Victor Valcour, MD

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(415) 476-3746

675 Nelson Rising Lane
San Francisco, CA 94158

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  • Professor, School of Medicine
  • Member, CFAR Scientific Council

Biography

OVERVIEW

Dr. Valcour is a Professor of Medicine with a shared appointment in the Division of Geriatric Medicine and the Department of Neurology. His work crosses disciplines to research and care for cognitive disorders in aging populations and to understand brain injury in the setting of HIV among all ages, including funded pediatric HIV studies. His clinical work involves consultations for patients with cognitive disorders at the Memory and Aging Center/UCSF.

While much of Dr. Valcour's research is completed at UCSF, he has a large internationa porfolio with many opportunities for junior investigators. Within Southeast Asia, he is Deputy Director of SEARCH/Thailand operating research in acute HIV (within days of infection), pediatric HIV, and markers of dementia in chronic HIV. In Africa, he has partnered with the US Military HIV Research Program to survey cognitive disorders among HIV-infected individuals in Nigeria, Uganda, Kenya, and Tanzania.

Dr. Valcour is broadly involved in mentoring individuals at all levels of training who are interested in clinical research related to cognitive disorders, particularly in association with HIV infection. He has extensive global health experience.

RESEARCH

Dr. Valcour’s research interests have two major emphases. He is currently developing a research program that aims to understand optimal care strategies for elders who develop dementia. Nested within the UCSF Memory and Aging Center, the long-term goal of this program is to provide model care for elders with cognitive disorders.

Dr. Valcour is internationally recognized for research in cognitive disorders related to HIV. He currently operates 3 NIH R01 series grants within 3 novel cohorts: (1) a chronic HIV infected cohort followed since first initiation of cART; (2) an acute HIV cohort of individuals infected for less than one month at enrollment; (3) and a pediatric cohort in Thailand and Cambodia. He is the Deputy Director of SEARCH/Thailand (www.SEARCHThailand.org). He also operates the UCSF HIV Over 60 Cohort focused on understanding cognitive disorders in the older HIV population living in the San Francisco Bay area. New research will survey of cognitive disorders in HIV for individuals living in Uganda, Kenya, Tanzania and Nigeria.

ACADEMIC FOCUS

Dr. Valcour is actively engaged in mentoring individuals wishing to become independent clinical researchers. His research portfolio provides a broad array of local and international projects that can serve as resources for mentored projects. Dr. Valcour serves as an Executive Committee member of the AIDS Research Institute (ARI)

