV Over 60 Cohort focused on understanding cognitive disorders in the older HIV population living in the San Francisco Bay area. New research will survey of cognitive disorders in HIV for individuals living in Uganda, Kenya, Tanzania and Nigeria.

ACADEMIC FOCUS

Dr. Valcour is actively engaged in mentoring individuals wishing to become independent clinical researchers. His research portfolio provides a broad array of local and international projects that can serve as resources for mentored projects. Dr. Valcour serves as an Executive Committee member of the AIDS Research Institute (ARI)

Awards

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  1. Hellmuth J, Muccini C, Colby DJ, Kroon E, de Souza M, Crowell TA, Chan P, Sacdalan C, Intasan J, Benjapornpong K, Tipsuk S, Puttamaswin S, Chomchey N, Valcour V, Sarnecki M, Tomaka F, Krebs SJ, Slike BM, Jagodzinski LL, Dumrongpisutikul N, Sailasuta N, Samboju V, Michael NL, Robb ML, Vasan S, Ananworanich J, Phanuphak P, Phanuphak N, Paul R, Spudich S. Central Nervous System Safety During Brief Analytic Treatment Interruption of Antiretroviral Therapy Within 4 Human Immunodeficiency Virus Remission Trials: An Observational Study in Acutely Treated People Living With Human Immunodeficiency Virus. Clin Infect Dis. 2021 Oct 05; 73(7):e1885-e1892. View on Pubmed
  2. Corley MJ, Sacdalan C, Pang APS, Chomchey N, Ratnaratorn N, Valcour V, Kroon E, Cho KS, Belden AC, Colby D, Robb M, Hsu D, Spudich S, Paul R, Vasan S, Ndhlovu LC, SEARCH010/RV254 and SEARCH013/RV304 study groups . Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART. PLoS Pathog. 2021 Aug; 17(8):e1009785. View on Pubmed
  3. Samboju V, Cobigo Y, Paul R, Naasan G, Hillis M, Tsuei T, Javandel S, Valcour V, Milanini B. Cerebrovascular Disease Correlates With Longitudinal Brain Atrophy in Virally Suppressed Older People Living With HIV. J Acquir Immune Defic Syndr. 2021 Aug 01; 87(4):1079-1085. View on Pubmed
  4. Paul R, Tsuei T, Cho K, Belden A, Milanini B, Bolzenius J, Javandel S, McBride J, Cysique L, Lesinski S, Valcour V. Ensemble machine learning classification of daily living abilities among older people with HIV. EClinicalMedicine. 2021 May; 35:100845. View on Pubmed
  5. Chan P, Kerr SJ, Kroon E, Colby D, Sacdalan C, Hellmuth J, Reiss P, Vasan S, Ananworanich J, Valcour V, Spudich S, Paul R, RV254/SEARCH 010 Research Team . Cognitive trajectories after treatment in acute HIV infection. AIDS. 2021 05 01; 35(6):883-888. View on Pubmed
  6. Chan P, Colby DJ, Kroon E, Sacdalan C, Pinyakorn S, Paul R, Robb M, Valcour V, Ananworanich J, Marra C, Spudich S. Clinical and laboratory impact of concomitant syphilis infection during acute HIV. HIV Med. 2021 Jul; 22(6):502-511. View on Pubmed
  7. Ibanez A, Yokoyama JS, Possin KL, Matallana D, Lopera F, Nitrini R, Takada LT, Custodio N, Sosa Ortiz AL, Avila-Funes JA, Behrens MI, Slachevsky A, Myers RM, Cochran JN, Brusco LI, Bruno MA, Brucki SMD, Pina-Escudero SD, Okada de Oliveira M, Donnelly Kehoe P, Garcia AM, Cardona JF, Santamaria-Garcia H, Moguilner S, Duran-Aniotz C, Tagliazucchi E, Maito M, Longoria Ibarrola EM, Pintado-Caipa M, Godoy ME, Bakman V, Javandel S, Kosik KS, Valcour V, Miller BL. The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science. Front Neurol. 2021; 12:631722. View on Pubmed
  8. Llibre-Guerra JJ, Li Y, Allen IE, Llibre-Guerra JC, Rodríguez Salgado AM, Peñalver AI, Sanchez AA, Yokoyama JS, Grinberg L, Valcour V, Miller BL, Llibre-Rodríguez JJ. Race, genetic admixture and cognitive performance in the Cuban population. J Gerontol A Biol Sci Med Sci. 2021 Feb 27. View on Pubmed
  9. Nir TM, Fouche JP, Ananworanich J, Ances BM, Boban J, Brew BJ, Chaganti JR, Chang L, Ching CRK, Cysique LA, Ernst T, Faskowitz J, Gupta V, Harezlak J, Heaps-Woodruff JM, Hinkin CH, Hoare J, Joska JA, Kallianpur KJ, Kuhn T, Lam HY, Law M, Lebrun-Frénay C, Levine AJ, Mondot L, Nakamoto BK, Navia BA, Pennec X, Porges EC, Salminen LE, Shikuma CM, Surento W, Thames AD, Valcour V, Vassallo M, Woods AJ, Thompson PM, Cohen RA, Paul R, Stein DJ, Jahanshad N. Association of Immunosuppression and Viral Load With Subcortical Brain Volume in an International Sample of People Living With HIV. JAMA Netw Open. 2021 01 04; 4(1):e2031190. View on Pubmed
  10. Rodríguez-Salgado AM, Llibre-Guerra JJ, Tsoy E, Peñalver-Guia AI, Bringas G, Erlhoff SJ, Kramer JH, Allen IE, Valcour V, Miller BL, Llibre-Rodríguez JJ, Possin KL. A Brief Digital Cognitive Assessment for Detection of Cognitive Impairment in Cuban Older Adults. J Alzheimers Dis. 2021; 79(1):85-94. View on Pubmed
  11. Tsoy E, Sideman AB, Piña Escudero SD, Pintado-Caipa M, Kanjanapong S, Al-Rousan T, Mbakile-Mahlanza L, de Oliveira MO, De la Cruz Puebla M, Zygouris S, Mohamed AA, Ibrahim H, Goode CA, Miller BL, Valcour V, Possin KL. Global Perspectives on Brief Cognitive Assessments for Dementia Diagnosis. J Alzheimers Dis. 2021; 82(3):1001-1013. View on Pubmed
  12. Bahemana E, Esber A, Dear N, Ganesan K, Parikh A, Reed D, Maganga L, Khamadi S, Mizinduko M, Lwilla A, Mkondoo D, Mwaisanga G, Somi N, Owouth J, Maswai J, Kiweewa F, Iroezindu M, Ake JA, Crowell TA, Valcour VG, Polyak CS, AFRICOS Study Group . Impact of age on CD4 recovery and viral suppression over time among adults living with HIV who initiated antiretroviral therapy in the African Cohort Study. AIDS Res Ther. 2020 11 12; 17(1):66. View on Pubmed
  13. Fitzgerald KC, Maki PM, Xu Y, Jin W, Dastgheyb R, Williams DW, Springer G, Anastos K, Gustafson D, Spence AB, Adimora AA, Waldrop D, Vance DE, Bolivar H, Valcour VG, Rubin LH. Factors Predicting Detrimental Change in Declarative Memory Among Women With HIV: A Study of Heterogeneity in Cognition. Front Psychol. 2020; 11:548521. View on Pubmed
  14. Addington EL, Javandel S, De Gruttola V, Paul R, Milanini B, Ances BM, Moskowitz JT, Valcour V. Mindfulness-based stress reduction for HIV-associated neurocognitive disorder: Rationale and protocol for a randomized controlled trial in older adults. Contemp Clin Trials. 2020 11; 98:106150. View on Pubmed
  15. Handoko R, Colby DJ, Kroon E, Sacdalan C, de Souza M, Pinyakorn S, Prueksakaew P, Munkong C, Ubolyam S, Akapirat S, Chiarella J, Krebs S, Sereti I, Valcour V, Paul R, Michael NL, Phanuphak N, Ananworanich J, Spudich S, SEARCH 010/RV254 Study Team . Determinants of suboptimal CD4+ T cell recovery after antiretroviral therapy initiation in a prospective cohort of acute HIV-1 infection. J Int AIDS Soc. 2020 09; 23(9):e25585. View on Pubmed
  16. Bobrow K, Xia F, Hoang T, Valcour V, Yaffe K. HIV and risk of dementia in older veterans. AIDS. 2020 09 01; 34(11):1673-1679. View on Pubmed
  17. Sharma V, Bryant C, Montero M, Creegan M, Slike B, Krebs SJ, Ratto-Kim S, Valcour V, Sithinamsuwan P, Chalermchai T, Eller MA, Bolton DL, SEARCH007/SEARCH011 Study Groups . Monocyte and CD4+ T-cell antiviral and innate responses associated with HIV-1 inflammation and cognitive impairment. AIDS. 2020 07 15; 34(9):1289-1301. View on Pubmed
  18. Premeaux TA, Javandel S, Hosaka KRJ, Greene M, Therrien N, Allen IE, Corley MJ, Valcour VG, Ndhlovu LC. Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. Front Immunol. 2020; 11:1321. View on Pubmed
