Francis Szoka, PhD

Email Francis
(415) 476-3895

513 Parnassus Ave
San Francisco, CA 94143

Visit CTSI Profile

Email Francis
(415) 476-3895

513 Parnassus Ave
San Francisco, CA 94143

Visit CTSI Profile

  • Professor, UCSF School of Pharmacy
  • Professor, UCSF School of Pharmacy

Biography

The Szoka group applies chemical, biophysical and molecular biology approaches to devise vaccine, drug and nucleic acid delivery systems to treat cancer or infectious diseases. These systems can incorporate lipids, peptides, polymers and proteins. These drug carriers are composed of lipids, polymers, peptides or proteins. His group has extensively investigated the role of lipids in membrane fusion and his designed, synthesized and studied the mechanism of fusogenic peptides. With group members, he has published over 195 manuscripts and has received 26 U.S. patents. One FDA approved drug product Amphotec™ and one biotechnology product Superfect™ have been commercialized from the patents. In addition to his University commitments, Dr. Szoka is a founder of Sequus Pharmaceuticals, Inc. owned by Johnson & Johnson and GeneMedicine, inc. now known as Valentis, Inc. Sequus introduced sterically stabilized liposomes for anti-cancer drug delivery (Doxil™).

Biography

The Szoka group applies chemical, biophysical and molecular biology approaches to devise vaccine, drug and nucleic acid delivery systems to treat cancer or infectious diseases. These systems can incorporate lipids, peptides, polymers and proteins. These drug carriers are composed of lipids, polymers, peptides or proteins. His group has extensively investigated the role of lipids in membrane fusion and his designed, synthesized and studied the mechanism of fusogenic peptides. With group members, he has published over 195 manuscripts and has received 26 U.S. patents. One FDA approved drug product Amphotec™ and one biotechnology product Superfect™ have been commercialized from the patents. In addition to his University commitments, Dr. Szoka is a founder of Sequus Pharmaceuticals, Inc. owned by Johnson & Johnson and GeneMedicine, inc. now known as Valentis, Inc. Sequus introduced sterically stabilized liposomes for anti-cancer drug delivery (Doxil™).

Displaying 1 - 394 of 394

  1. Iman M, Huang Z, Alavizadeh SH, Szoka FC, Jaafari MR. Biodistribution and In Vivo Antileishmanial Activity of 1,2-Distigmasterylhemisuccinoyl-sn-Glycero-3-Phosphocholine Liposome-Intercalated Amphotericin B. Antimicrob Agents Chemother. 2017 Sep; 61(9). View on Pubmed
  2. Kieler-Ferguson HM, Chan D, Sockolosky J, Finney L, Maxey E, Vogt S, Szoka FC. Encapsulation, controlled release, and antitumor efficacy of cisplatin delivered in liposomes composed of sterol-modified phospholipids. Eur J Pharm Sci. 2017 May 30; 103:85-93. View on Pubmed
  3. Tiffany M, Szoka FC. Co-localization of fluorescent labeled lipid nanoparticles with specifically tagged subcellular compartments by single particle tracking at low nanoparticle to cell ratios. J Drug Target. 2016 Nov; 24(9):857-864. View on Pubmed
  4. Yuan W, Kuai R, Dai Z, Yuan Y, Zheng N, Jiang W, Noble C, Hayes M, Szoka FC, Schwendeman A. Development of a Flow-Through USP-4 Apparatus Drug Release Assay to Evaluate Doxorubicin Liposomes. AAPS J. 2017 Jan; 19(1):150-160. View on Pubmed
  5. Lee S, Kivimäe S, Dolor A, Szoka FC. Macrophage-based cell therapies: The long and winding road. J Control Release. 2016 Oct 28; 240:527-540. View on Pubmed
  6. Kierstead PH, Okochi H, Venditto VJ, Chuong TC, Kivimae S, Fréchet JMJ, Szoka FC. The effect of polymer backbone chemistry on the induction of the accelerated blood clearance in polymer modified liposomes. J Control Release. 2015 Sep 10; 213:1-9. View on Pubmed
  7. Sockolosky JT, Szoka FC. The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy. Adv Drug Deliv Rev. 2015 Aug 30; 91:109-24. View on Pubmed
  8. Venditto VJ, Dolor A, Kohli A, Salentinig S, Boyd BJ, Szoka FC. Sulfated quaternary amine lipids: a new class of inverse charge zwitterlipids. Chem Commun (Camb). 2014 Aug 21; 50(65):9109-11. View on Pubmed
  9. Sockolosky JT, Kivimäe S, Szoka FC. Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice. PLoS One. 2014; 9(7):e102566. View on Pubmed
  10. Venditto VJ, Wieczorek L, Molnar S, Teque F, Landucci G, Watson DS, Forthal D, Polonis VR, Levy JA, Szoka FC. Chemically modified peptides based on the membrane-proximal external region of the HIV-1 envelope induce high-titer, epitope-specific nonneutralizing antibodies in rabbits. Clin Vaccine Immunol. 2014 Aug; 21(8):1086-93. View on Pubmed
  11. Kohli AG, Kivimäe S, Tiffany MR, Szoka FC. Improving the distribution of Doxil® in the tumor matrix by depletion of tumor hyaluronan. J Control Release. 2014 Oct 10; 191:105-14. View on Pubmed
  12. Kohli AG, Kierstead PH, Venditto VJ, Walsh CL, Szoka FC. Designer lipids for drug delivery: from heads to tails. J Control Release. 2014 Sep 28; 190:274-87. View on Pubmed
  13. Ruhela D, Kivimäe S, Szoka FC. Chemoenzymatic synthesis of oligohyaluronan-lipid conjugates. Bioconjug Chem. 2014 Apr 16; 25(4):718-23. View on Pubmed
  14. Guo X, Gagne L, Chen H, Szoka FC. Novel ortho ester-based, pH-sensitive cationic lipid for gene delivery in vitro and in vivo. J Liposome Res. 2014 Jun; 24(2):90-8. View on Pubmed
  15. Li M, Yasumura D, Ma AA, Matthes MT, Yang H, Nielson G, Huang Y, Szoka FC, Lavail MM, Diamond MI. Intravitreal administration of HA-1077, a ROCK inhibitor, improves retinal function in a mouse model of huntington disease. PLoS One. 2013; 8(2):e56026. View on Pubmed
  16. Kieler-Ferguson HM, Fréchet JM, Szoka FC. Clinical developments of chemotherapeutic nanomedicines: polymers and liposomes for delivery of camptothecins and platinum (II) drugs. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013 Mar-Apr; 5(2):130-8. View on Pubmed
  17. Walsh CL, Nguyen J, Tiffany MR, Szoka FC. Synthesis, characterization, and evaluation of ionizable lysine-based lipids for siRNA delivery. Bioconjug Chem. 2013 Jan 16; 24(1):36-43. View on Pubmed
  18. Sockolosky JT, Szoka FC. Periplasmic production via the pET expression system of soluble, bioactive human growth hormone. Protein Expr Purif. 2013 Feb; 87(2):129-35. View on Pubmed
  19. Venditto VJ, Watson DS, Motion M, Montefiori D, Szoka FC. Rational design of membrane proximal external region lipopeptides containing chemical modifications for HIV-1 vaccination. Clin Vaccine Immunol. 2013 Jan; 20(1):39-45. View on Pubmed
  20. Venditto VJ, Szoka FC. Cancer nanomedicines: so many papers and so few drugs! Adv Drug Deliv Rev. 2013 Jan; 65(1):80-8. View on Pubmed
  21. Sockolosky JT, Tiffany MR, Szoka FC. Engineering neonatal Fc receptor-mediated recycling and transcytosis in recombinant proteins by short terminal peptide extensions. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16095-100. View on Pubmed
  22. Motion JP, Nguyen J, Szoka FC. Phosphatase-triggered fusogenic liposomes for cytoplasmic delivery of cell-impermeable compounds. Angew Chem Int Ed Engl. 2012 Sep 03; 51(36):9047-51. View on Pubmed
  23. Nguyen J, Walsh CL, Motion JP, Perttu EK, Szoka F. Controlled nucleation of lipid nanoparticles. Pharm Res. 2012 Aug; 29(8):2236-48. View on Pubmed
  24. Walsh CL, Nguyen J, Szoka FC. Synthesis and characterization of novel zwitterionic lipids with pH-responsive biophysical properties. Chem Commun (Camb). 2012 Jun 07; 48(45):5575-7. View on Pubmed
  25. Nguyen J, Szoka FC. Nucleic acid delivery: the missing pieces of the puzzle? Acc Chem Res. 2012 Jul 17; 45(7):1153-62. View on Pubmed
  26. Perttu EK, Kohli AG, Szoka FC. Inverse-phosphocholine lipids: a remix of a common phospholipid. J Am Chem Soc. 2012 Mar 14; 134(10):4485-8. View on Pubmed
  27. Kohli AG, Walsh CL, Szoka FC. Synthesis and characterization of betaine-like diacyl lipids: zwitterionic lipids with the cationic amine at the bilayer interface. Chem Phys Lipids. 2012 Feb; 165(2):252-9. View on Pubmed
  28. Perttu EK, Szoka FC. Zwitterionic sulfobetaine lipids that form vesicles with salt-dependent thermotropic properties. Chem Commun (Camb). 2011 Dec 21; 47(47):12613-5. View on Pubmed
  29. Huang Z, Li W, Szoka FC. Asymmetric 1-alkyl-2-acyl phosphatidylcholine: a helper lipid for enhanced non-viral gene delivery. Int J Pharm. 2012 May 01; 427(1):64-70. View on Pubmed
  30. Foglia F, Barlow DJ, Szoka FC, Huang Z, Rogers SE, Lawrence MJ. Structural studies of the monolayers and bilayers formed by a novel cholesterol-phospholipid chimera. Langmuir. 2011 Jul 05; 27(13):8275-81. View on Pubmed
  31. Riviere K, Kieler-Ferguson HM, Jerger K, Szoka FC. Anti-tumor activity of liposome encapsulated fluoroorotic acid as a single agent and in combination with liposome irinotecan. J Control Release. 2011 Aug 10; 153(3):288-96. View on Pubmed
  32. Chen B, van der Poll DG, Jerger K, Floyd WC, Fréchet JM, Szoka FC. Synthesis and properties of star-comb polymers and their doxorubicin conjugates. Bioconjug Chem. 2011 Apr 20; 22(4):617-24. View on Pubmed
  33. Guy RH, Szoka FC. Perturbation of solute transport at a liquid-liquid interface by polyethylene glycol (PEG): implications for PEG-induced biomembrane fusion. Phys Chem Chem Phys. 2011 Mar 28; 13(12):5346-52. View on Pubmed
  34. Iman M, Huang Z, Szoka FC, Jaafari MR. Characterization of the colloidal properties, in vitro antifungal activity, antileishmanial activity and toxicity in mice of a di-stigma-steryl-hemi-succinoyl-glycero-phosphocholine liposome-intercalated amphotericin B. Int J Pharm. 2011 Apr 15; 408(1-2):163-72. View on Pubmed
  35. Floyd WC, Datta GK, Imamura S, Kieler-Ferguson HM, Jerger K, Patterson AW, Fox ME, Szoka FC, Fréchet JM, Ellman JA. Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice. ChemMedChem. 2011 Jan 03; 6(1):49-53. View on Pubmed
  36. Watson DS, Platt VM, Cao L, Venditto VJ, Szoka FC. Antibody response to polyhistidine-tagged peptide and protein antigens attached to liposomes via lipid-linked nitrilotriacetic acid in mice. Clin Vaccine Immunol. 2011 Feb; 18(2):289-97. View on Pubmed
  37. Motion JP, Huynh GH, Szoka FC, Siegel RA. Convection and retro-convection enhanced delivery: some theoretical considerations related to drug targeting. Pharm Res. 2011 Mar; 28(3):472-9. View on Pubmed