Awards

Displaying 1 - 175 of 175

  1. Bobrow K, Xia F, Hoang T, Valcour V, Yaffe K. HIV and risk of dementia in older veterans. AIDS. 2020 Jul 23. View on Pubmed
  2. Sharma V, Bryant C, Montero M, Creegan M, Slike B, Krebs SJ, Ratto-Kim S, Valcour V, Sithinamsuwan P, Chalermchai T, Eller MA, Bolton DL. Monocyte and CD4+ T-cell antiviral and innate responses associated with HIV-1 inflammation and cognitive impairment. AIDS. 2020 Jul 15; 34(9):1289-1301. View on Pubmed
  3. Premeaux TA, Javandel S, Hosaka KRJ, Greene M, Therrien N, Allen IE, Corley MJ, Valcour VG, Ndhlovu LC. Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. Front Immunol. 2020; 11:1321. View on Pubmed
  4. Kamkwalala AR, Wang X, Maki PM, Williams DW, Valcour VG, Damron A, Tien PC, Weber KM, Cohen MH, Sundermann EE, Meyer VJ, Little DM, Xu Y, Rubin LH. Brief Report: Higher Peripheral Monocyte Activation Markers Are Associated With Smaller Frontal and Temporal Cortical Volumes in Women With HIV. J Acquir Immune Defic Syndr. 2020 May 01; 84(1):54-59. View on Pubmed
  5. RifeMagalis B, Strickland SL, Shank SD, Autissier P, Schuetz A, Sithinamsuwan P, Lerdlum S, Fletcher JLK, de Souza M, Ananworanich J, Valcour V, Williams KC, Kosakovsky Pond SL, RattoKim S, Salemi M. Phyloanatomic characterization of the distinct T cell and monocyte contributions to the peripheral blood HIV population within the host. Virus Evol. 2020 Jan; 6(1):veaa005. View on Pubmed
  6. Rubin LH, Xu Y, Norris PJ, Wang X, Dastgheyb R, Fitzgerald KC, Keating SM, Kaplan RC, Maki PM, Anastos K, Springer G, Benning L, Kassaye S, Gustafson DR, Valcour VG, Williams DW. Early Inflammatory Signatures Predict Subsequent Cognition in Long-Term Virally Suppressed Women With HIV. Front Integr Neurosci. 2020; 14:20. View on Pubmed
  7. Sharma V, Bryant C, Montero M, Creegan M, Slike B, Krebs SJ, Ratto-Kim S, Valcour V, Sithinamsuwan P, Chalermchai T, Eller MA, Bolton DL. Monocyte and CD4+ T cell antiviral and innate responses associated with HIV-1 inflammation and cognitive impairment. AIDS. 2020 Apr 13. View on Pubmed
  8. Paul RH, Cho KS, Belden AC, Mellins CA, Malee KM, Robbins RN, Salminen LE, Kerr SJ, Adhikari B, Garcia-Egan PM, Sophonphan J, Aurpibul L, Thongpibul K, Kosalaraksa P, Kanjanavanit S, Ngampiyaskul C, Wongsawat J, Vonthanak S, Suwanlerk T, Valcour VG, Preston-Campbell RN, Bolzenious JD, Robb ML, Ananworanich J, Puthanakit T. Machine-learning classification of neurocognitive performance in children with perinatal HIV initiating de novo antiretroviral therapy. AIDS. 2020 04 01; 34(5):737-748. View on Pubmed
  9. Leyre L, Kroon E, Vandergeeten C, Sacdalan C, Colby DJ, Buranapraditkun S, Schuetz A, Chomchey N, de Souza M, Bakeman W, Fromentin R, Pinyakorn S, Akapirat S, Trichavaroj R, Chottanapund S, Manasnayakorn S, Rerknimitr R, Wattanaboonyoungcharoen P, Kim JH, Tovanabutra S, Schacker TW, O'Connell R, Valcour VG, Phanuphak P, Robb ML, Michael N, Trautmann L, Phanuphak N, Ananworanich J, Chomont N. Abundant HIV-infected cells in blood and tissues are rapidly cleared upon ART initiation during acute HIV infection. Sci Transl Med. 2020 Mar 04; 12(533). View on Pubmed
  10. Kallianpur KJ, Jahanshad N, Sailasuta N, Benjapornpong K, Chan P, Pothisri M, Dumrongpisutikul N, Laws E, Ndhlovu LC, Clifford KM, Paul R, Jagodzinski L, Krebs S, Ananworanich J, Spudich S, Valcour V. Regional brain volumetric changes despite 2 years of treatment initiated during acute HIV infection. AIDS. 2020 03 01; 34(3):415-426. View on Pubmed
  11. Milanini B, Allen I, Paul R, Bahemana E, Kiweewa F, Nambuya A, Maswai J, Langat R, Owuoth J, Martin S, Possin K, Esber A, Polyak C, Ake JA, Valcour V. Frequency and Predictors of HIV-Related Cognitive Impairment in East Africa: The Africa Cohort Study (AFRICOS). J Acquir Immune Defic Syndr. 2020 02 01; 83(2):157-164. View on Pubmed
  12. Chang K, Premeaux TA, Cobigo Y, Milanini B, Hellmuth J, Rubin LH, Javandel S, Allen I, Ndhlovu LC, Paul R, Valcour V. Plasma inflammatory biomarkers link to diffusion tensor imaging metrics in virally suppressed HIV-infected individuals. AIDS. 2020 02 01; 34(2):203-213. View on Pubmed
  13. Philippi CL, Reyna L, Nedderman L, Chan P, Samboju V, Chang K, Phanuphak N, Ratnaratorn N, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Robb ML, Ananworanich J, Spudich S, Valcour V, Paul R. Resting-state neural signatures of depressive symptoms in acute HIV. J Neurovirol. 2020 04; 26(2):226-240. View on Pubmed
  14. Chan P, Goh O, Kroon E, Colby D, Sacdalan C, Pinyakorn S, Prueksakaew P, Reiss P, Ananworanich J, Valcour V, Spudich S, Paul R. Neuropsychiatric outcomes before and after switching to dolutegravir-based therapy in an acute HIV cohort. AIDS Res Ther. 2020 01 07; 17(1):1. View on Pubmed
  15. Halpin SN, Ge L, Mehta CC, Gustafson D, Robertson KR, Rubin LH, Sharma A, Vance D, Valcour V, Waldrop-Valverde D, Ofotokun I. Psychosocial Resources and Emotions in Women Living With HIV Who Have Cognitive Impairment: Applying the Socio-Emotional Adaptation Theory. Res Theory Nurs Pract. 2020 Jan 01; 34(1):49-64. View on Pubmed
  16. Massanella M, Bakeman W, Sithinamsuwan P, Fletcher JLK, Chomchey N, Tipsuk S, Chalermchai T, Routy JP, Ananworanich J, Valcour VG, Chomont N. Infrequent HIV Infection of Circulating Monocytes during Antiretroviral Therapy. J Virol. 2019 12 12; 94(1). View on Pubmed
  17. Hellmuth J, Slike BM, Sacdalan C, Best J, Kroon E, Phanuphak N, Fletcher JLK, Prueksakaew P, Jagodzinski LL, Valcour V, Robb M, Ananworanich J, Allen IE, Krebs SJ, Spudich S. Very Early Initiation of Antiretroviral Therapy During Acute HIV Infection Is Associated With Normalized Levels of Immune Activation Markers in Cerebrospinal Fluid but Not in Plasma. J Infect Dis. 2019 11 06; 220(12):1885-1891. View on Pubmed
  18. Chan P, Dumrongpisutikul N, Subra C, Colby DJ, Kroon E, Fletcher J, Sacdalan C, Phanuphak N, Valcour V, Ananworanich J, Trautmann L, Spudich S. Neurosyphilis During Acute HIV Infection: A CNS Immunologic and Virologic Characterization. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):e34-e37. View on Pubmed
  19. Muñoz-Nevárez LA, Imp BM, Eller MA, Kiweewa F, Maswai J, Polyak C, Olwenyi OA, Allen IE, Rono E, Milanini B, Kibuuka H, Ake JA, Eller LA, Valcour VG. Monocyte activation, HIV, and cognitive performance in East Africa. J Neurovirol. 2020 02; 26(1):52-59. View on Pubmed
  20. Tovanabutra S, Sirijatuphat R, Pham PT, Bonar L, Harbolick EA, Bose M, Song H, Chang D, Oropeza C, O'Sullivan AM, Balinang J, Kroon E, Colby DJ, Sacdalan C, Hellmuth J, Chan P, Prueksakaew P, Pinyakorn S, Jagodzinski LL, Sutthichom D, Pattamaswin S, de Souza M, Gramzinski RA, Kim JH, Michael NL, Robb ML, Phanuphak N, Ananworanich J, Valcour V, Kijak GH, Sanders-Buell E, Spudich S. Deep Sequencing Reveals Central Nervous System Compartmentalization in Multiple Transmitted/Founder Virus Acute HIV-1 Infection. Cells. 2019 08 15; 8(8). View on Pubmed
  21. Ake JA, Polyak CS, Crowell TA, Kiweewa F, Semwogerere M, Maganga L, Bahemana E, Maswai J, Langat R, Owuoth J, Otieno S, Keshinro B, Esber AL, Liu M, Eller LA, Ganesan K, Parikh AP, Hamm TE, Robb ML, Hickey PW, Valcour VG, Michael NL. Noninfectious Comorbidity in the African Cohort Study. Clin Infect Dis. 2019 08 01; 69(4):639-647. View on Pubmed
