Adithya Cattamanchi, MD, MAS

CTSI Profile Photo

Adithya Cattamanchi, MD, MAS

User Profile Name
Professor, School of Medicine
CTSI Profile Title
User Profile Email
Visit CTSI Profile

Biography

My research is focused on two thematic areas: 1) Development and evaluation of tuberculosis (TB) diagnostics and 2) Implementation and dissemination of evidence-based preventative, diagnostic, and treatment interventions for TB. I have considerable experience with the evaluation of TB diagnostics in low-income countries, including studying the impact of new diagnostics on patient- and public health-important outcomes. I have served on several World Health Organization (WHO) Expert Group panels to develop new policies related to TB diagnostics and serve as a faculty member for the Advanced Tuberculosis Diagnostics Research workshop sponsored by the WHO Stop TB Partnership. I have initiated a number of collaborations with engineers in industry and academia to develop and evaluate new diagnostic platforms for TB including: 1) mobile phone-based microscopy; 2) mobile phone-based molecular diagnostic platforms; and 3) single-particle aerosol mass spectrometry. We are currently evaluating the mobile phone-based microscopy platform and health centers in Hanoi, Vietnam in a demonstration project funded by the TB REACH initiative.

In addition to research on TB diagnostics, I have developed an active research agenda related to implementation science. I helped establish a platform for monitoring the quality of TB care at 6 rural health centers in Uganda (Uganda Tuberculosis Surveillance Project). My current work, supported through an NIH/NIAID R21 in Implementation and Dissemination Science, is focused on improving the quality of TB suspect evaluation at these health centers.