  19. Kamkwalala AR, Wang X, Maki PM, Williams DW, Valcour VG, Damron A, Tien PC, Weber KM, Cohen MH, Sundermann EE, Meyer VJ, Little DM, Xu Y, Rubin LH. Brief Report: Higher Peripheral Monocyte Activation Markers Are Associated With Smaller Frontal and Temporal Cortical Volumes in Women With HIV. J Acquir Immune Defic Syndr. 2020 05 01; 84(1):54-59. View on Pubmed
  20. RifeMagalis B, Strickland SL, Shank SD, Autissier P, Schuetz A, Sithinamsuwan P, Lerdlum S, Fletcher JLK, de Souza M, Ananworanich J, Valcour V, Search007 Study Group , Williams KC, Kosakovsky Pond SL, RattoKim S, Salemi M. Phyloanatomic characterization of the distinct T cell and monocyte contributions to the peripheral blood HIV population within the host. Virus Evol. 2020 Jan; 6(1):veaa005. View on Pubmed
  21. Rubin LH, Xu Y, Norris PJ, Wang X, Dastgheyb R, Fitzgerald KC, Keating SM, Kaplan RC, Maki PM, Anastos K, Springer G, Benning L, Kassaye S, Gustafson DR, Valcour VG, Williams DW. Early Inflammatory Signatures Predict Subsequent Cognition in Long-Term Virally Suppressed Women With HIV. Front Integr Neurosci. 2020; 14:20. View on Pubmed
  22. Sharma V, Bryant C, Montero M, Creegan M, Slike B, Krebs SJ, Ratto-Kim S, Valcour V, Sithinamsuwan P, Chalermchai T, Eller MA, Bolton DL, SEARCH007/SEARCH011 Study Groups . Monocyte and CD4+ T cell antiviral and innate responses associated with HIV-1 inflammation and cognitive impairment. AIDS. 2020 Apr 13. View on Pubmed
  23. Paul RH, Cho KS, Belden AC, Mellins CA, Malee KM, Robbins RN, Salminen LE, Kerr SJ, Adhikari B, Garcia-Egan PM, Sophonphan J, Aurpibul L, Thongpibul K, Kosalaraksa P, Kanjanavanit S, Ngampiyaskul C, Wongsawat J, Vonthanak S, Suwanlerk T, Valcour VG, Preston-Campbell RN, Bolzenious JD, Robb ML, Ananworanich J, Puthanakit T, PREDICT Study Group . Machine-learning classification of neurocognitive performance in children with perinatal HIV initiating de novo antiretroviral therapy. AIDS. 2020 04 01; 34(5):737-748. View on Pubmed
  24. Leyre L, Kroon E, Vandergeeten C, Sacdalan C, Colby DJ, Buranapraditkun S, Schuetz A, Chomchey N, de Souza M, Bakeman W, Fromentin R, Pinyakorn S, Akapirat S, Trichavaroj R, Chottanapund S, Manasnayakorn S, Rerknimitr R, Wattanaboonyoungcharoen P, Kim JH, Tovanabutra S, Schacker TW, O'Connell R, Valcour VG, Phanuphak P, Robb ML, Michael N, Trautmann L, Phanuphak N, Ananworanich J, Chomont N, RV254/SEARCH010, RV304/SEARCH013, SEARCH011 study groups . Abundant HIV-infected cells in blood and tissues are rapidly cleared upon ART initiation during acute HIV infection. Sci Transl Med. 2020 03 04; 12(533). View on Pubmed
  25. Kallianpur KJ, Jahanshad N, Sailasuta N, Benjapornpong K, Chan P, Pothisri M, Dumrongpisutikul N, Laws E, Ndhlovu LC, Clifford KM, Paul R, Jagodzinski L, Krebs S, Ananworanich J, Spudich S, Valcour V, SEARCH010/RV254 Study Group . Regional brain volumetric changes despite 2 years of treatment initiated during acute HIV infection. AIDS. 2020 03 01; 34(3):415-426. View on Pubmed
  26. Milanini B, Allen I, Paul R, Bahemana E, Kiweewa F, Nambuya A, Maswai J, Langat R, Owuoth J, Martin S, Possin K, Esber A, Polyak C, Ake JA, Valcour V, AFRICOS study Team . Frequency and Predictors of HIV-Related Cognitive Impairment in East Africa: The Africa Cohort Study (AFRICOS). J Acquir Immune Defic Syndr. 2020 02 01; 83(2):157-164. View on Pubmed
  27. Chang K, Premeaux TA, Cobigo Y, Milanini B, Hellmuth J, Rubin LH, Javandel S, Allen I, Ndhlovu LC, Paul R, Valcour V. Plasma inflammatory biomarkers link to diffusion tensor imaging metrics in virally suppressed HIV-infected individuals. AIDS. 2020 02 01; 34(2):203-213. View on Pubmed
  28. Philippi CL, Reyna L, Nedderman L, Chan P, Samboju V, Chang K, Phanuphak N, Ratnaratorn N, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Robb ML, Ananworanich J, Spudich S, Valcour V, Paul R, SEARCH 010/RV254 and RV304/SEARCH 013 study teams . Resting-state neural signatures of depressive symptoms in acute HIV. J Neurovirol. 2020 04; 26(2):226-240. View on Pubmed
  29. Chan P, Goh O, Kroon E, Colby D, Sacdalan C, Pinyakorn S, Prueksakaew P, Reiss P, Ananworanich J, Valcour V, Spudich S, Paul R, RV254/SEARCH 010 Research Team . Neuropsychiatric outcomes before and after switching to dolutegravir-based therapy in an acute HIV cohort. AIDS Res Ther. 2020 01 07; 17(1):1. View on Pubmed
  30. Halpin SN, Ge L, Mehta CC, Gustafson D, Robertson KR, Rubin LH, Sharma A, Vance D, Valcour V, Waldrop-Valverde D, Ofotokun I. Psychosocial Resources and Emotions in Women Living With HIV Who Have Cognitive Impairment: Applying the Socio-Emotional Adaptation Theory. Res Theory Nurs Pract. 2020 01 01; 34(1):49-64. View on Pubmed
  31. Massanella M, Bakeman W, Sithinamsuwan P, Fletcher JLK, Chomchey N, Tipsuk S, Chalermchai T, Routy JP, Ananworanich J, Valcour VG, Chomont N. Infrequent HIV Infection of Circulating Monocytes during Antiretroviral Therapy. J Virol. 2019 12 12; 94(1). View on Pubmed
  32. Hellmuth J, Slike BM, Sacdalan C, Best J, Kroon E, Phanuphak N, Fletcher JLK, Prueksakaew P, Jagodzinski LL, Valcour V, Robb M, Ananworanich J, Allen IE, Krebs SJ, Spudich S. Very Early Initiation of Antiretroviral Therapy During Acute HIV Infection Is Associated With Normalized Levels of Immune Activation Markers in Cerebrospinal Fluid but Not in Plasma. J Infect Dis. 2019 11 06; 220(12):1885-1891. View on Pubmed
  33. Chan P, Dumrongpisutikul N, Subra C, Colby DJ, Kroon E, Fletcher J, Sacdalan C, Phanuphak N, Valcour V, Ananworanich J, Trautmann L, Spudich S. Neurosyphilis During Acute HIV Infection: A CNS Immunologic and Virologic Characterization. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):e34-e37. View on Pubmed
  34. Muñoz-Nevárez LA, Imp BM, Eller MA, Kiweewa F, Maswai J, Polyak C, Olwenyi OA, Allen IE, Rono E, Milanini B, Kibuuka H, Ake JA, Eller LA, Valcour VG. Monocyte activation, HIV, and cognitive performance in East Africa. J Neurovirol. 2020 02; 26(1):52-59. View on Pubmed
  35. Tovanabutra S, Sirijatuphat R, Pham PT, Bonar L, Harbolick EA, Bose M, Song H, Chang D, Oropeza C, O'Sullivan AM, Balinang J, Kroon E, Colby DJ, Sacdalan C, Hellmuth J, Chan P, Prueksakaew P, Pinyakorn S, Jagodzinski LL, Sutthichom D, Pattamaswin S, de Souza M, Gramzinski RA, Kim JH, Michael NL, Robb ML, Phanuphak N, Ananworanich J, Valcour V, Kijak GH, Sanders-Buell E, Spudich S, MHRP Viral Sequencing Core , RV254/SEARCH 010 Study Team . Deep Sequencing Reveals Central Nervous System Compartmentalization in Multiple Transmitted/Founder Virus Acute HIV-1 Infection. Cells. 2019 08 15; 8(8). View on Pubmed
  36. Ake JA, Polyak CS, Crowell TA, Kiweewa F, Semwogerere M, Maganga L, Bahemana E, Maswai J, Langat R, Owuoth J, Otieno S, Keshinro B, Esber AL, Liu M, Eller LA, Ganesan K, Parikh AP, Hamm TE, Robb ML, Hickey PW, Valcour VG, Michael NL, African Cohort Study Team . Noninfectious Comorbidity in the African Cohort Study. Clin Infect Dis. 2019 08 01; 69(4):639-647. View on Pubmed
  37. Milanini B, Samboju V, Cobigo Y, Paul R, Javandel S, Hellmuth J, Allen I, Miller B, Valcour V. Longitudinal brain atrophy patterns and neuropsychological performance in older adults with HIV-associated neurocognitive disorder compared with early Alzheimer's disease. Neurobiol Aging. 2019 10; 82:69-76. View on Pubmed
  38. Rubin LH, Springer G, Martin EM, Seaberg EC, Sacktor NC, Levine A, Valcour VG, Young MA, Becker JT, Maki PM. Elevated Depressive Symptoms Are a Stronger Predictor of Executive Dysfunction in HIV-Infected Women Than in Men. J Acquir Immune Defic Syndr. 2019 07 01; 81(3):274-283. View on Pubmed
