Ruth Greenblatt, MD

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Ruth Greenblatt, MD

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Emeritus CFAR Mentor
Professor Emeritus, School of Pharmacy
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Biography

I am an Infectious Diseases trained Internist based in the Department of Clinical Pharmacy, in the UCSF School of Pharmacy. My research is focused on HIV infection in women, particularly the effects of gonadal aging and pharmacology. My group developed novel methods for assessing exposure to antiretroviral drugs using small samples of hair. I am one of three Principal Investigators of the Northern California site of the Women's Interagency HIV Study, which is the largest NIH-supported study of HIV among women, and one of the most diverse NIH-funded cohort studies. I am the founder of the UCSF WIHS consortium and the UCSF Women's HIV Practice. Within the School of Pharmacy, I am the Vice Chair for Research of the Department of Clinical Pharmacy (Lisa Kroon, PharmD is the Chair). I previously chaired the UCSF School of Pharmacy Faculty Council, and I am currently Vice Chair of the UCSF Academic Senate. With the School of Pharmacy Dean, B. Joseph Guglielmo, and Monica Gandhi, MD, I co-lead the UCSF Bridging Interdisciplinary Research Careers in Women's Health K-12 program for early career clinical scientists focused on Women's Health. I co-founded, with James Kahn, the UCSF/Gladstone Center for AIDS Research Mentoring Program.
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  1. Massad LS, Evans CT, Wilson TE, Golub ET, Goparaju L, Howard A, Greenblatt RM, Weber K, Schilder K. Impact of menopause on condom use by HIV-seropositive and comparison seronegative women. J Acquir Immune Defic Syndr. 2008 Mar 01; 47(3):401-2.
    http://www.ncbi.nlm.nih.gov/pubmed/18398976
  2. Kahn J, Des Jarlais CD, Dobkin L, Barrs SF, Greenblatt RM. Mentoring the next generation of HIV prevention researchers: a model mentoring program at the University of California San Francisco and Gladstone Institute of Immunology and Virology Center for AIDS research. J Acquir Immune Defic Syndr. 2008 Mar 01; 47 Suppl 1:S5-9.
    http://www.ncbi.nlm.nih.gov/pubmed/18301135
  3. Nowicki MJ, Vigen C, Mack WJ, Seaberg E, Landay A, Anastos K, Young M, Minkoff H, Greenblatt R, Levine AM. Association of cells with natural killer (NK) and NKT immunophenotype with incident cancers in HIV-infected women. AIDS Res Hum Retroviruses. 2008 Feb; 24(2):163-8.
    http://www.ncbi.nlm.nih.gov/pubmed/18240964
  4. Kapadia F, Vlahov D, Wu Y, Cohen MH, Greenblatt RM, Howard AA, Cook JA, Goparaju L, Golub E, Richardson J, Wilson TE. Impact of drug abuse treatment modalities on adherence to ART/HAART among a cohort of HIV seropositive women. Am J Drug Alcohol Abuse. 2008; 34(2):161-70.
    http://www.ncbi.nlm.nih.gov/pubmed/18293232
  5. Seifer DB, Golub ET, Lambert-Messerlian G, Springer G, Holman S, Moxley M, Cejtin H, Nathwani N, Anastos K, Minkoff H, Greenblatt RM. Biologic markers of ovarian reserve and reproductive aging: application in a cohort study of HIV infection in women. Fertil Steril. 2007 Dec; 88(6):1645-52.
    http://www.ncbi.nlm.nih.gov/pubmed/17418155
  6. Nowicki MJ, Karim R, Mack WJ, Minkoff H, Anastos K, Cohen M, Greenblatt RM, Young MA, Gange SJ, Levine AM. Correlates of CD4+ and CD8+ lymphocyte counts in high-risk immunodeficiency virus (HIV)-seronegative women enrolled in the women's interagency HIV study (WIHS). Hum Immunol. 2007 May; 68(5):342-9.