  22. Milanini B, Samboju V, Cobigo Y, Paul R, Javandel S, Hellmuth J, Allen I, Miller B, Valcour V. Longitudinal brain atrophy patterns and neuropsychological performance in older adults with HIV-associated neurocognitive disorder compared with early Alzheimer's disease. Neurobiol Aging. 2019 10; 82:69-76. View on Pubmed
  23. Rubin LH, Springer G, Martin EM, Seaberg EC, Sacktor NC, Levine A, Valcour VG, Young MA, Becker JT, Maki PM. Elevated Depressive Symptoms Are a Stronger Predictor of Executive Dysfunction in HIV-Infected Women Than in Men. J Acquir Immune Defic Syndr. 2019 07 01; 81(3):274-283. View on Pubmed
  24. Hosaka KRJ, Greene M, Premeaux TA, Javandel S, Allen IE, Ndhlovu LC, Valcour V. Geriatric Syndromes in Older Adults Living with HIV and Cognitive Impairment. J Am Geriatr Soc. 2019 09; 67(9):1913-1916. View on Pubmed
  25. Malee KM, Kerr S, Paul R, Puthanakit T, Thongpibul K, Kosalaraksa P, Ounchanum P, Kanjanavanit S, Aurpibul L, Ngampiyaskul C, Luesomboon W, Wongsawat J, Vonthanak S, Ly PS, Chettra K, Suwanlerk T, Sophonphan J, Valcour V, Ananworanich J, Mellins CA. Emotional and behavioral resilience among children with perinatally acquired HIV in Thailand and Cambodia. AIDS. 2019 06 01; 33 Suppl 1:S17-S27. View on Pubmed
  26. Meffert SM, Neylan TC, McCulloch CE, Maganga L, Adamu Y, Kiweewa F, Maswai J, Owuoth J, Polyak CS, Ake JA, Valcour VG. East African HIV care: depression and HIV outcomes. Glob Ment Health (Camb). 2019; 6:e9. View on Pubmed
  27. Wade BSC, Valcour VG, Puthanakit T, Saremi A, Gutman BA, Nir TM, Watson C, Aurpibul L, Kosalaraksa P, Ounchanum P, Kerr S, Dumrongpisutikul N, Visrutaratna P, Srinakarin J, Pothisri M, Narr KL, Thompson PM, Ananworanich J, Paul RH, Jahanshad N. Mapping abnormal subcortical neurodevelopment in a cohort of Thai children with HIV. Neuroimage Clin. 2019; 23:101810. View on Pubmed
  28. Premeaux TA, D'Antoni ML, Abdel-Mohsen M, Pillai SK, Kallianpur KJ, Nakamoto BK, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Gisslén M, Price RW, Valcour V, Ndhlovu LC. Elevated cerebrospinal fluid Galectin-9 is associated with central nervous system immune activation and poor cognitive performance in older HIV-infected individuals. J Neurovirol. 2019 04; 25(2):150-161. View on Pubmed
  29. Narvid J, McCoy D, Dupont SM, Callen A, Tosun D, Hellmuth J, Valcour V. Abnormal Cerebral Perfusion Profile in Older Adults with HIV-Associated Neurocognitive Disorder: Discriminative Power of Arterial Spin-Labeling. AJNR Am J Neuroradiol. 2018 12; 39(12):2211-2217. View on Pubmed
  30. Milanini B, Paul R, Bahemana E, Adamu Y, Kiweewa F, Langat R, Owuoth J, Allen E, Polyak C, Ake J, Valcour V. Limitations of the International HIV Dementia Scale in the current era. AIDS. 2018 11 13; 32(17):2477-2483. View on Pubmed
  31. Kim EJ, Brown JA, Deng J, Hwang JL, Spina S, Miller ZA, DeMay MG, Valcour V, Karydas A, Ramos EM, Coppola G, Miller BL, Rosen HJ, Seeley WW, Grinberg LT. Mixed TDP-43 proteinopathy and tauopathy in frontotemporal lobar degeneration: nine case series. J Neurol. 2018 Dec; 265(12):2960-2971. View on Pubmed
  32. Hellmuth J, Milanini B, Masliah E, Tartaglia MC, Dunlop MB, Moore DJ, Javandel S, DeVaughn S, Valcour V. A neuropathologic diagnosis of Alzheimer's disease in an older adult with HIV-associated neurocognitive disorder. Neurocase. 2018 08; 24(4):213-219. View on Pubmed
  33. D'Antoni ML, Byron MM, Chan P, Sailasuta N, Sacdalan C, Sithinamsuwan P, Tipsuk S, Pinyakorn S, Kroon E, Slike BM, Krebs SJ, Khadka VS, Chalermchai T, Kallianpur KJ, Robb M, Spudich S, Valcour V, Ananworanich J, Ndhlovu LC. Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities. J Infect Dis. 2018 09 22; 218(9):1453-1463. View on Pubmed
  34. Maki PM, Rubin LH, Springer G, Seaberg EC, Sacktor N, Miller EN, Valcour V, Young MA, Becker JT, Martin EM. Differences in Cognitive Function Between Women and Men With HIV. J Acquir Immune Defic Syndr. 2018 09 01; 79(1):101-107. View on Pubmed
  35. Chan P, Patel P, Hellmuth J, Colby DJ, Kroon E, Sacdalan C, Pinyakorn S, Jagodzinski L, Krebs S, Ananworanich J, Valcour V, Spudich S. Distribution of Human Immunodeficiency Virus (HIV) Ribonucleic Acid in Cerebrospinal Fluid and Blood Is Linked to CD4/CD8 Ratio During Acute HIV. J Infect Dis. 2018 08 14; 218(6):937-945. View on Pubmed
  36. Samboju V, Philippi CL, Chan P, Cobigo Y, Fletcher JLK, Robb M, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Paul R, Ananworanich J, Spudich S, Valcour V. Structural and functional brain imaging in acute HIV. Neuroimage Clin. 2018; 20:327-335. View on Pubmed
  37. Huck DM, Hanna DB, Rubin LH, Maki P, Valcour V, Springer G, Xue X, Lazar J, Hodis HN, Anastos K, Kaplan RC, Kizer JR. Carotid Artery Stiffness and Cognitive Decline Among Women With or at Risk for HIV Infection. J Acquir Immune Defic Syndr. 2018 07 01; 78(3):338-347. View on Pubmed
  38. Paul R, Prasitsuebsai W, Jahanshad N, Puthanakit T, Thompson P, Aurpibul L, Hansudewechakul R, Kosalaraksa P, Kanjanavanit S, Ngampiyaskul C, Luesomboon W, Lerdlum S, Pothisri M, Visrutaratna P, Valcour V, Nir TM, Saremi A, Kerr S, Ananworanich J. Structural Neuroimaging and Neuropsychologic Signatures in Children With Vertically Acquired HIV. Pediatr Infect Dis J. 2018 07; 37(7):662-668. View on Pubmed
  39. Ratto-Kim S, Schuetz A, Sithinamsuwan P, Barber J, Hutchings N, Lerdlum S, Fletcher JLK, Phuang-Ngern Y, Chuenarom W, Tipsuk S, Pothisri M, Jadwattanakul T, Jirajariyavej S, Sajjaweerawan C, Akapirat S, Chalermchai T, Suttichom D, Kaewboon B, Prueksakaew P, Karnsomlap P, Clifford D, Paul RH, de Souza MS, Kim JH, Ananworanich J, Valcour V. Characterization of Cellular Immune Responses in Thai Individuals With and Without HIV-Associated Neurocognitive Disorders. AIDS Res Hum Retroviruses. 2018 08; 34(8):685-689. View on Pubmed
  40. Hsu DC, Sunyakumthorn P, Wegner M, Schuetz A, Silsorn D, Estes JD, Deleage C, Tomusange K, Lakhashe SK, Ruprecht RM, Lombardini E, Im-Erbsin R, Kuncharin Y, Phuang-Ngern Y, Inthawong D, Chuenarom W, Burke R, Robb ML, Ndhlovu LC, Ananworanich J, Valcour V, O'Connell RJ, Spudich S, Michael NL, Vasan S. Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques. J Virol. 2018 06 01; 92(11). View on Pubmed
  41. Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, Valcour VG, Spudich S, Michael NL, Robb ML, Phanuphak N, Ananworanich J. Acute Retroviral Syndrome Is Associated With High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments. Clin Infect Dis. 2018 05 02; 66(10):1540-1549. View on Pubmed
  42. Paul R, Apornpong T, Prasitsuebsai W, Puthanakit T, Saphonn V, Aurpibul L, Kosalaraksa P, Kanjanavanit S, Luesomboon W, Ngampiyaskul C, Suwanlerk T, Chettra K, Shearer WT, Valcour V, Ananworanich J, Kerr S. Cognition, Emotional Health, and Immunological Markers in Children With Long-Term Nonprogressive HIV. J Acquir Immune Defic Syndr. 2018 04 01; 77(4):417-426. View on Pubmed