  38. Platt V, Huang Z, Cao L, Tiffany M, Riviere K, Szoka FC. Influence of multivalent nitrilotriacetic acid lipid-ligand affinity on the circulation half-life in mice of a liposome-attached His6-protein. Bioconjug Chem. 2010 May 19; 21(5):892-902. View on Pubmed
  39. van der Poll DG, Kieler-Ferguson HM, Floyd WC, Guillaudeu SJ, Jerger K, Szoka FC, Fréchet JM. Design, synthesis, and biological evaluation of a robust, biodegradable dendrimer. Bioconjug Chem. 2010 Apr 21; 21(4):764-73. View on Pubmed
  40. Riviere K, Huang Z, Jerger K, Macaraeg N, Szoka FC. Antitumor effect of folate-targeted liposomal doxorubicin in KB tumor-bearing mice after intravenous administration. J Drug Target. 2011 Jan; 19(1):14-24. View on Pubmed
  41. Johansen EB, Szoka FC, Zaleski A, Apicella MA, Gibson BW. Utilizing the O-antigen lipopolysaccharide biosynthesis pathway in Escherichia coli to interrogate the substrate specificities of exogenous glycosyltransferase genes in a combinatorial approach. Glycobiology. 2010 Jun; 20(6):763-74. View on Pubmed
  42. Fox ME, Guillaudeu S, Fréchet JM, Jerger K, Macaraeg N, Szoka FC. Synthesis and in vivo antitumor efficacy of PEGylated poly(l-lysine) dendrimer-camptothecin conjugates. Mol Pharm. 2009 Sep-Oct; 6(5):1562-72. View on Pubmed
  43. Fox ME, Szoka FC, Fréchet JM. Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture. Acc Chem Res. 2009 Aug 18; 42(8):1141-51. View on Pubmed
  44. Huang Z, Hwang P, Watson DS, Cao L, Szoka FC. Tris-nitrilotriacetic acids of subnanomolar affinity toward hexahistidine tagged molecules. Bioconjug Chem. 2009 Aug 19; 20(8):1667-72. View on Pubmed
  45. Watson DS, Huang Z, Szoka FC. All-trans retinoic acid potentiates the antibody response in mice to a lipopeptide antigen adjuvanted with liposomal lipid A. Immunol Cell Biol. 2009 Nov-Dec; 87(8):630-3. View on Pubmed
  46. Watson DS, Szoka FC. Role of lipid structure in the humoral immune response in mice to covalent lipid-peptides from the membrane proximal region of HIV-1 gp41. Vaccine. 2009 Jul 23; 27(34):4672-83. View on Pubmed
  47. Chen B, Jerger K, Fréchet JM, Szoka FC. The influence of polymer topology on pharmacokinetics: differences between cyclic and linear PEGylated poly(acrylic acid) comb polymers. J Control Release. 2009 Dec 16; 140(3):203-9. View on Pubmed
  48. Park JI, Cao L, Platt VM, Huang Z, Stull RA, Dy EE, Sperinde JJ, Yokoyama JS, Szoka FC. Antitumor therapy mediated by 5-fluorocytosine and a recombinant fusion protein containing TSG-6 hyaluronan binding domain and yeast cytosine deaminase. Mol Pharm. 2009 May-Jun; 6(3):801-12. View on Pubmed
  49. Nasongkla N, Chen B, Macaraeg N, Fox ME, Fréchet JM, Szoka FC. Dependence of pharmacokinetics and biodistribution on polymer architecture: effect of cyclic versus linear polymers. J Am Chem Soc. 2009 Mar 25; 131(11):3842-3. View on Pubmed
  50. Cohen RN, van der Aa MA, Macaraeg N, Lee AP, Szoka FC. Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection. J Control Release. 2009 Apr 17; 135(2):166-74. View on Pubmed
  51. Huang Z, Jaafari MR, Szoka FC. Disterolphospholipids: nonexchangeable lipids and their application to liposomal drug delivery. Angew Chem Int Ed Engl. 2009; 48(23):4146-9. View on Pubmed
  52. Huang Z, Szoka FC. Sterol-modified phospholipids: cholesterol and phospholipid chimeras with improved biomembrane properties. J Am Chem Soc. 2008 Nov 19; 130(46):15702-12. View on Pubmed
  53. Platt VM, Szoka FC. Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor. Mol Pharm. 2008 Jul-Aug; 5(4):474-86. View on Pubmed
  54. MacKay JA, Li W, Huang Z, Dy EE, Huynh G, Tihan T, Collins R, Deen DF, Szoka FC. HIV TAT peptide modifies the distribution of DNA nanolipoparticles following convection-enhanced delivery. Mol Ther. 2008 May; 16(5):893-900. View on Pubmed
  55. Szoka F. Molecular biology. The art of assembly. Science. 2008 Feb 01; 319(5863):578-9. View on Pubmed
  56. Guillaudeu SJ, Fox ME, Haidar YM, Dy EE, Szoka FC, Fréchet JM. PEGylated dendrimers with core functionality for biological applications. Bioconjug Chem. 2008 Feb; 19(2):461-9. View on Pubmed
  57. Chen H, Zhang H, McCallum CM, Szoka FC, Guo X. Unsaturated cationic ortho esters for endosome permeation in gene delivery. J Med Chem. 2007 Sep 06; 50(18):4269-78. View on Pubmed
  58. Li W, Suez I, Szoka FC. Reconstitution of the M13 major coat protein and its transmembrane peptide segment on a DNA template. Biochemistry. 2007 Jul 24; 46(29):8579-91. View on Pubmed
  59. Karpuj MV, Giles K, Gelibter-Niv S, Scott MR, Lingappa VR, Szoka FC, Peretz D, Denetclaw W, Prusiner SB. Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells. Mol Med. 2007 Mar-Apr; 13(3-4):190-8. View on Pubmed
  60. Li W, Szoka FC. Lipid-based nanoparticles for nucleic acid delivery. Pharm Res. 2007 Mar; 24(3):438-49. View on Pubmed
  61. Huynh GH, Ozawa T, Deen DF, Tihan T, Szoka FC. Retro-convection enhanced delivery to increase blood to brain transfer of macromolecules. Brain Res. 2007 Jan 12; 1128(1):181-90. View on Pubmed
  62. Huang Z, Park JI, Watson DS, Hwang P, Szoka FC. Facile synthesis of multivalent nitrilotriacetic acid (NTA) and NTA conjugates for analytical and drug delivery applications. Bioconjug Chem. 2006 Nov-Dec; 17(6):1592-600. View on Pubmed
  63. Lee CC, Gillies ER, Fox ME, Guillaudeu SJ, Fréchet JM, Dy EE, Szoka FC. A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16649-54. View on Pubmed
  64. Lee CC, Cramer AT, Szoka FC, Fréchet JM. An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin. Bioconjug Chem. 2006 Sep-Oct; 17(5):1364-8. View on Pubmed
  65. Ruhela D, Riviere K, Szoka FC. Efficient synthesis of an aldehyde functionalized hyaluronic acid and its application in the preparation of hyaluronan-lipid conjugates. Bioconjug Chem. 2006 Sep-Oct; 17(5):1360-3. View on Pubmed
  66. Li W, Szoka FC. Bioresponsive targeted charge neutral lipid vesicles for systemic gene delivery. CSH Protoc. 2006 Jun 01; 2006(1). View on Pubmed
  67. Huang Z, Guo X, Li W, MacKay JA, Szoka FC. Acid-triggered transformation of diortho ester phosphocholine liposome. J Am Chem Soc. 2006 Jan 11; 128(1):60-1. View on Pubmed
  68. Lee CC, MacKay JA, Fréchet JM, Szoka FC. Designing dendrimers for biological applications. Nat Biotechnol. 2005 Dec; 23(12):1517-26. View on Pubmed
  69. Huynh GH, Deen DF, Szoka FC. Barriers to carrier mediated drug and gene delivery to brain tumors. J Control Release. 2006 Jan 10; 110(2):236-59. View on Pubmed
  70. Lee CC, Yoshida M, Fréchet JM, Dy EE, Szoka FC. In vitro and in vivo evaluation of hydrophilic dendronized linear polymers. Bioconjug Chem. 2005 May-Jun; 16(3):535-41. View on Pubmed
  71. Gillies ER, Dy E, Fréchet JM, Szoka FC. Biological evaluation of polyester dendrimer: poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture. Mol Pharm. 2005 Mar-Apr; 2(2):129-38. View on Pubmed
  72. Tang MX, Li W, Szoka FC. Toroid formation in charge neutralized flexible or semi-flexible biopolymers: potential pathway for assembly of DNA carriers. J Gene Med. 2005 Mar; 7(3):334-42. View on Pubmed
  73. Huang Z, Li W, MacKay JA, Szoka FC. Thiocholesterol-based lipids for ordered assembly of bioresponsive gene carriers. Mol Ther. 2005 Mar; 11(3):409-17. View on Pubmed
  74. Choi SJ, Sperinde JJ, Szoka FC. Identification of a deoxyribonuclease I inhibitor from a phage-peptide library. Mol Cells. 2005 Feb 28; 19(1):54-9. View on Pubmed
  75. MacKay JA, Deen DF, Szoka FC. Distribution in brain of liposomes after convection enhanced delivery; modulation by particle charge, particle diameter, and presence of steric coating. Brain Res. 2005 Feb 28; 1035(2):139-53. View on Pubmed
  76. Li W, Huang Z, MacKay JA, Grube S, Szoka FC. Low-pH-sensitive poly(ethylene glycol) (PEG)-stabilized plasmid nanolipoparticles: effects of PEG chain length, lipid composition and assembly conditions on gene delivery. J Gene Med. 2005 Jan; 7(1):67-79. View on Pubmed
  77. Cohen RN, Rashkin MJ, Wen X, Szoka FC. Molecular motors as drug delivery vehicles. Drug Discov Today Technol. 2005; 2(1):111-8. View on Pubmed
  78. Li W, Nicol F, Szoka FC. GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery. Adv Drug Deliv Rev. 2004 Apr 23; 56(7):967-85. View on Pubmed
  79. Eliaz RE, Nir S, Marty C, Szoka FC. Determination and modeling of kinetics of cancer cell killing by doxorubicin and doxorubicin encapsulated in targeted liposomes. Cancer Res. 2004 Jan 15; 64(2):711-8. View on Pubmed
  80. Guo X, Huang Z, Szoka FC. Improved preparation of PEG-diortho ester-diacyl glycerol conjugates. Methods Enzymol. 2004; 387:147-52. View on Pubmed
  81. Eliaz RE, Nir S, Szoka FC. Interactions of hyaluronan-targeted liposomes with cultured cells: modeling of binding and endocytosis. Methods Enzymol. 2004; 387:16-33. View on Pubmed
  82. Sonawane ND, Szoka FC, Verkman AS. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem. 2003 Nov 07; 278(45):44826-31. View on Pubmed
  83. Guo X, Szoka FC. Chemical approaches to triggerable lipid vesicles for drug and gene delivery. Acc Chem Res. 2003 May; 36(5):335-41. View on Pubmed
  84. Choi JS, MacKay JA, Szoka FC. Low-pH-sensitive PEG-stabilized plasmid-lipid nanoparticles: preparation and characterization. Bioconjug Chem. 2003 Mar-Apr; 14(2):420-9. View on Pubmed
  85. Guo X, MacKay JA, Szoka FC. Mechanism of pH-triggered collapse of phosphatidylethanolamine liposomes stabilized by an ortho ester polyethyleneglycol lipid. Biophys J. 2003 Mar; 84(3):1784-95. View on Pubmed
  86. Swanson B, Savel R, Szoka F, Sawa T, Wiener-Kronish J. Development of a high throughput Pseudomonas aeruginosa epithelial cell adhesion assay. J Microbiol Methods. 2003 Mar; 52(3):361-6. View on Pubmed
  87. Mackay JA, Szoka FC. HIV TAT Protein Transduction Domain Mediated Cell Binding and Intracellular Delivery of Nanoparticles. J Dispers Sci Technol. 2003; 24(3):465-473. View on Pubmed
  88. Bronich TK, Ouyang M, Kabanov VA, Eisenberg A, Szoka FC, Kabanov AV. Synthesis of vesicles on polymer template. J Am Chem Soc. 2002 Oct 09; 124(40):11872-3. View on Pubmed