    http://www.ncbi.nlm.nih.gov/pubmed/17462501
  7. Neely MN, Benning L, Xu J, Strickler HD, Greenblatt RM, Minkoff H, Young M, Bremer J, Levine AM, Kovacs A. Cervical shedding of HIV-1 RNA among women with low levels of viremia while receiving highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2007 Jan 01; 44(1):38-42.
    http://www.ncbi.nlm.nih.gov/pubmed/17106279
  8. Watts DH, Springer G, Minkoff H, Hillier SL, Jacobson L, Moxley M, Justman J, Cejtin H, O'Connell C, Greenblatt RM. The occurrence of vaginal infections among HIV-infected and high-risk HIV-uninfected women: longitudinal findings of the women's interagency HIV study. J Acquir Immune Defic Syndr. 2006 Oct 01; 43(2):161-8.
    http://www.ncbi.nlm.nih.gov/pubmed/16951644
  9. French AL, Evans CT, Anastos K, Greenblatt RM, Hershow R, Huebner R, Augenbraun M, Young M, Lopez-Gatell H, Passaro DJ. Incidence of tuberculin skin test conversion among HIV-infected and -uninfected women: results of a 6-year study. J Acquir Immune Defic Syndr. 2006 Aug 15; 42(5):592-6.
    http://www.ncbi.nlm.nih.gov/pubmed/16837868
  10. Massad LS, Evans CT, Minkoff H, Watts DH, Greenblatt RM, Levine AM, Anastos K, Young M, Seifer DB, Golub E, Cohen M. Effects of HIV infection and its treatment on self-reported menstrual abnormalities in women. J Womens Health (Larchmt). 2006 Jun; 15(5):591-8.
    http://www.ncbi.nlm.nih.gov/pubmed/16796486
  11. Gordeuk VR, Onojobi G, Schneider MF, Dawkins FW, Delapenha R, Voloshin Y, von Wyl V, Bacon M, Minkoff H, Levine A, Cohen M, Greenblatt RM. The association of serum ferritin and transferrin receptor concentrations with mortality in women with human immunodeficiency virus infection. Haematologica. 2006 Jun; 91(6):739-43.
    http://www.ncbi.nlm.nih.gov/pubmed/16704960
  12. Ameli N, Bacchetti P, Morrow RA, Hessol NA, Wilkin T, Young M, Cohen M, Minkoff H, Gange SJ, Greenblatt RM. Herpes simplex virus infection in women in the WIHS: epidemiology and effect of antiretroviral therapy on clinical manifestations. AIDS. 2006 Apr 24; 20(7):1051-8.
    http://www.ncbi.nlm.nih.gov/pubmed/16603858
  13. Gange SJ, Schneider MF, Grant RM, Liegler T, French A, Young M, Anastos K, Wilson TE, Ponath C, Greenblatt R. Genotypic resistance and immunologic outcomes among HIV-1-infected women with viral failure. J Acquir Immune Defic Syndr. 2006 Jan 01; 41(1):68-74.
    http://www.ncbi.nlm.nih.gov/pubmed/16340476
  14. Napolitano LA, Burt TD, Bacchetti P, Barrón Y, French AL, Kovacs A, Anastos K, Young M, McCune JM, Greenblatt RM. Increased circulating interleukin-7 levels in HIV-1-infected women. J Acquir Immune Defic Syndr. 2005 Dec 15; 40(5):581-4.
    http://www.ncbi.nlm.nih.gov/pubmed/16284535
  15. Latka MH, Wilson TE, Cook JA, Bacon MC, Richardson JL, Sohler N, Cohen MH, Greenblatt RM, Andreopoulis E, Vlahov D. Impact of drug treatment on subsequent sexual risk behavior in a multisite cohort of drug-using women: a report from the Women's Interagency HIV Study. J Subst Abuse Treat. 2005 Dec; 29(4):329-37.
