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Adithya Cattamanchi, MD, MAS
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Professor, School of Medicine
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Biography
My research is focused on two thematic areas: 1) Development and evaluation of tuberculosis (TB) diagnostics and 2) Implementation and dissemination of evidence-based preventative, diagnostic, and treatment interventions for TB. I have considerable experience with the evaluation of TB diagnostics in low-income countries, including studying the impact of new diagnostics on patient- and public health-important outcomes. I have served on several World Health Organization (WHO) Expert Group panels to develop new policies related to TB diagnostics and serve as a faculty member for the Advanced Tuberculosis Diagnostics Research workshop sponsored by the WHO Stop TB Partnership. I have initiated a number of collaborations with engineers in industry and academia to develop and evaluate new diagnostic platforms for TB including: 1) mobile phone-based microscopy; 2) mobile phone-based molecular diagnostic platforms; and 3) single-particle aerosol mass spectrometry. We are currently evaluating the mobile phone-based microscopy platform and health centers in Hanoi, Vietnam in a demonstration project funded by the TB REACH initiative.
In addition to research on TB diagnostics, I have developed an active research agenda related to implementation science. I helped establish a platform for monitoring the quality of TB care at 6 rural health centers in Uganda (Uganda Tuberculosis Surveillance Project). My current work, supported through an NIH/NIAID R21 in Implementation and Dissemination Science, is focused on improving the quality of TB suspect evaluation at these health centers.
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Displaying 51 - 75 of 202
- Mwebe SZ, Yoon C, Asege L, Nakaye M, Katende J, Andama A, Cattamanchi A, Semitala FC. Impact of hematocrit on point-of-care C-reactive protein-based tuberculosis screening among people living with HIV initiating antiretroviral therapy in Uganda. Diagn Microbiol Infect Dis. 2021 Mar; 99(3):115281.
- Zawedde-Muyanja S, Musaazi J, Manabe YC, Katamba A, Nankabirwa JI, Castelnuovo B, Cattamanchi A. Estimating the effect of pretreatment loss to follow up on TB associated mortality at public health facilities in Uganda. PLoS One. 2020; 15(11):e0241611.
- Kadota JL, Reza TF, Nalugwa T, Kityamuwesi A, Nanyunja G, Kiwanuka N, Shete P, Davis JL, Dowdy D, Turyahabwe S, Katamba A, Cattamanchi A. Impact of shelter-in-place on TB case notifications and mortality during the COVID-19 pandemic. Int J Tuberc Lung Dis. 2020 11 01; 24(11):1212-1214.
- Rupani MP, Cattamanchi A, Shete PB, Vollmer WM, Basu S, Dave JD. Costs incurred by patients with drug-susceptible pulmonary tuberculosis in semi-urban and rural settings of Western India. Infect Dis Poverty. 2020 Oct 19; 9(1):144.
- Berger C, Patel D, Kityamuwesi A, Ggita J, Tinka LK, Turimumahoro P, Neville K, Chehab L, Chen AZ, Gupta N, Turyahabwe S, Katamba A, Cattamanchi A, Sammann A. Opportunities to improve digital adherence technologies and TB care using human-centered design. Int J Tuberc Lung Dis. 2020 10 01; 24(10):1112-1115.
- Berger CA, Kityamuwesi A, Crowder R, Lamunu M, Kunihira Tinka L, Ggita J, Sanyu Nakate A, Namale C, Oyuku D, Chen K, Turyahabwe S, Cattamanchi A, Katamba A. Variation in tuberculosis treatment outcomes and treatment supervision practices in Uganda. J Clin Tuberc Other Mycobact Dis. 2020 Dec; 21:100184.