  89. Eliaz RE, Szoka FC. Robust and prolonged gene expression from injectable polymeric implants. Gene Ther. 2002 Sep; 9(18):1230-7. View on Pubmed
  90. Padilla De Jesús OL, Ihre HR, Gagne L, Fréchet JM, Szoka FC. Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation. Bioconjug Chem. 2002 May-Jun; 13(3):453-61. View on Pubmed
  91. Ihre HR, Padilla De Jesús OL, Szoka FC, Fréchet JM. Polyester dendritic systems for drug delivery applications: design, synthesis, and characterization. Bioconjug Chem. 2002 May-Jun; 13(3):443-52. View on Pubmed
  92. Uyechi LS, Gagné L, Thurston G, Szoka FC. Mechanism of lipoplex gene delivery in mouse lung: binding and internalization of fluorescent lipid and DNA components. Gene Ther. 2001 Jun; 8(11):828-36. View on Pubmed
  93. Supattapone S, Wille H, Uyechi L, Safar J, Tremblay P, Szoka FC, Cohen FE, Prusiner SB, Scott MR. Branched polyamines cure prion-infected neuroblastoma cells. J Virol. 2001 Apr; 75(7):3453-61. View on Pubmed
  94. Eliaz RE, Szoka FC. Liposome-encapsulated doxorubicin targeted to CD44: a strategy to kill CD44-overexpressing tumor cells. Cancer Res. 2001 Mar 15; 61(6):2592-601. View on Pubmed
  95. Guo X, Szoka FC. Steric stabilization of fusogenic liposomes by a low-pH sensitive PEG--diortho ester--lipid conjugate. Bioconjug Chem. 2001 Mar-Apr; 12(2):291-300. View on Pubmed
  96. Sperinde JJ, Choi SJ, Szoka FC. Phage display selection of a peptide DNase II inhibitor that enhances gene delivery. J Gene Med. 2001 Mar-Apr; 3(2):101-8. View on Pubmed
  97. Sparrer HE, Santoso A, Szoka FC, Weissman JS. Evidence for the prion hypothesis: induction of the yeast [PSI+] factor by in vitro- converted Sup35 protein. Science. 2000 Jul 28; 289(5479):595-9. View on Pubmed
  98. Choi SJ, Szoka FC. Fluorometric determination of deoxyribonuclease I activity with PicoGreen. Anal Biochem. 2000 May 15; 281(1):95-7. View on Pubmed
  99. Nicol F, Nir S, Szoka FC. Effect of phospholipid composition on an amphipathic peptide-mediated pore formation in bilayer vesicles. Biophys J. 2000 Feb; 78(2):818-29. View on Pubmed
  100. Ouyang M, Remy JS, Szoka FC. Controlled template-assisted assembly of plasmid DNA into nanometric particles with high DNA concentration. Bioconjug Chem. 2000 Jan-Feb; 11(1):104-12. View on Pubmed
  101. Urtti A, Polansky J, Lui GM, Szoka FC. Gene delivery and expression in human retinal pigment epithelial cells: effects of synthetic carriers, serum, extracellular matrix and viral promoters. J Drug Target. 2000; 7(6):413-21. View on Pubmed
  102. Hirota S, de Ilarduya CT, Barron LG, Szoka FC. Simple mixing device to reproducibly prepare cationic lipid-DNA complexes (lipoplexes). Biotechniques. 1999 Aug; 27(2):286-90. View on Pubmed
  103. Barron LG, Gagné L, Szoka FC. Lipoplex-mediated gene delivery to the lung occurs within 60 minutes of intravenous administration. Hum Gene Ther. 1999 Jul 01; 10(10):1683-94. View on Pubmed
  104. Xu Y, Hui SW, Frederik P, Szoka FC. Physicochemical characterization and purification of cationic lipoplexes. Biophys J. 1999 Jul; 77(1):341-53. View on Pubmed
  105. Barron LG, Uyechi LS, Szoka FC. Cationic lipids are essential for gene delivery mediated by intravenous administration of lipoplexes. Gene Ther. 1999 Jun; 6(6):1179-83. View on Pubmed
  106. Nicol F, Nir S, Szoka FC. Orientation of the pore-forming peptide GALA in POPC vesicles determined by a BODIPY-avidin/biotin binding assay. Biophys J. 1999 Apr; 76(4):2121-41. View on Pubmed
  107. Plank C, Tang MX, Wolfe AR, Szoka FC. Branched cationic peptides for gene delivery: role of type and number of cationic residues in formation and in vitro activity of DNA polyplexes. Hum Gene Ther. 1999 Jan 20; 10(2):319-32. View on Pubmed
  108. Nir S, Nicol F, Szoka FC. Surface aggregation and membrane penetration by peptides: relation to pore formation and fusion. Mol Membr Biol. 1999 Jan-Mar; 16(1):95-101. View on Pubmed
  109. Turunen MP, Hiltunen MO, Ruponen M, Virkamäki L, Szoka FC, Urtti A, Ylä-Herttuala S. Efficient adventitial gene delivery to rabbit carotid artery with cationic polymer-plasmid complexes. Gene Ther. 1999 Jan; 6(1):6-11. View on Pubmed
  110. Peschka R, Dennehy C, Szoka FC. A simple in vitro model to study the release kinetics of liposome encapsulated material. J Control Release. 1998 Dec 04; 56(1-3):41-51. View on Pubmed
  111. Davis SC, Szoka FC. Cholesterol phosphate derivatives: synthesis and incorporation into a phosphatase and calcium-sensitive triggered release liposome. Bioconjug Chem. 1998 Nov-Dec; 9(6):783-92. View on Pubmed
  112. Wang J, Guo X, Xu Y, Barron L, Szoka FC. Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery. J Med Chem. 1998 Jun 18; 41(13):2207-15. View on Pubmed
  113. Zelphati O, Uyechi LS, Barron LG, Szoka FC. Effect of serum components on the physico-chemical properties of cationic lipid/oligonucleotide complexes and on their interactions with cells. Biochim Biophys Acta. 1998 Feb 16; 1390(2):119-33. View on Pubmed
  114. Barron LG, Meyer KB, Szoka FC. Effects of complement depletion on the pharmacokinetics and gene delivery mediated by cationic lipid-DNA complexes. Hum Gene Ther. 1998 Feb 10; 9(3):315-23. View on Pubmed
  115. Swaan PW, Szoka FC, Oie S. Molecular modeling of the intestinal bile acid carrier: a comparative molecular field analysis study. J Comput Aided Mol Des. 1997 Nov; 11(6):581-8. View on Pubmed
  116. Tang MX, Szoka FC. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther. 1997 Aug; 4(8):823-32. View on Pubmed
  117. Swaan PW, Hillgren KM, Szoka FC, Oie S. Enhanced transepithelial transport of peptides by conjugation to cholic acid. Bioconjug Chem. 1997 Jul-Aug; 8(4):520-5. View on Pubmed
  118. Szoka FC. Many are probed, but few are chosen. Nat Biotechnol. 1997 Jun; 15(6):509. View on Pubmed
  119. Felgner PL, Barenholz Y, Behr JP, Cheng SH, Cullis P, Huang L, Jessee JA, Seymour L, Szoka F, Thierry AR, Wagner E, Wu G. Nomenclature for synthetic gene delivery systems. Hum Gene Ther. 1997 Mar 20; 8(5):511-2. View on Pubmed
  120. Wyman TB, Nicol F, Zelphati O, Scaria PV, Plank C, Szoka FC. Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry. 1997 Mar 11; 36(10):3008-17. View on Pubmed
  121. Kågedahl M, Swaan PW, Redemann CT, Tang M, Craik CS, Szoka FC, Oie S. Use of the intestinal bile acid transporter for the uptake of cholic acid conjugates with HIV-1 protease inhibitory activity. Pharm Res. 1997 Feb; 14(2):176-80. View on Pubmed
  122. Nicol F, Nir S, Szoka FC. Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide. Biophys J. 1996 Dec; 71(6):3288-301. View on Pubmed
  123. Tang MX, Redemann CT, Szoka FC. In vitro gene delivery by degraded polyamidoamine dendrimers. Bioconjug Chem. 1996 Nov-Dec; 7(6):703-14. View on Pubmed
  124. Zelphati O, Szoka FC. Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11493-8. View on Pubmed
  125. Zelphati O, Szoka FC. Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids. Pharm Res. 1996 Sep; 13(9):1367-72. View on Pubmed
  126. Plank C, Mechtler K, Szoka FC, Wagner E. Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. Hum Gene Ther. 1996 Aug 01; 7(12):1437-46. View on Pubmed
  127. Xu Y, Szoka FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry. 1996 May 07; 35(18):5616-23. View on Pubmed
  128. van der Geest R, Hueber F, Szoka FC, Guy RH. Iontophoresis of bases, nucleosides, and nucleotides. Pharm Res. 1996 Apr; 13(4):553-8. View on Pubmed
  129. Levy MY, Barron LG, Meyer KB, Szoka FC. Characterization of plasmid DNA transfer into mouse skeletal muscle: evaluation of uptake mechanism, expression and secretion of gene products into blood. Gene Ther. 1996 Mar; 3(3):201-11. View on Pubmed
  130. Stull RA, Zon G, Szoka FC. An in vitro messenger RNA binding assay as a tool for identifying hybridization-competent antisense oligonucleotides. Antisense Nucleic Acid Drug Dev. 1996; 6(3):221-8. View on Pubmed
  131. Meyer KB, Thompson MM, Levy MY, Barron LG, Szoka FC. Intratracheal gene delivery to the mouse airway: characterization of plasmid DNA expression and pharmacokinetics. Gene Ther. 1995 Sep; 2(7):450-60. View on Pubmed
  132. Stull RA, Szoka FC. Antigene, ribozyme and aptamer nucleic acid drugs: progress and prospects. Pharm Res. 1995 Apr; 12(4):465-83. View on Pubmed
  133. Hickman MA, Malone RW, Lehmann-Bruinsma K, Sih TR, Knoell D, Szoka FC, Walzem R, Carlson DM, Powell JS. Gene expression following direct injection of DNA into liver. Hum Gene Ther. 1994 Dec; 5(12):1477-83. View on Pubmed
  134. Fattal E, Nir S, Parente RA, Szoka FC. Pore-forming peptides induce rapid phospholipid flip-flop in membranes. Biochemistry. 1994 May 31; 33(21):6721-31. View on Pubmed
  135. Sixou S, Szoka FC, Green GA, Giusti B, Zon G, Chin DJ. Intracellular oligonucleotide hybridization detected by fluorescence resonance energy transfer (FRET). Nucleic Acids Res. 1994 Feb 25; 22(4):662-8. View on Pubmed
  136. Haensler J, Szoka FC. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug Chem. 1993 Sep-Oct; 4(5):372-9. View on Pubmed
  137. Legendre JY, Szoka FC. Cyclic amphipathic peptide-DNA complexes mediate high-efficiency transfection of adherent mammalian cells. Proc Natl Acad Sci U S A. 1993 Feb 01; 90(3):893-7. View on Pubmed
  138. Stull RA, Zon G, Szoka FC. Single-stranded phosphodiester and phosphorothioate oligonucleotides bind actinomycin D and interfere with tumor necrosis factor-induced lysis in the L929 cytotoxicity assay. Antisense Res Dev. 1993; 3(3):295-300. View on Pubmed
  139. Haensler J, Szoka FC. Synthesis and characterization of a trigalactosylated bisacridine compound to target DNA to hepatocytes. Bioconjug Chem. 1993 Jan-Feb; 4(1):85-93. View on Pubmed
  140. Legendre JY, Szoka FC. Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: comparison with cationic liposomes. Pharm Res. 1992 Oct; 9(10):1235-42. View on Pubmed
  141. Stull RA, Taylor LA, Szoka FC. Predicting antisense oligonucleotide inhibitory efficacy: a computational approach using histograms and thermodynamic indices. Nucleic Acids Res. 1992 Jul 11; 20(13):3501-8. View on Pubmed
  142. Kim A, Szoka FC. Amino acid side-chain contributions to free energy of transfer of tripeptides from water to octanol. Pharm Res. 1992 Apr; 9(4):504-14. View on Pubmed
