Establishing the HIV reservoir: HIV-susceptible cells and the signals that recruit them

Award Recipient - Excellence in Basic Science

Thomas Packard is a postdoctoral scholar in Warner Greene’s laboratory at the Gladstone Institute of Virology and Immunology. My research focuses on HIV pathogenesis mechanisms: specifically, the molecular pathways that are triggered during HIV infection, and how these pathways shape the immune response. I am fascinated by innate immune sensing, as these signals are critical to driving protective and pathologic immune responses. By investigating the molecular pathways involved, we can exploit these interactions to modulate the immune response, enhancing host defense while inhibiting inflammation or autoimmunity. I received my PhD in Immunology from University of Colorado SOM; where he studied B cells in autoimmunity, as well as innate immune activation driving inflammation. My current research focuses on the role of the host innate response in establishment of the latent HIV reservoir.