    http://www.ncbi.nlm.nih.gov/pubmed/16311186
  16. Schneider MF, Gange SJ, Williams CM, Anastos K, Greenblatt RM, Kingsley L, Detels R, Muñoz A. Patterns of the hazard of death after AIDS through the evolution of antiretroviral therapy: 1984-2004. AIDS. 2005 Nov 18; 19(17):2009-18.
    http://www.ncbi.nlm.nih.gov/pubmed/16260908
  17. Gandhi M, Ameli N, Bacchetti P, Sharp GB, French AL, Young M, Gange SJ, Anastos K, Holman S, Levine A, Greenblatt RM. Eligibility criteria for HIV clinical trials and generalizability of results: the gap between published reports and study protocols. AIDS. 2005 Nov 04; 19(16):1885-96.
    http://www.ncbi.nlm.nih.gov/pubmed/16227797
  18. Shiboski CH, Cohen M, Weber K, Shansky A, Malvin K, Greenblatt RM. Factors associated with use of dental services among HIV-infected and high-risk uninfected women. J Am Dent Assoc. 2005 Sep; 136(9):1242-55.
    http://www.ncbi.nlm.nih.gov/pubmed/16196229
  19. Anastos K, Schneider MF, Gange SJ, Minkoff H, Greenblatt RM, Feldman J, Levine A, Delapenha R, Cohen M. The association of race, sociodemographic, and behavioral characteristics with response to highly active antiretroviral therapy in women. J Acquir Immune Defic Syndr. 2005 Aug 15; 39(5):537-44.
    http://www.ncbi.nlm.nih.gov/pubmed/16044004
  20. Kapadia F, Cook JA, Cohen MH, Sohler N, Kovacs A, Greenblatt RM, Choudhary I, Vlahov D. The relationship between non-injection drug use behaviors on progression to AIDS and death in a cohort of HIV seropositive women in the era of highly active antiretroviral therapy use. Addiction. 2005 Jul; 100(7):990-1002.
    http://www.ncbi.nlm.nih.gov/pubmed/15955015
  21. Chu JH, Gange SJ, Anastos K, Minkoff H, Cejtin H, Bacon M, Levine A, Greenblatt RM. Hormonal contraceptive use and the effectiveness of highly active antiretroviral therapy. Am J Epidemiol. 2005 May 01; 161(9):881-90.
    http://www.ncbi.nlm.nih.gov/pubmed/15840621
  22. Ahdieh-Grant L, Tarwater PM, Schneider MF, Anastos K, Cohen M, Khalsa A, Minkoff H, Young M, Greenblatt RM. Factors and temporal trends associated with highly active antiretroviral therapy discontinuation in the Women's Interagency HIV Study. J Acquir Immune Defic Syndr. 2005 Apr 01; 38(4):500-3.
    http://www.ncbi.nlm.nih.gov/pubmed/15764968
  23. Kobayashi A, Greenblatt RM, Anastos K, Minkoff H, Massad LS, Young M, Levine AM, Darragh TM, Weinberg V, Smith-McCune KK. Functional attributes of mucosal immunity in cervical intraepithelial neoplasia and effects of HIV infection. Cancer Res. 2004 Sep 15; 64(18):6766-74.
    http://www.ncbi.nlm.nih.gov/pubmed/15374995
  24. Philpott S, Burger H, Tarwater PM, Lu M, Gange SJ, Anastos K, Cohen M, Greenblatt RM, Kovacs A, Minkoff H, Young M, Miotti P, Dupuis M, Weiser B. CCR2 genotype and disease progression in a treated population of HIV type 1-infected women. Clin Infect Dis. 2004 Sep 15; 39(6):861-5.
    http://www.ncbi.nlm.nih.gov/pubmed/15472820
  25. Barrón Y, Cole SR, Greenblatt RM, Cohen MH, Anastos K, DeHovitz JA, Delapenha R, Gange SJ. Effect of discontinuing antiretroviral therapy on survival of women initiated on highly active antiretroviral therapy. AIDS. 2004 Jul 23; 18(11):1579-84.
    http://www.ncbi.nlm.nih.gov/pubmed/15238776