  43. Do TC, Kerr SJ, Avihingsanon A, Suksawek S, Klungkang S, Channgam T, Odermatt CC, Maek-A-Nantawat W, Ruxtungtham K, Ananworanich J, Valcour V, Reiss P, Wit FW. HIV-associated cognitive performance and psychomotor impairment in a Thai cohort on long-term cART. J Virus Erad. 2018 Jan 01; 4(1):41-47. View on Pubmed
  44. Chan P, Hellmuth J, Colby D, Kroon E, Sacdalan C, Fletcher J, Patel P, Pinyakorn S, Valcour V, Ananworanich J, Spudich S. Safety of lumbar puncture procedure in an international research setting during acute HIV infection. J Virus Erad. 2018 Jan 01; 4(1):16-20. View on Pubmed
  45. Hellmuth J, Colby D, Valcour V, Suttichom D, Spudich S, Ananworanich J, Prueksakaew P, Sailasuta N, Allen I, Jagodzinski LL, Slike B, Ochi D, Paul R. Depression and Anxiety are Common in Acute HIV Infection and Associate with Plasma Immune Activation. AIDS Behav. 2017 Nov; 21(11):3238-3246. View on Pubmed
  46. Clifford KM, Samboju V, Cobigo Y, Milanini B, Marx GA, Hellmuth JM, Rosen HJ, Kramer JH, Allen IE, Valcour VG. Progressive Brain Atrophy Despite Persistent Viral Suppression in HIV Patients Older Than 60 Years. J Acquir Immune Defic Syndr. 2017 11 01; 76(3):289-297. View on Pubmed
  47. Rubin LH, Benning L, Keating SM, Norris PJ, Burke-Miller J, Savarese A, Kumanan KN, Awadalla S, Springer G, Anastos K, Young M, Milam J, Valcour VG, Weber KM, Maki PM. Variability in C-reactive protein is associated with cognitive impairment in women living with and without HIV: a longitudinal study. J Neurovirol. 2018 02; 24(1):41-51. View on Pubmed
  48. Rubin LH, Maki PM, Springer G, Benning L, Anastos K, Gustafson D, Villacres MC, Jiang X, Adimora AA, Waldrop-Valverde D, Vance DE, Bolivar H, Alden C, Martin EM, Valcour VG. Cognitive trajectories over 4 years among HIV-infected women with optimal viral suppression. Neurology. 2017 Oct 10; 89(15):1594-1603. View on Pubmed
  49. Rubin LH, Cook JA, Springer G, Weber KM, Cohen MH, Martin EM, Valcour VG, Benning L, Alden C, Milam J, Anastos K, Young MA, Gustafson DR, Sundermann EE, Maki PM. Perceived and post-traumatic stress are associated with decreased learning, memory, and fluency in HIV-infected women. AIDS. 2017 11; 31(17):2393-1401. View on Pubmed
  50. Milanini B, Valcour V. Differentiating HIV-Associated Neurocognitive Disorders From Alzheimer's Disease: an Emerging Issue in Geriatric NeuroHIV. Curr HIV/AIDS Rep. 2017 08; 14(4):123-132. View on Pubmed
  51. Kessing CF, Spudich S, Valcour V, Cartwright P, Chalermchai T, Fletcher JL, Takata H, Nichols C, Josey BJ, Slike B, Krebs SJ, Sailsuta N, Lerdlum S, Jagodzinski L, Tipsuk S, Suttichom D, Rattanamanee S, Zetterberg H, Hellmuth J, Phanuphak N, Robb ML, Michael NL, Ananworanich J, Trautmann L. High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection. J Acquir Immune Defic Syndr. 2017 05 01; 75(1):108-117. View on Pubmed
  52. Agsalda-Garcia MA, Sithinamsuwan P, Valcour VG, Chalermchai T, Tipsuk S, Kuroda J, Nakamura C, Ananworanich J, Zhang G, Schuetz A, Slike BM, Shiramizu B. Brief Report: CD14+ Enriched Peripheral Cells Secrete Cytokines Unique to HIV-Associated Neurocognitive Disorders. J Acquir Immune Defic Syndr. 2017 04 01; 74(4):454-458. View on Pubmed
  53. Vance DE, Rubin LH, Valcour V, Waldrop-Valverde D, Maki PM. Erratum to: Aging and Neurocognitive Functioning in HIV-Infected Women: a Review of the Literature Involving the Women's Interagency HIV Study. Curr HIV/AIDS Rep. 2017 02; 14(1):38. View on Pubmed
  54. Milanini B, Catella S, Perkovich B, Esmaeili-Firidouni P, Wendelken L, Paul R, Greene M, Ketelle R, Valcour V. Psychiatric symptom burden in older people living with HIV with and without cognitive impairment: the UCSF HIV over 60 cohort study. AIDS Care. 2017 09; 29(9):1178-1185. View on Pubmed
  55. Watson C, Busovaca E, Foley JM, Allen IE, Schwarz CG, Jahanshad N, Nir TM, Esmaeili-Firidouni P, Milanini B, Rosen H, Carmichael OT, Thompson PM, Valcour VG. White matter hyperintensities correlate to cognition and fiber tract integrity in older adults with HIV. J Neurovirol. 2017 06; 23(3):422-429. View on Pubmed
  56. Peluso MJ, Valcour V, Phanuphak N, Ananworanich J, Fletcher JL, Chalermchai T, Krebs SJ, Robb ML, Hellmuth J, Gisslén M, Zetterberg H, Spudich S. Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection. AIDS. 2017 01 14; 31(2):247-252. View on Pubmed
  57. Vance DE, Rubin LH, Valcour V, Waldrop-Valverde D, Maki PM. Aging and Neurocognitive Functioning in HIV-Infected Women: a Review of the Literature Involving the Women's Interagency HIV Study. Curr HIV/AIDS Rep. 2016 12; 13(6):399-411. View on Pubmed
  58. Wendelken LA, Jahanshad N, Rosen HJ, Busovaca E, Allen I, Coppola G, Adams C, Rankin KP, Milanini B, Clifford K, Wojta K, Nir TM, Gutman BA, Thompson PM, Valcour V. ApoE e4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60. J Acquir Immune Defic Syndr. 2016 Dec 01; 73(4):426-432. View on Pubmed
  59. Kamtchum-Tatuene J, Wan Sulaiman WA, Lekoubou A, Hellmuth J, Valcour V, Spudich S. Neurologic signs and symptoms frequently manifest in acute HIV infection. Neurology. 2016 11 29; 87(22):2386. View on Pubmed
  60. Imp BM, Rubin LH, Tien PC, Plankey MW, Golub ET, French AL, Valcour VG. Monocyte Activation Is Associated With Worse Cognitive Performance in HIV-Infected Women With Virologic Suppression. J Infect Dis. 2017 Jan 01; 215(1):114-121. View on Pubmed
  61. Sereti I, Krebs SJ, Phanuphak N, Fletcher JL, Slike B, Pinyakorn S, O'Connell RJ, Rupert A, Chomont N, Valcour V, Kim JH, Robb ML, Michael NL, Douek DC, Ananworanich J, Utay NS. Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection. Clin Infect Dis. 2017 Jan 15; 64(2):124-131. View on Pubmed
  62. Corley MJ, Dye C, D'Antoni ML, Byron MM, Yo KL, Lum-Jones A, Nakamoto B, Valcour V, SahBandar I, Shikuma CM, Ndhlovu LC, Maunakea AK. Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment. Sci Rep. 2016 09 15; 6:33310. View on Pubmed
  63. Zhang Y, Kwon D, Esmaeili-Firidouni P, Pfefferbaum A, Sullivan EV, Javitz H, Valcour V, Pohl KM. Extracting patterns of morphometry distinguishing HIV associated neurodegeneration from mild cognitive impairment via group cardinality constrained classification. Hum Brain Mapp. 2016 12; 37(12):4523-4538. View on Pubmed
  64. Chan P, Hellmuth J, Spudich S, Valcour V. Cognitive Impairment and Persistent CNS Injury in Treated HIV. Curr HIV/AIDS Rep. 2016 08; 13(4):209-17. View on Pubmed
  65. Muir R, Metcalf T, Tardif V, Takata H, Phanuphak N, Kroon E, Colby DJ, Trichavaroj R, Valcour V, Robb ML, Michael NL, Ananworanich J, Trautmann L, Haddad EK. Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection. PLoS Pathog. 2016 07; 12(7):e1005777. View on Pubmed
  66. Valcour VG, Rubin LH, Obasi MU, Maki PM, Peters MG, Levin S, Crystal HA, Young MA, Mack WJ, Cohen MH, Pierce CB, Adimora AA, Tien PC. Liver Fibrosis Linked to Cognitive Performance in HIV and Hepatitis C. J Acquir Immune Defic Syndr. 2016 07 01; 72(3):266-73. View on Pubmed
  67. Krebs SJ, Slike BM, Sithinamsuwan P, Allen IE, Chalermchai T, Tipsuk S, Phanuphak N, Jagodzinski L, Kim JH, Ananworanich J, Marovich MA, Valcour VG. Sex differences in soluble markers vary before and after the initiation of antiretroviral therapy in chronically HIV-infected individuals. AIDS. 2016 06 19; 30(10):1533-42. View on Pubmed