  143. Woodle MC, Storm G, Newman MS, Jekot JJ, Collins LR, Martin FJ, Szoka FC. Prolonged systemic delivery of peptide drugs by long-circulating liposomes: illustration with vasopressin in the Brattleboro rat. Pharm Res. 1992 Feb; 9(2):260-5. View on Pubmed
  144. Szoka FC. The macrophage as the principal antigen-presenting cell for liposome-encapsulated antigen. Res Immunol. 1992 Feb; 143(2):186-8. View on Pubmed
  145. Green PG, Hinz RS, Kim A, Szoka FC, Guy RH. Iontophoretic delivery of a series of tripeptides across the skin in vitro. Pharm Res. 1991 Sep; 8(9):1121-7. View on Pubmed
  146. Goormaghtigh E, De Meutter J, Szoka F, Cabiaux V, Parente RA, Ruysschaert JM. Secondary structure and orientation of the amphipathic peptide GALA in lipid structures. An infrared-spectroscopic approach. Eur J Biochem. 1991 Jan 30; 195(2):421-9. View on Pubmed
  147. Chin DJ, Green GA, Zon G, Szoka FC, Straubinger RM. Rapid nuclear accumulation of injected oligodeoxyribonucleotides. New Biol. 1990 Dec; 2(12):1091-100. View on Pubmed
  148. Szoka FC. The future of liposomal drug delivery. Biotechnol Appl Biochem. 1990 Oct; 12(5):496-500. View on Pubmed
  149. Parente RA, Nadasdi L, Subbarao NK, Szoka FC. Association of a pH-sensitive peptide with membrane vesicles: role of amino acid sequence. Biochemistry. 1990 Sep 18; 29(37):8713-9. View on Pubmed
  150. Parente RA, Nir S, Szoka FC. Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA. Biochemistry. 1990 Sep 18; 29(37):8720-8. View on Pubmed
  151. Chu CJ, Dijkstra J, Lai MZ, Hong K, Szoka FC. Efficiency of cytoplasmic delivery by pH-sensitive liposomes to cells in culture. Pharm Res. 1990 Aug; 7(8):824-34. View on Pubmed
  152. Roe JN, Szoka FC, Verkman AS. Fibre optic sensor for the detection of potassium using fluorescence energy transfer. Analyst. 1990 Apr; 115(4):353-8. View on Pubmed
  153. Dal Monte PR, Szoka FC. Antigen presentation by B cells and macrophages of cytochrome c and its antigenic fragment when conjugated to the surface of liposomes. Vaccine. 1989 Oct; 7(5):401-8. View on Pubmed
  154. Roe JN, Szoka FC, Verkman AS. Optical measurement of aqueous potassium concentration by a hydrophobic indicator in lipid vesicles. Biophys Chem. 1989 Jul; 33(3):295-302. View on Pubmed
  155. Patterson TF, Miniter P, Dijkstra J, Szoka FC, Ryan JL, Andriole VT. Treatment of experimental invasive aspergillosis with novel amphotericin B/cholesterol-sulfate complexes. J Infect Dis. 1989 Apr; 159(4):717-24. View on Pubmed
  156. Dal Monte P, Szoka FC. Effect of liposome encapsulation on antigen presentation in vitro. Comparison of presentation by peritoneal macrophages and B cell tumors. J Immunol. 1989 Mar 01; 142(5):1437-43. View on Pubmed
  157. Dijkstra J, Ryan JL, Szoka FC. A procedure for the efficient incorporation of wild-type lipopolysaccharide into liposomes for use in immunological studies. J Immunol Methods. 1988 Nov 10; 114(1-2):197-205. View on Pubmed
  158. Szoka FC, Chu CJ. Increased efficacy of phosphonoformate and phosphonoacetate inhibition of herpes simplex virus type 2 replication by encapsulation in liposomes. Antimicrob Agents Chemother. 1988 Jun; 32(6):858-64. View on Pubmed
  159. Dijkstra J, Larrick JW, Ryan JL, Szoka FC. Incorporation of LPS in liposomes diminishes its ability to induce tumoricidal activity and tumor necrosis factor secretion in murine macrophages. J Leukoc Biol. 1988 May; 43(5):436-44. View on Pubmed
  160. Parente RA, Nir S, Szoka FC. pH-dependent fusion of phosphatidylcholine small vesicles. Induction by a synthetic amphipathic peptide. J Biol Chem. 1988 Apr 05; 263(10):4724-30. View on Pubmed
  161. Subbarao NK, Fielding CJ, Hamilton RL, Szoka FC. Lecithin:cholesterol acyltransferase activation by synthetic amphipathic peptides. Proteins. 1988; 3(3):187-98. View on Pubmed
  162. Subbarao NK, Parente RA, Szoka FC, Nadasdi L, Pongracz K. pH-dependent bilayer destabilization by an amphipathic peptide. Biochemistry. 1987 Jun 02; 26(11):2964-72. View on Pubmed
  163. Barza M, Stuart M, Szoka F. Effect of size and lipid composition on the pharmacokinetics of intravitreal liposomes. Invest Ophthalmol Vis Sci. 1987 May; 28(5):893-900. View on Pubmed
  164. Bentz J, Ellens H, Szoka FC. Destabilization of phosphatidylethanolamine-containing liposomes: hexagonal phase and asymmetric membranes. Biochemistry. 1987 Apr 21; 26(8):2105-16. View on Pubmed
  165. Dijkstra J, Mellors JW, Ryan JL, Szoka FC. Modulation of the biological activity of bacterial endotoxin by incorporation into liposomes. J Immunol. 1987 Apr 15; 138(8):2663-70. View on Pubmed
  166. Szoka FC, Milholland D, Barza M. Effect of lipid composition and liposome size on toxicity and in vitro fungicidal activity of liposome-intercalated amphotericin B. Antimicrob Agents Chemother. 1987 Mar; 31(3):421-9. View on Pubmed
  167. Szoka FC, Jones CS. Uptake of liposome-encapsulated agents. Methods Enzymol. 1987; 149:143-7. View on Pubmed
  168. Ellens H, Bentz J, Szoka FC. Fusion of phosphatidylethanolamine-containing liposomes and mechanism of the L alpha-HII phase transition. Biochemistry. 1986 Jul 15; 25(14):4141-7. View on Pubmed
  169. Ellens H, Bentz J, Szoka FC. Destabilization of phosphatidylethanolamine liposomes at the hexagonal phase transition temperature. Biochemistry. 1986 Jan 28; 25(2):285-94. View on Pubmed
  170. Bentz J, Ellens H, Lai MZ, Szoka FC. On the correlation between HII phase and the contact-induced destabilization of phosphatidylethanolamine-containing membranes. Proc Natl Acad Sci U S A. 1985 Sep; 82(17):5742-5. View on Pubmed
  171. Barza M, Baum J, Tremblay C, Szoka F, D'Amico DJ. Ocular toxicity of intravitreally injected liposomal amphotericin B in rhesus monkeys. Am J Ophthalmol. 1985 Aug 15; 100(2):259-63. View on Pubmed
  172. Ellens H, Bentz J, Szoka FC. H+- and Ca2+-induced fusion and destabilization of liposomes. Biochemistry. 1985 Jun 18; 24(13):3099-106. View on Pubmed
  173. Tremblay C, Barza M, Szoka F, Lahav M, Baum J. Reduced toxicity of liposome-associated amphotericin B injected intravitreally in rabbits. Invest Ophthalmol Vis Sci. 1985 May; 26(5):711-8. View on Pubmed
  174. Lai MZ, Vail WJ, Szoka FC. Acid- and calcium-induced structural changes in phosphatidylethanolamine membranes stabilized by cholesteryl hemisuccinate. Biochemistry. 1985 Mar 26; 24(7):1654-61. View on Pubmed
  175. Lai MZ, Düzgünes N, Szoka FC. Effects of replacement of the hydroxyl group of cholesterol and tocopherol on the thermotropic behavior of phospholipid membranes. Biochemistry. 1985 Mar 26; 24(7):1646-53. View on Pubmed
  176. Tremblay C, Barza M, Fiore C, Szoka F. Efficacy of liposome-intercalated amphotericin B in the treatment of systemic candidiasis in mice. Antimicrob Agents Chemother. 1984 Aug; 26(2):170-3. View on Pubmed
  177. Panosian CB, Barza M, Szoka F, Wyler DJ. Treatment of experimental cutaneous leishmaniasis with liposome-intercalated amphotericin B. Antimicrob Agents Chemother. 1984 May; 25(5):655-6. View on Pubmed
  178. Barza M, Baum J, Szoka F. Pharmacokinetics of subconjunctival liposome-encapsulated gentamicin in normal rabbit eyes. Invest Ophthalmol Vis Sci. 1984 Apr; 25(4):486-90. View on Pubmed
  179. Ellens H, Bentz J, Szoka FC. pH-induced destabilization of phosphatidylethanolamine-containing liposomes: role of bilayer contact. Biochemistry. 1984 Mar 27; 23(7):1532-8. View on Pubmed
  180. Szoka FC, Mayhew E. Alteration of liposome disposition in vivo by bilayer situated carbohydrates. Biochem Biophys Res Commun. 1983 Jan 14; 110(1):140-6. View on Pubmed
  181. Abra RM, Schreier H, Szoka FC. The use of a new radioactive-iodine labeled lipid marker to follow in vivo disposition of liposomes: comparison with an encapsulated aqueous space marker. Res Commun Chem Pathol Pharmacol. 1982 Aug; 37(2):199-213. View on Pubmed
  182. Alroy J, Szoka FC, Heaney JA, Ucci AA. Lectins as a probe for carbohydrate residues in non-neoplastic urothelium of human urinary bladder. J Urol. 1982 Jul; 128(1):189-93. View on Pubmed
  183. Olson F, Mayhew E, Maslow D, Rustum Y, Szoka F. Characterization, toxicity and therapeutic efficacy of adriamycin encapsulated in liposomes. Eur J Cancer Clin Oncol. 1982 Feb; 18(2):167-76. View on Pubmed
  184. Kirkland JJ, Yau WW, Szoka FC. Sedimentation field flow fractionation of liposomes. Science. 1982 Jan 15; 215(4530):296-8. View on Pubmed
  185. Rustum YM, Mayhew E, Szoka F, Campbell J. Inability of liposome encapsulated 1-beta-D-arabinofuranosylcytosine nucleotides to overcome drug resistance in L1210 cells. Eur J Cancer Clin Oncol. 1981 Jul; 17(7):809-17. View on Pubmed
  186. Szoka F, Magnusson KE, Wojcieszyn J, Hou Y, Derzko Z, Jacobson K. Use of lectins and polyethylene glycol for fusion of glycolipid-containing liposomes with eukaryotic cells. Proc Natl Acad Sci U S A. 1981 Mar; 78(3):1685-9. View on Pubmed
  187. Szoka F, Olson F, Heath T, Vail W, Mayhew E, Papahadjopoulos D. Preparation of unilamellar liposomes of intermediate size (0.1-0.2 mumol) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes. Biochim Biophys Acta. 1980 Oct 02; 601(3):559-71. View on Pubmed
  188. Szoka F, Jacobson K, Derzko Z, Papahadjopoulos D. Fluorescence studies on the mechanism of liposome-cell interactions in vitro. Biochim Biophys Acta. 1980 Jul 16; 600(1):1-18. View on Pubmed
  189. Szoka F, Papahadjopoulos D. Comparative properties and methods of preparation of lipid vesicles (liposomes). Annu Rev Biophys Bioeng. 1980; 9:467-508. View on Pubmed
  190. Mayhew E, Rustum YM, Szoka F, Papahadjopoulos D. Role of cholesterol in enhancing the antitumor activity of cytosine arabinoside entrapped in liposomes. Cancer Treat Rep. 1979 Nov-Dec; 63(11-12):1923-8. View on Pubmed
  191. Near JA, Szoka FC, Olsen R, Ettinger MJ. Photoaffinity labeling of three renal cyclic 3',5'-adenosine monophosphate-binding proteins. Biochim Biophys Acta. 1979 Nov 01; 587(4):522-39. View on Pubmed
  192. Olson F, Hunt CA, Szoka FC, Vail WJ, Papahadjopoulos D. Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes. Biochim Biophys Acta. 1979 Oct 19; 557(1):9-23. View on Pubmed
