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CFAR Logo

CFAR Science: Overview

UCSF-GIVI Center for AIDS Research

About CFAR Science

CFAR Scientific Model

Research Model:
The UCSF-GIVI Center for AIDS Research seeks to expand HIV research occuring at the intersections of basic, clinical and behavioral/epidemiological scientific disciplines.

Our Center's central goal is facilitating scientific progress in HIV by providing the broadest community of member investigators with direct services and other means that result in important collaborative work. CFAR continuallly works to assemble scientific teams across our distributed research environment and supports those efforts with direct and indirect resources such as access to emerging technologies and availability of dynamic scientific cores.

Accordingly, CFAR-supported science seeks to address the full diversity of the HIV/AIDS epidemic, domestic and international, while encouraging new collaborations among teams of investigators at UCSF and our partner institutes. CFAR provides key resources to enhance the effectiveness of those teams in addressing the most important, cutting-edge questions in HIV research. Below are areas of HIV/AIDS research, current or planned, where CFAR is galvanizing scientific exploration.

Basic-Clinical Intersection

  1. What will be the clinical impact of CCR5 inhibitors?
  2. Will it ever be possible to "cure" HIV-infected patients?
  3. Why do "elite suppressors" so effectively resist HIV infection and spread?
  4. What is the role of chronic immune activation in HIV pathogenesis?
  5. How, when and where does HIV mucosal infection occur?
  6. What are the clinical and biological implications for transmission of drug-resistant HIV?

Clinical-Behavioral Intersection

Basic-Behavioral Intersection

Basic-Clinical-Behavioral Intersection

National CFAR Program - Supplemental Award Projects

These collaborative projects are distinct within our CFAR's larger translational mission, as they are typically submitted in response to an RFA issued by those NIH agencies within the National CFAR program, and focus on scientific questions specific to the issuing institute(s) particular area of HIV/AIDS exploration. These supplements are administered directly by our center and require utilization of one or more of our research cores.

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