Todd Margolis, MD, PhD

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Todd Margolis, MD, PhD

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Professor Emeritus, Chancellor/EVC/FAS
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Biography

Margolis, a UCSF professor of ophthalmology, is the director of the Francis I. Proctor Foundation for Research in Ophthalmology at UCSF Medical Center. He is also president of the Association for Research in Vision and Ophthalmology, the world's largest eye and vision research organization, and serves on the National Advisory Eye Council of the National Eye Institute. He received his MD and his PhD degrees in neuroscience at UCSF.
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  1. Bertke AS, Ma A, Margolis MS, Margolis TP. Different mechanisms regulate productive herpes simplex virus 1 (HSV-1) and HSV-2 infections in adult trigeminal neurons. J Virol. 2013 Jun; 87(11):6512-6.
  2. Heiden D, Margolis TP, Lowinger A, Saranchuk P. Eye exam with indirect ophthalmoscopy for diagnosis of disseminated tuberculosis in patients with HIV/AIDS. Br J Ophthalmol. 2013 May; 97(5):668-9.
  3. Bertke AS, Apakupakul K, Ma A, Imai Y, Gussow AM, Wang K, Cohen JI, Bloom DC, Margolis TP. LAT region factors mediating differential neuronal tropism of HSV-1 and HSV-2 do not act in trans. PLoS One. 2012; 7(12):e53281.
  4. Fintelmann RE, Vastine DW, Bloomer MM, Margolis TP. Thygeson superficial punctate keratitis and scarring. Cornea. 2012 Dec; 31(12):1446-8.
  5. Gonzales JA, Levison AL, Stewart JM, Acharya NR, Margolis TP. Retinal necrosis following varicella-zoster vaccination. Arch Ophthalmol. 2012 Oct; 130(10):1355-6.
  6. Sy A, McLeod SD, Cohen EJ, Margolis TP, Mannis MJ, Lietman TM, Acharya NR. Practice patterns and opinions in the management of recurrent or chronic herpes zoster ophthalmicus. Cornea. 2012 Jul; 31(7):786-90.
  7. Smits SL, Manandhar A, van Loenen FB, van Leeuwen M, Baarsma GS, Dorrestijn N, Osterhaus AD, Margolis TP, Verjans GM. High prevalence of anelloviruses in vitreous fluid of children with seasonal hyperacute panuveitis. J Infect Dis. 2012 Jun 15; 205(12):1877-84.
  8. Dalmon C, Porco TC, Lietman TM, Prajna NV, Prajna L, Das MR, Kumar JA, Mascarenhas J, Margolis TP, Whitcher JP, Jeng BH, Keenan JD, Chan MF, McLeod SD, Acharya NR. The clinical differentiation of bacterial and fungal keratitis: a photographic survey. Invest Ophthalmol Vis Sci. 2012 Apr 02; 53(4):1787-91.
  9. Chen J, Ausayakhun S, Tangmonkongvoragul C, Ausayakhun S, Jirawison C, Margolis TP, Keenan JD. Incidence of cytomegalovirus retinitis in patients with human immunodeficiency virus following negative initial screening examination results. Arch Ophthalmol. 2012 Apr; 130(4):527-9.
  10. Ausayakhun S, Keenan JD, Ausayakhun S, Jirawison C, Khouri CM, Skalet AH, Heiden D, Holland GN, Margolis TP. Clinical features of newly diagnosed cytomegalovirus retinitis in northern Thailand. Am J Ophthalmol. 2012 May; 153(5):923-931.e1.
  11. Chen J, Ausayakhun S, Ausayakhun S, Jirawison C, Khouri CM, Porco TC, Heiden D, Keenan JD, Margolis TP. Comparison of autophotomontage software programs in eyes with CMV retinitis. Invest Ophthalmol Vis Sci. 2011 Dec 09; 52(13):9339-44.
  12. Ausayakhun S, Skalet AH, Jirawison C, Ausayakhun S, Keenan JD, Khouri C, Nguyen K, Kalyani PS, Heiden D, Holland GN, Margolis TP. Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis. Am J Ophthalmol. 2011 Dec; 152(6):1053-1058.e1.
  13. Tun N, London N, Kyaw MK, Smithuis F, Ford N, Margolis T, Drew WL, Lewallen S, Heiden D. CMV retinitis screening and treatment in a resource-poor setting: three-year experience from a primary care HIV/AIDS programme in Myanmar. J Int AIDS Soc. 2011 Aug 15; 14:41.
  14. Keenan JD, Mandel MR, Margolis TP. Peripheral ulcerative keratitis associated with vasculitis manifesting asymmetrically as fuchs superficial marginal keratitis and terrien marginal degeneration. Cornea. 2011 Jul; 30(7):825-7.
  15. Bertke AS, Swanson SM, Chen J, Imai Y, Kinchington PR, Margolis TP. A5-positive primary sensory neurons are nonpermissive for productive infection with herpes simplex virus 1 in vitro. J Virol. 2011 Jul; 85(13):6669-77.
  16. Tang S, Bertke AS, Patel A, Margolis TP, Krause PR. Herpes simplex virus 2 microRNA miR-H6 is a novel latency-associated transcript-associated microRNA, but reduction of its expression does not influence the establishment of viral latency or the recurrence phenotype. J Virol. 2011 May; 85(9):4501-9.
  17. Khalifa YM, Bloomer MM, Margolis TP. Secondary localized sectoral keratoconjunctival amyloidosis from ocular trauma. Cornea. 2010 Nov; 29(11):1328-9.
  18. Jeng BH, Gritz DC, Kumar AB, Holsclaw DS, Porco TC, Smith SD, Whitcher JP, Margolis TP, Wong IG. Epidemiology of ulcerative keratitis in Northern California. Arch Ophthalmol. 2010 Aug; 128(8):1022-8.
  19. Khalifa YM, Jacoby RM, Margolis TP. Exacerbation of zoster interstitial keratitis after zoster vaccination in an adult. Arch Ophthalmol. 2010 Aug; 128(8):1079-80.
  20. Narkewicz MR, Rosenthal P, Schwarz KB, Drack A, Margolis T, Repka MX, PEDS-C Study Group . Ophthalmologic complications in children with chronic hepatitis C treated with pegylated interferon. J Pediatr Gastroenterol Nutr. 2010 Aug; 51(2):183-6.
  21. Cohen JI, Fahle G, Kemp MA, Apakupakul K, Margolis TP. Human herpesvirus 6-A, 6-B, and 7 in vitreous fluid samples. J Med Virol. 2010 May; 82(6):996-9.
  22. Keenan JD, Fram NR, McLeod SD, Strauss EC, Margolis TP. Perifosine-related rapidly progressive corneal ring infiltrate. Cornea. 2010 May; 29(5):583-5.
  23. Lin P, Loh AR, Margolis TP, Acharya NR. Cigarette smoking as a risk factor for uveitis. Ophthalmology. 2010 Mar; 117(3):585-90.
  24. Hu AY, Strauss EC, Holland GN, Chan MF, Yu F, Margolis TP. Late varicella-zoster virus dendriform keratitis in patients with histories of herpes zoster ophthalmicus. Am J Ophthalmol. 2010 Feb; 149(2):214-220.e3.
  25. Bertke AS, Patel A, Imai Y, Apakupakul K, Margolis TP, Krause PR. Latency-associated transcript (LAT) exon 1 controls herpes simplex virus species-specific phenotypes: reactivation in the guinea pig genital model and neuron subtype-specific latent expression of LAT. J Virol. 2009 Oct; 83(19):10007-15.