Lynn Pulliam, MS, PhD

Photo of Lynn Pulliam, MS, PhD

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(415) 221-4810

4150 Clement St, Blg 2, Rm 259
San Francisco, CA 94121

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  • Professor, UCSF School of Medicine
  • Member, CFAR Scientific Council

Biography

Dr. Pulliam is Professor of Laboratory Medicine and Medicine at UCSF. Her research interests are in HIV-associated cognitive impairment, neuroinflammation and chronic monocyte activation. She is former President and continuing Board of Directors Member of the Society for Neurovirology as well as a member of several journal Editorial Boards. Dr. Pulliam is Director of Microbiology at the San Francisco Veterans Affairs Medical Center where she teaches microbiology to Infectious Disease and Laboratory Medicine residents and fellows.

Displaying 1 - 39 of 39

  1. Tang N, Sun B, Gupta A, Rempel H, Pulliam L. Monocyte exosomes induce adhesion molecules and cytokines via activation of NF-?B in endothelial cells. FASEB J. 2016 Sep; 30(9):3097-106. View on Pubmed
  2. Goetzl EJ, Goetzl L, Karliner JS, Tang N, Pulliam L. Human plasma platelet-derived exosomes: effects of aspirin. FASEB J. 2016 May; 30(5):2058-63. View on Pubmed
  3. Pulliam L, Gupta A. Modulation of cellular function through immune-activated exosomes. DNA Cell Biol. 2015 Jul; 34(7):459-63. View on Pubmed
  4. Pulliam L, Calosing C, Sun B, Grunfeld C, Rempel H. Monocyte activation from interferon-a in HIV infection increases acetylated LDL uptake and ROS production. J Interferon Cytokine Res. 2014 Oct; 34(10):822-8. View on Pubmed
  5. Pulliam L. Cognitive consequences of a sustained monocyte type 1 IFN response in HIV-1 infection. Curr HIV Res. 2014; 12(2):77-84. View on Pubmed
  6. Rempel H, Sun B, Calosing C, Abadjian L, Monto A, Pulliam L. Monocyte activation in HIV/HCV coinfection correlates with cognitive impairment. PLoS One. 2013; 8(2):e55776. View on Pubmed
  7. Sun B, Abadjian L, Rempel H, Monto A, Pulliam L. Differential cognitive impairment in HCV coinfected men with controlled HIV compared to HCV monoinfection. J Acquir Immune Defic Syndr. 2013 Feb 1; 62(2):190-6. View on Pubmed
  8. Joseph J, Achim CL, Boivin MJ, Brew BJ, Clifford DB, Colosi DA, Ellis RJ, Heaton RK, Gallo-Diop A, Grant I, Kanmogne GD, Kumar M, Letendre S, Marcotte TD, Nath A, Pardo CA, Paul RH, Pulliam L, Robertson K, Royal W, Sacktor N, Sithinamsuwan P, Smith DM, Valcour V, Wigdahl B, Wood C. Global NeuroAIDS roundtable. J Neurovirol. 2013 Feb; 19(1):1-9. View on Pubmed
  9. Wang Q, Na B, Ou JH, Pulliam L, Yen TS. Hepatitis B virus alters the antioxidant system in transgenic mice and sensitizes hepatocytes to Fas signaling. PLoS One. 2012; 7(5):e36818. View on Pubmed
  10. Pulliam L, Rempel H, Sun B, Abadjian L, Calosing C, Meyerhoff DJ. A peripheral monocyte interferon phenotype in HIV infection correlates with a decrease in magnetic resonance spectroscopy metabolite concentrations. AIDS. 2011 Sep 10; 25(14):1721-6. View on Pubmed
  11. O'Donovan A, Sun B, Cole S, Rempel H, Lenoci M, Pulliam L, Neylan T. Transcriptional control of monocyte gene expression in post-traumatic stress disorder. Dis Markers. 2011; 30(2-3):123-32. View on Pubmed
  12. Neylan TC, Sun B, Rempel H, Ross J, Lenoci M, O'Donovan A, Pulliam L. Suppressed monocyte gene expression profile in men versus women with PTSD. Brain Behav Immun. 2011 Mar; 25(3):524-31. View on Pubmed
  13. Rempel H, Sun B, Calosing C, Pillai SK, Pulliam L. Interferon-alpha drives monocyte gene expression in chronic unsuppressed HIV-1 infection. AIDS. 2010 Jun 19; 24(10):1415-23. View on Pubmed
  14. Sun B, Abadjian L, Rempel H, Calosing C, Rothlind J, Pulliam L. Peripheral biomarkers do not correlate with cognitive impairment in highly active antiretroviral therapy-treated subjects with human immunodeficiency virus type 1 infection. J Neurovirol. 2010 Mar; 16(2):115-24. View on Pubmed
  15. Hans Rempel, Bing Sun, Cyrus Calosing, Satish Pillai, Lynn Pulliam. Interferon alpha drives monocyte gene expression in chronic unsuppressed HIV-i1 infection. 2010; 24:1415-1423. View on Pubmed
  16. Pulliam L. HIV regulation of amyloid beta production. J Neuroimmune Pharmacol. 2009 Jun; 4(2):213-7. View on Pubmed