  68. Hellmuth J, Fletcher JL, Valcour V, Kroon E, Ananworanich J, Intasan J, Lerdlum S, Narvid J, Pothisri M, Allen I, Krebs SJ, Slike B, Prueksakaew P, Jagodzinski LL, Puttamaswin S, Phanuphak N, Spudich S. Neurologic signs and symptoms frequently manifest in acute HIV infection. Neurology. 2016 07 12; 87(2):148-54. View on Pubmed
  69. Sailasuta N, Ananworanich J, Lerdlum S, Sithinamsuwan P, Fletcher JL, Tipsuk S, Pothisri M, Jadwattanakul T, Jirajariyavej S, Chalermchai T, Catella S, Busovaca E, Desai A, Paul R, Valcour V. Neuronal-Glia Markers by Magnetic Resonance Spectroscopy in HIV Before and After Combination Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2016 Jan 01; 71(1):24-30. View on Pubmed
  70. Ananworanich J, Sacdalan CP, Pinyakorn S, Chomont N, de Souza M, Luekasemsuk T, Schuetz A, Krebs SJ, Dewar R, Jagodzinski L, Ubolyam S, Trichavaroj R, Tovanabutra S, Spudich S, Valcour V, Sereti I, Michael N, Robb M, Phanuphak P, Kim JH, Phanuphak N. Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection. J Virus Erad. 2016; 2:43-48. View on Pubmed
  71. Kore I, Ananworanich J, Valcour V, Fletcher JL, Chalermchai T, Paul R, Reynolds J, Tipsuk S, Ubolyam S, Rattanamanee S, Jagodzinski L, Kim J, Spudich S. Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2015 Dec 01; 70(4):393-9. View on Pubmed
  72. Valcour VG, Spudich SS, Sailasuta N, Phanuphak N, Lerdlum S, Fletcher JL, Kroon ED, Jagodzinski LL, Allen IE, Adams CL, Prueksakaew P, Slike BM, Hellmuth JM, Kim JH, Ananworanich J. Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV. PLoS One. 2015; 10(11):e0142600. View on Pubmed
  73. Wade BS, Valcour VG, Wendelken-Riegelhaupt L, Esmaeili-Firidouni P, Joshi SH, Gutman BA, Thompson PM. Mapping abnormal subcortical brain morphometry in an elderly HIV+ cohort. Neuroimage Clin. 2015; 9:564-73. View on Pubmed
  74. Rubin LH, Pyra M, Cook JA, Weber KM, Cohen MH, Martin E, Valcour V, Milam J, Anastos K, Young MA, Alden C, Gustafson DR, Maki PM. Post-traumatic stress is associated with verbal learning, memory, and psychomotor speed in HIV-infected and HIV-uninfected women. J Neurovirol. 2016 Apr; 22(2):159-69. View on Pubmed
  75. Ndhlovu LC, D'Antoni ML, Ananworanich J, Byron MM, Chalermchai T, Sithinamsuwan P, Tipsuk S, Ho E, Slike BM, Schuetz A, Zhang G, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Valcour V. Loss of CCR2 expressing non-classical monocytes are associated with cognitive impairment in antiretroviral therapy-naïve HIV-infected Thais. J Neuroimmunol. 2015 Nov 15; 288:25-33. View on Pubmed
  76. Jahanshad N, Couture MC, Prasitsuebsai W, Nir TM, Aurpibul L, Thompson PM, Pruksakaew K, Lerdlum S, Visrutaratna P, Catella S, Desai A, Kerr SJ, Puthanakit T, Paul R, Ananworanich J, Valcour VG. Brain Imaging and Neurodevelopment in HIV-uninfected Thai Children Born to HIV-infected Mothers. Pediatr Infect Dis J. 2015 Sep; 34(9):e211-6. View on Pubmed
  77. Guha A, Wang L, Tanenbaum A, Esmaeili-Firidouni P, Wendelken LA, Busovaca E, Clifford K, Desai A, Ances BM, Valcour V. Intrinsic network connectivity abnormalities in HIV-infected individuals over age 60. J Neurovirol. 2016 Feb; 22(1):80-7. View on Pubmed
  78. Greene M, Covinsky KE, Valcour V, Miao Y, Madamba J, Lampiris H, Cenzer IS, Martin J, Deeks SG. Geriatric Syndromes in Older HIV-Infected Adults. J Acquir Immune Defic Syndr. 2015 Jun 01; 69(2):161-7. View on Pubmed
  79. Peluso MJ, Valcour V, Ananworanich J, Sithinamsuwan P, Chalermchai T, Fletcher JL, Lerdlum S, Chomchey N, Slike B, Sailasuta N, Gisslén M, Zetterberg H, Spudich S. Absence of Cerebrospinal Fluid Signs of Neuronal Injury Before and After Immediate Antiretroviral Therapy in Acute HIV Infection. J Infect Dis. 2015 Dec 01; 212(11):1759-67. View on Pubmed
  80. Hellmuth J, Valcour V, Spudich S. CNS reservoirs for HIV: implications for eradication. J Virus Erad. 2015 Apr; 1(2):67-71. View on Pubmed
  81. Wade BS, Valcour VG, Wendelken-Riegelhaupt L, Esmaeili-Firidouni P, Joshi SH, Wang Y, Thompson PM. MAPPING ABNORMAL SUBCORTICAL BRAIN MORPHOMETRY IN AN ELDERLY HIV+ COHORT. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:971-975. View on Pubmed
  82. Rubin LH, Cook JA, Weber KM, Cohen MH, Martin E, Valcour V, Milam J, Anastos K, Young MA, Alden C, Gustafson DR, Maki PM. The association of perceived stress and verbal memory is greater in HIV-infected versus HIV-uninfected women. J Neurovirol. 2015 Aug; 21(4):422-32. View on Pubmed
  83. Wade BS, Valcour V, Busovaca E, Esmaeili-Firidouni P, Joshi SH, Wang Y, Thompson PM. Subcortical shape and volume abnormalities in an elderly HIV+ cohort. Proc SPIE Int Soc Opt Eng. 2015 Mar 17; 9417. View on Pubmed
  84. Valcour V, Rubin LH, Tien P, Anastos K, Young M, Mack W, Cohen M, Golub ET, Crystal H, Maki PM. Human immunodeficiency virus (HIV) modulates the associations between insulin resistance and cognition in the current combination antiretroviral therapy (cART) era: a study of the Women's Interagency HIV Study (WIHS). J Neurovirol. 2015 Aug; 21(4):415-21. View on Pubmed
  85. Heaps JM, Sithinamsuwan P, Paul R, Lerdlum S, Pothisri M, Clifford D, Tipsuk S, Catella S, Busovaca E, Fletcher JL, Raudabaugh B, Ratto-Kim S, Valcour V, Ananworanich J. Association between brain volumes and HAND in cART-naïve HIV+ individuals from Thailand. J Neurovirol. 2015 Apr; 21(2):105-12. View on Pubmed
  86. Maki PM, Rubin LH, Valcour V, Martin E, Crystal H, Young M, Weber KM, Manly J, Richardson J, Alden C, Anastos K. Cognitive function in women with HIV: findings from the Women's Interagency HIV Study. Neurology. 2015 Jan 20; 84(3):231-40. View on Pubmed
  87. Ananworanich J, Datta AA, Fletcher JL, Townamchai N, Chomchey N, Kroon E, Sereti I, Valcour V, Kim JH. Acute tubular nephropathy in a patient with acute HIV infection: review of the literature. AIDS Res Ther. 2014; 11:34. View on Pubmed
  88. Paul RH, Joska JA, Woods C, Seedat S, Engelbrecht S, Hoare J, Heaps J, Valcour V, Ances B, Baker LM, Salminen LE, Stein DJ. Impact of the HIV Tat C30C31S dicysteine substitution on neuropsychological function in patients with clade C disease. J Neurovirol. 2014 Dec; 20(6):627-35. View on Pubmed
  89. Hellmuth J, Milanini B, Valcour V. Interactions between ageing and NeuroAIDS. Curr Opin HIV AIDS. 2014 Nov; 9(6):527-32. View on Pubmed
  90. Milanini B, Wendelken LA, Esmaeili-Firidouni P, Chartier M, Crouch PC, Valcour V. The Montreal cognitive assessment to screen for cognitive impairment in HIV patients older than 60 years. J Acquir Immune Defic Syndr. 2014 Sep 01; 67(1):67-70. View on Pubmed
  91. Kallianpur KJ, Valcour VG, Lerdlum S, Busovaca E, Agsalda M, Sithinamsuwan P, Chalermchai T, Fletcher JL, Tipsuk S, Shikuma CM, Shiramizu BT, Ananworanich J. HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patients naive to combination antiretroviral therapy. AIDS. 2014 Jul 17; 28(11):1619-24. View on Pubmed
  92. Kerr SJ, Puthanakit T, Vibol U, Aurpibul L, Vonthanak S, Kosalaraksa P, Kanjanavanit S, Hansudewechakul R, Wongsawat J, Luesomboon W, Ratanadilok K, Prasitsuebsai W, Pruksakaew K, van der Lugt J, Paul R, Ananworanich J, Valcour V. Neurodevelopmental outcomes in HIV-exposed-uninfected children versus those not exposed to HIV. AIDS Care. 2014; 26(11):1327-35. View on Pubmed