  39. Hosaka KRJ, Greene M, Premeaux TA, Javandel S, Allen IE, Ndhlovu LC, Valcour V. Geriatric Syndromes in Older Adults Living with HIV and Cognitive Impairment. J Am Geriatr Soc. 2019 09; 67(9):1913-1916. View on Pubmed
  40. Malee KM, Kerr S, Paul R, Puthanakit T, Thongpibul K, Kosalaraksa P, Ounchanum P, Kanjanavanit S, Aurpibul L, Ngampiyaskul C, Luesomboon W, Wongsawat J, Vonthanak S, Ly PS, Chettra K, Suwanlerk T, Sophonphan J, Valcour V, Ananworanich J, Mellins CA, PREDICT Resilience study . Emotional and behavioral resilience among children with perinatally acquired HIV in Thailand and Cambodia. AIDS. 2019 06 01; 33 Suppl 1:S17-S27. View on Pubmed
  41. Meffert SM, Neylan TC, McCulloch CE, Maganga L, Adamu Y, Kiweewa F, Maswai J, Owuoth J, Polyak CS, Ake JA, Valcour VG. East African HIV care: depression and HIV outcomes. Glob Ment Health (Camb). 2019; 6:e9. View on Pubmed
  42. Wade BSC, Valcour VG, Puthanakit T, Saremi A, Gutman BA, Nir TM, Watson C, Aurpibul L, Kosalaraksa P, Ounchanum P, Kerr S, Dumrongpisutikul N, Visrutaratna P, Srinakarin J, Pothisri M, Narr KL, Thompson PM, Ananworanich J, Paul RH, Jahanshad N, PREDICT and Resilience Study Groups . Mapping abnormal subcortical neurodevelopment in a cohort of Thai children with HIV. Neuroimage Clin. 2019; 23:101810. View on Pubmed
  43. Premeaux TA, D'Antoni ML, Abdel-Mohsen M, Pillai SK, Kallianpur KJ, Nakamoto BK, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Gisslén M, Price RW, Valcour V, Ndhlovu LC. Elevated cerebrospinal fluid Galectin-9 is associated with central nervous system immune activation and poor cognitive performance in older HIV-infected individuals. J Neurovirol. 2019 04; 25(2):150-161. View on Pubmed
  44. Narvid J, McCoy D, Dupont SM, Callen A, Tosun D, Hellmuth J, Valcour V. Abnormal Cerebral Perfusion Profile in Older Adults with HIV-Associated Neurocognitive Disorder: Discriminative Power of Arterial Spin-Labeling. AJNR Am J Neuroradiol. 2018 12; 39(12):2211-2217. View on Pubmed
  45. Milanini B, Paul R, Bahemana E, Adamu Y, Kiweewa F, Langat R, Owuoth J, Allen E, Polyak C, Ake J, Valcour V, AFRICOS study Team . Limitations of the International HIV Dementia Scale in the current era. AIDS. 2018 11 13; 32(17):2477-2483. View on Pubmed
  46. Kim EJ, Brown JA, Deng J, Hwang JL, Spina S, Miller ZA, DeMay MG, Valcour V, Karydas A, Ramos EM, Coppola G, Miller BL, Rosen HJ, Seeley WW, Grinberg LT. Mixed TDP-43 proteinopathy and tauopathy in frontotemporal lobar degeneration: nine case series. J Neurol. 2018 Dec; 265(12):2960-2971. View on Pubmed
  47. Hellmuth J, Milanini B, Masliah E, Tartaglia MC, Dunlop MB, Moore DJ, Javandel S, DeVaughn S, Valcour V. A neuropathologic diagnosis of Alzheimer's disease in an older adult with HIV-associated neurocognitive disorder. Neurocase. 2018 08; 24(4):213-219. View on Pubmed
  48. D'Antoni ML, Byron MM, Chan P, Sailasuta N, Sacdalan C, Sithinamsuwan P, Tipsuk S, Pinyakorn S, Kroon E, Slike BM, Krebs SJ, Khadka VS, Chalermchai T, Kallianpur KJ, Robb M, Spudich S, Valcour V, Ananworanich J, Ndhlovu LC, RV254/SEARCH010, SEARCH011, and RV304/SEARCH013 Study Groups . Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities. J Infect Dis. 2018 09 22; 218(9):1453-1463. View on Pubmed
  49. Maki PM, Rubin LH, Springer G, Seaberg EC, Sacktor N, Miller EN, Valcour V, Young MA, Becker JT, Martin EM, Neuropsychology Working Groups of the Women's Interagency HIV Study and the Multicenter AIDS Cohort . Differences in Cognitive Function Between Women and Men With HIV. . 2018 09 01; 79(1):101-107. View on Pubmed
  50. Chan P, Patel P, Hellmuth J, Colby DJ, Kroon E, Sacdalan C, Pinyakorn S, Jagodzinski L, Krebs S, Ananworanich J, Valcour V, Spudich S, RV254/SEARCH 010 Study Team . Distribution of Human Immunodeficiency Virus (HIV) Ribonucleic Acid in Cerebrospinal Fluid and Blood Is Linked to CD4/CD8 Ratio During Acute HIV. J Infect Dis. 2018 08 14; 218(6):937-945. View on Pubmed
  51. Samboju V, Philippi CL, Chan P, Cobigo Y, Fletcher JLK, Robb M, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Paul R, Ananworanich J, Spudich S, Valcour V, SEARCH 010/RV254 , RV304 protocol teams . Structural and functional brain imaging in acute HIV. Neuroimage Clin. 2018; 20:327-335. View on Pubmed
  52. Huck DM, Hanna DB, Rubin LH, Maki P, Valcour V, Springer G, Xue X, Lazar J, Hodis HN, Anastos K, Kaplan RC, Kizer JR. Carotid Artery Stiffness and Cognitive Decline Among Women With or at Risk for HIV Infection. . 2018 07 01; 78(3):338-347. View on Pubmed
  53. Paul R, Prasitsuebsai W, Jahanshad N, Puthanakit T, Thompson P, Aurpibul L, Hansudewechakul R, Kosalaraksa P, Kanjanavanit S, Ngampiyaskul C, Luesomboon W, Lerdlum S, Pothisri M, Visrutaratna P, Valcour V, Nir TM, Saremi A, Kerr S, Ananworanich J, Pediatric Randomized Early versus Deferred Initiation in Cambodia and Thailand (PREDICT) Study Group . Structural Neuroimaging and Neuropsychologic Signatures in Children With Vertically Acquired HIV. Pediatr Infect Dis J. 2018 07; 37(7):662-668. View on Pubmed
  54. Ratto-Kim S, Schuetz A, Sithinamsuwan P, Barber J, Hutchings N, Lerdlum S, Fletcher JLK, Phuang-Ngern Y, Chuenarom W, Tipsuk S, Pothisri M, Jadwattanakul T, Jirajariyavej S, Sajjaweerawan C, Akapirat S, Chalermchai T, Suttichom D, Kaewboon B, Prueksakaew P, Karnsomlap P, Clifford D, Paul RH, de Souza MS, Kim JH, Ananworanich J, Valcour V. Characterization of Cellular Immune Responses in Thai Individuals With and Without HIV-Associated Neurocognitive Disorders. AIDS Res Hum Retroviruses. 2018 08; 34(8):685-689. View on Pubmed
  55. Hsu DC, Sunyakumthorn P, Wegner M, Schuetz A, Silsorn D, Estes JD, Deleage C, Tomusange K, Lakhashe SK, Ruprecht RM, Lombardini E, Im-Erbsin R, Kuncharin Y, Phuang-Ngern Y, Inthawong D, Chuenarom W, Burke R, Robb ML, Ndhlovu LC, Ananworanich J, Valcour V, O'Connell RJ, Spudich S, Michael NL, Vasan S. Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques. J Virol. 2018 06 01; 92(11). View on Pubmed
  56. Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, Valcour VG, Spudich S, Michael NL, Robb ML, Phanuphak N, Ananworanich J, RV254/SEARCH010 Study Group . Acute Retroviral Syndrome Is Associated With High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments. Clin Infect Dis. 2018 05 02; 66(10):1540-1549. View on Pubmed
  57. Paul R, Apornpong T, Prasitsuebsai W, Puthanakit T, Saphonn V, Aurpibul L, Kosalaraksa P, Kanjanavanit S, Luesomboon W, Ngampiyaskul C, Suwanlerk T, Chettra K, Shearer WT, Valcour V, Ananworanich J, Kerr S. Cognition, Emotional Health, and Immunological Markers in Children With Long-Term Nonprogressive HIV. . 2018 04 01; 77(4):417-426. View on Pubmed
  58. Do TC, Kerr SJ, Avihingsanon A, Suksawek S, Klungkang S, Channgam T, Odermatt CC, Maek-A-Nantawat W, Ruxtungtham K, Ananworanich J, Valcour V, Reiss P, Wit FW. HIV-associated cognitive performance and psychomotor impairment in a Thai cohort on long-term cART. J Virus Erad. 2018 Jan 01; 4(1):41-47. View on Pubmed
  59. Chan P, Hellmuth J, Colby D, Kroon E, Sacdalan C, Fletcher J, Patel P, Pinyakorn S, Valcour V, Ananworanich J, Spudich S. Safety of lumbar puncture procedure in an international research setting during acute HIV infection. J Virus Erad. 2018 Jan 01; 4(1):16-20. View on Pubmed