  193. Saffran M, Franco-Saenz R, Kong A, Papahadjopoulos D, Szoka F. A model for the study of the oral administration of peptide hormones. Can J Biochem. 1979 Jun; 57(6):548-53. View on Pubmed
  194. Szoka FC, Jacobson K, Papahadjopoulos D. The use of aqueous space markers to determine the mechanism of interaction between phospholipid vesicles and cells. Biochim Biophys Acta. 1979 Mar 08; 551(2):295-303. View on Pubmed
  195. Wu ES, Jacobson K, Szoka F, Portis A. Lateral diffusion of a hydrophobic peptide, N-4-nitrobenz-2-oxa-1,3-diazole gramicidin S, in phospholipid multibilayers. Biochemistry. 1978 Dec 12; 17(25):5543-50. View on Pubmed
  196. Szoka FC, Ettinger MJ. Adenosine 3' :5' -monophosphate-dependnet phosphorylations of renal subcellular fractions. Differences between cortical and medullary membrane preparations. J Biol Chem. 1978 Sep 25; 253(18):6536-43. View on Pubmed
  197. Szoka F, Papahadjopoulos D. Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation. Proc Natl Acad Sci U S A. 1978 Sep; 75(9):4194-8. View on Pubmed
  198. Iman M, Huang Z, Alavizadeh SH, Szoka FC, Jaafari MR. Biodistribution and In Vivo Antileishmanial Activity of 1,2-Distigmasterylhemisuccinoyl-sn-Glycero-3-Phosphocholine Liposome-Intercalated Amphotericin B. Antimicrob Agents Chemother. 2017 Sep; 61(9). View on Pubmed
  199. Kieler-Ferguson HM, Chan D, Sockolosky J, Finney L, Maxey E, Vogt S, Szoka FC. Encapsulation, controlled release, and antitumor efficacy of cisplatin delivered in liposomes composed of sterol-modified phospholipids. Eur J Pharm Sci. 2017 May 30; 103:85-93. View on Pubmed
  200. Tiffany M, Szoka FC. Co-localization of fluorescent labeled lipid nanoparticles with specifically tagged subcellular compartments by single particle tracking at low nanoparticle to cell ratios. J Drug Target. 2016 Nov; 24(9):857-864. View on Pubmed
  201. Yuan W, Kuai R, Dai Z, Yuan Y, Zheng N, Jiang W, Noble C, Hayes M, Szoka FC, Schwendeman A. Development of a Flow-Through USP-4 Apparatus Drug Release Assay to Evaluate Doxorubicin Liposomes. AAPS J. 2017 Jan; 19(1):150-160. View on Pubmed
  202. Lee S, Kivimäe S, Dolor A, Szoka FC. Macrophage-based cell therapies: The long and winding road. J Control Release. 2016 Oct 28; 240:527-540. View on Pubmed
  203. Kierstead PH, Okochi H, Venditto VJ, Chuong TC, Kivimae S, Fréchet JMJ, Szoka FC. The effect of polymer backbone chemistry on the induction of the accelerated blood clearance in polymer modified liposomes. J Control Release. 2015 Sep 10; 213:1-9. View on Pubmed
  204. Sockolosky JT, Szoka FC. The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy. Adv Drug Deliv Rev. 2015 Aug 30; 91:109-24. View on Pubmed
  205. Venditto VJ, Dolor A, Kohli A, Salentinig S, Boyd BJ, Szoka FC. Sulfated quaternary amine lipids: a new class of inverse charge zwitterlipids. Chem Commun (Camb). 2014 Aug 21; 50(65):9109-11. View on Pubmed
  206. Sockolosky JT, Kivimäe S, Szoka FC. Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice. PLoS One. 2014; 9(7):e102566. View on Pubmed
  207. Venditto VJ, Wieczorek L, Molnar S, Teque F, Landucci G, Watson DS, Forthal D, Polonis VR, Levy JA, Szoka FC. Chemically modified peptides based on the membrane-proximal external region of the HIV-1 envelope induce high-titer, epitope-specific nonneutralizing antibodies in rabbits. Clin Vaccine Immunol. 2014 Aug; 21(8):1086-93. View on Pubmed
  208. Kohli AG, Kivimäe S, Tiffany MR, Szoka FC. Improving the distribution of Doxil® in the tumor matrix by depletion of tumor hyaluronan. J Control Release. 2014 Oct 10; 191:105-14. View on Pubmed
  209. Kohli AG, Kierstead PH, Venditto VJ, Walsh CL, Szoka FC. Designer lipids for drug delivery: from heads to tails. J Control Release. 2014 Sep 28; 190:274-87. View on Pubmed
  210. Ruhela D, Kivimäe S, Szoka FC. Chemoenzymatic synthesis of oligohyaluronan-lipid conjugates. Bioconjug Chem. 2014 Apr 16; 25(4):718-23. View on Pubmed
  211. Guo X, Gagne L, Chen H, Szoka FC. Novel ortho ester-based, pH-sensitive cationic lipid for gene delivery in vitro and in vivo. J Liposome Res. 2014 Jun; 24(2):90-8. View on Pubmed
  212. Li M, Yasumura D, Ma AA, Matthes MT, Yang H, Nielson G, Huang Y, Szoka FC, Lavail MM, Diamond MI. Intravitreal administration of HA-1077, a ROCK inhibitor, improves retinal function in a mouse model of huntington disease. PLoS One. 2013; 8(2):e56026. View on Pubmed
  213. Kieler-Ferguson HM, Fréchet JM, Szoka FC. Clinical developments of chemotherapeutic nanomedicines: polymers and liposomes for delivery of camptothecins and platinum (II) drugs. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013 Mar-Apr; 5(2):130-8. View on Pubmed
  214. Walsh CL, Nguyen J, Tiffany MR, Szoka FC. Synthesis, characterization, and evaluation of ionizable lysine-based lipids for siRNA delivery. Bioconjug Chem. 2013 Jan 16; 24(1):36-43. View on Pubmed
  215. Sockolosky JT, Szoka FC. Periplasmic production via the pET expression system of soluble, bioactive human growth hormone. Protein Expr Purif. 2013 Feb; 87(2):129-35. View on Pubmed
  216. Venditto VJ, Watson DS, Motion M, Montefiori D, Szoka FC. Rational design of membrane proximal external region lipopeptides containing chemical modifications for HIV-1 vaccination. Clin Vaccine Immunol. 2013 Jan; 20(1):39-45. View on Pubmed
  217. Venditto VJ, Szoka FC. Cancer nanomedicines: so many papers and so few drugs! Adv Drug Deliv Rev. 2013 Jan; 65(1):80-8. View on Pubmed
  218. Sockolosky JT, Tiffany MR, Szoka FC. Engineering neonatal Fc receptor-mediated recycling and transcytosis in recombinant proteins by short terminal peptide extensions. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16095-100. View on Pubmed
  219. Motion JP, Nguyen J, Szoka FC. Phosphatase-triggered fusogenic liposomes for cytoplasmic delivery of cell-impermeable compounds. Angew Chem Int Ed Engl. 2012 Sep 03; 51(36):9047-51. View on Pubmed
  220. Nguyen J, Walsh CL, Motion JP, Perttu EK, Szoka F. Controlled nucleation of lipid nanoparticles. Pharm Res. 2012 Aug; 29(8):2236-48. View on Pubmed
  221. Walsh CL, Nguyen J, Szoka FC. Synthesis and characterization of novel zwitterionic lipids with pH-responsive biophysical properties. Chem Commun (Camb). 2012 Jun 07; 48(45):5575-7. View on Pubmed
  222. Nguyen J, Szoka FC. Nucleic acid delivery: the missing pieces of the puzzle? Acc Chem Res. 2012 Jul 17; 45(7):1153-62. View on Pubmed
  223. Perttu EK, Kohli AG, Szoka FC. Inverse-phosphocholine lipids: a remix of a common phospholipid. J Am Chem Soc. 2012 Mar 14; 134(10):4485-8. View on Pubmed
  224. Kohli AG, Walsh CL, Szoka FC. Synthesis and characterization of betaine-like diacyl lipids: zwitterionic lipids with the cationic amine at the bilayer interface. Chem Phys Lipids. 2012 Feb; 165(2):252-9. View on Pubmed
  225. Perttu EK, Szoka FC. Zwitterionic sulfobetaine lipids that form vesicles with salt-dependent thermotropic properties. Chem Commun (Camb). 2011 Dec 21; 47(47):12613-5. View on Pubmed
  226. Huang Z, Li W, Szoka FC. Asymmetric 1-alkyl-2-acyl phosphatidylcholine: a helper lipid for enhanced non-viral gene delivery. Int J Pharm. 2012 May 01; 427(1):64-70. View on Pubmed
  227. Foglia F, Barlow DJ, Szoka FC, Huang Z, Rogers SE, Lawrence MJ. Structural studies of the monolayers and bilayers formed by a novel cholesterol-phospholipid chimera. Langmuir. 2011 Jul 05; 27(13):8275-81. View on Pubmed
  228. Riviere K, Kieler-Ferguson HM, Jerger K, Szoka FC. Anti-tumor activity of liposome encapsulated fluoroorotic acid as a single agent and in combination with liposome irinotecan. J Control Release. 2011 Aug 10; 153(3):288-96. View on Pubmed
  229. Chen B, van der Poll DG, Jerger K, Floyd WC, Fréchet JM, Szoka FC. Synthesis and properties of star-comb polymers and their doxorubicin conjugates. Bioconjug Chem. 2011 Apr 20; 22(4):617-24. View on Pubmed
  230. Guy RH, Szoka FC. Perturbation of solute transport at a liquid-liquid interface by polyethylene glycol (PEG): implications for PEG-induced biomembrane fusion. Phys Chem Chem Phys. 2011 Mar 28; 13(12):5346-52. View on Pubmed
  231. Iman M, Huang Z, Szoka FC, Jaafari MR. Characterization of the colloidal properties, in vitro antifungal activity, antileishmanial activity and toxicity in mice of a di-stigma-steryl-hemi-succinoyl-glycero-phosphocholine liposome-intercalated amphotericin B. Int J Pharm. 2011 Apr 15; 408(1-2):163-72. View on Pubmed
  232. Floyd WC, Datta GK, Imamura S, Kieler-Ferguson HM, Jerger K, Patterson AW, Fox ME, Szoka FC, Fréchet JM, Ellman JA. Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice. ChemMedChem. 2011 Jan 03; 6(1):49-53. View on Pubmed
  233. Watson DS, Platt VM, Cao L, Venditto VJ, Szoka FC. Antibody response to polyhistidine-tagged peptide and protein antigens attached to liposomes via lipid-linked nitrilotriacetic acid in mice. Clin Vaccine Immunol. 2011 Feb; 18(2):289-97. View on Pubmed
  234. Motion JP, Huynh GH, Szoka FC, Siegel RA. Convection and retro-convection enhanced delivery: some theoretical considerations related to drug targeting. Pharm Res. 2011 Mar; 28(3):472-9. View on Pubmed
  235. Platt V, Huang Z, Cao L, Tiffany M, Riviere K, Szoka FC. Influence of multivalent nitrilotriacetic acid lipid-ligand affinity on the circulation half-life in mice of a liposome-attached His6-protein. Bioconjug Chem. 2010 May 19; 21(5):892-902. View on Pubmed
  236. van der Poll DG, Kieler-Ferguson HM, Floyd WC, Guillaudeu SJ, Jerger K, Szoka FC, Fréchet JM. Design, synthesis, and biological evaluation of a robust, biodegradable dendrimer. Bioconjug Chem. 2010 Apr 21; 21(4):764-73. View on Pubmed
  237. Riviere K, Huang Z, Jerger K, Macaraeg N, Szoka FC. Antitumor effect of folate-targeted liposomal doxorubicin in KB tumor-bearing mice after intravenous administration. J Drug Target. 2011 Jan; 19(1):14-24. View on Pubmed
  238. Johansen EB, Szoka FC, Zaleski A, Apicella MA, Gibson BW. Utilizing the O-antigen lipopolysaccharide biosynthesis pathway in Escherichia coli to interrogate the substrate specificities of exogenous glycosyltransferase genes in a combinatorial approach. Glycobiology. 2010 Jun; 20(6):763-74. View on Pubmed
