Todd Margolis, MD, PhD

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Todd Margolis, MD, PhD

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Professor Emeritus, Chancellor/EVC/FAS
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Biography

Margolis, a UCSF professor of ophthalmology, is the director of the Francis I. Proctor Foundation for Research in Ophthalmology at UCSF Medical Center. He is also president of the Association for Research in Vision and Ophthalmology, the world's largest eye and vision research organization, and serves on the National Advisory Eye Council of the National Eye Institute. He received his MD and his PhD degrees in neuroscience at UCSF.
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  1. Imai Y, Apakupakul K, Krause PR, Halford WP, Margolis TP. Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia. J Virol. 2009 Aug; 83(16):7873-82.
  2. Wang K, Mahalingam G, Imai Y, Pesnicak L, Margolis TP, Margolis TT, Straus SE, Cohen JI. Cell type specific accumulation of the major latency-associated transcript (LAT) of herpes simplex virus type 2 in LAT transgenic mice. Virology. 2009 Mar 30; 386(1):79-87.
  3. Nagpal A, Vora R, Margolis TP, Acharya NR. Interstitial keratitis following varicella vaccination. Arch Ophthalmol. 2009 Feb; 127(2):222-3.
  4. Leigh JF, Acharya N, Cevallos V, Margolis TP. Does asymptomatic shedding of herpes simplex virus on the ocular surface lead to false-positive diagnostic PCR results? Br J Ophthalmol. 2008 Mar; 92(3):435-6.
  5. Heiden D, Ford N, Wilson D, Rodriguez WR, Margolis T, Janssens B, Bedelu M, Tun N, Goemaere E, Saranchuk P, Sabapathy K, Smithuis F, Luyirika E, Drew WL. Cytomegalovirus retinitis: the neglected disease of the AIDS pandemic. PLoS Med. 2007 Dec; 4(12):e334.
  6. Margolis TP, Elfman FL, Leib D, Pakpour N, Apakupakul K, Imai Y, Voytek C. Spontaneous reactivation of herpes simplex virus type 1 in latently infected murine sensory ganglia. J Virol. 2007 Oct; 81(20):11069-74.
  7. Acharya NR, Lietman TM, Margolis TP. Parasites on the rise: a new epidemic of Acanthamoeba keratitis. Am J Ophthalmol. 2007 Aug; 144(2):292-3.
  8. Freidlin J, Acharya N, Lietman TM, Cevallos V, Whitcher JP, Margolis TP. Spectrum of eye disease caused by methicillin-resistant Staphylococcus aureus. Am J Ophthalmol. 2007 Aug; 144(2):313-5.
  9. Margolis TP, Imai Y, Yang L, Vallas V, Krause PR. Herpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts. J Virol. 2007 Feb; 81(4):1872-8.
  10. Prabriputaloong T, Margolis TP, Lietman TM, Wong IG, Mather R, Gritz DC. Atopic disease and herpes simplex eye disease: a population-based case-control study. Am J Ophthalmol. 2006 Nov; 142(5):745-9.
  11. Stone DU, Char DH, Crawford JB, Margolis TP, Van Gelder RN, Strauss EC. Metaplastic squamous epithelial downgrowth after clear corneal cataract surgery. Am J Ophthalmol. 2006 Oct; 142(4):695-7.
  12. Gussow AM, Giordani NV, Tran RK, Imai Y, Kwiatkowski DL, Rall GF, Margolis TP, Bloom DC. Tissue-specific splicing of the herpes simplex virus type 1 latency-associated transcript (LAT) intron in LAT transgenic mice. J Virol. 2006 Oct; 80(19):9414-23.
  13. Margolis TP, Whitcher JP. Fusarium--A new culprit in the contact lens case. JAMA. 2006 Aug 23; 296(8):985-7.
  14. Nikulina K, Bodeker M, Warren J, Matthews P, Margolis TP. A novel Krüppel related factor consisting of only a KRAB domain is expressed in the murine trigeminal ganglion. Biochem Biophys Res Commun. 2006 Sep 29; 348(3):839-49.
  15. Seitzman GD, Strauss EC, Margolis TP. "Steel wool keratopathy": a clinical sign of chronic inflammation. Cornea. 2006 Jul; 25(6):742-4.
  16. Halford WP, Weisend C, Grace J, Soboleski M, Carr DJ, Balliet JW, Imai Y, Margolis TP, Gebhardt BM. ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency. Virol J. 2006 Jun 09; 3:44.
  17. Seitzman GD, Cevallos V, Margolis TP. Rose bengal and lissamine green inhibit detection of herpes simplex virus by PCR. Am J Ophthalmol. 2006 Apr; 141(4):756-8.
  18. Paskowitz DM, Greenberg KP, Yasumura D, Grimm D, Yang H, Duncan JL, Kay MA, Lavail MM, Flannery JG, Vollrath D. Rapid and stable knockdown of an endogenous gene in retinal pigment epithelium. Hum Gene Ther. 2007 Oct; 18(10):871-80.
  19. Saidel MA, Berreen J, Margolis TP. Cytomegalovirus retinitis after intravitreous triamcinolone in an immunocompetent patient. Am J Ophthalmol. 2005 Dec; 140(6):1141-3.
  20. Magone MT, Nasser RE, Cevallos AV, Margolis TP. Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing. Am J Ophthalmol. 2005 Jun; 139(6):1135-6.
  21. McLeod SD, Mather R, Hwang DG, Margolis TP. Uveitis-associated flap edema and lamellar interface fluid collection after LASIK. Am J Ophthalmol. 2005 Jun; 139(6):1137-9.
  22. Strauss EC, Aldave AJ, Spencer WH, Branco BC, Barsness DA, Calman AF, Margolis TP. Management of prominent iris vascular tufts causing recurrent spontaneous hyphema. Cornea. 2005 Mar; 24(2):224-6.
  23. Margolis TP, Lietman T, Strauss E. Infectious agents and ARMD: a connection? Am J Ophthalmol. 2004 Sep; 138(3):468-70.
  24. Jeng BH, Whitcher JP, Margolis TP. Pseudogerontoxon. Clin Exp Ophthalmol. 2004 Aug; 32(4):433-4.
  25. Varaprasathan G, Miller K, Lietman T, Whitcher JP, Cevallos V, Okumoto M, Margolis TP, Yinghui M, Cunningham ET. Trends in the etiology of infectious corneal ulcers at the F. I. Proctor Foundation. Cornea. 2004 May; 23(4):360-4.