  60. Hellmuth J, Colby D, Valcour V, Suttichom D, Spudich S, Ananworanich J, Prueksakaew P, Sailasuta N, Allen I, Jagodzinski LL, Slike B, Ochi D, Paul R, RV254/SEARCH 010 Study Group . Depression and Anxiety are Common in Acute HIV Infection and Associate with Plasma Immune Activation. AIDS Behav. 2017 Nov; 21(11):3238-3246. View on Pubmed
  61. Clifford KM, Samboju V, Cobigo Y, Milanini B, Marx GA, Hellmuth JM, Rosen HJ, Kramer JH, Allen IE, Valcour VG. Progressive Brain Atrophy Despite Persistent Viral Suppression in HIV Patients Older Than 60 Years. J Acquir Immune Defic Syndr. 2017 11 01; 76(3):289-297. View on Pubmed
  62. Rubin LH, Benning L, Keating SM, Norris PJ, Burke-Miller J, Savarese A, Kumanan KN, Awadalla S, Springer G, Anastos K, Young M, Milam J, Valcour VG, Weber KM, Maki PM. Variability in C-reactive protein is associated with cognitive impairment in women living with and without HIV: a longitudinal study. J Neurovirol. 2018 02; 24(1):41-51. View on Pubmed
  63. Rubin LH, Maki PM, Springer G, Benning L, Anastos K, Gustafson D, Villacres MC, Jiang X, Adimora AA, Waldrop-Valverde D, Vance DE, Bolivar H, Alden C, Martin EM, Valcour VG, Women's Interagency HIV Study . Cognitive trajectories over 4 years among HIV-infected women with optimal viral suppression. Neurology. 2017 Oct 10; 89(15):1594-1603. View on Pubmed
  64. Rubin LH, Cook JA, Springer G, Weber KM, Cohen MH, Martin EM, Valcour VG, Benning L, Alden C, Milam J, Anastos K, Young MA, Gustafson DR, Sundermann EE, Maki PM. Perceived and post-traumatic stress are associated with decreased learning, memory, and fluency in HIV-infected women. AIDS. 2017 11; 31(17):2393-1401. View on Pubmed
  65. Milanini B, Valcour V. Differentiating HIV-Associated Neurocognitive Disorders From Alzheimer's Disease: an Emerging Issue in Geriatric NeuroHIV. Curr HIV/AIDS Rep. 2017 08; 14(4):123-132. View on Pubmed
  66. Kessing CF, Spudich S, Valcour V, Cartwright P, Chalermchai T, Fletcher JL, Takata H, Nichols C, Josey BJ, Slike B, Krebs SJ, Sailsuta N, Lerdlum S, Jagodzinski L, Tipsuk S, Suttichom D, Rattanamanee S, Zetterberg H, Hellmuth J, Phanuphak N, Robb ML, Michael NL, Ananworanich J, Trautmann L. High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection. . 2017 05 01; 75(1):108-117. View on Pubmed
  67. Agsalda-Garcia MA, Sithinamsuwan P, Valcour VG, Chalermchai T, Tipsuk S, Kuroda J, Nakamura C, Ananworanich J, Zhang G, Schuetz A, Slike BM, Shiramizu B, SEARCH 011 Study Group . Brief Report: CD14+ Enriched Peripheral Cells Secrete Cytokines Unique to HIV-Associated Neurocognitive Disorders. . 2017 04 01; 74(4):454-458. View on Pubmed
  68. Vance DE, Rubin LH, Valcour V, Waldrop-Valverde D, Maki PM. Erratum to: Aging and Neurocognitive Functioning in HIV-Infected Women: a Review of the Literature Involving the Women's Interagency HIV Study. Curr HIV/AIDS Rep. 2017 02; 14(1):38. View on Pubmed
  69. Milanini B, Catella S, Perkovich B, Esmaeili-Firidouni P, Wendelken L, Paul R, Greene M, Ketelle R, Valcour V. Psychiatric symptom burden in older people living with HIV with and without cognitive impairment: the UCSF HIV over 60 cohort study. AIDS Care. 2017 09; 29(9):1178-1185. View on Pubmed
  70. Watson C, Busovaca E, Foley JM, Allen IE, Schwarz CG, Jahanshad N, Nir TM, Esmaeili-Firidouni P, Milanini B, Rosen H, Carmichael OT, Thompson PM, Valcour VG. White matter hyperintensities correlate to cognition and fiber tract integrity in older adults with HIV. J Neurovirol. 2017 06; 23(3):422-429. View on Pubmed
  71. Peluso MJ, Valcour V, Phanuphak N, Ananworanich J, Fletcher JL, Chalermchai T, Krebs SJ, Robb ML, Hellmuth J, Gisslén M, Zetterberg H, Spudich S, RV254SEARCH 010, RV304SEARCH 013, and SEARCH 011 Study Teams . Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection. AIDS. 2017 01 14; 31(2):247-252. View on Pubmed
  72. Vance DE, Rubin LH, Valcour V, Waldrop-Valverde D, Maki PM. Aging and Neurocognitive Functioning in HIV-Infected Women: a Review of the Literature Involving the Women's Interagency HIV Study. Curr HIV/AIDS Rep. 2016 12; 13(6):399-411. View on Pubmed
  73. Wendelken LA, Jahanshad N, Rosen HJ, Busovaca E, Allen I, Coppola G, Adams C, Rankin KP, Milanini B, Clifford K, Wojta K, Nir TM, Gutman BA, Thompson PM, Valcour V. ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60. . 2016 Dec 01; 73(4):426-432. View on Pubmed
  74. Kamtchum-Tatuene J, Wan Sulaiman WA, Lekoubou A, Hellmuth J, Valcour V, Spudich S. Neurologic signs and symptoms frequently manifest in acute HIV infection. Neurology. 2016 11 29; 87(22):2386. View on Pubmed
  75. Imp BM, Rubin LH, Tien PC, Plankey MW, Golub ET, French AL, Valcour VG. Monocyte Activation Is Associated With Worse Cognitive Performance in HIV-Infected Women With Virologic Suppression. J Infect Dis. 2017 Jan 01; 215(1):114-121. View on Pubmed
  76. Sereti I, Krebs SJ, Phanuphak N, Fletcher JL, Slike B, Pinyakorn S, O'Connell RJ, Rupert A, Chomont N, Valcour V, Kim JH, Robb ML, Michael NL, Douek DC, Ananworanich J, Utay NS, RV254/SEARCH 010, RV304/SEARCH 013 and SEARCH 011 protocol teams . Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection. Clin Infect Dis. 2017 Jan 15; 64(2):124-131. View on Pubmed
  77. Corley MJ, Dye C, D'Antoni ML, Byron MM, Yo KL, Lum-Jones A, Nakamoto B, Valcour V, SahBandar I, Shikuma CM, Ndhlovu LC, Maunakea AK. Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment. Sci Rep. 2016 09 15; 6:33310. View on Pubmed
  78. Zhang Y, Kwon D, Esmaeili-Firidouni P, Pfefferbaum A, Sullivan EV, Javitz H, Valcour V, Pohl KM. Extracting patterns of morphometry distinguishing HIV associated neurodegeneration from mild cognitive impairment via group cardinality constrained classification. Hum Brain Mapp. 2016 12; 37(12):4523-4538. View on Pubmed
  79. Chan P, Hellmuth J, Spudich S, Valcour V. Cognitive Impairment and Persistent CNS Injury in Treated HIV. Curr HIV/AIDS Rep. 2016 08; 13(4):209-17. View on Pubmed
  80. Muir R, Metcalf T, Tardif V, Takata H, Phanuphak N, Kroon E, Colby DJ, Trichavaroj R, Valcour V, Robb ML, Michael NL, Ananworanich J, Trautmann L, Haddad EK, RV254/SEARCH010 RV304/SEARCH 013 Study Groups . Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection. PLoS Pathog. 2016 07; 12(7):e1005777. View on Pubmed
  81. Valcour VG, Rubin LH, Obasi MU, Maki PM, Peters MG, Levin S, Crystal HA, Young MA, Mack WJ, Cohen MH, Pierce CB, Adimora AA, Tien PC, Women's Interagency HIV Study Protocol Team . Liver Fibrosis Linked to Cognitive Performance in HIV and Hepatitis C. . 2016 07 01; 72(3):266-73. View on Pubmed
  82. Krebs SJ, Slike BM, Sithinamsuwan P, Allen IE, Chalermchai T, Tipsuk S, Phanuphak N, Jagodzinski L, Kim JH, Ananworanich J, Marovich MA, Valcour VG, SEARCH 011 study team . Sex differences in soluble markers vary before and after the initiation of antiretroviral therapy in chronically HIV-infected individuals. AIDS. 2016 06 19; 30(10):1533-42. View on Pubmed
  83. Hellmuth J, Fletcher JL, Valcour V, Kroon E, Ananworanich J, Intasan J, Lerdlum S, Narvid J, Pothisri M, Allen I, Krebs SJ, Slike B, Prueksakaew P, Jagodzinski LL, Puttamaswin S, Phanuphak N, Spudich S, SEARCH 010/RV254 Study Group . Neurologic signs and symptoms frequently manifest in acute HIV infection. Neurology. 2016 07 12; 87(2):148-54. View on Pubmed