  93. Greene M, Steinman MA, McNicholl IR, Valcour V. Polypharmacy, drug-drug interactions, and potentially inappropriate medications in older adults with human immunodeficiency virus infection. J Am Geriatr Soc. 2014 Mar; 62(3):447-53. View on Pubmed
  94. Sithinamsuwan P, Hutchings N, Ananworanich J, Wendelken L, Saengtawan P, Paul R, Chomchey N, Fletcher JL, Chalermchai T, Valcour V. Practice effect and normative data of an HIV-specific neuropsychological testing battery among healthy Thais. J Med Assoc Thai. 2014 Feb; 97 Suppl 2:S222-33. View on Pubmed
  95. Gustafson DR, Mielke MM, Tien PC, Valcour V, Cohen M, Anastos K, Liu C, Pearce L, Golub ET, Minkoff H, Crystal HA. Anthropometric measures and cognition in middle-aged HIV-infected and uninfected women. The Women's Interagency HIV Study. J Neurovirol. 2013 Dec; 19(6):574-85. View on Pubmed
  96. Valcour VG, Ananworanich J, Agsalda M, Sailasuta N, Chalermchai T, Schuetz A, Shikuma C, Liang CY, Jirajariyavej S, Sithinamsuwan P, Tipsuk S, Clifford DB, Paul R, Fletcher JL, Marovich MA, Slike BM, DeGruttola V, Shiramizu B. HIV DNA reservoir increases risk for cognitive disorders in cART-naïve patients. PLoS One. 2013; 8(7):e70164. View on Pubmed
  97. Shikuma CM, McArthur JC, Ebenezer GJ, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Valcour VG, Bennett K, Phanuphak N. Ethnic differences in epidermal nerve fiber density. Muscle Nerve. 2013 Sep; 48(3):462-4. View on Pubmed
  98. Gardner RC, Valcour V, Yaffe K. Dementia in the oldest old: a multi-factorial and growing public health issue. Alzheimers Res Ther. 2013; 5(4):27. View on Pubmed
  99. Valcour VG. HIV, aging, and cognition: emerging issues. Top Antivir Med. 2013 Jul-Aug; 21(3):119-23. View on Pubmed
  100. Puthanakit T, Ananworanich J, Vonthanak S, Kosalaraksa P, Hansudewechakul R, van der Lugt J, Kerr SJ, Kanjanavanit S, Ngampiyaskul C, Wongsawat J, Luesomboon W, Vibol U, Pruksakaew K, Suwarnlerk T, Apornpong T, Ratanadilok K, Paul R, Mofenson LM, Fox L, Valcour V, Brouwers P, Ruxrungtham K. Cognitive function and neurodevelopmental outcomes in HIV-infected Children older than 1 year of age randomized to early versus deferred antiretroviral therapy: the PREDICT neurodevelopmental study. Pediatr Infect Dis J. 2013 May; 32(5):501-8. View on Pubmed
  101. Meyer VJ, Rubin LH, Martin E, Weber KM, Cohen MH, Golub ET, Valcour V, Young MA, Crystal H, Anastos K, Aouizerat BE, Milam J, Maki PM. HIV and recent illicit drug use interact to affect verbal memory in women. J Acquir Immune Defic Syndr. 2013 May 01; 63(1):67-76. View on Pubmed
  102. Kallianpur KJ, Shikuma C, Kirk GR, Shiramizu B, Valcour V, Chow D, Souza S, Nakamoto B, Sailasuta N. Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter. Neurology. 2013 May 07; 80(19):1792-9. View on Pubmed
  103. Greene M, Justice AC, Lampiris HW, Valcour V. Management of human immunodeficiency virus infection in advanced age. JAMA. 2013 Apr 03; 309(13):1397-405. View on Pubmed
  104. Chiao S, Rosen HJ, Nicolas K, Wendelken LA, Alcantar O, Rankin KP, Miller B, Valcour V. Deficits in self-awareness impact the diagnosis of asymptomatic neurocognitive impairment in HIV. AIDS Res Hum Retroviruses. 2013 Jun; 29(6):949-56. View on Pubmed
  105. Chalermchai T, Valcour V, Sithinamsuwan P, Pinyakorn S, Clifford D, Paul RH, Tipsuk S, Fletcher JL, Degruttola V, Ratto-Kim S, Hutchings N, Shikuma C, Ananworanich J. Trail Making Test A improves performance characteristics of the International HIV Dementia Scale to identify symptomatic HAND. J Neurovirol. 2013 Apr; 19(2):137-43. View on Pubmed
  106. Nir TM, Jahanshad N, Busovaca E, Wendelken L, Nicolas K, Thompson PM, Valcour VG. Mapping white matter integrity in elderly people with HIV. Hum Brain Mapp. 2014 Mar; 35(3):975-92. View on Pubmed
  107. Joseph J, Achim CL, Boivin MJ, Brew BJ, Clifford DB, Colosi DA, Ellis RJ, Heaton RK, Gallo-Diop A, Grant I, Kanmogne GD, Kumar M, Letendre S, Marcotte TD, Nath A, Pardo CA, Paul RH, Pulliam L, Robertson K, Royal W, Sacktor N, Sithinamsuwan P, Smith DM, Valcour V, Wigdahl B, Wood C. Global NeuroAIDS roundtable. J Neurovirol. 2013 Feb; 19(1):1-9. View on Pubmed
  108. Phanuphak N, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Kerr SJ, Chomchey N, Hongchookiat P, Mathajittiphun P, Pinyakorn S, Rungrojrat P, Praihirunyakit P, Gerschenson M, Phanuphak P, Valcour V, Kim JH, Shikuma C. A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine. Antivir Ther. 2012; 17(8):1521-31. View on Pubmed
  109. Sailasuta N, Ross W, Ananworanich J, Chalermchai T, DeGruttola V, Lerdlum S, Pothisri M, Busovaca E, Ratto-Kim S, Jagodzinski L, Spudich S, Michael N, Kim JH, Valcour V. Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection. PLoS One. 2012; 7(11):e49272. View on Pubmed
  110. Heaps J, Valcour V, Chalermchai T, Paul R, Rattanamanee S, Siangphoe U, Sithinamsuwan P, Chairangsaris P, Nidhinandana S, Tipsuk S, Suttichom D, Fletcher J, Shikuma C, Ananworanich J. Development of normative neuropsychological performance in Thailand for the assessment of HIV-associated neurocognitive disorders. J Clin Exp Neuropsychol. 2013; 35(1):1-8. View on Pubmed
  111. Shikuma CM, Nakamoto B, Shiramizu B, Liang CY, DeGruttola V, Bennett K, Paul R, Kallianpur K, Chow D, Gavegnano C, Hurwitz SJ, Schinazi RF, Valcour VG. Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV. Antivir Ther. 2012; 17(7):1233-42. View on Pubmed
  112. Bunupuradah T, Chetchotisakd P, Jirajariyavej S, Valcour V, Bowonwattanuwong C, Munsakul W, Klinbuayaem V, Prasithsirikul W, Sophonphan J, Mahanontharit A, Hirschel B, Bhakeecheep S, Ruxrungtham K, Ananworanich J. Neurocognitive impairment in patients randomized to second-line lopinavir/ritonavir-based antiretroviral therapy vs. lopinavir/ritonavir monotherapy. J Neurovirol. 2012 Dec; 18(6):479-87. View on Pubmed
  113. High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, Deren S, Effros RB, Gebo K, Goronzy JJ, Justice AC, Landay A, Levin J, Miotti PG, Munk RJ, Nass H, Rinaldo CR, Shlipak MG, Tracy R, Valcour V, Vance DE, Walston JD, Volberding P. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defic Syndr. 2012 Jul 01; 60 Suppl 1:S1-18. View on Pubmed
  114. Nakamoto BK, Jahanshad N, McMurtray A, Kallianpur KJ, Chow DC, Valcour VG, Paul RH, Marotz L, Thompson PM, Shikuma CM. Cerebrovascular risk factors and brain microstructural abnormalities on diffusion tensor images in HIV-infected individuals. J Neurovirol. 2012 Aug; 18(4):303-12. View on Pubmed
  115. Valcour V, Chalermchai T, Sailasuta N, Marovich M, Lerdlum S, Suttichom D, Suwanwela NC, Jagodzinski L, Michael N, Spudich S, van Griensven F, de Souza M, Kim J, Ananworanich J. Central nervous system viral invasion and inflammation during acute HIV infection. J Infect Dis. 2012 Jul 15; 206(2):275-82. View on Pubmed
  116. Wendelken LA, Valcour V. Impact of HIV and aging on neuropsychological function. J Neurovirol. 2012 Aug; 18(4):256-63. View on Pubmed