  239. Fox ME, Guillaudeu S, Fréchet JM, Jerger K, Macaraeg N, Szoka FC. Synthesis and in vivo antitumor efficacy of PEGylated poly(l-lysine) dendrimer-camptothecin conjugates. Mol Pharm. 2009 Sep-Oct; 6(5):1562-72. View on Pubmed
  240. Fox ME, Szoka FC, Fréchet JM. Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture. Acc Chem Res. 2009 Aug 18; 42(8):1141-51. View on Pubmed
  241. Huang Z, Hwang P, Watson DS, Cao L, Szoka FC. Tris-nitrilotriacetic acids of subnanomolar affinity toward hexahistidine tagged molecules. Bioconjug Chem. 2009 Aug 19; 20(8):1667-72. View on Pubmed
  242. Watson DS, Huang Z, Szoka FC. All-trans retinoic acid potentiates the antibody response in mice to a lipopeptide antigen adjuvanted with liposomal lipid A. Immunol Cell Biol. 2009 Nov-Dec; 87(8):630-3. View on Pubmed
  243. Watson DS, Szoka FC. Role of lipid structure in the humoral immune response in mice to covalent lipid-peptides from the membrane proximal region of HIV-1 gp41. Vaccine. 2009 Jul 23; 27(34):4672-83. View on Pubmed
  244. Chen B, Jerger K, Fréchet JM, Szoka FC. The influence of polymer topology on pharmacokinetics: differences between cyclic and linear PEGylated poly(acrylic acid) comb polymers. J Control Release. 2009 Dec 16; 140(3):203-9. View on Pubmed
  245. Park JI, Cao L, Platt VM, Huang Z, Stull RA, Dy EE, Sperinde JJ, Yokoyama JS, Szoka FC. Antitumor therapy mediated by 5-fluorocytosine and a recombinant fusion protein containing TSG-6 hyaluronan binding domain and yeast cytosine deaminase. Mol Pharm. 2009 May-Jun; 6(3):801-12. View on Pubmed
  246. Nasongkla N, Chen B, Macaraeg N, Fox ME, Fréchet JM, Szoka FC. Dependence of pharmacokinetics and biodistribution on polymer architecture: effect of cyclic versus linear polymers. J Am Chem Soc. 2009 Mar 25; 131(11):3842-3. View on Pubmed
  247. Cohen RN, van der Aa MA, Macaraeg N, Lee AP, Szoka FC. Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection. J Control Release. 2009 Apr 17; 135(2):166-74. View on Pubmed
  248. Huang Z, Jaafari MR, Szoka FC. Disterolphospholipids: nonexchangeable lipids and their application to liposomal drug delivery. Angew Chem Int Ed Engl. 2009; 48(23):4146-9. View on Pubmed
  249. Huang Z, Szoka FC. Sterol-modified phospholipids: cholesterol and phospholipid chimeras with improved biomembrane properties. J Am Chem Soc. 2008 Nov 19; 130(46):15702-12. View on Pubmed
  250. Platt VM, Szoka FC. Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor. Mol Pharm. 2008 Jul-Aug; 5(4):474-86. View on Pubmed
  251. MacKay JA, Li W, Huang Z, Dy EE, Huynh G, Tihan T, Collins R, Deen DF, Szoka FC. HIV TAT peptide modifies the distribution of DNA nanolipoparticles following convection-enhanced delivery. Mol Ther. 2008 May; 16(5):893-900. View on Pubmed
  252. Szoka F. Molecular biology. The art of assembly. Science. 2008 Feb 01; 319(5863):578-9. View on Pubmed
  253. Guillaudeu SJ, Fox ME, Haidar YM, Dy EE, Szoka FC, Fréchet JM. PEGylated dendrimers with core functionality for biological applications. Bioconjug Chem. 2008 Feb; 19(2):461-9. View on Pubmed
  254. Chen H, Zhang H, McCallum CM, Szoka FC, Guo X. Unsaturated cationic ortho esters for endosome permeation in gene delivery. J Med Chem. 2007 Sep 06; 50(18):4269-78. View on Pubmed
  255. Li W, Suez I, Szoka FC. Reconstitution of the M13 major coat protein and its transmembrane peptide segment on a DNA template. Biochemistry. 2007 Jul 24; 46(29):8579-91. View on Pubmed
  256. Karpuj MV, Giles K, Gelibter-Niv S, Scott MR, Lingappa VR, Szoka FC, Peretz D, Denetclaw W, Prusiner SB. Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells. Mol Med. 2007 Mar-Apr; 13(3-4):190-8. View on Pubmed
  257. Li W, Szoka FC. Lipid-based nanoparticles for nucleic acid delivery. Pharm Res. 2007 Mar; 24(3):438-49. View on Pubmed
  258. Huynh GH, Ozawa T, Deen DF, Tihan T, Szoka FC. Retro-convection enhanced delivery to increase blood to brain transfer of macromolecules. Brain Res. 2007 Jan 12; 1128(1):181-90. View on Pubmed
  259. Huang Z, Park JI, Watson DS, Hwang P, Szoka FC. Facile synthesis of multivalent nitrilotriacetic acid (NTA) and NTA conjugates for analytical and drug delivery applications. Bioconjug Chem. 2006 Nov-Dec; 17(6):1592-600. View on Pubmed
  260. Lee CC, Gillies ER, Fox ME, Guillaudeu SJ, Fréchet JM, Dy EE, Szoka FC. A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16649-54. View on Pubmed
  261. Lee CC, Cramer AT, Szoka FC, Fréchet JM. An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin. Bioconjug Chem. 2006 Sep-Oct; 17(5):1364-8. View on Pubmed
  262. Ruhela D, Riviere K, Szoka FC. Efficient synthesis of an aldehyde functionalized hyaluronic acid and its application in the preparation of hyaluronan-lipid conjugates. Bioconjug Chem. 2006 Sep-Oct; 17(5):1360-3. View on Pubmed
  263. Li W, Szoka FC. Bioresponsive targeted charge neutral lipid vesicles for systemic gene delivery. CSH Protoc. 2006 Jun 01; 2006(1). View on Pubmed
  264. Huang Z, Guo X, Li W, MacKay JA, Szoka FC. Acid-triggered transformation of diortho ester phosphocholine liposome. J Am Chem Soc. 2006 Jan 11; 128(1):60-1. View on Pubmed
  265. Lee CC, MacKay JA, Fréchet JM, Szoka FC. Designing dendrimers for biological applications. Nat Biotechnol. 2005 Dec; 23(12):1517-26. View on Pubmed
  266. Huynh GH, Deen DF, Szoka FC. Barriers to carrier mediated drug and gene delivery to brain tumors. J Control Release. 2006 Jan 10; 110(2):236-59. View on Pubmed
  267. Lee CC, Yoshida M, Fréchet JM, Dy EE, Szoka FC. In vitro and in vivo evaluation of hydrophilic dendronized linear polymers. Bioconjug Chem. 2005 May-Jun; 16(3):535-41. View on Pubmed
  268. Gillies ER, Dy E, Fréchet JM, Szoka FC. Biological evaluation of polyester dendrimer: poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture. Mol Pharm. 2005 Mar-Apr; 2(2):129-38. View on Pubmed
  269. Tang MX, Li W, Szoka FC. Toroid formation in charge neutralized flexible or semi-flexible biopolymers: potential pathway for assembly of DNA carriers. J Gene Med. 2005 Mar; 7(3):334-42. View on Pubmed
  270. Huang Z, Li W, MacKay JA, Szoka FC. Thiocholesterol-based lipids for ordered assembly of bioresponsive gene carriers. Mol Ther. 2005 Mar; 11(3):409-17. View on Pubmed
  271. Choi SJ, Sperinde JJ, Szoka FC. Identification of a deoxyribonuclease I inhibitor from a phage-peptide library. Mol Cells. 2005 Feb 28; 19(1):54-9. View on Pubmed
  272. MacKay JA, Deen DF, Szoka FC. Distribution in brain of liposomes after convection enhanced delivery; modulation by particle charge, particle diameter, and presence of steric coating. Brain Res. 2005 Feb 28; 1035(2):139-53. View on Pubmed
  273. Li W, Huang Z, MacKay JA, Grube S, Szoka FC. Low-pH-sensitive poly(ethylene glycol) (PEG)-stabilized plasmid nanolipoparticles: effects of PEG chain length, lipid composition and assembly conditions on gene delivery. J Gene Med. 2005 Jan; 7(1):67-79. View on Pubmed
  274. Cohen RN, Rashkin MJ, Wen X, Szoka FC. Molecular motors as drug delivery vehicles. Drug Discov Today Technol. 2005; 2(1):111-8. View on Pubmed
  275. Li W, Nicol F, Szoka FC. GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery. Adv Drug Deliv Rev. 2004 Apr 23; 56(7):967-85. View on Pubmed
  276. Eliaz RE, Nir S, Marty C, Szoka FC. Determination and modeling of kinetics of cancer cell killing by doxorubicin and doxorubicin encapsulated in targeted liposomes. Cancer Res. 2004 Jan 15; 64(2):711-8. View on Pubmed
  277. Guo X, Huang Z, Szoka FC. Improved preparation of PEG-diortho ester-diacyl glycerol conjugates. Methods Enzymol. 2004; 387:147-52. View on Pubmed
  278. Eliaz RE, Nir S, Szoka FC. Interactions of hyaluronan-targeted liposomes with cultured cells: modeling of binding and endocytosis. Methods Enzymol. 2004; 387:16-33. View on Pubmed
  279. Sonawane ND, Szoka FC, Verkman AS. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem. 2003 Nov 07; 278(45):44826-31. View on Pubmed
  280. Guo X, Szoka FC. Chemical approaches to triggerable lipid vesicles for drug and gene delivery. Acc Chem Res. 2003 May; 36(5):335-41. View on Pubmed
  281. Choi JS, MacKay JA, Szoka FC. Low-pH-sensitive PEG-stabilized plasmid-lipid nanoparticles: preparation and characterization. Bioconjug Chem. 2003 Mar-Apr; 14(2):420-9. View on Pubmed
  282. Guo X, MacKay JA, Szoka FC. Mechanism of pH-triggered collapse of phosphatidylethanolamine liposomes stabilized by an ortho ester polyethyleneglycol lipid. Biophys J. 2003 Mar; 84(3):1784-95. View on Pubmed
  283. Swanson B, Savel R, Szoka F, Sawa T, Wiener-Kronish J. Development of a high throughput Pseudomonas aeruginosa epithelial cell adhesion assay. J Microbiol Methods. 2003 Mar; 52(3):361-6. View on Pubmed
  284. Mackay JA, Szoka FC. HIV TAT Protein Transduction Domain Mediated Cell Binding and Intracellular Delivery of Nanoparticles. J Dispers Sci Technol. 2003; 24(3):465-473. View on Pubmed
  285. Bronich TK, Ouyang M, Kabanov VA, Eisenberg A, Szoka FC, Kabanov AV. Synthesis of vesicles on polymer template. J Am Chem Soc. 2002 Oct 09; 124(40):11872-3. View on Pubmed
  286. Eliaz RE, Szoka FC. Robust and prolonged gene expression from injectable polymeric implants. Gene Ther. 2002 Sep; 9(18):1230-7. View on Pubmed
  287. Padilla De Jesús OL, Ihre HR, Gagne L, Fréchet JM, Szoka FC. Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation. Bioconjug Chem. 2002 May-Jun; 13(3):453-61. View on Pubmed
  288. Ihre HR, Padilla De Jesús OL, Szoka FC, Fréchet JM. Polyester dendritic systems for drug delivery applications: design, synthesis, and characterization. Bioconjug Chem. 2002 May-Jun; 13(3):443-52. View on Pubmed
  289. Uyechi LS, Gagné L, Thurston G, Szoka FC. Mechanism of lipoplex gene delivery in mouse lung: binding and internalization of fluorescent lipid and DNA components. Gene Ther. 2001 Jun; 8(11):828-36. View on Pubmed
  290. Supattapone S, Wille H, Uyechi L, Safar J, Tremblay P, Szoka FC, Cohen FE, Prusiner SB, Scott MR. Branched polyamines cure prion-infected neuroblastoma cells. J Virol. 2001 Apr; 75(7):3453-61. View on Pubmed
  291. Eliaz RE, Szoka FC. Liposome-encapsulated doxorubicin targeted to CD44: a strategy to kill CD44-overexpressing tumor cells. Cancer Res. 2001 Mar 15; 61(6):2592-601. View on Pubmed