  84. Sailasuta N, Ananworanich J, Lerdlum S, Sithinamsuwan P, Fletcher JL, Tipsuk S, Pothisri M, Jadwattanakul T, Jirajariyavej S, Chalermchai T, Catella S, Busovaca E, Desai A, Paul R, Valcour V, SEARCH 011 Study Group . Neuronal-Glia Markers by Magnetic Resonance Spectroscopy in HIV Before and After Combination Antiretroviral Therapy. . 2016 Jan 01; 71(1):24-30. View on Pubmed
  85. Ananworanich J, Sacdalan CP, Pinyakorn S, Chomont N, de Souza M, Luekasemsuk T, Schuetz A, Krebs SJ, Dewar R, Jagodzinski L, Ubolyam S, Trichavaroj R, Tovanabutra S, Spudich S, Valcour V, Sereti I, Michael N, Robb M, Phanuphak P, Kim JH, Phanuphak N. Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection. J Virus Erad. 2016; 2:43-48. View on Pubmed
  86. Kore I, Ananworanich J, Valcour V, Fletcher JL, Chalermchai T, Paul R, Reynolds J, Tipsuk S, Ubolyam S, Rattanamanee S, Jagodzinski L, Kim J, Spudich S, RV254/SEARCH 010 Study Group . Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy. . 2015 Dec 01; 70(4):393-9. View on Pubmed
  87. Valcour VG, Spudich SS, Sailasuta N, Phanuphak N, Lerdlum S, Fletcher JL, Kroon ED, Jagodzinski LL, Allen IE, Adams CL, Prueksakaew P, Slike BM, Hellmuth JM, Kim JH, Ananworanich J, SEARCH 010/RV 254 Study Group . Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV. PLoS One. 2015; 10(11):e0142600. View on Pubmed
  88. Wade BS, Valcour VG, Wendelken-Riegelhaupt L, Esmaeili-Firidouni P, Joshi SH, Gutman BA, Thompson PM. Mapping abnormal subcortical brain morphometry in an elderly HIV+ cohort. Neuroimage Clin. 2015; 9:564-73. View on Pubmed
  89. Rubin LH, Pyra M, Cook JA, Weber KM, Cohen MH, Martin E, Valcour V, Milam J, Anastos K, Young MA, Alden C, Gustafson DR, Maki PM. Post-traumatic stress is associated with verbal learning, memory, and psychomotor speed in HIV-infected and HIV-uninfected women. J Neurovirol. 2016 Apr; 22(2):159-69. View on Pubmed
  90. Ndhlovu LC, D'Antoni ML, Ananworanich J, Byron MM, Chalermchai T, Sithinamsuwan P, Tipsuk S, Ho E, Slike BM, Schuetz A, Zhang G, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Valcour V, SEARCH 011 study group . Loss of CCR2 expressing non-classical monocytes are associated with cognitive impairment in antiretroviral therapy-naïve HIV-infected Thais. J Neuroimmunol. 2015 Nov 15; 288:25-33. View on Pubmed
  91. Jahanshad N, Couture MC, Prasitsuebsai W, Nir TM, Aurpibul L, Thompson PM, Pruksakaew K, Lerdlum S, Visrutaratna P, Catella S, Desai A, Kerr SJ, Puthanakit T, Paul R, Ananworanich J, Valcour VG, SEARCH 012 and PREDICT Study Groups . Brain Imaging and Neurodevelopment in HIV-uninfected Thai Children Born to HIV-infected Mothers. Pediatr Infect Dis J. 2015 Sep; 34(9):e211-6. View on Pubmed
  92. Guha A, Wang L, Tanenbaum A, Esmaeili-Firidouni P, Wendelken LA, Busovaca E, Clifford K, Desai A, Ances BM, Valcour V. Intrinsic network connectivity abnormalities in HIV-infected individuals over age 60. J Neurovirol. 2016 Feb; 22(1):80-7. View on Pubmed
  93. Greene M, Covinsky KE, Valcour V, Miao Y, Madamba J, Lampiris H, Cenzer IS, Martin J, Deeks SG. Geriatric Syndromes in Older HIV-Infected Adults. . 2015 Jun 01; 69(2):161-7. View on Pubmed
  94. Peluso MJ, Valcour V, Ananworanich J, Sithinamsuwan P, Chalermchai T, Fletcher JL, Lerdlum S, Chomchey N, Slike B, Sailasuta N, Gisslén M, Zetterberg H, Spudich S, RV254/SEARCH 010 and SEARCH 011 Study Teams . Absence of Cerebrospinal Fluid Signs of Neuronal Injury Before and After Immediate Antiretroviral Therapy in Acute HIV Infection. J Infect Dis. 2015 Dec 01; 212(11):1759-67. View on Pubmed
  95. Hellmuth J, Valcour V, Spudich S. CNS reservoirs for HIV: implications for eradication. J Virus Erad. 2015 Apr; 1(2):67-71. View on Pubmed
  96. Wade BS, Valcour VG, Wendelken-Riegelhaupt L, Esmaeili-Firidouni P, Joshi SH, Wang Y, Thompson PM. MAPPING ABNORMAL SUBCORTICAL BRAIN MORPHOMETRY IN AN ELDERLY HIV+ COHORT. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:971-975. View on Pubmed
  97. Rubin LH, Cook JA, Weber KM, Cohen MH, Martin E, Valcour V, Milam J, Anastos K, Young MA, Alden C, Gustafson DR, Maki PM. The association of perceived stress and verbal memory is greater in HIV-infected versus HIV-uninfected women. J Neurovirol. 2015 Aug; 21(4):422-32. View on Pubmed
  98. Wade BS, Valcour V, Busovaca E, Esmaeili-Firidouni P, Joshi SH, Wang Y, Thompson PM. Subcortical shape and volume abnormalities in an elderly HIV+ cohort. Proc SPIE Int Soc Opt Eng. 2015 Mar 17; 9417. View on Pubmed
  99. Valcour V, Rubin LH, Tien P, Anastos K, Young M, Mack W, Cohen M, Golub ET, Crystal H, Maki PM. Human immunodeficiency virus (HIV) modulates the associations between insulin resistance and cognition in the current combination antiretroviral therapy (cART) era: a study of the Women's Interagency HIV Study (WIHS). J Neurovirol. 2015 Aug; 21(4):415-21. View on Pubmed
  100. Heaps JM, Sithinamsuwan P, Paul R, Lerdlum S, Pothisri M, Clifford D, Tipsuk S, Catella S, Busovaca E, Fletcher JL, Raudabaugh B, Ratto-Kim S, Valcour V, Ananworanich J, SEARCH 007/011 study groups . Association between brain volumes and HAND in cART-naïve HIV+ individuals from Thailand. J Neurovirol. 2015 Apr; 21(2):105-12. View on Pubmed
  101. Maki PM, Rubin LH, Valcour V, Martin E, Crystal H, Young M, Weber KM, Manly J, Richardson J, Alden C, Anastos K. Cognitive function in women with HIV: findings from the Women's Interagency HIV Study. Neurology. 2015 Jan 20; 84(3):231-40. View on Pubmed
  102. Ananworanich J, Datta AA, Fletcher JL, Townamchai N, Chomchey N, Kroon E, Sereti I, Valcour V, Kim JH. Acute tubular nephropathy in a patient with acute HIV infection: review of the literature. AIDS Res Ther. 2014; 11:34. View on Pubmed
  103. Paul RH, Joska JA, Woods C, Seedat S, Engelbrecht S, Hoare J, Heaps J, Valcour V, Ances B, Baker LM, Salminen LE, Stein DJ. Impact of the HIV Tat C30C31S dicysteine substitution on neuropsychological function in patients with clade C disease. J Neurovirol. 2014 Dec; 20(6):627-35. View on Pubmed
  104. Hellmuth J, Milanini B, Valcour V. Interactions between ageing and NeuroAIDS. Curr Opin HIV AIDS. 2014 Nov; 9(6):527-32. View on Pubmed
  105. Milanini B, Wendelken LA, Esmaeili-Firidouni P, Chartier M, Crouch PC, Valcour V. The Montreal cognitive assessment to screen for cognitive impairment in HIV patients older than 60 years. . 2014 Sep 01; 67(1):67-70. View on Pubmed
  106. Kallianpur KJ, Valcour VG, Lerdlum S, Busovaca E, Agsalda M, Sithinamsuwan P, Chalermchai T, Fletcher JL, Tipsuk S, Shikuma CM, Shiramizu BT, Ananworanich J, SEARCH 011 study group . HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patients naive to combination antiretroviral therapy. AIDS. 2014 Jul 17; 28(11):1619-24. View on Pubmed
  107. Hanna RF, Ward TJ, Chow DS, Lagana SM, Moreira RK, Emond JC, Weintraub JL, Prince MR. An evaluation of the sensitivity of MRI at detecting hepatocellular carcinoma in cirrhotic patients utilizing an explant reference standard. Clin Imaging. 2014 Sep-Oct; 38(5):693-7. View on Pubmed
  108. Kerr SJ, Puthanakit T, Vibol U, Aurpibul L, Vonthanak S, Kosalaraksa P, Kanjanavanit S, Hansudewechakul R, Wongsawat J, Luesomboon W, Ratanadilok K, Prasitsuebsai W, Pruksakaew K, van der Lugt J, Paul R, Ananworanich J, Valcour V, SEARCH 012 Study Team . Neurodevelopmental outcomes in HIV-exposed-uninfected children versus those not exposed to HIV. AIDS Care. 2014; 26(11):1327-35. View on Pubmed