- Magni R, Rruga F, Alsaab F, Sharif S, Howard M, Espina V, Kim B, Lepene B, Lee G, Alayouni MA, Steinberg H, Araujo R, Kashanchi F, Riccardi F, Morreira S, Araujo A, Poli F, Jaganath D, Semitala FC, Worodria W, Andama A, Choudhary A, Honnen WJ, Petricoin EF, Cattamanchi A, Colombatti R, de Waard JH, Oberhelman R, Pinter A, Gilman RH, Liotta LA, Luchini A. Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes. Sci Rep. 2020 08 18; 10(1):13944.
- Kadota JL, Musinguzi A, Nabunje J, Welishe F, Ssemata JL, Bishop O, Berger CA, Patel D, Sammann A, Katahoire A, Nahid P, Belknap R, Phillips PPJ, Namusobya J, Kamya M, Handley MA, Kiwanuka N, Katamba A, Dowdy D, Semitala FC, Cattamanchi A. Protocol for the 3HP Options Trial: a hybrid type 3 implementation-effectiveness randomized trial of delivery strategies for short-course tuberculosis preventive therapy among people living with HIV in Uganda. Implement Sci. 2020 08 12; 15(1):65.
- Kadota JL, Katamba A, Musinguzi A, Welishe F, Nabunje J, Ssemata JL, Berger CA, Kamya MR, Namusobya J, Semitala FC, Cattamanchi A, Dowdy DW. Willingness to accept reimbursement for visits to an HIV clinic for tuberculosis preventive therapy. Int J Tuberc Lung Dis. 2020 07 01; 24(7):729-731.
- Vivek Jain, Lillian B Brown, Carina Marquez, Luis Rubio, Natasha Spottiswoode, Bethlehem Churnet, Katherine Brooks, Mengyu Zhou, Timothy Muldoon, Carolyn Hendrickson, Adithya Cattamanchi, Antonio Gomez, Brian Haas, Edwin Charlebois, Annie Luetkemeyer, Annie Luetkemeyer, Monica Gandhi, Diane Havlir, Sumant Ranji, Lisa Gail Winston. 448. Disproportionate Burden of COVID-19 on Latinx Residents among Hospitalized Patients at San Francisco’s Public Health Hospital. Open Forum Infectious Diseases. 2020 Dec 31; 7(Suppl 1):s292-s292.
- Vanderburg S, Alipanah N, Crowder R, Yoon C, Wang R, Thakur N, Slown K, Shete PB, Rofael M, Metcalfe JZ, Merrifield C, Marquez C, Malcolm K, Lipnick M, Jain V, Gomez A, Burns G, Brown LB, Berger C, Auyeung V, Cattamanchi A, Hendrickson CM. Management and Outcomes of Critically-Ill Patients with COVID-19 Pneumonia at a Safety-net Hospital in San Francisco, a Region with Early Public Health Interventions: A Case Series. medRxiv. 2020 May 29.
- Shete PB, Gonzales R, Ackerman S, Cattamanchi A, Handley MA. The University of California San Francisco (UCSF) Training Program in Implementation Science: Program Experiences and Outcomes. Front Public Health. 2020; 8:94.
- Shete PB, Gonzales R, Ackerman S, Cattamanchi A, Handley MA. The University of California San Francisco (UCSF) Training Program in Implementation Science: Program Experiences and Outcomes. Front Public Health. 2020; 8:94.
- Kerkhoff AD, Muyoyeta M, Cattamanchi A. Community-wide Screening for Tuberculosis. N Engl J Med. 2020 03 19; 382(12):1185-1186.
- Gupta N, Cattamanchi A, Cabana MD, Jennings B, Parikh K, Kaiser SV. Implementing pediatric inpatient asthma pathways. J Asthma. 2021 Jul; 58(7):893-902.
- Nalugwa T, Shete PB, Nantale M, Farr K, Ojok C, Ochom E, Mugabe F, Joloba M, Dowdy DW, Moore DAJ, Davis JL, Cattamanchi A, Katamba A. Challenges with scale-up of GeneXpert MTB/RIF® in Uganda: a health systems perspective. BMC Health Serv Res. 2020 Mar 04; 20(1):162.