  292. Guo X, Szoka FC. Steric stabilization of fusogenic liposomes by a low-pH sensitive PEG--diortho ester--lipid conjugate. Bioconjug Chem. 2001 Mar-Apr; 12(2):291-300. View on Pubmed
  293. Sperinde JJ, Choi SJ, Szoka FC. Phage display selection of a peptide DNase II inhibitor that enhances gene delivery. J Gene Med. 2001 Mar-Apr; 3(2):101-8. View on Pubmed
  294. Sparrer HE, Santoso A, Szoka FC, Weissman JS. Evidence for the prion hypothesis: induction of the yeast [PSI+] factor by in vitro- converted Sup35 protein. Science. 2000 Jul 28; 289(5479):595-9. View on Pubmed
  295. Choi SJ, Szoka FC. Fluorometric determination of deoxyribonuclease I activity with PicoGreen. Anal Biochem. 2000 May 15; 281(1):95-7. View on Pubmed
  296. Nicol F, Nir S, Szoka FC. Effect of phospholipid composition on an amphipathic peptide-mediated pore formation in bilayer vesicles. Biophys J. 2000 Feb; 78(2):818-29. View on Pubmed
  297. Ouyang M, Remy JS, Szoka FC. Controlled template-assisted assembly of plasmid DNA into nanometric particles with high DNA concentration. Bioconjug Chem. 2000 Jan-Feb; 11(1):104-12. View on Pubmed
  298. Urtti A, Polansky J, Lui GM, Szoka FC. Gene delivery and expression in human retinal pigment epithelial cells: effects of synthetic carriers, serum, extracellular matrix and viral promoters. J Drug Target. 2000; 7(6):413-21. View on Pubmed
  299. Hirota S, de Ilarduya CT, Barron LG, Szoka FC. Simple mixing device to reproducibly prepare cationic lipid-DNA complexes (lipoplexes). Biotechniques. 1999 Aug; 27(2):286-90. View on Pubmed
  300. Barron LG, Gagné L, Szoka FC. Lipoplex-mediated gene delivery to the lung occurs within 60 minutes of intravenous administration. Hum Gene Ther. 1999 Jul 01; 10(10):1683-94. View on Pubmed
  301. Xu Y, Hui SW, Frederik P, Szoka FC. Physicochemical characterization and purification of cationic lipoplexes. Biophys J. 1999 Jul; 77(1):341-53. View on Pubmed
  302. Barron LG, Uyechi LS, Szoka FC. Cationic lipids are essential for gene delivery mediated by intravenous administration of lipoplexes. Gene Ther. 1999 Jun; 6(6):1179-83. View on Pubmed
  303. Nicol F, Nir S, Szoka FC. Orientation of the pore-forming peptide GALA in POPC vesicles determined by a BODIPY-avidin/biotin binding assay. Biophys J. 1999 Apr; 76(4):2121-41. View on Pubmed
  304. Plank C, Tang MX, Wolfe AR, Szoka FC. Branched cationic peptides for gene delivery: role of type and number of cationic residues in formation and in vitro activity of DNA polyplexes. Hum Gene Ther. 1999 Jan 20; 10(2):319-32. View on Pubmed
  305. Nir S, Nicol F, Szoka FC. Surface aggregation and membrane penetration by peptides: relation to pore formation and fusion. Mol Membr Biol. 1999 Jan-Mar; 16(1):95-101. View on Pubmed
  306. Turunen MP, Hiltunen MO, Ruponen M, Virkamäki L, Szoka FC, Urtti A, Ylä-Herttuala S. Efficient adventitial gene delivery to rabbit carotid artery with cationic polymer-plasmid complexes. Gene Ther. 1999 Jan; 6(1):6-11. View on Pubmed
  307. Peschka R, Dennehy C, Szoka FC. A simple in vitro model to study the release kinetics of liposome encapsulated material. J Control Release. 1998 Dec 04; 56(1-3):41-51. View on Pubmed
  308. Davis SC, Szoka FC. Cholesterol phosphate derivatives: synthesis and incorporation into a phosphatase and calcium-sensitive triggered release liposome. Bioconjug Chem. 1998 Nov-Dec; 9(6):783-92. View on Pubmed
  309. Wang J, Guo X, Xu Y, Barron L, Szoka FC. Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery. J Med Chem. 1998 Jun 18; 41(13):2207-15. View on Pubmed
  310. Zelphati O, Uyechi LS, Barron LG, Szoka FC. Effect of serum components on the physico-chemical properties of cationic lipid/oligonucleotide complexes and on their interactions with cells. Biochim Biophys Acta. 1998 Feb 16; 1390(2):119-33. View on Pubmed
  311. Barron LG, Meyer KB, Szoka FC. Effects of complement depletion on the pharmacokinetics and gene delivery mediated by cationic lipid-DNA complexes. Hum Gene Ther. 1998 Feb 10; 9(3):315-23. View on Pubmed
  312. Swaan PW, Szoka FC, Oie S. Molecular modeling of the intestinal bile acid carrier: a comparative molecular field analysis study. J Comput Aided Mol Des. 1997 Nov; 11(6):581-8. View on Pubmed
  313. Tang MX, Szoka FC. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther. 1997 Aug; 4(8):823-32. View on Pubmed
  314. Swaan PW, Hillgren KM, Szoka FC, Oie S. Enhanced transepithelial transport of peptides by conjugation to cholic acid. Bioconjug Chem. 1997 Jul-Aug; 8(4):520-5. View on Pubmed
  315. Szoka FC. Many are probed, but few are chosen. Nat Biotechnol. 1997 Jun; 15(6):509. View on Pubmed
  316. Felgner PL, Barenholz Y, Behr JP, Cheng SH, Cullis P, Huang L, Jessee JA, Seymour L, Szoka F, Thierry AR, Wagner E, Wu G. Nomenclature for synthetic gene delivery systems. Hum Gene Ther. 1997 Mar 20; 8(5):511-2. View on Pubmed
  317. Wyman TB, Nicol F, Zelphati O, Scaria PV, Plank C, Szoka FC. Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry. 1997 Mar 11; 36(10):3008-17. View on Pubmed
  318. Kågedahl M, Swaan PW, Redemann CT, Tang M, Craik CS, Szoka FC, Oie S. Use of the intestinal bile acid transporter for the uptake of cholic acid conjugates with HIV-1 protease inhibitory activity. Pharm Res. 1997 Feb; 14(2):176-80. View on Pubmed
  319. Nicol F, Nir S, Szoka FC. Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide. Biophys J. 1996 Dec; 71(6):3288-301. View on Pubmed
  320. Tang MX, Redemann CT, Szoka FC. In vitro gene delivery by degraded polyamidoamine dendrimers. Bioconjug Chem. 1996 Nov-Dec; 7(6):703-14. View on Pubmed
  321. Zelphati O, Szoka FC. Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11493-8. View on Pubmed
  322. Zelphati O, Szoka FC. Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids. Pharm Res. 1996 Sep; 13(9):1367-72. View on Pubmed
  323. Plank C, Mechtler K, Szoka FC, Wagner E. Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. Hum Gene Ther. 1996 Aug 01; 7(12):1437-46. View on Pubmed
  324. Xu Y, Szoka FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry. 1996 May 07; 35(18):5616-23. View on Pubmed
  325. van der Geest R, Hueber F, Szoka FC, Guy RH. Iontophoresis of bases, nucleosides, and nucleotides. Pharm Res. 1996 Apr; 13(4):553-8. View on Pubmed
  326. Levy MY, Barron LG, Meyer KB, Szoka FC. Characterization of plasmid DNA transfer into mouse skeletal muscle: evaluation of uptake mechanism, expression and secretion of gene products into blood. Gene Ther. 1996 Mar; 3(3):201-11. View on Pubmed
  327. Stull RA, Zon G, Szoka FC. An in vitro messenger RNA binding assay as a tool for identifying hybridization-competent antisense oligonucleotides. Antisense Nucleic Acid Drug Dev. 1996; 6(3):221-8. View on Pubmed
  328. Meyer KB, Thompson MM, Levy MY, Barron LG, Szoka FC. Intratracheal gene delivery to the mouse airway: characterization of plasmid DNA expression and pharmacokinetics. Gene Ther. 1995 Sep; 2(7):450-60. View on Pubmed
  329. Stull RA, Szoka FC. Antigene, ribozyme and aptamer nucleic acid drugs: progress and prospects. Pharm Res. 1995 Apr; 12(4):465-83. View on Pubmed
  330. Hickman MA, Malone RW, Lehmann-Bruinsma K, Sih TR, Knoell D, Szoka FC, Walzem R, Carlson DM, Powell JS. Gene expression following direct injection of DNA into liver. Hum Gene Ther. 1994 Dec; 5(12):1477-83. View on Pubmed
  331. Fattal E, Nir S, Parente RA, Szoka FC. Pore-forming peptides induce rapid phospholipid flip-flop in membranes. Biochemistry. 1994 May 31; 33(21):6721-31. View on Pubmed
  332. Sixou S, Szoka FC, Green GA, Giusti B, Zon G, Chin DJ. Intracellular oligonucleotide hybridization detected by fluorescence resonance energy transfer (FRET). Nucleic Acids Res. 1994 Feb 25; 22(4):662-8. View on Pubmed
  333. Haensler J, Szoka FC. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug Chem. 1993 Sep-Oct; 4(5):372-9. View on Pubmed
  334. Legendre JY, Szoka FC. Cyclic amphipathic peptide-DNA complexes mediate high-efficiency transfection of adherent mammalian cells. Proc Natl Acad Sci U S A. 1993 Feb 01; 90(3):893-7. View on Pubmed
  335. Stull RA, Zon G, Szoka FC. Single-stranded phosphodiester and phosphorothioate oligonucleotides bind actinomycin D and interfere with tumor necrosis factor-induced lysis in the L929 cytotoxicity assay. Antisense Res Dev. 1993; 3(3):295-300. View on Pubmed
  336. Haensler J, Szoka FC. Synthesis and characterization of a trigalactosylated bisacridine compound to target DNA to hepatocytes. Bioconjug Chem. 1993 Jan-Feb; 4(1):85-93. View on Pubmed
  337. Legendre JY, Szoka FC. Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: comparison with cationic liposomes. Pharm Res. 1992 Oct; 9(10):1235-42. View on Pubmed
  338. Stull RA, Taylor LA, Szoka FC. Predicting antisense oligonucleotide inhibitory efficacy: a computational approach using histograms and thermodynamic indices. Nucleic Acids Res. 1992 Jul 11; 20(13):3501-8. View on Pubmed
  339. Kim A, Szoka FC. Amino acid side-chain contributions to free energy of transfer of tripeptides from water to octanol. Pharm Res. 1992 Apr; 9(4):504-14. View on Pubmed
  340. Woodle MC, Storm G, Newman MS, Jekot JJ, Collins LR, Martin FJ, Szoka FC. Prolonged systemic delivery of peptide drugs by long-circulating liposomes: illustration with vasopressin in the Brattleboro rat. Pharm Res. 1992 Feb; 9(2):260-5. View on Pubmed
  341. Szoka FC. The macrophage as the principal antigen-presenting cell for liposome-encapsulated antigen. Res Immunol. 1992 Feb; 143(2):186-8. View on Pubmed
  342. Green PG, Hinz RS, Kim A, Szoka FC, Guy RH. Iontophoretic delivery of a series of tripeptides across the skin in vitro. Pharm Res. 1991 Sep; 8(9):1121-7. View on Pubmed
  343. Goormaghtigh E, De Meutter J, Szoka F, Cabiaux V, Parente RA, Ruysschaert JM. Secondary structure and orientation of the amphipathic peptide GALA in lipid structures. An infrared-spectroscopic approach. Eur J Biochem. 1991 Jan 30; 195(2):421-9. View on Pubmed
  344. Chin DJ, Green GA, Zon G, Szoka FC, Straubinger RM. Rapid nuclear accumulation of injected oligodeoxyribonucleotides. New Biol. 1990 Dec; 2(12):1091-100. View on Pubmed