  109. Greene M, Steinman MA, McNicholl IR, Valcour V. Polypharmacy, drug-drug interactions, and potentially inappropriate medications in older adults with human immunodeficiency virus infection. J Am Geriatr Soc. 2014 Mar; 62(3):447-53. View on Pubmed
  110. Sithinamsuwan P, Hutchings N, Ananworanich J, Wendelken L, Saengtawan P, Paul R, Chomchey N, Fletcher JL, Chalermchai T, Valcour V. Practice effect and normative data of an HIV-specific neuropsychological testing battery among healthy Thais. J Med Assoc Thai. 2014 Feb; 97 Suppl 2:S222-33. View on Pubmed
  111. Gustafson DR, Mielke MM, Tien PC, Valcour V, Cohen M, Anastos K, Liu C, Pearce L, Golub ET, Minkoff H, Crystal HA. Anthropometric measures and cognition in middle-aged HIV-infected and uninfected women. The Women's Interagency HIV Study. J Neurovirol. 2013 Dec; 19(6):574-85. View on Pubmed
  112. Valcour VG, Ananworanich J, Agsalda M, Sailasuta N, Chalermchai T, Schuetz A, Shikuma C, Liang CY, Jirajariyavej S, Sithinamsuwan P, Tipsuk S, Clifford DB, Paul R, Fletcher JL, Marovich MA, Slike BM, DeGruttola V, Shiramizu B, SEARCH 011 Protocol Team . HIV DNA reservoir increases risk for cognitive disorders in cART-naïve patients. PLoS One. 2013; 8(7):e70164. View on Pubmed
  113. Shikuma CM, McArthur JC, Ebenezer GJ, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Valcour VG, Bennett K, Phanuphak N, SEARCH 014 Protocol Team . Ethnic differences in epidermal nerve fiber density. Muscle Nerve. 2013 Sep; 48(3):462-4. View on Pubmed
  114. Gardner RC, Valcour V, Yaffe K. Dementia in the oldest old: a multi-factorial and growing public health issue. Alzheimers Res Ther. 2013; 5(4):27. View on Pubmed
  115. Valcour VG. HIV, aging, and cognition: emerging issues. Top Antivir Med. 2013 Jul-Aug; 21(3):119-23. View on Pubmed
  116. Puthanakit T, Ananworanich J, Vonthanak S, Kosalaraksa P, Hansudewechakul R, van der Lugt J, Kerr SJ, Kanjanavanit S, Ngampiyaskul C, Wongsawat J, Luesomboon W, Vibol U, Pruksakaew K, Suwarnlerk T, Apornpong T, Ratanadilok K, Paul R, Mofenson LM, Fox L, Valcour V, Brouwers P, Ruxrungtham K, PREDICT Study Group . Cognitive function and neurodevelopmental outcomes in HIV-infected Children older than 1 year of age randomized to early versus deferred antiretroviral therapy: the PREDICT neurodevelopmental study. Pediatr Infect Dis J. 2013 May; 32(5):501-8. View on Pubmed
  117. Meyer VJ, Rubin LH, Martin E, Weber KM, Cohen MH, Golub ET, Valcour V, Young MA, Crystal H, Anastos K, Aouizerat BE, Milam J, Maki PM. HIV and recent illicit drug use interact to affect verbal memory in women. . 2013 May 01; 63(1):67-76. View on Pubmed
  118. Kallianpur KJ, Shikuma C, Kirk GR, Shiramizu B, Valcour V, Chow D, Souza S, Nakamoto B, Sailasuta N. Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter. Neurology. 2013 May 07; 80(19):1792-9. View on Pubmed
  119. Greene M, Justice AC, Lampiris HW, Valcour V. Management of human immunodeficiency virus infection in advanced age. JAMA. 2013 Apr 03; 309(13):1397-405. View on Pubmed
  120. Chiao S, Rosen HJ, Nicolas K, Wendelken LA, Alcantar O, Rankin KP, Miller B, Valcour V. Deficits in self-awareness impact the diagnosis of asymptomatic neurocognitive impairment in HIV. AIDS Res Hum Retroviruses. 2013 Jun; 29(6):949-56. View on Pubmed
  121. Chalermchai T, Valcour V, Sithinamsuwan P, Pinyakorn S, Clifford D, Paul RH, Tipsuk S, Fletcher JL, Degruttola V, Ratto-Kim S, Hutchings N, Shikuma C, Ananworanich J, SEARCH 007 and 011 study groups . Trail Making Test A improves performance characteristics of the International HIV Dementia Scale to identify symptomatic HAND. J Neurovirol. 2013 Apr; 19(2):137-43. View on Pubmed
  122. Nir TM, Jahanshad N, Busovaca E, Wendelken L, Nicolas K, Thompson PM, Valcour VG. Mapping white matter integrity in elderly people with HIV. Hum Brain Mapp. 2014 Mar; 35(3):975-92. View on Pubmed
  123. Joseph J, Achim CL, Boivin MJ, Brew BJ, Clifford DB, Colosi DA, Ellis RJ, Heaton RK, Gallo-Diop A, Grant I, Kanmogne GD, Kumar M, Letendre S, Marcotte TD, Nath A, Pardo CA, Paul RH, Pulliam L, Robertson K, Royal W, Sacktor N, Sithinamsuwan P, Smith DM, Valcour V, Wigdahl B, Wood C. Global NeuroAIDS roundtable. J Neurovirol. 2013 Feb; 19(1):1-9. View on Pubmed
  124. Phanuphak N, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Kerr SJ, Chomchey N, Hongchookiat P, Mathajittiphun P, Pinyakorn S, Rungrojrat P, Praihirunyakit P, Gerschenson M, Phanuphak P, Valcour V, Kim JH, Shikuma C, SEARCH 003 Study Group . A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine. Antivir Ther. 2012; 17(8):1521-31. View on Pubmed
  125. Sailasuta N, Ross W, Ananworanich J, Chalermchai T, DeGruttola V, Lerdlum S, Pothisri M, Busovaca E, Ratto-Kim S, Jagodzinski L, Spudich S, Michael N, Kim JH, Valcour V, RV254/SEARCH 010 protocol teams . Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection. PLoS One. 2012; 7(11):e49272. View on Pubmed
  126. Heaps J, Valcour V, Chalermchai T, Paul R, Rattanamanee S, Siangphoe U, Sithinamsuwan P, Chairangsaris P, Nidhinandana S, Tipsuk S, Suttichom D, Fletcher J, Shikuma C, Ananworanich J. Development of normative neuropsychological performance in Thailand for the assessment of HIV-associated neurocognitive disorders. J Clin Exp Neuropsychol. 2013; 35(1):1-8. View on Pubmed
  127. Shikuma CM, Nakamoto B, Shiramizu B, Liang CY, DeGruttola V, Bennett K, Paul R, Kallianpur K, Chow D, Gavegnano C, Hurwitz SJ, Schinazi RF, Valcour VG. Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV. Antivir Ther. 2012; 17(7):1233-42. View on Pubmed
  128. Bunupuradah T, Chetchotisakd P, Jirajariyavej S, Valcour V, Bowonwattanuwong C, Munsakul W, Klinbuayaem V, Prasithsirikul W, Sophonphan J, Mahanontharit A, Hirschel B, Bhakeecheep S, Ruxrungtham K, Ananworanich J, HIV STAR Study Group . Neurocognitive impairment in patients randomized to second-line lopinavir/ritonavir-based antiretroviral therapy vs. lopinavir/ritonavir monotherapy. J Neurovirol. 2012 Dec; 18(6):479-87. View on Pubmed
  129. High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, Deren S, Effros RB, Gebo K, Goronzy JJ, Justice AC, Landay A, Levin J, Miotti PG, Munk RJ, Nass H, Rinaldo CR, Shlipak MG, Tracy R, Valcour V, Vance DE, Walston JD, Volberding P, OAR Working Group on HIV and Aging . HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. . 2012 Jul 01; 60 Suppl 1:S1-18. View on Pubmed
  130. Nakamoto BK, Jahanshad N, McMurtray A, Kallianpur KJ, Chow DC, Valcour VG, Paul RH, Marotz L, Thompson PM, Shikuma CM. Cerebrovascular risk factors and brain microstructural abnormalities on diffusion tensor images in HIV-infected individuals. J Neurovirol. 2012 Aug; 18(4):303-12. View on Pubmed
  131. Valcour V, Chalermchai T, Sailasuta N, Marovich M, Lerdlum S, Suttichom D, Suwanwela NC, Jagodzinski L, Michael N, Spudich S, van Griensven F, de Souza M, Kim J, Ananworanich J, RV254/SEARCH 010 Study Group . Central nervous system viral invasion and inflammation during acute HIV infection. J Infect Dis. 2012 Jul 15; 206(2):275-82. View on Pubmed
  132. Wendelken LA, Valcour V. Impact of HIV and aging on neuropsychological function. J Neurovirol. 2012 Aug; 18(4):256-63. View on Pubmed
  133. Ananworanich J, Schuetz A, Vandergeeten C, Sereti I, de Souza M, Rerknimitr R, Dewar R, Marovich M, van Griensven F, Sekaly R, Pinyakorn S, Phanuphak N, Trichavaroj R, Rutvisuttinunt W, Chomchey N, Paris R, Peel S, Valcour V, Maldarelli F, Chomont N, Michael N, Phanuphak P, Kim JH, RV254/SEARCH 010 Study Group . Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. PLoS One. 2012; 7(3):e33948. View on Pubmed