- Cattamanchi A, Berger CA, Shete PB, Turyahabwe S, Joloba M, Moore DA, Davis LJ, Katamba A. Implementation science to improve the quality of tuberculosis diagnostic services in Uganda. J Clin Tuberc Other Mycobact Dis. 2020 Feb; 18:100136.
- Semitala FC, Cattamanchi A, Andama A, Atuhumuza E, Katende J, Mwebe S, Asege L, Nakaye M, Kamya MR, Yoon C. Brief Report: Yield and Efficiency of Intensified Tuberculosis Case-Finding Algorithms in 2 High-Risk HIV Subgroups in Uganda. J Acquir Immune Defic Syndr. 2019 12 01; 82(4):416-420.
- Nahid P, Mase SR, Migliori GB, Sotgiu G, Bothamley GH, Brozek JL, Cattamanchi A, Cegielski JP, Chen L, Daley CL, Dalton TL, Duarte R, Fregonese F, Horsburgh CR, Ahmad Khan F, Kheir F, Lan Z, Lardizabal A, Lauzardo M, Mangan JM, Marks SM, McKenna L, Menzies D, Mitnick CD, Nilsen DM, Parvez F, Peloquin CA, Raftery A, Schaaf HS, Shah NS, Starke JR, Wilson JW, Wortham JM, Chorba T, Seaworth B. Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline. Am J Respir Crit Care Med. 2019 11 15; 200(10):e93-e142.
- Ochodo EA, Kalema N, Schumacher S, Steingart K, Young T, Mallett S, Deeks J, Cobelens F, Bossuyt PM, Nicol MP, Cattamanchi A. Variation in the observed effect of Xpert MTB/RIF testing for tuberculosis on mortality: A systematic review and analysis of trial design considerations. Wellcome Open Res. 2019; 4:173.
- Murugesan K, Hogan CA, Palmer Z, Reeve B, Theron G, Andama A, Somoskovi A, Steadman A, Madan D, Andrews J, Croda J, Sahoo MK, Cattamanchi A, Pinsky BA, Banaei N. Investigation of Preanalytical Variables Impacting Pathogen Cell-Free DNA in Blood and Urine. J Clin Microbiol. 2019 11; 57(11).
- Nathavitharana RR, Yoon C, Macpherson P, Dowdy DW, Cattamanchi A, Somoskovi A, Broger T, Ottenhoff THM, Arinaminpathy N, Lonnroth K, Reither K, Cobelens F, Gilpin C, Denkinger CM, Schumacher SG. Guidance for Studies Evaluating the Accuracy of Tuberculosis Triage Tests. J Infect Dis. 2019 10 08; 220(220 Suppl 3):S116-S125.
- Agins BD, Ikeda DJ, Reid MJA, Goosby E, Pai M, Cattamanchi A. Improving the cascade of global tuberculosis care: moving from the "what" to the "how" of quality improvement. Lancet Infect Dis. 2019 12; 19(12):e437-e443.
- Davis JL, Turimumahoro P, Meyer AJ, Ayakaka I, Ochom E, Ggita J, Mark D, Babirye D, Okello DA, Mugabe F, Fair E, Vittinghoff E, Armstrong-Hough M, Dowdy D, Cattamanchi A, Haberer JE, Katamba A. Home-based tuberculosis contact investigation in Uganda: a household randomised trial. ERJ Open Res. 2019 Jul; 5(3).
- Davis JL, Turimumahoro P, Meyer AJ, Ayakaka I, Ochom E, Ggita J, Mark D, Babirye D, Okello DA, Mugabe F, Fair E, Vittinghoff E, Armstrong-Hough M, Dowdy D, Cattamanchi A, Haberer JE, Katamba A. Home-based tuberculosis contact investigation in Uganda: a household randomised trial. ERJ Open Res. 2019 Jul; 5(3).