Single-Cell Sequencing Interest Group (SSIG)

Single cell and spatial approaches for uncovering mechanisms of lung disease

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UCSF Pride Hall Room 5105 + Zoom

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Single cell and spatial approaches for uncovering mechanisms of lung disease

Associate Professor, Medicine 
Director, Genomics CoLab

Walter Eckalbar is a genomic scientist with a broad background in applying molecular genetic, functional genomic and bioinformatic approaches to investigate topics ranging from human disease to development and evolution. As a Ph.D. student and a postdoctoral scholar, Dr. Eckalbar used RNA-seq, ChIP-seq, ATAC-seq and other functional genomic assays to characterize the response to drug treatment, explore the gene regulatory effects of disease-associated variants, and identify the regulatory changes involved in the development and evolution of bat wings. Currently, as an Associate Professor in Pulmonary Division and the Director of the Genomics CoLab at UCSF, Dr. Eckalbar’s research program focus on utilizing genomic technologies, including CRISPR screens and massively parallel reporter assays, to investigate the genetic mechanisms underlying asthma and asthma drug response. The Genomics CoLab represents a novel model for a research lab that aims to adapt and develop advanced genomic assays, recently including multiple spatial transcriptomics platforms for independent, collaborative and service-based research projects across the UCSF community.