  17. Rempel H, Calosing C, Sun B, Pulliam L. Sialoadhesin expressed on IFN-induced monocytes binds HIV-1 and enhances infectivity. PLoS One. 2008; 3(4):e1967. View on Pubmed
  18. Price RW, Epstein LG, Becker JT, Cinque P, Gisslen M, Pulliam L, McArthur JC. Biomarkers of HIV-1 CNS infection and injury. Neurology. 2007 Oct 30; 69(18):1781-8. View on Pubmed
  19. Rempel HC, Pulliam L. HIV-1 Tat inhibits neprilysin and elevates amyloid beta. AIDS. 2005 Jan 28; 19(2):127-35. View on Pubmed
  20. Pulliam L, Sun B, Rempel H. Invasive chronic inflammatory monocyte phenotype in subjects with high HIV-1 viral load. J Neuroimmunol. 2004 Dec; 157(1-2):93-8. View on Pubmed
  21. Sun B, Rempel HC, Pulliam L. Loss of macrophage-secreted lysozyme in HIV-1-associated dementia detected by SELDI-TOF mass spectrometry. AIDS. 2004 Apr 30; 18(7):1009-12. View on Pubmed
  22. Kusdra L, McGuire D, Pulliam L. Changes in monocyte/macrophage neurotoxicity in the era of HAART: implications for HIV-associated dementia. AIDS. 2002 Jan 4; 16(1):31-8. View on Pubmed
  23. Rempel H, Kusdra L, Pulliam L. Interleukin-1beta up-regulates expression of neurofilament light in human neuronal cells. J Neurochem. 2001 Aug; 78(3):640-5. View on Pubmed
  24. Pulliam L, Irwin I, Kusdra L, Rempel H, Flitter WD, Garland WA. CPI-1189 attenuates effects of suspected neurotoxins associated with AIDS dementia: a possible role for ERK activation. Brain Res. 2001 Mar 2; 893(1-2):95-103. View on Pubmed
  25. Kusdra L, Rempel H, Yaffe K, Pulliam L. Elevation of CD69+ monocyte/macrophages in patients with Alzheimer's disease. Immunobiology. 2000 May; 202(1):26-33. View on Pubmed
  26. Pulliam L, Zhou M, Stubblebine M, Bitler CM. Differential modulation of cell death proteins in human brain cells by tumor necrosis factor alpha and platelet activating factor. J Neurosci Res. 1998 Nov 15; 54(4):530-8. View on Pubmed
  27. Pulliam L, Stubblebine M, Hyun W. Quantification of neurotoxicity and identification of cellular subsets in a three-dimensional brain model. Cytometry. 1998 May 1; 32(1):66-9. View on Pubmed
  28. Pulliam L, Gascon R, Stubblebine M, McGuire D, McGrath MS. Unique monocyte subset in patients with AIDS dementia. Lancet. 1997 Mar 8; 349(9053):692-5. View on Pubmed
  29. Pulliam L, Clarke JA, McGrath MS, Moore D, McGuire D. Monokine products as predictors of AIDS dementia. AIDS. 1996 Nov; 10(13):1495-500. View on Pubmed
  30. Pulliam L, Moore D, West DC. Human cytomegalovirus induces IL-6 and TNF alpha from macrophages and microglial cells: possible role in neurotoxicity. J Neurovirol. 1995 Jun; 1(2):219-27. View on Pubmed
  31. Yeung MC, Pulliam L, Lau AS. The HIV envelope protein gp120 is toxic to human brain-cell cultures through the induction of interleukin-6 and tumor necrosis factor-alpha. AIDS. 1995 Feb; 9(2):137-43. View on Pubmed
  32. Pulliam L, Clarke JA, McGuire D, McGrath MS. Investigation of HIV-infected macrophage neurotoxin production from patients with AIDS dementia. Adv Neuroimmunol. 1994; 4(3):195-8. View on Pubmed
  33. Pulliam L, West D, Haigwood N, Swanson RA. HIV-1 envelope gp120 alters astrocytes in human brain cultures. AIDS Res Hum Retroviruses. 1993 May; 9(5):439-44. View on Pubmed
  34. Hughes-Fulford M, McGrath MS, Hanks D, Erickson S, Pulliam L. Effects of dimethyl prostaglandin A1 on herpes simplex virus and human immunodeficiency virus replication. Antimicrob Agents Chemother. 1992 Oct; 36(10):2253-8. View on Pubmed
  35. Pulliam L, Herndier BG, McGrath MS. Purified trichosanthin (GLQ223) exacerbation of indirect HIV-associated neurotoxicity in vitro. AIDS. 1991 Oct; 5(10):1237-42. View on Pubmed
  36. Pulliam L. Cytomegalovirus preferentially infects a monocyte derived macrophage/microglial cell in human brain cultures: neuropathology differs between strains. J Neuropathol Exp Neurol. 1991 Jul; 50(4):432-40. View on Pubmed
  37. Pulliam L, Herndier BG, Tang NM, McGrath MS. Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains. J Clin Invest. 1991 Feb; 87(2):503-12. View on Pubmed
  38. Cregan P, Yamamoto A, Lum A, VanDerHeide T, MacDonald M, Pulliam L. Comparison of four methods for rapid detection of Pneumocystis carinii in respiratory specimens. J Clin Microbiol. 1990 Nov; 28(11):2432-6.
  39. Pulliam L, Berens ME, Rosenblum ML. A normal human brain cell aggregate model for neurobiological studies. J Neurosci Res. 1988 Oct-Dec; 21(2-4):521-30.