User Profile Bio

Displaying 76 - 100 of 202

  1. Kendall EA, Kamoga C, Kitonsa PJ, Nalutaaya A, Salvatore PP, Robsky K, Nakasolya O, Mukiibi J, Isooba D, Cattamanchi A, Kato-Maeda M, Katamba A, Dowdy DW. Empiric treatment of pulmonary TB in the Xpert era: Correspondence of sputum culture, Xpert MTB/RIF, and clinical diagnoses. PLoS One. 2019; 14(7):e0220251.
    http://www.ncbi.nlm.nih.gov/pubmed/31720434
  2. Rajan JV, Semitala FC, Mehta T, Seielstad M, Montalvo L, Andama A, Asege L, Nakaye M, Katende J, Mwebe S, Kamya MR, Yoon C, Cattamanchi A. A Novel, 5-Transcript, Whole-blood Gene-expression Signature for Tuberculosis Screening Among People Living With Human Immunodeficiency Virus. Clin Infect Dis. 2018 Nov 20.
    http://www.ncbi.nlm.nih.gov/pubmed/30462176
  3. Rajan JV, Semitala FC, Mehta T, Seielstad M, Montalvo L, Andama A, Asege L, Nakaye M, Katende J, Mwebe S, Kamya MR, Yoon C, Cattamanchi A. A Novel, 5-Transcript, Whole-blood Gene-expression Signature for Tuberculosis Screening Among People Living With Human Immunodeficiency Virus. Clin Infect Dis. 2019 06 18; 69(1):77-83.
    http://www.ncbi.nlm.nih.gov/pubmed/31151255
  4. Wobudeya E, Jaganath D, Sekadde MP, Nsangi B, Haq H, Cattamanchi A. Outcomes of empiric treatment for pediatric tuberculosis, Kampala, Uganda, 2010-2015. BMC Public Health. 2019 Apr 29; 19(1):446.
    http://www.ncbi.nlm.nih.gov/pubmed/31035984
  5. Wobudeya E, Jaganath D, Sekadde MP, Nsangi B, Haq H, Cattamanchi A. Outcomes of empiric treatment for pediatric tuberculosis, Kampala, Uganda, 2010-2015. BMC Public Health. 2019 Apr 29; 19(1):446.
    http://www.ncbi.nlm.nih.gov/pubmed/31720425
  6. Goodell AJ, Shete PB, Vreman R, McCabe D, Porco TC, Barry PM, Flood J, Marks SM, Hill A, Cattamanchi A, Kahn JG. Outlook for tuberculosis elimination in California: An individual-based stochastic model. PLoS One. 2019; 14(4):e0214532.
    http://www.ncbi.nlm.nih.gov/pubmed/30964878
  7. Jaganath D, Wobudeya E, Sekadde MP, Nsangi B, Haq H, Cattamanchi A. Seasonality of childhood tuberculosis cases in Kampala, Uganda, 2010-2015. PLoS One. 2019; 14(4):e0214555.
    http://www.ncbi.nlm.nih.gov/pubmed/30964908
  8. Chaisson LH, Semitala FC, Asege L, Mwebe S, Katende J, Nakaye M, Andama AO, Marquez C, Atuhumuza E, Kamya M, Cattamanchi A, Yoon C. Point-of-care C-reactive protein and risk of early mortality among adults initiating antiretroviral therapy. AIDS. 2019 Jan 14.
    http://www.ncbi.nlm.nih.gov/pubmed/30649057
  9. Chaisson LH, Semitala FC, Asege L, Mwebe S, Katende J, Nakaye M, Andama AO, Marquez C, Atuhumuza E, Kamya M, Cattamanchi A, Yoon C. Point-of-care C-reactive protein and risk of early mortality among adults initiating antiretroviral therapy. AIDS. 2019 04 01; 33(5):895-902.
    http://www.ncbi.nlm.nih.gov/pubmed/30913250
  10. Reid MJA, Arinaminpathy N, Bloom A, Bloom BR, Boehme C, Chaisson R, Chin DP, Churchyard G, Cox H, Ditiu L, Dybul M, Farrar J, Fauci AS, Fekadu E, Fujiwara PI, Hallett TB, Hanson CL, Harrington M, Herbert N, Hopewell PC, Ikeda C, Jamison DT, Khan AJ, Koek I, Krishnan N, Motsoaledi A, Pai M, Raviglione MC, Sharman A, Small PM, Swaminathan S, Temesgen Z, Vassall A, Venkatesan N, van Weezenbeek K, Yamey G, Agins BD, Alexandru S, Andrews JR, Beyeler N, Bivol S, Brigden G, Cattamanchi A, Cazabon D, Crudu V, Daftary A, Dewan P, Doepel LK, Eisinger RW, Fan V, Fewer S, Furin J, Goldhaber-Fiebert JD, Gomez GB, Graham SM, Gupta D, Kamene M, Khaparde S, Mailu EW, Masini EO, McHugh L, Mitchell E, Moon S, Osberg M, Pande T, Prince L, Rade K, Rao R, Remme M, Seddon JA, Selwyn C, Shete P, Sachdeva KS, Stallworthy G, Vesga JF, Vilc V, Goosby EP. Building a tuberculosis-free world: The Lancet Commission on tuberculosis. Lancet. 2019 Mar 20.
    http://www.ncbi.nlm.nih.gov/pubmed/30904263
  11. Reid MJA, Arinaminpathy N, Bloom A, Bloom BR, Boehme C, Chaisson R, Chin DP, Churchyard G, Cox H, Ditiu L, Dybul M, Farrar J, Fauci AS, Fekadu E, Fujiwara PI, Hallett TB, Hanson CL, Harrington M, Herbert N, Hopewell PC, Ikeda C, Jamison DT, Khan AJ, Koek I, Krishnan N, Motsoaledi A, Pai M, Raviglione MC, Sharman A, Small PM, Swaminathan S, Temesgen Z, Vassall A, Venkatesan N, van Weezenbeek K, Yamey G, Agins BD, Alexandru S, Andrews JR, Beyeler N, Bivol S, Brigden G, Cattamanchi A, Cazabon D, Crudu V, Daftary A, Dewan P, Doepel LK, Eisinger RW, Fan V, Fewer S, Furin J, Goldhaber-Fiebert JD, Gomez GB, Graham SM, Gupta D, Kamene M, Khaparde S, Mailu EW, Masini EO, McHugh L, Mitchell E, Moon S, Osberg M, Pande T, Prince L, Rade K, Rao R, Remme M, Seddon JA, Selwyn C, Shete P, Sachdeva KS, Stallworthy G, Vesga JF, Vilc V, Goosby EP. Building a tuberculosis-free world: The Lancet Commission on tuberculosis. Lancet. 2019 Mar 30; 393(10178):1331-1384.