  117. Ananworanich J, Schuetz A, Vandergeeten C, Sereti I, de Souza M, Rerknimitr R, Dewar R, Marovich M, van Griensven F, Sekaly R, Pinyakorn S, Phanuphak N, Trichavaroj R, Rutvisuttinunt W, Chomchey N, Paris R, Peel S, Valcour V, Maldarelli F, Chomont N, Michael N, Phanuphak P, Kim JH. Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. PLoS One. 2012; 7(3):e33948. View on Pubmed
  118. Crystal H, Kleyman I, Anastos K, Lazar J, Cohen M, Liu C, Pearce L, Golub E, Valcour V, Ho A, Strickler H, Peters M, Kovacs A, Holman S, Kreek MJ, Manly J. Effects of hepatitis C and HIV on cognition in women: data from the Women's Interagency HIV Study. J Acquir Immune Defic Syndr. 2012 Feb 01; 59(2):149-54. View on Pubmed
  119. Kusao I, Shiramizu B, Liang CY, Grove J, Agsalda M, Troelstrup D, Velasco VN, Marshall A, Whitenack N, Shikuma C, Valcour V. Cognitive performance related to HIV-1-infected monocytes. J Neuropsychiatry Clin Neurosci. 2012; 24(1):71-80. View on Pubmed
  120. Jahanshad N, Valcour VG, Nir TM, Kohannim O, Busovaca E, Nicolas K, Thompson PM. Disrupted brain networks in the aging HIV+ population. Brain Connect. 2012; 2(6):335-44. View on Pubmed
  121. Shiramizu B, Ananworanich J, Chalermchai T, Siangphoe U, Troelstrup D, Shikuma C, De Grutolla V, Sithinamsuwan P, Praihirunkit P, Rattanamanee S, Valcour V. Failure to clear intra-monocyte HIV infection linked to persistent neuropsychological testing impairment after first-line combined antiretroviral therapy. J Neurovirol. 2012 Feb; 18(1):69-73. View on Pubmed
  122. Valcour VG. Evaluating cognitive impairment in the clinical setting: practical screening and assessment tools. Top Antivir Med. 2011 Dec; 19(5):175-80. View on Pubmed
  123. Shimizu SM, Chow DC, Valcour V, Masaki K, Nakamoto B, Kallianpur KJ, Shikuma C. The Impact of Depressive Symptoms on Neuropsychological Performance Tests in HIV-Infected Individuals: A Study of the Hawaii Aging with HIV Cohort. World J AIDS. 2011 Dec 01; 1(4):139-145. View on Pubmed
  124. Kallianpur KJ, Kirk GR, Sailasuta N, Valcour V, Shiramizu B, Nakamoto BK, Shikuma C. Regional cortical thinning associated with detectable levels of HIV DNA. Cereb Cortex. 2012 Sep; 22(9):2065-75. View on Pubmed
  125. Crystal HA, Weedon J, Holman S, Manly J, Valcour V, Cohen M, Anastos K, Liu C, Mack WJ, Golub E, Lazar J, Ho A, Kreek MJ, Kaplan RC. Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women. J Neurovirol. 2011 Oct; 17(5):469-76. View on Pubmed
  126. Valcour V, Maki P, Bacchetti P, Anastos K, Crystal H, Young M, Mack WJ, Cohen M, Golub ET, Tien PC. Insulin resistance and cognition among HIV-infected and HIV-uninfected adult women: the Women's Interagency HIV Study. AIDS Res Hum Retroviruses. 2012 May; 28(5):447-53. View on Pubmed
  127. Valcour V, Paul R, Chiao S, Wendelken LA, Miller B. Screening for cognitive impairment in human immunodeficiency virus. Clin Infect Dis. 2011 Oct; 53(8):836-42. View on Pubmed
  128. Nakamoto BK, Valcour VG, Kallianpur K, Liang CY, McMurtray A, Chow D, Kappenburg E, Shikuma CM. Impact of cerebrovascular disease on cognitive function in HIV-infected patients. J Acquir Immune Defic Syndr. 2011 Jul 01; 57(3):e66-8. View on Pubmed
  129. Perissinotto CM, Valcour V. Preventing dementia: is there hope for progress? Am Fam Physician. 2011 May 01; 83(9):1034-5. View on Pubmed
  130. Valcour V, Sithinamsuwan P, Letendre S, Ances B. Pathogenesis of HIV in the central nervous system. Curr HIV/AIDS Rep. 2011 Mar; 8(1):54-61. View on Pubmed
  131. Valcour V, Paul R, Neuhaus J, Shikuma C. The Effects of Age and HIV on Neuropsychological Performance. J Int Neuropsychol Soc. 2011 Jan; 17(1):190-5. View on Pubmed
  132. Crystal HA, Hamon S, Randesi M, Cook J, Anastos K, Lazar J, Liu C, Pearce L, Golub E, Valcour V, Weber KM, Holman S, Ho A, Kreek MJ. A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women. Addict Biol. 2012 Jan; 17(1):181-91. View on Pubmed
  133. Joska JA, Combrinck M, Valcour VG, Hoare J, Leisegang F, Mahne AC, Myer L, Stein DJ. Association between apolipoprotein E4 genotype and human immunodeficiency virus-associated dementia in younger adults starting antiretroviral therapy in South Africa. J Neurovirol. 2010 Oct; 16(5):377-83. View on Pubmed
  134. Nakamoto BK, McMurtray A, Davis J, Valcour V, Watters MR, Shiramizu B, Chow DC, Kallianpur K, Shikuma CM. Incident neuropathy in HIV-infected patients on HAART. AIDS Res Hum Retroviruses. 2010 Jul; 26(7):759-65. View on Pubmed
  135. Valcour VG, Shiramizu BT, Shikuma CM. HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications. J Leukoc Biol. 2010 Apr; 87(4):621-6. View on Pubmed
  136. Pumpradit W, Ananworanich J, Lolak S, Shikuma C, Paul R, Siangphoe U, Chaoniti N, Kaew-On P, Paris R, Ruxrungtham K, Valcour V. Neurocognitive impairment and psychiatric comorbidity in well-controlled human immunodeficiency virus-infected Thais from the 2NN Cohort Study. J Neurovirol. 2010 Feb; 16(1):76-82. View on Pubmed
  137. Valcour V. Aging with HIV. Lessons from CROI 2009. Posit Aware. 2009 May-Jun; 20(3):37-9. View on Pubmed
  138. Valcour VG, Shiramizu BT, Sithinamsuwan P, Nidhinandana S, Ratto-Kim S, Ananworanich J, Siangphoe U, Kim JH, de Souza M, Degruttola V, Paul RH, Shikuma CM. HIV DNA and cognition in a Thai longitudinal HAART initiation cohort: the SEARCH 001 Cohort Study. Neurology. 2009 Mar 17; 72(11):992-8. View on Pubmed
  139. Valcour V, Yeh TM, Bartt R, Clifford D, Gerschenson M, Evans SR, Cohen BA, Ebenezer GJ, Hauer P, Millar L, Gould M, Tran P, Shikuma C, Souza S, McArthur JC. Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection. HIV Med. 2009 Feb; 10(2):103-10. View on Pubmed
  140. Shiramizu B, Williams AE, Shikuma C, Valcour V. Amount of HIV DNA in peripheral blood mononuclear cells is proportional to the severity of HIV-1-associated neurocognitive disorders. J Neuropsychiatry Clin Neurosci. 2009; 21(1):68-74. View on Pubmed
  141. Sithinamsuwan P, Punthanamongkol S, Valcour V, Onsanit S, Nidhinandana S, Thitivichianlert S, Shikuma C. Frequency and characteristics of HIV-associated sensory neuropathy among HIV patients in Bangkok, Thailand. J Acquir Immune Defic Syndr. 2008 Dec 01; 49(4):456-8. View on Pubmed
  142. Valcour V, Watters MR, Williams AE, Sacktor N, McMurtray A, Shikuma C. Aging exacerbates extrapyramidal motor signs in the era of highly active antiretroviral therapy. J Neurovirol. 2008 Oct; 14(5):362-7. View on Pubmed
  143. Valcour V, Shiramizu B, Shikuma C. Frequency of apolipoprotein E4 among older compared with younger HIV patients: support for detrimental effect of E4 on survival. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):E66; author reply E67-8. View on Pubmed
  144. McMurtray A, Nakamoto B, Shikuma C, Valcour V. Cortical atrophy and white matter hyperintensities in HIV: the Hawaii Aging with HIV Cohort Study. J Stroke Cerebrovasc Dis. 2008 Jul-Aug; 17(4):212-7. View on Pubmed
  145. Valcour V, Haman A, Cornes S, Lawall C, Parsa AT, Glaser C, Yagi S, Tihan T, Bhatnagar J, Geschwind M. A case of enteroviral meningoencephalitis presenting as rapidly progressive dementia. Nat Clin Pract Neurol. 2008 Jul; 4(7):399-403. View on Pubmed