  345. Szoka FC. The future of liposomal drug delivery. Biotechnol Appl Biochem. 1990 Oct; 12(5):496-500. View on Pubmed
  346. Parente RA, Nadasdi L, Subbarao NK, Szoka FC. Association of a pH-sensitive peptide with membrane vesicles: role of amino acid sequence. Biochemistry. 1990 Sep 18; 29(37):8713-9. View on Pubmed
  347. Parente RA, Nir S, Szoka FC. Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA. Biochemistry. 1990 Sep 18; 29(37):8720-8. View on Pubmed
  348. Chu CJ, Dijkstra J, Lai MZ, Hong K, Szoka FC. Efficiency of cytoplasmic delivery by pH-sensitive liposomes to cells in culture. Pharm Res. 1990 Aug; 7(8):824-34. View on Pubmed
  349. Roe JN, Szoka FC, Verkman AS. Fibre optic sensor for the detection of potassium using fluorescence energy transfer. Analyst. 1990 Apr; 115(4):353-8. View on Pubmed
  350. Dal Monte PR, Szoka FC. Antigen presentation by B cells and macrophages of cytochrome c and its antigenic fragment when conjugated to the surface of liposomes. Vaccine. 1989 Oct; 7(5):401-8. View on Pubmed
  351. Roe JN, Szoka FC, Verkman AS. Optical measurement of aqueous potassium concentration by a hydrophobic indicator in lipid vesicles. Biophys Chem. 1989 Jul; 33(3):295-302. View on Pubmed
  352. Patterson TF, Miniter P, Dijkstra J, Szoka FC, Ryan JL, Andriole VT. Treatment of experimental invasive aspergillosis with novel amphotericin B/cholesterol-sulfate complexes. J Infect Dis. 1989 Apr; 159(4):717-24. View on Pubmed
  353. Dal Monte P, Szoka FC. Effect of liposome encapsulation on antigen presentation in vitro. Comparison of presentation by peritoneal macrophages and B cell tumors. J Immunol. 1989 Mar 01; 142(5):1437-43. View on Pubmed
  354. Dijkstra J, Ryan JL, Szoka FC. A procedure for the efficient incorporation of wild-type lipopolysaccharide into liposomes for use in immunological studies. J Immunol Methods. 1988 Nov 10; 114(1-2):197-205. View on Pubmed
  355. Szoka FC, Chu CJ. Increased efficacy of phosphonoformate and phosphonoacetate inhibition of herpes simplex virus type 2 replication by encapsulation in liposomes. Antimicrob Agents Chemother. 1988 Jun; 32(6):858-64. View on Pubmed
  356. Dijkstra J, Larrick JW, Ryan JL, Szoka FC. Incorporation of LPS in liposomes diminishes its ability to induce tumoricidal activity and tumor necrosis factor secretion in murine macrophages. J Leukoc Biol. 1988 May; 43(5):436-44. View on Pubmed
  357. Parente RA, Nir S, Szoka FC. pH-dependent fusion of phosphatidylcholine small vesicles. Induction by a synthetic amphipathic peptide. J Biol Chem. 1988 Apr 05; 263(10):4724-30. View on Pubmed
  358. Subbarao NK, Fielding CJ, Hamilton RL, Szoka FC. Lecithin:cholesterol acyltransferase activation by synthetic amphipathic peptides. Proteins. 1988; 3(3):187-98. View on Pubmed
  359. Subbarao NK, Parente RA, Szoka FC, Nadasdi L, Pongracz K. pH-dependent bilayer destabilization by an amphipathic peptide. Biochemistry. 1987 Jun 02; 26(11):2964-72. View on Pubmed
  360. Barza M, Stuart M, Szoka F. Effect of size and lipid composition on the pharmacokinetics of intravitreal liposomes. Invest Ophthalmol Vis Sci. 1987 May; 28(5):893-900. View on Pubmed
  361. Bentz J, Ellens H, Szoka FC. Destabilization of phosphatidylethanolamine-containing liposomes: hexagonal phase and asymmetric membranes. Biochemistry. 1987 Apr 21; 26(8):2105-16. View on Pubmed
  362. Dijkstra J, Mellors JW, Ryan JL, Szoka FC. Modulation of the biological activity of bacterial endotoxin by incorporation into liposomes. J Immunol. 1987 Apr 15; 138(8):2663-70. View on Pubmed
  363. Szoka FC, Milholland D, Barza M. Effect of lipid composition and liposome size on toxicity and in vitro fungicidal activity of liposome-intercalated amphotericin B. Antimicrob Agents Chemother. 1987 Mar; 31(3):421-9. View on Pubmed
  364. Szoka FC, Jones CS. Uptake of liposome-encapsulated agents. Methods Enzymol. 1987; 149:143-7. View on Pubmed
  365. Ellens H, Bentz J, Szoka FC. Fusion of phosphatidylethanolamine-containing liposomes and mechanism of the L alpha-HII phase transition. Biochemistry. 1986 Jul 15; 25(14):4141-7. View on Pubmed
  366. Ellens H, Bentz J, Szoka FC. Destabilization of phosphatidylethanolamine liposomes at the hexagonal phase transition temperature. Biochemistry. 1986 Jan 28; 25(2):285-94. View on Pubmed
  367. Bentz J, Ellens H, Lai MZ, Szoka FC. On the correlation between HII phase and the contact-induced destabilization of phosphatidylethanolamine-containing membranes. Proc Natl Acad Sci U S A. 1985 Sep; 82(17):5742-5. View on Pubmed
  368. Barza M, Baum J, Tremblay C, Szoka F, D'Amico DJ. Ocular toxicity of intravitreally injected liposomal amphotericin B in rhesus monkeys. Am J Ophthalmol. 1985 Aug 15; 100(2):259-63. View on Pubmed
  369. Ellens H, Bentz J, Szoka FC. H+- and Ca2+-induced fusion and destabilization of liposomes. Biochemistry. 1985 Jun 18; 24(13):3099-106. View on Pubmed
  370. Tremblay C, Barza M, Szoka F, Lahav M, Baum J. Reduced toxicity of liposome-associated amphotericin B injected intravitreally in rabbits. Invest Ophthalmol Vis Sci. 1985 May; 26(5):711-8. View on Pubmed
  371. Lai MZ, Vail WJ, Szoka FC. Acid- and calcium-induced structural changes in phosphatidylethanolamine membranes stabilized by cholesteryl hemisuccinate. Biochemistry. 1985 Mar 26; 24(7):1654-61. View on Pubmed
  372. Lai MZ, Düzgünes N, Szoka FC. Effects of replacement of the hydroxyl group of cholesterol and tocopherol on the thermotropic behavior of phospholipid membranes. Biochemistry. 1985 Mar 26; 24(7):1646-53. View on Pubmed
  373. Tremblay C, Barza M, Fiore C, Szoka F. Efficacy of liposome-intercalated amphotericin B in the treatment of systemic candidiasis in mice. Antimicrob Agents Chemother. 1984 Aug; 26(2):170-3. View on Pubmed
  374. Panosian CB, Barza M, Szoka F, Wyler DJ. Treatment of experimental cutaneous leishmaniasis with liposome-intercalated amphotericin B. Antimicrob Agents Chemother. 1984 May; 25(5):655-6. View on Pubmed
  375. Barza M, Baum J, Szoka F. Pharmacokinetics of subconjunctival liposome-encapsulated gentamicin in normal rabbit eyes. Invest Ophthalmol Vis Sci. 1984 Apr; 25(4):486-90. View on Pubmed
  376. Ellens H, Bentz J, Szoka FC. pH-induced destabilization of phosphatidylethanolamine-containing liposomes: role of bilayer contact. Biochemistry. 1984 Mar 27; 23(7):1532-8. View on Pubmed
  377. Szoka FC, Mayhew E. Alteration of liposome disposition in vivo by bilayer situated carbohydrates. Biochem Biophys Res Commun. 1983 Jan 14; 110(1):140-6. View on Pubmed
  378. Abra RM, Schreier H, Szoka FC. The use of a new radioactive-iodine labeled lipid marker to follow in vivo disposition of liposomes: comparison with an encapsulated aqueous space marker. Res Commun Chem Pathol Pharmacol. 1982 Aug; 37(2):199-213. View on Pubmed
  379. Alroy J, Szoka FC, Heaney JA, Ucci AA. Lectins as a probe for carbohydrate residues in non-neoplastic urothelium of human urinary bladder. J Urol. 1982 Jul; 128(1):189-93. View on Pubmed
  380. Olson F, Mayhew E, Maslow D, Rustum Y, Szoka F. Characterization, toxicity and therapeutic efficacy of adriamycin encapsulated in liposomes. Eur J Cancer Clin Oncol. 1982 Feb; 18(2):167-76. View on Pubmed
  381. Kirkland JJ, Yau WW, Szoka FC. Sedimentation field flow fractionation of liposomes. Science. 1982 Jan 15; 215(4530):296-8. View on Pubmed
  382. Rustum YM, Mayhew E, Szoka F, Campbell J. Inability of liposome encapsulated 1-beta-D-arabinofuranosylcytosine nucleotides to overcome drug resistance in L1210 cells. Eur J Cancer Clin Oncol. 1981 Jul; 17(7):809-17. View on Pubmed
  383. Szoka F, Magnusson KE, Wojcieszyn J, Hou Y, Derzko Z, Jacobson K. Use of lectins and polyethylene glycol for fusion of glycolipid-containing liposomes with eukaryotic cells. Proc Natl Acad Sci U S A. 1981 Mar; 78(3):1685-9. View on Pubmed
  384. Szoka F, Olson F, Heath T, Vail W, Mayhew E, Papahadjopoulos D. Preparation of unilamellar liposomes of intermediate size (0.1-0.2 mumol) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes. Biochim Biophys Acta. 1980 Oct 02; 601(3):559-71. View on Pubmed
  385. Szoka F, Jacobson K, Derzko Z, Papahadjopoulos D. Fluorescence studies on the mechanism of liposome-cell interactions in vitro. Biochim Biophys Acta. 1980 Jul 16; 600(1):1-18. View on Pubmed
  386. Szoka F, Papahadjopoulos D. Comparative properties and methods of preparation of lipid vesicles (liposomes). Annu Rev Biophys Bioeng. 1980; 9:467-508. View on Pubmed
  387. Mayhew E, Rustum YM, Szoka F, Papahadjopoulos D. Role of cholesterol in enhancing the antitumor activity of cytosine arabinoside entrapped in liposomes. Cancer Treat Rep. 1979 Nov-Dec; 63(11-12):1923-8. View on Pubmed
  388. Near JA, Szoka FC, Olsen R, Ettinger MJ. Photoaffinity labeling of three renal cyclic 3',5'-adenosine monophosphate-binding proteins. Biochim Biophys Acta. 1979 Nov 01; 587(4):522-39. View on Pubmed
  389. Olson F, Hunt CA, Szoka FC, Vail WJ, Papahadjopoulos D. Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes. Biochim Biophys Acta. 1979 Oct 19; 557(1):9-23. View on Pubmed
  390. Saffran M, Franco-Saenz R, Kong A, Papahadjopoulos D, Szoka F. A model for the study of the oral administration of peptide hormones. Can J Biochem. 1979 Jun; 57(6):548-53. View on Pubmed
  391. Szoka FC, Jacobson K, Papahadjopoulos D. The use of aqueous space markers to determine the mechanism of interaction between phospholipid vesicles and cells. Biochim Biophys Acta. 1979 Mar 08; 551(2):295-303. View on Pubmed
  392. Wu ES, Jacobson K, Szoka F, Portis A. Lateral diffusion of a hydrophobic peptide, N-4-nitrobenz-2-oxa-1,3-diazole gramicidin S, in phospholipid multibilayers. Biochemistry. 1978 Dec 12; 17(25):5543-50. View on Pubmed
  393. Szoka FC, Ettinger MJ. Adenosine 3' :5' -monophosphate-dependnet phosphorylations of renal subcellular fractions. Differences between cortical and medullary membrane preparations. J Biol Chem. 1978 Sep 25; 253(18):6536-43. View on Pubmed
  394. Szoka F, Papahadjopoulos D. Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation. Proc Natl Acad Sci U S A. 1978 Sep; 75(9):4194-8. View on Pubmed