  134. Crystal H, Kleyman I, Anastos K, Lazar J, Cohen M, Liu C, Pearce L, Golub E, Valcour V, Ho A, Strickler H, Peters M, Kovacs A, Holman S, Kreek MJ, Manly J. Effects of hepatitis C and HIV on cognition in women: data from the Women's Interagency HIV Study. . 2012 Feb 01; 59(2):149-54. View on Pubmed
  135. Kusao I, Shiramizu B, Liang CY, Grove J, Agsalda M, Troelstrup D, Velasco VN, Marshall A, Whitenack N, Shikuma C, Valcour V. Cognitive performance related to HIV-1-infected monocytes. J Neuropsychiatry Clin Neurosci. 2012; 24(1):71-80. View on Pubmed
  136. Jahanshad N, Valcour VG, Nir TM, Kohannim O, Busovaca E, Nicolas K, Thompson PM. Disrupted brain networks in the aging HIV+ population. Brain Connect. 2012; 2(6):335-44. View on Pubmed
  137. Shiramizu B, Ananworanich J, Chalermchai T, Siangphoe U, Troelstrup D, Shikuma C, De Grutolla V, Sithinamsuwan P, Praihirunkit P, Rattanamanee S, Valcour V, SEARCH 001.1 Study Group . Failure to clear intra-monocyte HIV infection linked to persistent neuropsychological testing impairment after first-line combined antiretroviral therapy. J Neurovirol. 2012 Feb; 18(1):69-73. View on Pubmed
  138. Valcour VG. Evaluating cognitive impairment in the clinical setting: practical screening and assessment tools. Top Antivir Med. 2011 Dec; 19(5):175-80. View on Pubmed
  139. Shimizu SM, Chow DC, Valcour V, Masaki K, Nakamoto B, Kallianpur KJ, Shikuma C. The Impact of Depressive Symptoms on Neuropsychological Performance Tests in HIV-Infected Individuals: A Study of the Hawaii Aging with HIV Cohort. World J AIDS. 2011 Dec 01; 1(4):139-145. View on Pubmed
  140. Kallianpur KJ, Kirk GR, Sailasuta N, Valcour V, Shiramizu B, Nakamoto BK, Shikuma C. Regional cortical thinning associated with detectable levels of HIV DNA. Cereb Cortex. 2012 Sep; 22(9):2065-75. View on Pubmed
  141. Crystal HA, Weedon J, Holman S, Manly J, Valcour V, Cohen M, Anastos K, Liu C, Mack WJ, Golub E, Lazar J, Ho A, Kreek MJ, Kaplan RC. Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women. J Neurovirol. 2011 Oct; 17(5):469-76. View on Pubmed
  142. Valcour V, Maki P, Bacchetti P, Anastos K, Crystal H, Young M, Mack WJ, Cohen M, Golub ET, Tien PC. Insulin resistance and cognition among HIV-infected and HIV-uninfected adult women: the Women's Interagency HIV Study. AIDS Res Hum Retroviruses. 2012 May; 28(5):447-53. View on Pubmed
  143. Valcour V, Paul R, Chiao S, Wendelken LA, Miller B. Screening for cognitive impairment in human immunodeficiency virus. Clin Infect Dis. 2011 Oct; 53(8):836-42. View on Pubmed
  144. Nakamoto BK, Valcour VG, Kallianpur K, Liang CY, McMurtray A, Chow D, Kappenburg E, Shikuma CM. Impact of cerebrovascular disease on cognitive function in HIV-infected patients. . 2011 Jul 01; 57(3):e66-8. View on Pubmed
  145. Perissinotto CM, Valcour V. Preventing dementia: is there hope for progress? Am Fam Physician. 2011 May 01; 83(9):1034-5. View on Pubmed
  146. Valcour V, Sithinamsuwan P, Letendre S, Ances B. Pathogenesis of HIV in the central nervous system. Curr HIV/AIDS Rep. 2011 Mar; 8(1):54-61. View on Pubmed
  147. Valcour V, Paul R, Neuhaus J, Shikuma C. The Effects of Age and HIV on Neuropsychological Performance. J Int Neuropsychol Soc. 2011 Jan; 17(1):190-5. View on Pubmed
  148. Crystal HA, Hamon S, Randesi M, Cook J, Anastos K, Lazar J, Liu C, Pearce L, Golub E, Valcour V, Weber KM, Holman S, Ho A, Kreek MJ. A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women. Addict Biol. 2012 Jan; 17(1):181-91. View on Pubmed
  149. Joska JA, Combrinck M, Valcour VG, Hoare J, Leisegang F, Mahne AC, Myer L, Stein DJ. Association between apolipoprotein E4 genotype and human immunodeficiency virus-associated dementia in younger adults starting antiretroviral therapy in South Africa. J Neurovirol. 2010 Oct; 16(5):377-83. View on Pubmed
  150. Nakamoto BK, McMurtray A, Davis J, Valcour V, Watters MR, Shiramizu B, Chow DC, Kallianpur K, Shikuma CM. Incident neuropathy in HIV-infected patients on HAART. AIDS Res Hum Retroviruses. 2010 Jul; 26(7):759-65. View on Pubmed
  151. Valcour VG, Shiramizu BT, Shikuma CM. HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications. J Leukoc Biol. 2010 Apr; 87(4):621-6. View on Pubmed
  152. Pumpradit W, Ananworanich J, Lolak S, Shikuma C, Paul R, Siangphoe U, Chaoniti N, Kaew-On P, Paris R, Ruxrungtham K, Valcour V, Southeast Asia Research Collaboration with Hawaii (SEARCH) 005 Protocol Team . Neurocognitive impairment and psychiatric comorbidity in well-controlled human immunodeficiency virus-infected Thais from the 2NN Cohort Study. J Neurovirol. 2010 Feb; 16(1):76-82. View on Pubmed
  153. Valcour V. Aging with HIV. Lessons from CROI 2009. Posit Aware. 2009 May-Jun; 20(3):37-9. View on Pubmed
  154. Valcour VG, Shiramizu BT, Sithinamsuwan P, Nidhinandana S, Ratto-Kim S, Ananworanich J, Siangphoe U, Kim JH, de Souza M, Degruttola V, Paul RH, Shikuma CM, Southeast Asia Research Collaboration with the University of Hawaii 001 protocol team . HIV DNA and cognition in a Thai longitudinal HAART initiation cohort: the SEARCH 001 Cohort Study. Neurology. 2009 Mar 17; 72(11):992-8. View on Pubmed
  155. Valcour V, Yeh TM, Bartt R, Clifford D, Gerschenson M, Evans SR, Cohen BA, Ebenezer GJ, Hauer P, Millar L, Gould M, Tran P, Shikuma C, Souza S, McArthur JC, AIDS Clinical Trials Group (ACTG) 5157 protocol team . Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection. HIV Med. 2009 Feb; 10(2):103-10. View on Pubmed
  156. Shiramizu B, Williams AE, Shikuma C, Valcour V. Amount of HIV DNA in peripheral blood mononuclear cells is proportional to the severity of HIV-1-associated neurocognitive disorders. J Neuropsychiatry Clin Neurosci. 2009; 21(1):68-74. View on Pubmed
  157. Sithinamsuwan P, Punthanamongkol S, Valcour V, Onsanit S, Nidhinandana S, Thitivichianlert S, Shikuma C. Frequency and characteristics of HIV-associated sensory neuropathy among HIV patients in Bangkok, Thailand. . 2008 Dec 01; 49(4):456-8. View on Pubmed
  158. Valcour V, Watters MR, Williams AE, Sacktor N, McMurtray A, Shikuma C. Aging exacerbates extrapyramidal motor signs in the era of highly active antiretroviral therapy. J Neurovirol. 2008 Oct; 14(5):362-7. View on Pubmed
  159. Valcour V, Shiramizu B, Shikuma C. Frequency of apolipoprotein E4 among older compared with younger HIV patients: support for detrimental effect of E4 on survival. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):E66; author reply E67-8. View on Pubmed
  160. McMurtray A, Nakamoto B, Shikuma C, Valcour V. Cortical atrophy and white matter hyperintensities in HIV: the Hawaii Aging with HIV Cohort Study. J Stroke Cerebrovasc Dis. 2008 Jul-Aug; 17(4):212-7. View on Pubmed
  161. Valcour V, Haman A, Cornes S, Lawall C, Parsa AT, Glaser C, Yagi S, Tihan T, Bhatnagar J, Geschwind M, Vanderbilt Continuing Medical Education online . A case of enteroviral meningoencephalitis presenting as rapidly progressive dementia. Nat Clin Pract Neurol. 2008 Jul; 4(7):399-403. View on Pubmed