    http://www.ncbi.nlm.nih.gov/pubmed/30890135
  12. Keshavjee S, Amanullah F, Cattamanchi A, Chaisson R, Dobos KM, Fox GJ, Gendelman HE, Gordon R, Hesseling A, Hoi LV, Kampmann B, Kana B, Khuller G, Lewinsohn DM, Lewinsohn DA, Lin PL, Lu LL, Maartens G, Owen A, Protopopova M, Rengarajan J, Rubin E, Salgame P, Schurr E, Seddon JA, Swindells S, Tobin DM, Udwadia Z, Walzl G, Srinivasan S, Rustomjee R, Nahid P. Moving Toward Tuberculosis Elimination: Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection. Am J Respir Crit Care Med. 2018 Oct 18.
    http://www.ncbi.nlm.nih.gov/pubmed/30335466
  13. Yoon C, Semitala FC, Cattamanchi A. Reply to: Implications of TB Sputum Culture Test Sensitivity on Accuracy of Other Diagnostic Modalities. Am J Respir Crit Care Med. 2018 Dec 11.
    http://www.ncbi.nlm.nih.gov/pubmed/30525900
  14. Yoon C, Semitala FC, Asege L, Katende J, Mwebe S, Andama AO, Atuhumuza E, Nakaye M, Armstrong DT, Dowdy DW, McCulloch CE, Kamya M, Cattamanchi A. Yield and Efficiency of Novel Intensified Tuberculosis Case-Finding Algorithms for People Living with HIV. Am J Respir Crit Care Med. 2018 Sep 07.
    http://www.ncbi.nlm.nih.gov/pubmed/30192649
  15. Yoon C, Semitala FC, Asege L, Katende J, Mwebe S, Andama AO, Atuhumuza E, Nakaye M, Armstrong DT, Dowdy DW, McCulloch CE, Kamya M, Cattamanchi A. Yield and Efficiency of Novel Intensified Tuberculosis Case-Finding Algorithms for People Living with HIV. Am J Respir Crit Care Med. 2019 03 01; 199(5):643-650.
    http://www.ncbi.nlm.nih.gov/pubmed/31754624
  16. S. M. Nyenhuis, N. Shah, J. Ma, D. X. Marquez, J. Wilbur, A. Cattamanchi, L. K. Sharp. Identifying barriers to physical activity among African American women with asthma. Cogent Medicine. 2019 Feb 26; 6(1).
  17. Andrew D. Kerkhoff, Adithya Cattamanchi. Diagnosis of HIV-Associated Tuberculosis. . 2019 Jan 1; 127-159.
  18. Eleanor A. Ochodo, Nelson Kalema, Samuel Schumacher, Karen Steingart, Taryn Young, Susan Mallett, Jon Deeks, Frank Cobelens, Patrick M. Bossuyt, Mark P. Nicol, Adithya Cattamanchi. Variation in the observed effect of Xpert MTB/RIF testing for tuberculosis on mortality: A systematic review and analysis of trial design considerations. Wellcome Open Research. 2019 Jan 1; 4:173.
  19. Farr K, Ravindran R, Strnad L, Chang E, Chaisson LH, Yoon C, Worodria W, Andama A, Ayakaka I, Bbosa Nalwanga P, Byanyima P, Kalema N, Kaswabuli S, Katagira W, Aman KD, Musisi E, Tumwine NW, Sanyu I, Ssebunya R, Davis JL, Huang L, Khan IH, Cattamanchi A. Diagnostic performance of blood inflammatory markers for tuberculosis screening in people living with HIV. PLoS One. 2018; 13(10):e0206119.
    http://www.ncbi.nlm.nih.gov/pubmed/30352099
  20. Siddharthan T, Pollard SL, Quaderi SA, Mirelman AJ, Cárdenas MK, Kirenga B, Rykiel NA, Miranda JJ, Shrestha L, Chandyo RK, Cattamanchi A, Michie S, Barber J, Checkley W, Hurst JR. Effectiveness-implementation of COPD case finding and self-management action plans in low- and middle-income countries: global excellence in COPD outcomes (GECo) study protocol. Trials. 2018 Oct 19; 19(1):571.
    http://www.ncbi.nlm.nih.gov/pubmed/30340648
  21. Andrew D. Kerkhoff, Adithya Cattamanchi. Diagnosis of HIV-Associated Tuberculosis. . 2019 Jan 1; 127-159.
    http://www.ncbi.nlm.nih.gov/pubmed/30236182
  22. Chaisson LH, Duong D, Cattamanchi A, Roemer M, Handley MA, Schillinger D, Sur M, Pham P, Lin MA, Goldman LE, Quan J, Perez S, Healy M, Higashi J, Winston L, Haller B, Luetkemeyer AF, Davis JL. Association of Rapid Molecular Testing With Duration of Respiratory Isolation for Patients With Possible Tuberculosis in a US Hospital. JAMA Intern Med. 2018 Oct 01; 178(10):1380-1388.
    http://www.ncbi.nlm.nih.gov/pubmed/30178007
  23. Farr K, Ravindran R, Strnad L, Chang E, Chaisson LH, Yoon C, Worodria W, Andama A, Ayakaka I, Bbosa Nalwanga P, Byanyima P, Kalema N, Kaswabuli S, Katagira W, Aman KD, Musisi E, Tumwine NW, Sanyu I, Ssebunya R, Davis JL, Huang L, Khan IH, Cattamanchi A. Diagnostic performance of blood inflammatory markers for tuberculosis screening in people living with HIV. PLoS One. 2018; 13(10):e0206119.
    http://www.ncbi.nlm.nih.gov/pubmed/30236188
  24. Roa MB, Tablizo FA, Morado EKD, Cunanan LF, Uy IDC, Ng KCS, Manalastas-Cantos KG, Reyes JM, Ganchua SKC, Ang CF, Kato-Maeda M, Cattamanchi A, Karaoz U, Destura RV, Lluisma AO. Whole-genome sequencing and single nucleotide polymorphisms in multidrug-resistant clinical isolates of Mycobacterium tuberculosis from the Philippines. J Glob Antimicrob Resist. 2018 Dec; 15:239-245.
    http://www.ncbi.nlm.nih.gov/pubmed/30130640
  25. Robert Blount, Payam Nahid, Adithya Cattamanchi. Tuberculosis. Emergency Management of Infectious Diseases. 2018 Aug 9; 308-318.