  146. Ratto-Kim S, Chuenchitra T, Pulliam L, Paris R, Sukwit S, Gongwon S, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Shiramizu BT, de Souza MS, Chitpatima ST, Sun B, Rempel H, Nitayaphan S, Williams K, Kim JH, Shikuma CM, Valcour VG. Expression of monocyte markers in HIV-1 infected individuals with or without HIV associated dementia and normal controls in Bangkok Thailand. J Neuroimmunol. 2008 Mar; 195(1-2):100-7. View on Pubmed
  147. Evans SR, Yeh TM, Sacktor N, Clifford DB, Simpson D, Miller EN, Ellis RJ, Valcour V, Marra CM, Millar L, Schifitto G. Selegiline transdermal system (STS) for HIV-associated cognitive impairment: open-label report of ACTG 5090. HIV Clin Trials. 2007 Nov-Dec; 8(6):437-46. View on Pubmed
  148. Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, Pulliam L, Robertson KR, Sacktor N, Valcour V, Wojna VE. Updated research nosology for HIV-associated neurocognitive disorders. Neurology. 2007 Oct 30; 69(18):1789-99. View on Pubmed
  149. Schifitto G, Zhang J, Evans SR, Sacktor N, Simpson D, Millar LL, Hung VL, Miller EN, Smith E, Ellis RJ, Valcour V, Singer E, Marra CM, Kolson D, Weihe J, Remmel R, Katzenstein D, Clifford DB. A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment. Neurology. 2007 Sep 25; 69(13):1314-21. View on Pubmed
  150. McMurtray A, Nakamoto B, Shikuma C, Valcour V. Small-vessel vascular disease in human immunodeficiency virus infection: the Hawaii aging with HIV cohort study. Cerebrovasc Dis. 2007; 24(2-3):236-41. View on Pubmed
  151. Zhou L, Kitch DW, Evans SR, Hauer P, Raman S, Ebenezer GJ, Gerschenson M, Marra CM, Valcour V, Diaz-Arrastia R, Goodkin K, Millar L, Shriver S, Asmuth DM, Clifford DB, Simpson DM, McArthur JC. Correlates of epidermal nerve fiber densities in HIV-associated distal sensory polyneuropathy. Neurology. 2007 Jun 12; 68(24):2113-9. View on Pubmed
  152. Sacktor N, Skolasky R, Selnes OA, Watters M, Poff P, Shiramizu B, Shikuma C, Valcour V. Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals. J Neurovirol. 2007 Jun; 13(3):203-9. View on Pubmed
  153. Valcour VG, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Ratto-Kim S, Apateerapong W, Shiramizu BT, Desouza MS, Chitpatima ST, Watt G, Chuenchitra T, Robertson KR, Paul RH, McArthur JC, Kim JH, Shikuma CM. Neuropsychological abnormalities in patients with dementia in CRF 01_AE HIV-1 infection. Neurology. 2007 Feb 13; 68(7):525-7. View on Pubmed
  154. Shiramizu B, Paul R, Williams A, Shikuma C, Watters M, Grove J, Valcour V. HIV proviral DNA associated with decreased neuropsychological function. J Neuropsychiatry Clin Neurosci. 2007; 19(2):157-63. View on Pubmed
  155. Shiramizu B, Ratto-Kim S, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Watt G, deSouza M, Chuenchitra T, Sukwit S, Chitpatima S, Robertson K, Paul R, Shikuma C, Valcour V. HIV DNA and dementia in treatment-naïve HIV-1-infected individuals in Bangkok, Thailand. Int J Med Sci. 2006 Dec 06; 4(1):13-8. View on Pubmed
  156. Valcour VG, Sacktor NC, Paul RH, Watters MR, Selnes OA, Shiramizu BT, Williams AE, Shikuma CM. Insulin resistance is associated with cognition among HIV-1-infected patients: the Hawaii Aging With HIV cohort. J Acquir Immune Defic Syndr. 2006 Dec 01; 43(4):405-10. View on Pubmed
  157. Valcour V, Yee P, Williams AE, Shiramizu B, Watters M, Selnes O, Paul R, Shikuma C, Sacktor N. Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infection--The Hawaii Aging with HIV Cohort. J Neurovirol. 2006 Oct; 12(5):387-91. View on Pubmed
  158. Valcour V, Paul R. HIV infection and dementia in older adults. Clin Infect Dis. 2006 May 15; 42(10):1449-54. View on Pubmed
  159. Tokuhara KG, Valcour VG, Masaki KH, Blanchette PL. Utility of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for dementia in a Japanese-American population. Hawaii Med J. 2006 Mar; 65(3):72-5. View on Pubmed
  160. Kalayjian RC, Spritzler J, Pu M, Landay A, Pollard RB, Stocker V, Harthi LA, Gross BH, Francis IR, Fiscus SA, Tebas P, Bosch RJ, Valcour V, Lederman MM. Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease. J Infect Dis. 2005 Nov 01; 192(9):1577-87. View on Pubmed
  161. Killebrew DA, Troelstrup D, Valcour V, Williams A, Aguon J, Sapalo D, Shikuma C, Ratto-Kim S, Shiramizu B. Discordant plasma and cerebral spinal fluid cytokines/chemokines in relation to HIV-1-associated dementia. Cell Mol Biol (Noisy-le-grand). 2005 Sep 02; 51 Suppl:OL745-54. View on Pubmed
  162. Shikuma CM, Valcour VG, Ratto-Kim S, Williams AE, Souza S, Gerschenson M, Day L, Kim JH, Shiramizu B. HIV-associated wasting in the era of highly active antiretroviral therapy: a syndrome of residual HIV infection in monocytes and macrophages? Clin Infect Dis. 2005 Jun 15; 40(12):1846-8. View on Pubmed
  163. Shiramizu B, Gartner S, Williams A, Shikuma C, Ratto-Kim S, Watters M, Aguon J, Valcour V. Circulating proviral HIV DNA and HIV-associated dementia. AIDS. 2005 Jan 03; 19(1):45-52. View on Pubmed
  164. Valcour VG, Shikuma CM, Shiramizu BT, Williams AE, Watters MR, Poff PW, Grove JS, Selnes OA, Sacktor NC. Diabetes, insulin resistance, and dementia among HIV-1-infected patients. J Acquir Immune Defic Syndr. 2005 Jan 01; 38(1):31-6. View on Pubmed
  165. Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes OA, Grove J, Liu Y, Abdul-Majid KB, Gartner S, Sacktor N. Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii Aging with HIV Cohort. J Neuroimmunol. 2004 Dec; 157(1-2):197-202. View on Pubmed
  166. Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes O, Holck P, Grove J, Sacktor N. Higher frequency of dementia in older HIV-1 individuals: the Hawaii Aging with HIV-1 Cohort. Neurology. 2004 Sep 14; 63(5):822-7. View on Pubmed
  167. Valcour V, Shiramizu B. HIV-associated dementia, mitochondrial dysfunction, and oxidative stress. Mitochondrion. 2004 Jul; 4(2-3):119-29. View on Pubmed
  168. Watters MR, Poff PW, Shiramizu BT, Holck PS, Fast KM, Shikuma CM, Valcour VG. Symptomatic distal sensory polyneuropathy in HIV after age 50. Neurology. 2004 Apr 27; 62(8):1378-83. View on Pubmed
  169. Shiramizu B, Gartner S, Cho M, Liu Y, Pyron N, Valcour V, Shikuma C. Assessment of HIV-1 DNA copies per cell by real-time polymerase chain reaction. Front Biosci. 2004 Jan 01; 9:255-61. View on Pubmed
  170. Valcour VG, Shikuma CM, Watters MR, Sacktor NC. Cognitive impairment in older HIV-1-seropositive individuals: prevalence and potential mechanisms. AIDS. 2004 Jan 01; 18 Suppl 1:S79-86. View on Pubmed
  171. Fernandes R, Valcour V, Flynn B, Masaki K, Blanchette P. Tetanus immunity in long-term care facilities. J Am Geriatr Soc. 2003 Aug; 51(8):1116-9. View on Pubmed
  172. Valcour VG, Masaki KH, Blanchette PL. Self-reported driving, cognitive status, and physician awareness of cognitive impairment. J Am Geriatr Soc. 2002 Jul; 50(7):1265-7. View on Pubmed
  173. Valcour VG, Masaki KH, Blanchette PL. The phrase: "no ifs, ands, or buts" and cognitive testing. Lessons from an Asian-American community. Hawaii Med J. 2002 Apr; 61(4):72-4. View on Pubmed
  174. Valcour VG, Masaki KH, Curb JD, Blanchette PL. The detection of dementia in the primary care setting. Arch Intern Med. 2000 Oct 23; 160(19):2964-8. View on Pubmed
  175. Cooper TA, Valcour VG, Gibbons RB, O'Brien-Falls K. Spontaneous ecchymoses due to paroxetine administration. Am J Med. 1998 Feb; 104(2):197-8. View on Pubmed