  162. Ratto-Kim S, Chuenchitra T, Pulliam L, Paris R, Sukwit S, Gongwon S, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Shiramizu BT, de Souza MS, Chitpatima ST, Sun B, Rempel H, Nitayaphan S, Williams K, Kim JH, Shikuma CM, Valcour VG, Southeast Asia Research Collaboration with the University of Hawaii (SEARCH) 001 protocol team . Expression of monocyte markers in HIV-1 infected individuals with or without HIV associated dementia and normal controls in Bangkok Thailand. J Neuroimmunol. 2008 Mar; 195(1-2):100-7. View on Pubmed
  163. Evans SR, Yeh TM, Sacktor N, Clifford DB, Simpson D, Miller EN, Ellis RJ, Valcour V, Marra CM, Millar L, Schifitto G, AIDS Clinical Trials Group and the Neurologic AIDS Research Consortium . Selegiline transdermal system (STS) for HIV-associated cognitive impairment: open-label report of ACTG 5090. HIV Clin Trials. 2007 Nov-Dec; 8(6):437-46. View on Pubmed
  164. Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, Pulliam L, Robertson KR, Sacktor N, Valcour V, Wojna VE. Updated research nosology for HIV-associated neurocognitive disorders. Neurology. 2007 Oct 30; 69(18):1789-99. View on Pubmed
  165. Schifitto G, Zhang J, Evans SR, Sacktor N, Simpson D, Millar LL, Hung VL, Miller EN, Smith E, Ellis RJ, Valcour V, Singer E, Marra CM, Kolson D, Weihe J, Remmel R, Katzenstein D, Clifford DB, ACTG A5090 Team . A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment. Neurology. 2007 Sep 25; 69(13):1314-21. View on Pubmed
  166. McMurtray A, Nakamoto B, Shikuma C, Valcour V. Small-vessel vascular disease in human immunodeficiency virus infection: the Hawaii aging with HIV cohort study. Cerebrovasc Dis. 2007; 24(2-3):236-41. View on Pubmed
  167. Zhou L, Kitch DW, Evans SR, Hauer P, Raman S, Ebenezer GJ, Gerschenson M, Marra CM, Valcour V, Diaz-Arrastia R, Goodkin K, Millar L, Shriver S, Asmuth DM, Clifford DB, Simpson DM, McArthur JC, NARC and ACTG A5117 Study Group . Correlates of epidermal nerve fiber densities in HIV-associated distal sensory polyneuropathy. Neurology. 2007 Jun 12; 68(24):2113-9. View on Pubmed
  168. Sacktor N, Skolasky R, Selnes OA, Watters M, Poff P, Shiramizu B, Shikuma C, Valcour V. Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals. J Neurovirol. 2007 Jun; 13(3):203-9. View on Pubmed
  169. Valcour VG, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Ratto-Kim S, Apateerapong W, Shiramizu BT, Desouza MS, Chitpatima ST, Watt G, Chuenchitra T, Robertson KR, Paul RH, McArthur JC, Kim JH, Shikuma CM. Neuropsychological abnormalities in patients with dementia in CRF 01_AE HIV-1 infection. Neurology. 2007 Feb 13; 68(7):525-7. View on Pubmed
  170. Shiramizu B, Paul R, Williams A, Shikuma C, Watters M, Grove J, Valcour V. HIV proviral DNA associated with decreased neuropsychological function. J Neuropsychiatry Clin Neurosci. 2007; 19(2):157-63. View on Pubmed
  171. Shiramizu B, Ratto-Kim S, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Watt G, deSouza M, Chuenchitra T, Sukwit S, Chitpatima S, Robertson K, Paul R, Shikuma C, Valcour V. HIV DNA and dementia in treatment-naïve HIV-1-infected individuals in Bangkok, Thailand. Int J Med Sci. 2006 Dec 06; 4(1):13-8. View on Pubmed
  172. Valcour VG, Sacktor NC, Paul RH, Watters MR, Selnes OA, Shiramizu BT, Williams AE, Shikuma CM. Insulin resistance is associated with cognition among HIV-1-infected patients: the Hawaii Aging With HIV cohort. . 2006 Dec 01; 43(4):405-10. View on Pubmed
  173. Valcour V, Yee P, Williams AE, Shiramizu B, Watters M, Selnes O, Paul R, Shikuma C, Sacktor N. Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infection--The Hawaii Aging with HIV Cohort. J Neurovirol. 2006 Oct; 12(5):387-91. View on Pubmed
  174. Valcour V, Paul R. HIV infection and dementia in older adults. Clin Infect Dis. 2006 May 15; 42(10):1449-54. View on Pubmed
  175. Tokuhara KG, Valcour VG, Masaki KH, Blanchette PL. Utility of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for dementia in a Japanese-American population. Hawaii Med J. 2006 Mar; 65(3):72-5. View on Pubmed
  176. Kalayjian RC, Spritzler J, Pu M, Landay A, Pollard RB, Stocker V, Harthi LA, Gross BH, Francis IR, Fiscus SA, Tebas P, Bosch RJ, Valcour V, Lederman MM, Adult AIDS Clinical Trials Group 5015 and 5113 Study Teams . Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease. J Infect Dis. 2005 Nov 01; 192(9):1577-87. View on Pubmed
  177. Killebrew DA, Troelstrup D, Valcour V, Williams A, Aguon J, Sapalo D, Shikuma C, Ratto-Kim S, Shiramizu B. Discordant plasma and cerebral spinal fluid cytokines/chemokines in relation to HIV-1-associated dementia. Cell Mol Biol (Noisy-le-grand). 2005 Sep 02; 51 Suppl:OL745-54. View on Pubmed
  178. Shikuma CM, Valcour VG, Ratto-Kim S, Williams AE, Souza S, Gerschenson M, Day L, Kim JH, Shiramizu B. HIV-associated wasting in the era of highly active antiretroviral therapy: a syndrome of residual HIV infection in monocytes and macrophages? Clin Infect Dis. 2005 Jun 15; 40(12):1846-8. View on Pubmed
  179. Shiramizu B, Gartner S, Williams A, Shikuma C, Ratto-Kim S, Watters M, Aguon J, Valcour V. Circulating proviral HIV DNA and HIV-associated dementia. AIDS. 2005 Jan 03; 19(1):45-52. View on Pubmed
  180. Valcour VG, Shikuma CM, Shiramizu BT, Williams AE, Watters MR, Poff PW, Grove JS, Selnes OA, Sacktor NC. Diabetes, insulin resistance, and dementia among HIV-1-infected patients. . 2005 Jan 01; 38(1):31-6. View on Pubmed
  181. Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes OA, Grove J, Liu Y, Abdul-Majid KB, Gartner S, Sacktor N. Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii Aging with HIV Cohort. J Neuroimmunol. 2004 Dec; 157(1-2):197-202. View on Pubmed
  182. Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes O, Holck P, Grove J, Sacktor N. Higher frequency of dementia in older HIV-1 individuals: the Hawaii Aging with HIV-1 Cohort. Neurology. 2004 Sep 14; 63(5):822-7. View on Pubmed
  183. Valcour V, Shiramizu B. HIV-associated dementia, mitochondrial dysfunction, and oxidative stress. Mitochondrion. 2004 Jul; 4(2-3):119-29. View on Pubmed
  184. Watters MR, Poff PW, Shiramizu BT, Holck PS, Fast KM, Shikuma CM, Valcour VG. Symptomatic distal sensory polyneuropathy in HIV after age 50. Neurology. 2004 Apr 27; 62(8):1378-83. View on Pubmed
  185. Shiramizu B, Gartner S, Cho M, Liu Y, Pyron N, Valcour V, Shikuma C. Assessment of HIV-1 DNA copies per cell by real-time polymerase chain reaction. Front Biosci. 2004 Jan 01; 9:255-61. View on Pubmed
  186. Valcour VG, Shikuma CM, Watters MR, Sacktor NC. Cognitive impairment in older HIV-1-seropositive individuals: prevalence and potential mechanisms. AIDS. 2004 Jan 01; 18 Suppl 1:S79-86. View on Pubmed
  187. Fernandes R, Valcour V, Flynn B, Masaki K, Blanchette P. Tetanus immunity in long-term care facilities. J Am Geriatr Soc. 2003 Aug; 51(8):1116-9. View on Pubmed
  188. Valcour VG, Masaki KH, Blanchette PL. Self-reported driving, cognitive status, and physician awareness of cognitive impairment. J Am Geriatr Soc. 2002 Jul; 50(7):1265-7. View on Pubmed
  189. Valcour VG, Masaki KH, Blanchette PL. The phrase: "no ifs, ands, or buts" and cognitive testing. Lessons from an Asian-American community. Hawaii Med J. 2002 Apr; 61(4):72-4. View on Pubmed
  190. Valcour VG, Masaki KH, Curb JD, Blanchette PL. The detection of dementia in the primary care setting. Arch Intern Med. 2000 Oct 23; 160(19):2964-8. View on Pubmed
  191. Cooper TA, Valcour VG, Gibbons RB, O'Brien-Falls K. Spontaneous ecchymoses due to paroxetine administration. Am J Med. 1998 Feb; 104(2):197-8. View on Pubmed